메뉴 건너뛰기




Volumn 51, Issue 25, 2012, Pages 8616-8623

Continuous supercritical emulsions extraction: Packed tower characterization and application to poly(lactic-co-glycolic Acid) + insulin microspheres production

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE PRINCIPLES; CONTINUOUS EXTRACTION; CONTINUOUS OPERATION; COUNTER CURRENT; DENSITY DIFFERENCE; DOUBLE EMULSIONS; ENCAPSULATION EFFICIENCY; ETHYL ACETATES; EXPERIMENTAL DATA; MEAN DIAMETER; MICRO DEVICES; PACKED TOWER; PARTICLE MORPHOLOGIES; POLY LACTIC-CO-GLYCOLIC ACID; SOLVENT RESIDUES; SUPER-CRITICAL; WATER SUSPENSIONS;

EID: 84863213455     PISSN: 08885885     EISSN: 15205045     Source Type: Journal    
DOI: 10.1021/ie300482n     Document Type: Article
Times cited : (38)

References (36)
  • 1
    • 0029335538 scopus 로고
    • Biodegradable polymers for protein and peptide drug delivery
    • Gombotz, W. R.; Pettit, D. K. Biodegradable polymers for protein and peptide drug delivery Bioconjugate Chem. 1995, 6 (4) 332-351
    • (1995) Bioconjugate Chem. , vol.6 , Issue.4 , pp. 332-351
    • Gombotz, W.R.1    Pettit, D.K.2
  • 2
    • 0027590742 scopus 로고
    • The pharmaceutics and delivery of therapeutic polypeptides and proteins
    • Talmadse, J. E. The pharmaceutics and delivery of therapeutic polypeptides and proteins Adv. Drug Delivery Rev. 1993, 10 (2-3) 247-299
    • (1993) Adv. Drug Delivery Rev. , vol.10 , Issue.2-3 , pp. 247-299
    • Talmadse, J.E.1
  • 3
    • 0034601882 scopus 로고    scopus 로고
    • Effect of preparation temperature on the characteristics and release profiles of PLGA microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method
    • Yang, Y. Y.; Chia, H. H.; Chung, T. S. Effect of preparation temperature on the characteristics and release profiles of PLGA microspheres containing protein fabricated by double-emulsion solvent extraction/evaporation method J. Controlled Release 2000, 69 (1) 81-96
    • (2000) J. Controlled Release , vol.69 , Issue.1 , pp. 81-96
    • Yang, Y.Y.1    Chia, H.H.2    Chung, T.S.3
  • 4
    • 11844259383 scopus 로고    scopus 로고
    • Microencapsulation by solvent extraction/evaporation: Reviewing the state of the art of microsphere preparation process technology
    • Freitas, S.; Merkle, H. P.; Gander, B. Microencapsulation by solvent extraction/evaporation: Reviewing the state of the art of microsphere preparation process technology J. Controlled Release 2005, 102 (2) 313-332
    • (2005) J. Controlled Release , vol.102 , Issue.2 , pp. 313-332
    • Freitas, S.1    Merkle, H.P.2    Gander, B.3
  • 5
    • 0032078388 scopus 로고    scopus 로고
    • Recombinant human erythropoietin (rhEPO) loaded poly(lactide-co- glycolide) microspheres: Influence of the encapsulation technique and polymer purity on microsphere characteristics
    • Bittner, B.; Morlock, M.; Koll, H.; Winter, G.; Kissel, T. Recombinant human erythropoietin (rhEPO) loaded poly(lactide-co-glycolide) microspheres: Influence of the encapsulation technique and polymer purity on microsphere characteristics Eur. J. Pharm. Biopharm. 1998, 45 (3) 295-305
    • (1998) Eur. J. Pharm. Biopharm. , vol.45 , Issue.3 , pp. 295-305
    • Bittner, B.1    Morlock, M.2    Koll, H.3    Winter, G.4    Kissel, T.5
  • 6
    • 0030575734 scopus 로고    scopus 로고
    • Influence of temperature and shaking on stability of insulin preparation: Degradation kinetics
    • Oliva, A.; Faría, J. B; Labrés, M. Influence of temperature and shaking on stability of insulin preparation: degradation kinetics Int. J. Pharm. 1996, 143 (2) 163-170
    • (1996) Int. J. Pharm. , vol.143 , Issue.2 , pp. 163-170
    • Oliva, A.1    Faría, J.B.2    Labrés, M.3
  • 8
    • 33645342481 scopus 로고    scopus 로고
    • Drug encapsulation using supercritical fluid extraction of emulsions
    • Chattopadhyay, P.; Huff, R.; Shekunov, B. Y. Drug encapsulation using supercritical fluid extraction of emulsions J. Pharm. Sci. 2006, 95 (3) 667-679
    • (2006) J. Pharm. Sci. , vol.95 , Issue.3 , pp. 667-679
    • Chattopadhyay, P.1    Huff, R.2    Shekunov, B.Y.3
  • 9
    • 34547905415 scopus 로고    scopus 로고
    • Production of solid lipid nanoparticle suspensions using supercritical fluid extraction of emulsions (SFEE) for pulmonary delivery using the AERx system
    • Chattopadhyay, P.; Shekunov, B. Y.; Yim, D.; Cipolla, D.; Boyd, B.; Farr, S. Production of solid lipid nanoparticle suspensions using supercritical fluid extraction of emulsions (SFEE) for pulmonary delivery using the AERx system Adv. Drug Delivery Rev. 2007, 59 (6) 444-453
    • (2007) Adv. Drug Delivery Rev. , vol.59 , Issue.6 , pp. 444-453
    • Chattopadhyay, P.1    Shekunov, B.Y.2    Yim, D.3    Cipolla, D.4    Boyd, B.5    Farr, S.6
  • 10
    • 48449092208 scopus 로고    scopus 로고
    • Nanostructured microspheres produced by supercritical fluid extraction of emulsion
    • Della Porta, G.; Reverchon, E. Nanostructured microspheres produced by supercritical fluid extraction of emulsion Biotechnol. Bioeng. 2008, 100 (5) 1020-1033
    • (2008) Biotechnol. Bioeng. , vol.100 , Issue.5 , pp. 1020-1033
    • Della Porta, G.1    Reverchon, E.2
  • 11
    • 76649091559 scopus 로고    scopus 로고
    • NSAID Drugs release from injectable microspheres produced by Supercritical Fluid Emulsion Extraction
    • Della Porta, G.; Falco, N.; Reverchon, E. NSAID Drugs release from injectable microspheres produced by Supercritical Fluid Emulsion Extraction J. Pharm. Sci. 2010, 99 (3) 1484-1489
    • (2010) J. Pharm. Sci. , vol.99 , Issue.3 , pp. 1484-1489
    • Della Porta, G.1    Falco, N.2    Reverchon, E.3
  • 12
    • 78751538648 scopus 로고    scopus 로고
    • Continuous Supercritical Emulsions Extraction: A new technology for biopolymer microparticles production
    • Della Porta, G.; Falco, N.; Reverchon, E. Continuous Supercritical Emulsions Extraction: a new technology for biopolymer microparticles production Biotechnol. Bioeng. 2011, 108 (3) 676-677
    • (2011) Biotechnol. Bioeng. , vol.108 , Issue.3 , pp. 676-677
    • Della Porta, G.1    Falco, N.2    Reverchon, E.3
  • 13
    • 80052265512 scopus 로고    scopus 로고
    • PLGA microdevices for retinoids sustained release produced by Supercritical Emulsion Extraction: Continuous versus batch operation layouts
    • Della Porta, G.; Campardelli, R.; Falco, N.; Reverchon, E. PLGA microdevices for retinoids sustained release produced by Supercritical Emulsion Extraction: continuous versus batch operation layouts J. Pharm. Sci. 2011, 100 (10) 4357-4367
    • (2011) J. Pharm. Sci. , vol.100 , Issue.10 , pp. 4357-4367
    • Della Porta, G.1    Campardelli, R.2    Falco, N.3    Reverchon, E.4
  • 14
    • 0033956526 scopus 로고    scopus 로고
    • Biomaterials in drug delivery and tissue engineering: One laboratory's experience
    • Langer, R. Biomaterials in drug delivery and tissue engineering: one laboratory's experience Acc. Chem. Res. 2000, 33 (2) 94-101
    • (2000) Acc. Chem. Res. , vol.33 , Issue.2 , pp. 94-101
    • Langer, R.1
  • 15
    • 27744496506 scopus 로고    scopus 로고
    • Preparation, in vitro release, in vivo absorption and biocompatibility studies of insulin-loaded microspheres in rabbits
    • Kang, F.; Singh, J. Preparation, in vitro release, in vivo absorption and biocompatibility studies of insulin-loaded microspheres in rabbits AAPS PharmSciTech 2005, 6 (3) E487-494
    • (2005) AAPS PharmSciTech , vol.6 , Issue.3 , pp. 487-494
    • Kang, F.1    Singh, J.2
  • 16
    • 11944260300 scopus 로고    scopus 로고
    • In vivo and in vitro characteristics for insulin-loaded PLA microparticles prepared by w/o/w solvent evaporation method with electrolytes in the continuous phase
    • Yeh, M. K.; Chen, J. L.; Chiang, C. H. In vivo and in vitro characteristics for insulin-loaded PLA microparticles prepared by w/o/w solvent evaporation method with electrolytes in the continuous phase J. Microencapsulation 2004, 21 (7) 719-728
    • (2004) J. Microencapsulation , vol.21 , Issue.7 , pp. 719-728
    • Yeh, M.K.1    Chen, J.L.2    Chiang, C.H.3
  • 17
    • 33749037141 scopus 로고    scopus 로고
    • PLGA microspheres with high drug loading and high encapsulation efficiency prepared by a novel solvent evaporation technique
    • Bao, W.; Zhou, J.; Luo, J.; Wu, D. PLGA microspheres with high drug loading and high encapsulation efficiency prepared by a novel solvent evaporation technique J. Microencapsulation 2006, 23 (5) 471-479
    • (2006) J. Microencapsulation , vol.23 , Issue.5 , pp. 471-479
    • Bao, W.1    Zhou, J.2    Luo, J.3    Wu, D.4
  • 18
  • 20
    • 33645512835 scopus 로고    scopus 로고
    • Nanoprecipitation versus emulsion-based techniques for the encapsulation of proteins into biodegradable nanoparticles and process-related stability issues
    • Bilati, U.; Allémann, E.; Doelker, E. Nanoprecipitation versus emulsion-based techniques for the encapsulation of proteins into biodegradable nanoparticles and process-related stability issues AAPS PharmSciTech 2005, 6 (4) E594-604
    • (2005) AAPS PharmSciTech , vol.6 , Issue.4 , pp. 594-604
    • Bilati, U.1    Allémann, E.2    Doelker, E.3
  • 22
    • 58149343262 scopus 로고    scopus 로고
    • Counter-current separations
    • Brunner, G. Counter-current separations J. Supercrit. Fluids 2009, 47 (3) 574-582
    • (2009) J. Supercrit. Fluids , vol.47 , Issue.3 , pp. 574-582
    • Brunner, G.1
  • 25
    • 0034728286 scopus 로고    scopus 로고
    • Separation of fish oil ethyl esters with supercritical carbon dioxide
    • Riha, V.; Brunner, G. Separation of fish oil ethyl esters with supercritical carbon dioxide J. Supercrit. Fluids 2000, 17 (1) 55-64
    • (2000) J. Supercrit. Fluids , vol.17 , Issue.1 , pp. 55-64
    • Riha, V.1    Brunner, G.2
  • 26
    • 20044381792 scopus 로고    scopus 로고
    • Particle size and temperature effect on the physical stability of PLGA nano-spheres and micro-spheres containing Bodipy
    • De, S.; Robinson, D. H. Particle size and temperature effect on the physical stability of PLGA nano-spheres and micro-spheres containing Bodipy AAPS PharmSciTech 2004, 5 (4) 18-24
    • (2004) AAPS PharmSciTech , vol.5 , Issue.4 , pp. 18-24
    • De, S.1    Robinson, D.H.2
  • 28
    • 1842685980 scopus 로고    scopus 로고
    • Solubility of water in supercritical carbon dioxide
    • Sabirzyanov, A. N.; Il'in, A. P.; Akhunov, A. R.; Gumerov, F. M. Solubility of water in supercritical carbon dioxide High Temp. 2002, 40 (2) 203-206
    • (2002) High Temp. , vol.40 , Issue.2 , pp. 203-206
    • Sabirzyanov, A.N.1    Ilin, A.P.2    Akhunov, A.R.3    Gumerov, F.M.4
  • 29
    • 0034609628 scopus 로고    scopus 로고
    • Development and in vitro characterization of vascular endothelial growth factor (VEGF)-loaded poly(lactic-co-glycolic acid)/poly(ethylene glycol) microspheres using a solid encapsulation/single emulsion/solvent extraction technique
    • King, T. W.; Patrick, C. W. Development and in vitro characterization of vascular endothelial growth factor (VEGF)-loaded poly(lactic-co-glycolic acid)/poly(ethylene glycol) microspheres using a solid encapsulation/single emulsion/solvent extraction technique J. Biomed. Mater. Res. 2000, 51 (3) 383-390
    • (2000) J. Biomed. Mater. Res. , vol.51 , Issue.3 , pp. 383-390
    • King, T.W.1    Patrick, C.W.2
  • 30
    • 0001621707 scopus 로고
    • The solubility of carbon dioxide in water at various temperatures from 12 to 40°C and at pressures to 500 atm. Critical phenomena
    • Wiebe, R.; Gaddy, V. The solubility of carbon dioxide in water at various temperatures from 12 to 40°C and at pressures to 500 atm. Critical phenomena J. Am. Chem. Soc. 1940, 62 (4) 815-817
    • (1940) J. Am. Chem. Soc. , vol.62 , Issue.4 , pp. 815-817
    • Wiebe, R.1    Gaddy, V.2
  • 31
    • 67749133382 scopus 로고    scopus 로고
    • Production of PLGA micro- and nanocomposites by supercritical fluid extraction of emulsions: I. Encapsulation of lysozyme
    • Kluge, J.; Fusaro, F.; Casas, N.; Mazzotti, M.; Muhrer, G. Production of PLGA micro- and nanocomposites by supercritical fluid extraction of emulsions: I. Encapsulation of lysozyme J. Supercrit. Fluids 2009, 50 (3) 327-335
    • (2009) J. Supercrit. Fluids , vol.50 , Issue.3 , pp. 327-335
    • Kluge, J.1    Fusaro, F.2    Casas, N.3    Mazzotti, M.4    Muhrer, G.5
  • 32
    • 0037124470 scopus 로고    scopus 로고
    • Insulin-loaded biodegradable PLGA microcapsules: Initial burst release controlled by hydrophilic additives
    • Yamaguchi, Y.; Takenaga, M.; Kitagawa, A.; Ogawa, Y.; Mizushima, Y.; Igarashi, R. Insulin-loaded biodegradable PLGA microcapsules: initial burst release controlled by hydrophilic additives J. Controlled Release 2002, 81 (3) 235-249
    • (2002) J. Controlled Release , vol.81 , Issue.3 , pp. 235-249
    • Yamaguchi, Y.1    Takenaga, M.2    Kitagawa, A.3    Ogawa, Y.4    Mizushima, Y.5    Igarashi, R.6
  • 33
    • 33746197968 scopus 로고    scopus 로고
    • Preparation of insulin-loaded PLA/PLGA microcapsules by a novel membrane emulsification method and its release in vitro
    • Liu, R.; Huang, S. S.; Wan, Y. H.; Ma, G. H.; Su, Z. G. Preparation of insulin-loaded PLA/PLGA microcapsules by a novel membrane emulsification method and its release in vitro Coll. Surf., B: Biointerfaces 2006, 51 (1) 30-38
    • (2006) Coll. Surf., B: Biointerfaces , vol.51 , Issue.1 , pp. 30-38
    • Liu, R.1    Huang, S.S.2    Wan, Y.H.3    Ma, G.H.4    Su, Z.G.5
  • 34
    • 0030955276 scopus 로고    scopus 로고
    • Preparation and characterization of polylactic acid microspheres containing bovine insulin by a w/o/w emulsion solvent evaporation method
    • Uchida, T.; Nagareya, N.; Sakakibara, S.; Konishi, Y.; Nakai, A.; Nishikata, M.; Matsuyama, K.; Yoshida, K. Preparation and characterization of polylactic acid microspheres containing bovine insulin by a w/o/w emulsion solvent evaporation method Chem. Pharm. Bull. (Tokyo) 1997, 45 (9) 1539-1543
    • (1997) Chem. Pharm. Bull. (Tokyo) , vol.45 , Issue.9 , pp. 1539-1543
    • Uchida, T.1    Nagareya, N.2    Sakakibara, S.3    Konishi, Y.4    Nakai, A.5    Nishikata, M.6    Matsuyama, K.7    Yoshida, K.8
  • 35
    • 0033979387 scopus 로고    scopus 로고
    • Porcine insulin biodegradable polyester microspheres: Stability and in vitro release characteristics
    • Shao, P. G.; Bailey, L. C. Porcine insulin biodegradable polyester microspheres: stability and in vitro release characteristics Pharm. Dev. Technol. 2000, 5 (1) 1-9
    • (2000) Pharm. Dev. Technol. , vol.5 , Issue.1 , pp. 1-9
    • Shao, P.G.1    Bailey, L.C.2
  • 36
    • 0032863681 scopus 로고    scopus 로고
    • Pulmonary delivery of insulin with nebulized DL-lactide/glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect
    • Kawashima, Y.; Yamamoto, H.; Takeuchi, H.; Fujioka, S.; Hino, T. Pulmonary delivery of insulin with nebulized DL-lactide/glycolide copolymer (PLGA) nanospheres to prolong hypoglycemic effect J. Controlled Release 1999, 62 (1-2) 279-287
    • (1999) J. Controlled Release , vol.62 , Issue.1-2 , pp. 279-287
    • Kawashima, Y.1    Yamamoto, H.2    Takeuchi, H.3    Fujioka, S.4    Hino, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.