Identification of the elusive hydronium ion exchanging roles with a proton in an enzyme at lower pH values

Angewandte Chemie - International Edition

Volumn 50, Issue 33, 2011, Pages 7520-7523

  Kovalevsky, Andrey Y ^a   Hanson, B L ^b   Mason, S A ^c   Yoshida, T ^a   Fisher, S Z ^a   Mustyakimov, M ^a   Forsyth, V T ^c,d   Blakeley, M P ^c   Keen, D A ^e   Langan, Paul ^a,f  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF TOLEDO   (United States)

^c INSTITUT LAUE LANGEVIN   (France)

^d KEELE UNIVERSITY   (United Kingdom)

^e RUTHERFORD APPLETON LABORATORY   (United Kingdom)

^f OAK RIDGE NATIONAL LABORATORY   (United States)

Author keywords

enzymes; hydronium ions; neutron diffraction; protonation; X ray diffraction

Indexed keywords

ACIDIC CONDITIONS; ACTIVE SITE; BIOLOGICAL PROCESS; CRYSTALLOGRAPHIC STRUCTURE; HYDRONIUM IONS; METAL COFACTORS; PH VALUE;

ENZYMES; IONS; NEUTRON DIFFRACTION; NEUTRONS; PROTONS; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

ION SOURCES;

CATION; HYDRONIUM ION; ISOMERASE; PROTON; XYLOSE ISOMERASE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; PH; X RAY CRYSTALLOGRAPHY;

ALDOSE-KETOSE ISOMERASES; CRYSTALLOGRAPHY, X-RAY; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; ONIUM COMPOUNDS; PROTONS;

EID: 79961217081     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201101753     Document Type: Article

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