Identifying cellular mechanisms of zinc-induced relaxation in isolated cardiomyocytes

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 305, Issue 5, 2013, Pages

  Yi, Ting ^a   Vick, Jonathan S ^a   Vecchio, Marc J H ^a   Begin, Kelly J ^b   Bell, Stephen P ^b   Delay, Rona J ^a   Palmer, Bradley M ^a  

^a UNIVERSITY OF VERMONT   (United States)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

Cardiac; L type channel; Myocyte; Ryanodine receptor; Sarcomere

Indexed keywords

CAFFEINE; CALCIUM CHANNEL L TYPE; CALCIUM ION; FURA 2; PHOSPHOLAMBAN; RYANODINE RECEPTOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM ION; ZINC ION;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOLOGICAL MONITORING; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM TRANSPORT; CELL ISOLATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; EXPOSURE; EXTRACELLULAR SPACE; HEART CONTRACTION; HEART MUSCLE CELL; HEART MUSCLE RELAXATION; HEART PAPILLARY MUSCLE; HEART PERFUSION; MALE; MOUSE; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; RAT; SARCOMERE LENGTH; THIN FILAMENT;

CARDIAC; L-TYPE CHANNEL; MYOCYTE; RYANODINE RECEPTOR; SARCOMERE;

ANIMALS; CALCIUM; CALCIUM CHANNELS, L-TYPE; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MICE; MICE, INBRED C57BL; MODELS, ANIMAL; MUSCLE RELAXATION; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; RATS; RATS, INBRED WKY; RATS, SPRAGUE-DAWLEY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOMERES; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; ZINC;

EID: 84883311506     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00025.2013     Document Type: Article

References (39)

1. Atar D, Backx PH, Appel MM, Gao WD, Marban E. Excitationtranscription coupling mediated by zinc influx through voltage-dependent calcium channels. J Biol Chem 270: 2473-2477, 1995.
2. 2+ current in rat cardiac myocytes. Cardiovasc Res 42: 113-120, 1999.
3. Baltas LG, Karczewski P, Krause EG. Effects of zinc on phospholamban phosphorylation. Biochem Biophys Res Commun 232: 394-397, 1997.
4. Bers DM. Cardiac excitation-contraction coupling. Nature 415: 198-205, 2002.
5. Bogden JD, Oleske JM, Munves EM, Lavenhar MA, Bruening KS, Kemp FW, Holding KJ, Denny TN, Louria DB. Zinc and immunocompetence in the elderly: baseline data on zinc nutriture and immunity in unsupplemented subjects. Am J Clin Nutr 46: 101-109, 1987.
6. 2+ exchanger. Neuroreport 9: 3091-3096, 1998.
7. Devinney MJ, 2nd Reynolds IJ, Dineley KE. Simultaneous detection of intracellular free calcium and zinc using fura-2FF and FluoZin-3. Cell Calcium 37: 225-232, 2005.
8. Eby GA, Halcomb WW. High-dose zinc to terminate angina pectoris: a review and hypothesis for action by ICAM inhibition. Med Hypotheses 66: 169-172, 2006.
9. Fliss H, Menard M, Desai M. Hypochlorous acid mobilizes cellular zinc. Can J Physiol Pharmacol 69: 1686-1691, 1991.
10. Francis SH, Blount MA, Corbin JD. Mammalian cyclic nucleotide phosphodiesterases: molecular mechanisms and physiological functions. Physiol Rev 91: 651-690, 2011.
11. Hyrc KL, Bownik JM, Goldberg MP. Ionic selectivity of low-affinity ratiometric calcium indicators: mag-Fura-2, Fura-2FF and BTC. Cell Calcium 27: 75-86, 2000.
12. Kamp TJ, Hell JW. Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C. Circ Res 87: 1095-1102, 2000.
13. Kang YJ. The antioxidant function of metallothionein in the heart. Proc Soc Exper Biol Med 222: 263-273, 1999.
14. Karlin S, Zhu ZY. Classification of mononuclear zinc metal sites in protein structures. Proc Natl Acad Sci USA 94: 14231-14236, 1997.
15. Maret W. The function of zinc metallothionein: a link between cellular zinc and redox state. J Nutr 130: 1455S-1458S, 2000.
16. Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101: 365-376, 2000.
17. Ohana E, Segal D, Palty R, Ton-That D, Moran A, Sensi SL, Weiss JH, Hershfinkel M, Sekler I. A sodium zinc exchange mechanism is mediating extrusion of zinc in mammalian cells. J Biol Chem 279: 4278-4284, 2004.
18. Oster O, Dahm M, Oelert H. Element concentrations (selenium, copper, zinc, iron, magnesium, potassium, phosphorous) in heart tissue of patients with coronary heart disease correlated with physiological parameters of the heart. Eur Heart J 14: 770-774, 1993.
19. 2+] and fluorescence ratio. Am J Physiol Cell Physiol 279: C1278-C1284, 2000.
20. Palmer BM, Vogt S, Chen Z, Lachapelle RR, Lewinter MM. Intracellular distributions of essential elements in cardiomyocytes. J Struct Biol 155: 12-21, 2006.
21. Pepersack T, Rotsaert P, Benoit F, Willems D, Fuss M, Bourdoux P, Duchateau J. Prevalence of zinc deficiency and its clinical relevance among hospitalised elderly. Arch Gerontol Geriatr 33: 243-253, 2001.
22. 2+-binding protein of skeletal muscle sarcoplasmic reticulum. Biochem Biophys Res Commun 186: 659-667, 1992.
23. Powell SR, Aiuto L, Hall D, Tortolani AJ. Zinc supplementation enhances the effectiveness of St. Thomas' Hospital No 2 cardioplegic solution in an in vitro model of hypothermic cardiac arrest. J Thorac Cardiovasc Surg 110: 1642-1648, 1995.
24. Powell SR, Hall D, Aiuto L, Wapnir RA, Teichberg S, Tortolani AJ. Zinc improves postischemic recovery of isolated rat hearts through inhibition of oxidative stress. Am J Physiol Heart Circ Physiol 266: H2497-H2507, 1994.
25. Powell SR, Nelson RL, Finnerty J, Alexander D, Pottanat G, Kooker K, Schiff RJ, Moyse J, Teichberg S, Tortolani AJ. Zinc-bis-histidinate preserves cardiac function in a porcine model of cardioplegic arrest. Ann Thorac Surg 64: 73-80, 1997.
26. Prasad AS. Discovery of human zinc deficiency: 50 years later. J Trace Elem Med Biol 26: 66-69, 2012.
27. Prasad AS, Bao B, Beck FW, Kucuk O, Sarkar FH. Antioxidant effect of zinc in humans. Free Radic Biol Med 37: 1182-1190, 2004.
28. Selby DE, Palmer BM, LeWinter MM, Meyer M. Tachycardia-induced diastolic dysfunction and resting tone in myocardium from patients with a normal ejection fraction. J Am Coll Cardiol 58: 147-154, 2011.
29. Shan J, Betzenhauser MJ, Kushnir A, Reiken S, Meli AC, Wronska A, Dura M, Chen BX, Marks AR. Role of chronic ryanodine receptor phosphorylation in heart failure and beta-adrenergic receptor blockade in mice. J Clin Invest 120: 4375-4387, 2010.
30. Shao CH, Wehrens XH, Wyatt TA, Parbhu S, Rozanski GJ, Patel KP, Bidasee KR. Exercise training during diabetes attenuates cardiac ryanodine receptor dysregulation. J Appl Physiol 106: 1280-1292, 2009.
31. Shokrzadeh M, Ghaemian A, Salehifar E, Aliakbari S, Saravi SS, Ebrahimi P. Serum zinc and copper levels in ischemic cardiomyopathy. Biol Trace Elem Res 127: 116-123, 2009.
32. Tuncay E, Bilginoglu A, Sozmen NN, Zeydanli EN, Ugur M, Vassort G, Turan B. Intracellular free zinc during cardiac excitation-contraction cycle: calcium and redox dependencies. Cardiovasc Res 89: 634-642, 2011.
33. Turan B. Zinc-induced changes in ionic currents of cardiomyocytes. Biol Trace Elem Res 94: 49-60, 2003.
34. 2+ concentration in rabbit ventricular myocytes. Am J Physiol Heart Circ Physiol 272: H2095-H2106, 1997.
35. 2+ channels. Cardiovasc Res 65: 28-39, 2005.
36. Vassort G, Turan B. Protective role of antioxidants in diabetes-induced cardiac dysfunction. Cardiovasc Toxicol 10: 73-86, 2010.
37. 2+ sparks by mitochondria-derived reactive oxygen species in cardiac myocytes. Cardiovasc Res 77: 432-441, 2008.
38. 2+ homeostasis in rat heart. Diabetes 54: 3082-3088, 2005.
39. Yi T, Cheema Y, Tremble SM, Bell SP, Chen Z, Subramanian M, LeWinter MM, VanBuren P, Palmer BM. Zinc-induced cardiomyocyte relaxation in a rat model of hyperglycemia is independent of myosin isoform. Cardiovasc Diabetol 11: 135, 2012.