Supercritical drying of alginate beads for the development of aerogel biomaterials: Optimization of process parameters and exchange solvents

Industrial and Engineering Chemistry Research

Volumn 52, Issue 34, 2013, Pages 12003-12009

  Della Porta, Giovanna ^a   Del Gaudio, Pasquale ^a   De Cicco, Felicetta ^a   Aquino, Rita P ^a   Reverchon, Ernesto ^a  

^a UNIVERSITY OF SALERNO   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALGINATE HYDROGELS; DRYING TECHNIQUE; INTERNAL STRUCTURE; OPTIMIZATION OF PROCESS PARAMETERS; SOLVENT EXCHANGES; SUPERCRITICAL DRYING; SUPERCRITICAL EXTRACTION; WATER/ETHANOL MIXTURES;

ACETONE; BIOLOGICAL MATERIALS; DRYING; ETHANOL; HYDROGELS; MIXTURES; NANOSTRUCTURES; ORGANIC SOLVENTS; SHRINKAGE; SOLVENTS; SUPERCRITICAL FLUID EXTRACTION;

AEROGELS;

EID: 84883388207     PISSN: 08885885     EISSN: 15205045     Source Type: Journal    
DOI: 10.1021/ie401335c     Document Type: Article

References (36)

1. Bhattarai, N.; Li, Z.; Edmondson, D.; Zhang, M. Alginate-based nanofibrous scaffolds: Structural, mechanical, and biological properties Adv. Mater. 2006, 18, 1463
2. Drury, J. L.; Mooney David, J. Hydrogels for tissue engineering: Scaffold design variables and applications Biomaterials 2003, 24, 4337
3. Del Gaudio, P.; Colombo, P.; Colombo, G.; Russo, P.; Sonvico, F. Mechanisms of formation and disintegration of alginate beads obtained by prilling Int. J. Pharm. 2005, 302, 1
4. Bellich, B.; Borgogna, M.; Carnio, D.; Cesàro, A. Thermal behavior of water in micro-particles based on alginate gel J. Therm. Anal. Calorim. 2009, 97, 871
5. Daniel, C.; Alfano, D.; Venditto, V.; Cardea, S.; Reverchon, E.; Larobina, D.; Mensitieri, G.; Guerra, G. Aerogels with a microporous crystalline host phase Adv. Mater. 2005, 17 (12) 1515
6. Reverchon, E.; Pisanti, P.; Cardea, S. Nanostructured PLLA-hydroxyapatite scaffolds produced by a supercritical assisted technique Ind. Eng. Chem. Res. 2009, 48 (11) 5310
7. 2 assisted formation of poly(vinylidenefluoride) aerogels containing amoxicillin as controlled release device J. Supercrit. Fluids 2011, 59, 149
8. Caputo, G.; De Marco, I.; Reverchon, E. Silica aerogel-metal composites produced by supercritical adsorption J. Supercrit. Fluids 2010, 54 (2) 243
9. Reverchon, E.; Adami, R.; Cardea, S.; Della Porta, G. Supercritical fluids processing of polymers for pharmaceutical and medical applications J. Supercrit. Fluids 2009, 47, 484
10. Cardea, S.; Pisanti, P.; Reverchon, E. Generation of chitosan nanoporous structures for tissue engineering applications using a supercritical fluid assisted process J. Supercrit. Fluids 2010, 54, 290
11. Della Porta, G.; Reverchon, E. Continuous supercritical emulsions extraction: A new technology for biopolymer microparticles production Biotechnol. Bioeng. J. 2011, 108 (3) 676
12. Falco, N.; Reverchon, E.; Della Porta, G. Continuous supercritical emulsions extraction: Packed tower characterization and application to poly(lactic-co-glycolic acid) plus insulin microspheres production Ind. Eng. Chem. Res. 2012, 51, 8616
13. Campardelli, R.; Adami, R.; Della Porta, G.; Reverchon, E. Nanoparticle precipitation by supercritical assisted injection in a liquid antisolvent Chem. Eng. J. 2012, 192, 246
14. 4 microparticles for biomedical applications produced by supercritical assisted atomization Powder Technol. 2012, 218, 102
15. Reverchon, E.; Caputo, G.; Correra, S.; Cesti, P. Synthesis of titanium hydroxide nanoparticles in supercritical carbon dioxide on the pilot scale J. Supercrit. Fluids 2003, 26 (3) 253
16. George, M.; Abraham, T. E. Polyionic hydrocolloids for the intestinal delivery of protein drugs: Alginate and chitosan-A review J. Controlled Release 2006, 114, 1
17. Thu, B.; Bruheim, P.; Espevik, T.; Smidsrød, O.; Soon-Shiong, P.; Skjåk-Bræk, G. Alginate polycation microcapsules: I. Interaction between alginate and polycation Biomaterials 1996, 17, 1031
18. Zheng, H. Interaction mechanism in sol-gel transition of alginate solutions by addition of divalent cations Carbohydr. Res. 1997, 302, 97
19. Benoit, J. P.; Faisant, N.; Venier-Julienne, M. C.; Menei, P. Development of microspheres for neurological disorders: From basics to clinical applications J. Controlled Release 2000, 65, 285
20. Del Gaudio, P.; Russo, P.; Lauro, M. R.; Colombo, P.; Aquino, R. P. Encapsulation of ketoprofen and ketoprofen lysinate by prilling for controlled drug release AAPS PharmSciTech 2009, 10, 1178
21. Chayosumrit, M.; Tuch, B.; Sidhu, K. Alginate microcapsule for propagation and directed differentiation of hescs to definitive endoderm Biomaterials 2010, 31, 505
22. George, M.; Abraham, T. E. pH sensitive alginate-guar gum hydrogel for the controlled delivery of protein drugs Int. J. Pharm. 2007, 335, 123
23. Gong, R.; Li, C.; Zhu, S.; Zhang, Y.; Du, Y.; Jiang, J. A novel pH-sensitive hydrogel based on dual crosslinked alginate/N-[alpha]-glutaric acid chitosan for oral delivery of protein Carbohydr. Polym. 2011, 85, 869
24. Brandenberg, H.; Widmer, F. A new multinozzle encapsulation/ immobilization system to produce uniform beads of alginate J. Biotechnol. 1998, 63, 73
25. Aquino, R. P.; Auriemma, G.; D'Amore, M.; D'Ursi, A. M.; Mencherini, T.; Del Gaudio, P. Piroxicam loaded alginate beads obtained by prilling/microwave tandem technique: Morphology and drug release Carbohydr. Polym. 2012, 89 (3) 740
26. Robitzer, M.; David, L.; Rochas, C.; Di Renzo, F.; Quignard, F. Nanostructure of calcium alginate aerogels obtained from multistep solvent exchange route Langmuir 2008, 24, 12547
27. Quignard, F.; Valentin, R.; Di Renzo, F. Aerogels materials from marine polysaccharides New J. Chem. 2008, 32, 1300
28. Gavillon, R.; Budtova, T. Aerocellulose: New highly porous cellulose prepared from cellulose-NaOH aqueous solutions Biomacromolecules 2008, 9, 269
29. Alnaief, M.; Alzaitoun, M. A.; García-González, C. A.; Smirnova, I. Preparation of biodegradable nanoporous microspherical aerogel based on alginate Carbohydr. Polym. 2011, 84, 1011
30. Alnaief, M.; Smirnova, I. In situ production of spherical aerogel microparticles J. Supercrit. Fluids 2011, 55, 1118
31. Del Gaudio, P.; Auriemma, G.; Mencherini, T.; Della Porta, G.; Reverchon, E.; Aquino, R. P. Design of alginate-based aerogel for nonsteroidal anti-inflammatory drugs controlled delivery systems using prilling and supercritical-assisted drying J. Pharm. Sci. 2013, 102 (1) 185
32. Chiu, H. Y.; Lee, M. J.; Lin, H. Vapor-liquid phase boundaries of binary mixtures of carbon dioxide with ethanol and acetone J. Chem. Eng. 2008, 53, 2393
33. 2 J. Supercrit. Fluids 2003, 27, 73
34. Dusseault, J.; Tam, S. K.; Ménard, M.; Polizu, S.; Jourdan, G.; Yahia, L.; Hallé, J. Evaluation of alginate purification methods: Effect on polyphenol, endotoxin, and protein contamination J. Biomed. Mater. Res., Part A 2006, 76, 243
35. Laudani, C. G.; Habulin, M.; Knez, Z.; Della Porta, G.; Reverchon, E. Lipase-catalyzed long chain fatty ester synthesis in dense carbon dioxide: Kinetics and thermodynamics J. Supercrit. Fluids 2007, 41 (1) 92
36. Durling, N. E.; Catchpole, O. J.; Tallon, S. J.; Grey, J. B. Measurement and modelling of the ternary phase equilibria for high pressure carbon dioxide-ethanol-water mixtures Fluid Phase Equilib. 2007, 252, 103