-
1
-
-
42649092874
-
Identification of ten loci associated with height highlights new biological pathways in human growth
-
Lettre G, Jackson AU, Gieger C et al. Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet 2008;40:584-591.
-
(2008)
Nat Genet
, vol.40
, pp. 584-591
-
-
Lettre, G.1
Jackson, A.U.2
Gieger, C.3
-
2
-
-
77957947562
-
Hundreds of variants clustered in genomic loci and biological pathways affect human height
-
Lango Allen H, Estrada K, Lettre G et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature 2010;467:832-838.
-
(2010)
Nature
, vol.467
, pp. 832-838
-
-
Lango Allen, H.1
Estrada, K.2
Lettre, G.3
-
3
-
-
78650904237
-
Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height
-
Lanktree MB, Guo Y, Murtaza M et al. Meta-analysis of dense genecentric association studies reveals common and uncommon variants associated with height. Am J Hum Genet 2011;88:6-18.
-
(2011)
Am J Hum Genet
, vol.88
, pp. 6-18
-
-
Lanktree, M.B.1
Guo, Y.2
Murtaza, M.3
-
4
-
-
53949088050
-
Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA
-
Heo I, Joo C, Cho J et al. Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA. Mol Cell 2008;32:276-284.
-
(2008)
Mol Cell
, vol.32
, pp. 276-284
-
-
Heo, I.1
Joo, C.2
Cho, J.3
-
5
-
-
47949100595
-
Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing
-
Newman MA, Thomson JM, Hammond SM. Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing. RNA 2008;14:1539.
-
(2008)
RNA
, vol.14
, pp. 1539
-
-
Newman, M.A.1
Thomson, J.M.2
Hammond, S.M.3
-
6
-
-
52049124806
-
Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28
-
Piskounova E, Viswanathan SR, Janas M et al. Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. J Biol Chem 2008;283: 21310-21314.
-
(2008)
J Biol Chem
, vol.283
, pp. 21310-21314
-
-
Piskounova, E.1
Viswanathan, S.R.2
Janas, M.3
-
7
-
-
48649103982
-
A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
-
Rybak A, Fuchs H, Smirnova L et al. A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment. Nat Cell Biol 2008;10:987-993.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 987-993
-
-
Rybak, A.1
Fuchs, H.2
Smirnova, L.3
-
8
-
-
40849108663
-
Selective blockade of micro-RNA processing by Lin28
-
Viswanathan SR, Daley GQ, Gregory RI. Selective blockade of micro-RNA processing by Lin28. Science 2008;320:97-100.
-
(2008)
Science
, vol.320
, pp. 97-100
-
-
Viswanathan, S.R.1
Daley, G.Q.2
Gregory, R.I.3
-
9
-
-
35548967996
-
A novel role for an embryonic regulatory protein Lin-28 in adult skeletal muscle differentiation[rsqb]
-
[lsqb]
-
Polesskaya A, Harel-Bellan A. [lsqb]A novel role for an embryonic regulatory protein Lin-28 in adult skeletal muscle differentiation[rsqb]. Med Sci (Paris) 2007;23:796-797.
-
(2007)
Med Sci (Paris)
, vol.23
, pp. 796-797
-
-
Polesskaya, A.1
Harel-Bellan, A.2
-
10
-
-
77950344768
-
Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells
-
Qiu C, Ma Y, Wang J et al. Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells. Nucleic Acids Res 2010;38:1240-1248.
-
(2010)
Nucleic Acids Res
, vol.38
, pp. 1240-1248
-
-
Qiu, C.1
Ma, Y.2
Wang, J.3
-
11
-
-
60849116964
-
Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells
-
Xu B, Zhang K, Huang Y. Lin28 modulates cell growth and associates with a subset of cell cycle regulator mRNAs in mouse embryonic stem cells. RNA 2009;15:357-361.
-
(2009)
RNA
, vol.15
, pp. 357-361
-
-
Xu, B.1
Zhang, K.2
Huang, Y.3
-
12
-
-
66649105485
-
Genetic variation in LIN28B is associated with the timing of puberty
-
Ong KK, Elks CE, Li S et al. Genetic variation in LIN28B is associated with the timing of puberty. Nat Genet 2009;41:729-733.
-
(2009)
Nat Genet
, vol.41
, pp. 729-733
-
-
Ong, K.K.1
Elks, C.E.2
Li, S.3
-
13
-
-
66649116283
-
Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche
-
Sulem P, Gudbjartsson DF, Rafnar T et al. Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche. Nat Genet 2009;41:734-738.
-
(2009)
Nat Genet
, vol.41
, pp. 734-738
-
-
Sulem, P.1
Gudbjartsson, D.F.2
Rafnar, T.3
-
14
-
-
66649090056
-
Genome-wide association studies identify loci associated with age at menarche and age at natural menopause
-
He C, Kraft P, Chen C et al. Genome-wide association studies identify loci associated with age at menarche and age at natural menopause. Nat Genet 2009;41:724-728.
-
(2009)
Nat Genet
, vol.41
, pp. 724-728
-
-
He, C.1
Kraft, P.2
Chen, C.3
-
15
-
-
66649123583
-
Meta-analysis of genomewide association data identifies two loci influencing age at menarche
-
Perry JR, Stolk L, Franceschini N et al. Meta-analysis of genomewide association data identifies two loci influencing age at menarche. Nat Genet 2009;41:648-650.
-
(2009)
Nat Genet
, vol.41
, pp. 648-650
-
-
Perry, J.R.1
Stolk, L.2
Franceschini, N.3
-
16
-
-
0021771445
-
Heterochronic mutants of the nematode Caenorhabditis elegans
-
Ambros V, Horvitz HR. Heterochronic mutants of the nematode Caenorhabditis elegans. Science 1984;226:409-416.
-
(1984)
Science
, vol.226
, pp. 409-416
-
-
Ambros, V.1
Horvitz, H.R.2
-
17
-
-
0030970775
-
The cold shock domain protein LIN-28 controls developmental timing in C. Elegans and is regulated by the lin-4 RNA
-
Moss EG, Lee RC, Ambros V. The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA. Cell 1997;88:637-646.
-
(1997)
Cell
, vol.88
, pp. 637-646
-
-
Moss, E.G.1
Lee, R.C.2
Ambros, V.3
-
18
-
-
0034708122
-
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
-
Reinhart BJ, Slack FJ, Basson M et al. The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature 2000;403:901-906.
-
(2000)
Nature
, vol.403
, pp. 901-906
-
-
Reinhart, B.J.1
Slack, F.J.2
Basson, M.3
-
19
-
-
67649556287
-
An elegant miRror: MicroRNAs in stem cells, developmental timing and cancer
-
Nimmo RA, Slack FJ. An elegant miRror: MicroRNAs in stem cells, developmental timing and cancer. Chromosoma 2009;118:405-418.
-
(2009)
Chromosoma
, vol.118
, pp. 405-418
-
-
Nimmo, R.A.1
Slack, F.J.2
-
20
-
-
0037783427
-
Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites
-
Moss EG, Tang L. Conservation of the heterochronic regulator Lin-28, its developmental expression and microRNA complementary sites. Dev Biol 2003;258:432-442.
-
(2003)
Dev Biol
, vol.258
, pp. 432-442
-
-
Moss, E.G.1
Tang, L.2
-
21
-
-
28444475503
-
Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis
-
Schulman BR, Esquela-Kerscher A, Slack FJ, Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis. Dev Dyn 2005;234:1046-1054.
-
(2005)
Dev Dyn
, vol.234
, pp. 1046-1054
-
-
Schulman, B.R.1
Esquela-Kerscher, A.2
Slack, F.J.3
-
22
-
-
77954144740
-
Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies
-
Zhu H, Shah S, Shyh-Chang N et al. Lin28a transgenic mice manifest size and puberty phenotypes identified in human genetic association studies. Nat Genet 2010;42:626-630.
-
(2010)
Nat Genet
, vol.42
, pp. 626-630
-
-
Zhu, H.1
Shah, S.2
Shyh-Chang, N.3
-
23
-
-
80053481600
-
The Lin28/let-7 axis regulates glucose metabolism
-
Zhu H, Shyh-Chang N, Segre AV et al. The Lin28/let-7 axis regulates glucose metabolism. Cell 2011;147:81-94.
-
(2011)
Cell
, vol.147
, pp. 81-94
-
-
Zhu, H.1
Shyh-Chang, N.2
Segre, A.V.3
-
24
-
-
26444545103
-
Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction
-
Belteki G, Haigh J, Kabacs N et al. Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction. Nucleic Acids Res 2005;33:e51.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Belteki, G.1
Haigh, J.2
Kabacs, N.3
-
25
-
-
84860352139
-
A positive/negative ion-switching, targeted mass spectrometry-based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue
-
Yuan M, Breitkopf SB, Yang X et al. A positive/negative ion-switching, targeted mass spectrometry-based metabolomics platform for bodily fluids, cells, and fresh and fixed tissue. Nat Protoc 2012;7:872-881.
-
(2012)
Nat Protoc
, vol.7
, pp. 872-881
-
-
Yuan, M.1
Breitkopf, S.B.2
Yang, X.3
-
26
-
-
33751042873
-
Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma
-
Guo Y, Chen Y, Ito H et al. Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma. Gene 2006;384:51-61.
-
(2006)
Gene
, vol.384
, pp. 51-61
-
-
Guo, Y.1
Chen, Y.2
Ito, H.3
-
27
-
-
70350778443
-
An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation
-
Iliopoulos D, Hirsch HA, Struhl K. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell 2009;139:693-706.
-
(2009)
Cell
, vol.139
, pp. 693-706
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
28
-
-
67649881121
-
Lin28 promotes transformation and is associated with advanced human malignancies
-
Viswanathan SR, Powers JT, Einhorn W et al. Lin28 promotes transformation and is associated with advanced human malignancies. Nat Genet 2009;41:843-848.
-
(2009)
Nat Genet
, vol.41
, pp. 843-848
-
-
Viswanathan, S.R.1
Powers, J.T.2
Einhorn, W.3
-
29
-
-
68949131095
-
A role for Lin28 in primordial germ-cell development and germ-cell malignancy
-
West JA, Viswanathan SR, Yabuuchi A et al. A role for Lin28 in primordial germ-cell development and germ-cell malignancy. Nature 2009;460:909-913.
-
(2009)
Nature
, vol.460
, pp. 909-913
-
-
West, J.A.1
Viswanathan, S.R.2
Yabuuchi, A.3
-
30
-
-
81855183636
-
Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms
-
Piskounova E, Polytarchou C, Thornton JE et al. Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Cell 2011; 147:1066-1079.
-
(2011)
Cell
, vol.147
, pp. 1066-1079
-
-
Piskounova, E.1
Polytarchou, C.2
Thornton, J.E.3
-
31
-
-
0344013522
-
Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse
-
Yang DH, Moss EG. Temporally regulated expression of Lin-28 in diverse tissues of the developing mouse. Gene Expr Patterns 2003;3: 719-726.
-
(2003)
Gene Expr Patterns
, vol.3
, pp. 719-726
-
-
Yang, D.H.1
Moss, E.G.2
-
32
-
-
84855518254
-
Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs
-
Frost RJ, Olson EN. Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs. Proc Natl Acad Sci USA 2011;108:21075-21080.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 21075-21080
-
-
Frost, R.J.1
Olson, E.N.2
-
33
-
-
84859778293
-
MTOR signaling in growth control and disease
-
Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell 2012;149:274-293.
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
34
-
-
0036501277
-
A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells
-
Kwiatkowski DJ, Zhang H, Bandura JL et al. A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells. Hum Mol Genet 2002;11:525-534.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 525-534
-
-
Kwiatkowski, D.J.1
Zhang, H.2
Bandura, J.L.3
-
35
-
-
0026772772
-
Type 2 (non-insulin-dependent) diabetes mellitus: The thrifty phenotype hypothesis
-
Hales CN, Barker DJ. Type 2 (non-insulin-dependent) diabetes mellitus: The thrifty phenotype hypothesis. Diabetologia 1992;35:595-601.
-
(1992)
Diabetologia
, vol.35
, pp. 595-601
-
-
Hales, C.N.1
Barker, D.J.2
-
36
-
-
0035704552
-
The thrifty phenotype hypothesis
-
Hales CN, Barker DJ. The thrifty phenotype hypothesis. Br Med Bull 2001;60:5-20.
-
(2001)
Br Med Bull
, vol.60
, pp. 5-20
-
-
Hales, C.N.1
Barker, D.J.2
|