Neutron diffraction studies towards deciphering the protonation state of catalytic residues in the bacterial KDN9P phosphatase

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 69, Issue 9, 2013, Pages 1015-1019

  Bryan, Tyrel ^a   González, Javier M ^b   Bacik, John P ^b   Denunzio, Nicholas J ^c   Unkefer, Clifford J ^b   Schrader, Tobias E ^d   Ostermann, Andreas ^e   Dunaway Mariano, Debra ^a   Allen, Karen N ^c   Fisher, S Zoë ^b  

^a UNIVERSITY OF NEW MEXICO   (United States)

^b LOS ALAMOS NATIONAL LABORATORY   (United States)

^c USA   (United States)

^d FORSCHUNGSZENTRUM JÜLICH   (Germany)

^e TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

KDN9P phosphatase; neutron diffraction; protonation states

Indexed keywords

BACTERIAL PROTEIN; DIVALENT CATION; LIGAND; MAGNESIUM; PHOSPHATASE; PROTON; RECOMBINANT PROTEIN; SIALIC ACID DERIVATIVE;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLOGRAPHY; DEUTERIUM HYDROGEN EXCHANGE; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; KDN9P PHOSPHATASE; NEUTRON DIFFRACTION; PROTEIN BINDING; PROTONATION STATES; SMALL ANGLE SCATTERING;

KDN9P PHOSPHATASE; NEUTRON DIFFRACTION; PROTONATION STATES;

BACTERIAL PROTEINS; BINDING SITES; CATALYTIC DOMAIN; CATIONS, DIVALENT; CRYSTALLOGRAPHY; DEUTERIUM EXCHANGE MEASUREMENT; ESCHERICHIA COLI; GENE EXPRESSION; LIGANDS; MAGNESIUM; MODELS, MOLECULAR; NEUTRON DIFFRACTION; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN BINDING; PROTONS; RECOMBINANT PROTEINS; SCATTERING, SMALL ANGLE; SIALIC ACIDS; SUBSTRATE SPECIFICITY;

EID: 84883330718     PISSN: None     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309113021386     Document Type: Article

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