Autophagy stimulates apoptosis in HER2-overexpressing breast cancers treated by lapatinib

Journal of Cellular Biochemistry

Volumn 114, Issue 12, 2013, Pages 2643-2653

  Zhu, Xingmei ^a   Wu, Lin ^a   Qiao, Hongyu ^a   Han, Tenglong ^a   Chen, Suning ^b   Liu, Xueying ^a   Jiang, Ru ^a   Wei, Yifang ^a   Feng, Dayun ^a   Zhang, Yuan ^a   Ma, Yongzheng ^a   Zhang, Shengyong ^a   Zhang, Jian ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

AMPK; APOPTOSIS; AUTOPHAGY; BREAST CANCER; LAPATINIB; mTOR

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; 3 METHYLADENINE; ACRIDINE ORANGE; ADENYLATE KINASE; CASPASE 3; CELL PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; LAPATINIB; MAMMALIAN TARGET OF RAPAMYCIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN KINASE B; PROTEIN LC3 II; S6 KINASE; UNCLASSIFIED DRUG;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; BREAST CANCER; CONTROLLED STUDY; DNA SYNTHESIS; DRUG TARGETING; ELECTRON MICROSCOPY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

AMPK; APOPTOSIS; AUTOPHAGY; BREAST CANCER; LAPATINIB; MTOR;

ADENINE; APOPTOSIS; AUTOPHAGY; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; QUINAZOLINES; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION;

EID: 84883363937     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.24611     Document Type: Article

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