Determination of the effects of lactoferrin in a preclinical mouse model of experimental colitis

Molecular Medicine Reports

Volumn 8, Issue 4, 2013, Pages 1125-1129

  Li, Li ^a,b   Ren, Fazheng ^b   Yun, Zhanyou ^a   An, Ying ^a   Wang, Caiyun ^a   Yan, Xudong ^a  

^a Technology Center Inner Mongolia Yili Industrial Group Co Ltd   (China)

^b CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

Dextran sulphate sodium (DSS); Experimentally induced colitis; Interleukin 1 ; Lactoferrin; Myeloperoxidase; Tumor necrosis factor

Indexed keywords

DEXTRAN SULFATE; INTERLEUKIN 1BETA; LACTOFERRIN; MYELOPEROXIDASE; TUMOR NECROSIS FACTOR ALPHA; ANTIINFLAMMATORY AGENT; INTERLEUKIN-1BETA (163-171); PEPTIDE FRAGMENT; PEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COLITIS; CONTROLLED STUDY; DISEASE ACTIVITY; DRUG EFFICACY; DRUG SCREENING; ENZYME ACTIVITY; HISTOLOGY; INFLAMMATION; MALE; MOUSE; NONHUMAN; OCCULT BLOOD; PROTEIN EXPRESSION; RECTUM HEMORRHAGE; WEIGHT REDUCTION; ANIMAL; BAGG ALBINO MOUSE; CHEMICALLY INDUCED; COLITIS, ULCERATIVE; COLON; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION; GENETICS; METABOLISM; PATHOLOGY;

MUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; COLITIS, ULCERATIVE; COLON; DEXTRAN SULFATE; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION; INTERLEUKIN-1BETA; LACTOFERRIN; MALE; MICE; MICE, INBRED BALB C; PEPTIDE FRAGMENTS; PEROXIDASE;

EID: 84883386698     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1632     Document Type: Article

References (21)

1. Legrand D, Elass E, Carpentier M and Mazurier J: Lactoferrin: a modulator of immune and inflammatory responses. Cell Mol Life Sci 62: 2549-2559, 2005.
2. Valenti P and Antonini G: Lactoferrin: an important host defence against microbial and viral attack. Cell Mol Life Sci 62: 2576-2587, 2005.
3. Mogensen SC and Virelizier JL: The interferon-macrophage alliance. Interferon 8: 55-84, 1987.
4. Jiang XL and Cui HF: An analysis of 10218 ulcerative colitis cases in China. World J Gastroenterol 8: 158-161, 2002.
5. Carvalho R and Hyams JS: Diagnosis and management of inflammatory bowel disease in children. Semin Pediatr Surg 16: 164-171, 2007.
6. Shanahan F: Crohn's disease. Lancet 359: 62-69, 2002.
7. Togawa J, Nagase H, Tanaka K, et al: Lactoferrin reduces colitis in rats via modulation of the immune system and correction of cytokine imbalance. Am J Physiol Gastrointest Liver Physiol 283: G187-G195, 2002.
8. Lu RR: Isolation, purification and bioactive functions of lactoferrin (unpublished PhD thesis). Jiangnan University, 2003 (In Chinese).
9. Hamamoto N, Maemura K, Hirata I, Murano M, Sasaki S and Katsu K: Inhibition of dextran sulphate sodium (DSS)-induced colitis in mice by intracolonically administered antibodies against adhesion molecules (endothelial leucocyte adhesion molecule-1 (ELAM-1) or intercellular adhesion molecule-1 (ICAM-1)). Clin Exp Immunol 117: 462-468, 1999.
10. Cooper HS, Murthy SN, Shah RS and Sedergran DJ: Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 69: 238-249, 1993.
11. Fabia R, Ar'Rajab A, Johansson ML, et al: The effect of exogenous administration of Lactobacillus reuteri R2LC and oat fiber on acetic acid-induced colitis in the rat. Scand J Gastroenterol 28: 155-162, 1993.
12. Egger B, Bajaj-Elliott M, MacDonald TT, Inglin R, Eysselein VE and Büchler MW: Characterisation of acute murine dextran sodium sulphate colitis: cytokine profile and dose dependency. Digestion 62: 240-248, 2000.
13. Zhang SZ, Zhao XH and Zhang DC: Cellular and molecular immunopathogenesis of ulcerative colitis. Cell Mol Immunol 3: 35-40, 2006.
14. Yan Y, Kolachala V, Dalmasso G, et al: Temporal and spatial analysis of clinical and molecular parameters in dextran sodium sulfate induced colitis. PLoS One 4: e6073, 2009.
15. Beagley KW and Elson CO: Cells and cytokines in mucosal immunity and inflammation. Gastroenterol Clin North Am 21: 347-366, 1992.
16. Ishiguro Y: Mucosal proinflammatory cytokine production correlates with endoscopic activity of ulcerative colitis. J Gastroenterol 34: 66-74, 1999.
17. Wang QY, Chen CL, Wang JD, Lai ZS, Ma Q and Zhang YL: Expression of pro-inflammation cytokines and activation of nuclear factor kappab in the intestinal mucosa of mice with ulcerative colitis. Di Yi Jun Yi Da Xue Xue Bao 23: 1202-1205, 2003 (In Chinese).
18. Rachmilewitz D, Karmeli F, Shteingart S, Lee J, Takabayashi K and Raz E: Immunostimulatory oligonucleotides inhibit colonic proinflammatory cytokine production in ulcerative colitis. Inflamm Bowel Dis 12: 339-345, 2006.
19. Kim WS, Tanaka T, Kumura H and Shimazaki K: Lactoferrin-binding proteins in Bifidobacterium bifidum. Biochem Cell Biol 80: 91-94, 2002.
20. Tomita M, Wakabayashi H, Yamauchi K, Teraguchi S and Hayasawa H: Bovine lactoferrin and lactoferricin derived from milk: production and applications. Biochem Cell Biol 80: 109-112, 2002.
21. Cheng XY and Zhang LL: The relation of fulminant hepatitis with Endotoxin and its receptors and inflammatory cytokines. Jiangxi Medical Journal 41: 114-117, 2006 (In Chinese).