Secretion of Protective Antigens by Tissue-Stage Nematode Larvae Revealed by Proteomic Analysis and Vaccination-Induced Sterile Immunity

PLoS Pathogens

Volumn 9, Issue 8, 2013, Pages

  Hewitson, James P ^a   Ivens, Al C ^a   Harcus, Yvonne ^a   Filbey, Kara J ^a   McSorley, Henry J ^a   Murray, Janice ^a   Bridgett, Stephen ^a   Ashford, David ^b   Dowle, Adam A ^b   Maizels, Rick M ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF YORK   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINESTERASE; ANTIGEN; APYRASE; PEPTIDES AND PROTEINS; PROTEOME; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VENOM ALLERGEN ANCYLOSTOMA SECRETED PROTEIN LIKE FAMILY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HELIGMOSOMOIDES POLYGYRUS; HOST PARASITE INTERACTION; IMMUNITY; IMMUNOMODULATION; IMMUNOPRECIPITATION; LARVA; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MOUSE; NEMATODE LIFE CYCLE STAGE; NONHUMAN; PHYLOGENY; PROTEOMICS; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS; TWO DIMENSIONAL GEL ELECTROPHORESIS; VACCINATION; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; BLOTTING, WESTERN; CHROMATOGRAPHY, LIQUID; COMPUTATIONAL BIOLOGY; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE EXPRESSION PROFILING; HELMINTH PROTEINS; HOST-PARASITE INTERACTIONS; IMMUNIZATION; IMMUNOPRECIPITATION; LARVA; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; NEMATODE INFECTIONS; NEMATOSPIROIDES DUBIUS; PROTEOMICS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; VACCINATION;

EID: 84883356595     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003492     Document Type: Article

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