Formation of assemblies on cell membranes by secreted proteins: Molecular studies of free λ light chain aggregates found on the surface of myeloma cells

Biochemical Journal

Volumn 454, Issue 3, 2013, Pages 479-489

  Hutchinson, Andrew T ^a,b   Malik, Ansha ^a   Berkahn, Mark B ^a   Agostino, Mark ^c,d   To, Joyce ^a   Tacchi, Jessica L ^b   Djordjevic, Steven P ^b   Turnbull, Lynne ^b   Whitchurch, Cynthia B ^b   Edmundson, Allen B ^e   Jones, Darren R ^a   Raison, Robert L ^a   Ramsland, Paul A ^c,d,f,g  

^a UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^b UNIVERSITY OF TECHNOLOGY SYDNEY   (Australia)

^c BURNET INSTITUTE   (Australia)

^d CURTIN UNIVERSITY   (Australia)

^e OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^f MONASH UNIVERSITY   (Australia)

^g UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Free immunoglobulin light chain; Membrane protein; Multiple myeloma; Protein aggregation

Indexed keywords

IMMUNOGLOBULIN LIGHT CHAIN; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; PHOSPHOLIPID;

ARTICLE; ATOMIC FORCE MICROSCOPY; CELL MEMBRANE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MOLECULAR DOCKING; MULTIPLE MYELOMA; MYELOMA CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY;

BINDING SITES; CELL LINE, TUMOR; CELL MEMBRANE; HUMANS; IMMUNOGLOBULIN LIGHT CHAINS; MICROSCOPY, ATOMIC FORCE; MOLECULAR DOCKING SIMULATION; MULTIPLE MYELOMA; PHOSPHATIDYLCHOLINES; PROTEIN BINDING;

EID: 84883370837     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20130575     Document Type: Article

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