Small proliferative adipocytes: Identification of proliferative cells expressing adipocyte markers

Endocrine Journal

Volumn 60, Issue 8, 2013, Pages 931-939

  Kajita, Kazuo ^a   Mori, Ichiro ^a   Kitada, Yoshihiko ^a   Taguchi, Koichiro ^a   Kajita, Toshiko ^a   Hanamoto, Takayuki ^a   Ikeda, Takahide ^a   Fujioka, Kei ^a   Yamauchi, Masahiro ^a   Okada, Hideyuki ^a   Usui, Taro ^a   Uno, Yoshihiro ^a   Morita, Hiroyuki ^a   Ishizuka, Tatsuo ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Adipocyte; Differentiation; Proliferation

Indexed keywords

ADIPONECTIN; BROXURIDINE; CELL MARKER; CYCLINE; FAT DROPLET; GLUCOSE; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE;

ADIPOCYTE; ADIPOSE TISSUE; CELL DEDIFFERENTIATION; CELL MATURATION; CELL PROLIFERATION; CELL SIZE; CELL STRUCTURE; DRUG MECHANISM; GLUCOSE METABOLISM; HUMAN; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; INSULIN SENSITIVITY; INTRAABDOMINAL FAT; METABOLIC REGULATION; NONHUMAN; OBESITY; PROADIPOCYTE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVIEW; SMALL PROLIFERATIVE ADIPOCYTE; SUBCUTANEOUS FAT; TISSUE SPECIFICITY;

ADIPOCYTES; ADIPOKINES; ANIMALS; BROMODEOXYURIDINE; CELL DEDIFFERENTIATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; HUMANS; IMMUNOHISTOCHEMISTRY; PPAR GAMMA; PROLIFERATING CELL NUCLEAR ANTIGEN; STEM CELLS; THIAZOLIDINEDIONES;

EID: 84883332148     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.EJ13-0141     Document Type: Review

References (33)

1. Goss RJ (1966) Hypertrophy versus hyperplasia. Science 153: 1615-1620.
2. Hirsch J, Han PW (1969) Cellularity of rat adipose tissue: effects of growth, starvation, and obesity. J Lipid Res 10: 77-82.
3. Hirsch J, Gallian E (1968) Methods for the determination of adipose cell size in man and animals. J Lipid Res 9: 110-119.
4. Poznanski WJ, Waheed I, Van R (1973) Human fat cell precursors: Morphological and metabolic differentiation in culture. Lab Invest 29: 570-576.
5. Adebonojo FO (1975) Studies on human adipose cells in culture: Relation of cell size and cell multiplication to donor age. Yale Biol Med 48: 9-16.
6. Hollenberg GH, Vost A (1968) Regulation of DNA synthesis in fat cells and stromal elements from rat adipose tissue. J Clin Invest 47: 2485-2498.
7. Klyde BJ, Hirsch J (1979) Isotopic labeling of DNA in rat adipose tissue: evidence for proliferating cells associated with mature adipocytes. J Lipid Res 20: 691-704.
8. Gaben-Cogneville AM, Swierczewski E (1979) Studies on cell proliferation in inguinal adipose tissue during early development in the rat. Lipid 14: 669-675.
9. Sugihara H, Yonemitsu N, Miyabara S, Toda S (1987) Proliferation of unilocular fat cells in the primary culture. J Lipid Res 28: 1038-1045.
10. Waki H, Tontonoz P (2007) Endocrine function of adipose tissue. Annu Rev Pathol 2: 31-56.
11. Tontonoz P, Spiegelman BM (2008) Fat and beyond: the divers biology of PPAR gamma. Annu Rev Biochem 77: 289-312.
12. Hausman DB, DiGirolamo M, Bartness TJ, Hausman GJ, Martin RJ (2001) The biology of white adipocyte proliferation. Obes Rev 2: 239-254.
13. Zhang B, Berger J, Hu E, Szalkowski D, White Carrington S (1996) Negative regulation of peroxisome proliferator-activated receptor-gamma gene expression contributes to the antiadipogenic effects of tumor necrosis factor-alpha. Mol Endocrinol 10: 1457-1466.
14. Rosen ED, MacDougald OA (2006) Adipocyte differentiation from the inside out. Nat Rev Mol Cell Biol 7: 885-896.
15. Shen J, Sugawara A, Yamashita J, Ogura H, Sato S (2011) Differentiated fat cells: an alternative source of adult multipotent cells from the adipose tissues. Int J Oral Sci 3: 117-124.
16. Matsumoto T, Kano K, Kondo D, Fukuda N, Iribe Y, et al. (2008) Mature adipocyte-derived dedifferentiated fat cells exhibit multilineage potential. J Cell Physiol 215: 210-222.
17. Wei S, Duarte MS, Du M, Paulino PV, Jiang Z, et al. (2012) Bovine mature adipocytes readily return to a proliferative state. Tissue Cell 44: 385-390.
18. Zhang HH, Kumar S, Barnett AH, Eggo MC (2000) Ceiling culture of mature human adipocytes: use in studies of adipocyte function. J Endocrinol 164: 119-128.
19. Yagi K, Kondo D, Okazaki Y, Kano K (2004) A novel preadipocyte cell line established from mouse adult mature adipocytes. Biochem Biophys Res Comm 321: 967-974.
20. Poloni A, Maurizi G, Leoni P, Serrani F, Mancini S, et al. (2012) Human dedifferentiated adipocytes show similar properties to bone marrow-derived mesenchymal stem cells. Stem Cells 30: 965-974.
21. Toda S, Uchihashi K, Aoki S, Sonoda E, Yamasaki E, et al. (2009) Adipose tissue-organotypic culture system as a promising model for studying adipose tissue biology and regeneration. Organogenesis 5: 50-56.
22. Gustafson B, Smith U (2010) Activation of canonical wingless-type MMTV integration site family (Wnt) signaling in mature adipocytes increases β-catenin levels and leads to cell dedifferentiation and insulin resistance. J Biol Chem 285: 14031-14041.
23. Tejerina S, Pauw AD, Vankoningsloo S, Houbion A, Renard P, et al. (2009) Mild mitochondrial uncoupling induces 3T3-L1 adipocyte de-differentiation by a PPARγ-independent mechanism, whereas TNF-αinduced dedifferentiation is PPARγ dependent. J Cell Sci 122: 145-155.
24. Jo J, Gavrilova O, Pack S, Jou W, Mullen S, et al. (2009) Hypertrophy and/or hyperplasia: dynamics of adipose tissue growth. PLoS Comput Biol 5: e100324.
25. Spalding KL, Arner E, Westermark PO, Bernard S, Buchholz BA, et al. (2008) Dynamics of fat cell turnover in humans. Nature 453: 783-787.
26. Zhu L, Skoultchi A (2001) Coordinating cell proliferation and differentiation. Curr Opin Genet Dev 11: 91-97.
27. Brown G, Hughes PJ, Michell RH (2003) Cell differentiation and proliferation-simultaneous but independent? Exp Cell Res 291: 282-288.
28. Guo W, Zhang KM, Tu K, Li YX, Zhu L, et al. (2009) Adipogenesis licensing and execution are disparately linked to cell proliferation. Cell Res 19: 216-223.
29. Umek RM, Friedman AD, McKnight SL (1991) CCAAT-enhancer binding protein; a component of a differentiation switch. Science 251: 288-292.
30. Wu Z, Rosen ED, Burn R, Hauser S, Adelmant G, et al. (1999) Cross-regulation of C/EBPα and PPARγ controls the transcriptional pathway of adipogenesis and insulin sensitivity. Molecular Cell 3: 151-158.
31. Foster MT, Bartness TJ (2006) Sympathetic but not sensory denervation stimulates white adipocyte proliferation. Am J Physiol Regul Integr Comp Physiol 291: R1630-R1637.
32. Kajita K, Mori I, Hanamoto T, Ikeda T, Fujioka K, et al. (2012) Pioglitazone enhances small-sized adipocyte proliferation in subcutaneous adipose tissue. Endocr J 59: 1107-1114.
33. Mitaka T, Sato F, Mizuguchi T, Yokono T, Mochizuki Y (1999) Reconstruction of hepatic organoid by rat small hepatocytes and hepatic nonparenchymal cells. Hepatology 29: 111-125.