Mild mitochondrial uncoupling induces 3T3-L1 adipocyte de-differentiation by a PPARγ-independent mechanism, whereas TNFα-induced de-differentiation is PPARγ dependent

Journal of Cell Science

Volumn 122, Issue 1, 2009, Pages 145-155

  Tejerina, Silvia ^a   De Pauw, Aurélia ^a   Vankoningsloo, Sébastien ^a   Houbion, Andrée ^a   Renard, Patricia ^a   De Longueville, Françoise ^b   Raes, Martine ^a   Arnould, Thierry ^a  

^a UNIVERSITY OF NAMUR   (Belgium)

^b Eppendorf Array Technologies   (Belgium)

Author keywords

Adipocyte de differentiation; Gene expression; Mitochondrial dysfunction

Indexed keywords

ADIPONECTIN; ALITRETINOIN; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; FATTY ACID; GENE PRODUCT; GLUCOSE TRANSPORTER 4; PERILIPIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN PEPCK1; ROSIGLITAZONE; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; BIOLOGICAL MARKER; RETINOID X RECEPTOR; UNCOUPLING PROTEIN;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL ASSAY; CELL DEDIFFERENTIATION; CELL STRAIN 3T3; CONTROLLED STUDY; DOWN REGULATION; FATTY ACID OXIDATION; GENE EXPRESSION; GENE FUNCTION; GENETIC TRANSCRIPTION; LIPOGENESIS; LIPOLYSIS; MITOCHONDRIAL UNCOUPLING; MITOCHONDRION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PRIORITY JOURNAL; ANIMAL; DRUG EFFECT; GENE EXPRESSION PROFILING; LIPID METABOLISM; METABOLISM; PHYSIOLOGY;

3T3-L1 CELLS; ANIMALS; BIOLOGICAL MARKERS; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; CELL DEDIFFERENTIATION; GENE EXPRESSION PROFILING; LIPID METABOLISM; MICE; MITOCHONDRIA; PPAR GAMMA; RETINOID X RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA; UNCOUPLING AGENTS;

EID: 62149139816     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.027508     Document Type: Article

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