Characterization of a cellular denitrase activity that reverses nitration of cyclooxygenase

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 305, Issue 5, 2013, Pages

  Deeb, Ruba S ^a   Nuriel, Tal ^a   Cheung, Cynthia ^a   Summers, Barbara ^a   Lamon, Brian D ^a   Gross, Steven S ^a   Hajjar, David P ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

3 nitrotyrosine; Cyclooxygenase 1; Denitration; HPLC with electrochemical detection; Liquid chromatograph tandem mass spectrometry; Peroxynitrite; Reactive nitrogen species

Indexed keywords

3 NITROTYROSINE; CARBON MONOXIDE; CELL ENZYME; CYCLOOXYGENASE 1; DENITRASE; NITRIC OXIDE; TYROSINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DENITRATION; DISEASE MARKER; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; INFLAMMATION; LIPOGENESIS; MOUSE; NITRATION; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN PROCESSING; PROTEIN PURIFICATION; RAT; SIGNAL TRANSDUCTION;

3-NITROTYROSINE; CYCLOOXYGENASE-1; DENITRATION; HPLC WITH ELECTROCHEMICAL DETECTION; LIQUID CHROMATOGRAPH-TANDEM MASS SPECTROMETRY; PEROXYNITRITE; REACTIVE NITROGEN SPECIES;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CELL LINE; CELLS, CULTURED; CYCLOOXYGENASE 1; ENDOTHELIUM, VASCULAR; HUMANS; MACROPHAGES; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; MUSCLE, SMOOTH, VASCULAR; NITRATES; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDATIVE STRESS; OXIDOREDUCTASES; RATS; TYROSINE;

EID: 84883349829     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00876.2012     Document Type: Article

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