Composite polymer-Fe 3O 4 microparticles for biomedical applications, produced by Supercritical Assisted Atomization

Powder Technology

Volumn 218, Issue , 2012, Pages 102-108

  Adami, Renata ^a   Reverchon, Ernesto ^a  

^a UNIVERSITY OF SALERNO   (Italy)

Author keywords

Atomization; Magnetic; Microparticles; Nanoparticles; Supercritical

Indexed keywords

BIOMEDICAL APPLICATIONS; CHITOSAN MICROSPHERES; COMPOSITE MICROPARTICLES; ENERGY DISPERSIVE X-RAY; MAGNETIC; MAGNETITE NANOPARTICLES; MATRIX; MEAN DIAMETER; MICRO-PARTICLES; MICRONIZATIONS; MULTICOMPONENTS; NANO-PARTICLE DISPERSIONS; NANO-STRUCTURED; NANOPARTICLE LOADINGS; POLYMER MICROPARTICLES; POLYMER-SOLVENT SOLUTIONS; POLYMERIC COATINGS; POLYMERIC MATRICES; SCANNING ELECTRON MICROSCOPE; STERIC BARRIER; SUPER-CRITICAL; SUPERCRITICAL ASSISTED ATOMIZATION; WORKING PRINCIPLES;

ATOMIZATION; CHITOSAN; DISPERSIONS; EFFLUENT TREATMENT; MEDICAL APPLICATIONS; NANOPARTICLES; PARTICLE SIZE ANALYSIS; PLASTIC COATINGS; SCANNING ELECTRON MICROSCOPY; SUPERCRITICAL FLUIDS; THERMOGRAVIMETRIC ANALYSIS;

FUNCTIONAL POLYMERS;

MAGNETITE NANOPARTICLE;

ANALYTIC METHOD; ARTICLE; CONCENTRATION (PARAMETERS); MATERIAL COATING; MICROENCAPSULATION; MOLECULAR STABILITY; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; STRUCTURE ANALYSIS; SUPERCRITICAL ASSISTED ATOMIZATION; SUPERCRITICAL FLUID; THERMOGRAVIMETRY;

EID: 84855830101     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2011.11.048     Document Type: Article

References (27)

1. Magnetic Nanoparticles and Their Application in Biomedicine. Satnos, SP, Brazil 2007, M.C.F.C. Felinto, R.L. Camilo, T.G. Diegues (Eds.).
2. Boehm F.J., Chen A. Medical applications of hyperthermia based on magnetic nanoparticles. Recent Patents on Biomedical Engineering 2009, 2(2):110-120.
3. Hergt R., Dutz S., Muller R., Zeisberger M. Magnetic particle hyperthermia: nanoparticle magnetism and materials development for cancer therapy. Journal of Physics Condensed Matter: an Institute of Physics journal 2006 Sep 27, 18(38):S2919-S2934.
4. Moroz P., Jones S.K., Gray B.N. Magnetically mediated hyperthermia: current status and future directions. International journal of hyperthermia: the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 2002 Jul, 18(4):267-284.
5. Neuberger T., Schopf B., Hofmann H., Hofmann M., von Rechenberg B. Superparamagnetic nanoparticles for biomedical applications: possibilities and limitations of a new drug delivery system. Journal of Magnetism and Magnetic Materials 2005 May 1, 293(1):483-496.
6. 2. Journal of Colloid and Interface Science 2009 Feb 15, 330(2):317-322.
7. Fang C., Zhang M. Multifunctional magnetic nanoparticles for medical imaging applications. Journal of Materials Chemistry 2009 Jan 1, 19:6258-6266.
8. Liu X.Q., Kaminski M.D., Riffle J.S., Chen H.T., Torno M., Finck M.R., et al. Preparation and characterization of biodegradable magnetic carriers by single emulsion-solvent evaporation. Journal of Magnetism and Magnetic Materials 2007 Apr, 311(1):84-87.
9. Liu Z.L., Liu C.C., Yao K.L., Liu P.D., Ning Q. Preparation and characterization of micron-sized magnetic microspheres by one-step suspension polymerization. Journal of Applied Polymer Science 2007 Aug 5, 105(3):1331-1335.
10. Shpaisman N., Margel S. Synthesis and characterization of air-stable magnetic Fe composites microspheres of narrow size distribution. Journal of Applied Polymer Science 2008 Feb 5, 107(3):1710-1717.
11. Dos Santos I.R., Richard J., Pech B., Thies C., Benoit J.P. Microencapsulation of protein particles within lipids using a novel supercritical fluid process. International Journal of Pharmaceutics 2002 Aug 21, 242(1-2):69-78.
12. Bleich J., Muller B.W. Production of drug loaded microparticles by the use of supercritical gases with the aerosol solvent extraction system (ASES) process. Journal of Microencapsulation 1996 Mar-Apr, 13(2):131-139.
13. Debenedetti P.G., Tom J.W., Yeo S.D., Lim G.B. Application of supercritical fluids for the production of sustained delivery devices. Journal of Controlled Release 1993, 24(1-3):27-44.
14. Della Porta G., Adami R., Del Gaudio P., Prota L., Aquino R., Reverchon E. Albumin/gentamicin microspheres produced by supercritical assisted atomization: optimization of size, drug loading and release. Journal of Pharmaceutical Sciences 2010, 99(11):4720-4729.
15. Reverchon E., Antonacci A. Drug-polymer microparticles produced by supercritical assisted atomization. Biotechnology and Bioengineering 2007, 97(6):1626-1637.
16. Vezzù K., Borin D., Bertucco A., Bersani S., Salmaso S., Caliceti P. Production of lipid microparticles containing bioactive molecules functionalized with PEG. Journal of Supercritical Fluids 2010, 54(3):328-334.
17. Furlan M., Kluge J., Mazzotti M., Lattuada M. Preparation of biocompatible magnetite-PLGA composite nanoparticles using supercritical fluid extraction of emulsions. Journal of Supercritical Fluids 2010 Sep, 54(3):348-356.
18. Reverchon E. Supercritical-assisted atomization to produce micro- and/or nanoparticles of controlled size and distribution. Industrial and Engineering Chemistry Research 2002, 41(10):2405-2411.
19. Caputo G., Adami R., Reverchon E. Analysis of dissolved-gas atomization: supercritical CO(2) dissolved in water. Industrial and Engineering Chemistry Research 2010, 49(19):9454-9461.
20. Reverchon E., Antonacci A. Polymer microparticles production by supercritical assisted atomization. Journal of Supercritical Fluids 2007, 39(3):444-452.
21. Reverchon E., Antonacci A. Chitosan microparticles production by supercritical fluid processing. Industrial and Engineering Chemistry Research 2006, 45(16):5722-5728.
22. Reverchon E., Adami R., Cardea S., Della Porta G. Supercritical fluids processing of polymers for pharmaceutical and medical applications. Journal of Supercritical Fluids 2009, 47(3):484-492.
23. Adami R., Osseo L.S., Reverchon E. Micronization of lysozyme by supercritical assisted atomization. Biotechnology and Bioengineering 2009, 104(6):1162-1170.
24. Reverchon E., Adami R., Caputo G. Production of cromolyn sodium microparticles for aerosol delivery by supercritical assisted atomization. AAPS PharmSciTech 2007, 8(4).
25. Della Porta G., De Vittori C., Reverchon E. Supercritical assisted atomization: a novel technology for microparticles preparation of an asthma-controlling drug. AAPS PharmSciTech 2005, 6(3).
26. Reverchon E., Della Porta G. Terbutaline microparticles suitable for aerosol delivery produced by supercritical assisted atomization. International Journal of Pharmaceutics 2003, 258(1-2):1-9.
27. Reverchon E., Lamberti G., Antonacci A. Supercritical fluid assisted production of HPMC composite microparticles. Journal of Supercritical Fluids 2008, 46(2):185-196.