Matched miRNA and mRNA signatures from an hESC-based in vitro model of pancreatic differentiation reveal novel regulatory interactions

Journal of Cell Science

Volumn 126, Issue 17, 2013, Pages 3848-3861

  Liao, Xiaoyan ^a,b   Xue, Haipeng ^a,b,c   Wang, Yu Chieh ^b   Nazor, Kristopher L ^b   Guo, Shuren ^a,b,d   Trivedi, Neha ^a   Peterson, Suzanne E ^b   Liu, Ying ^a,b,c   Loring, Jeanne F ^b   Laurent, Louise C ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^d ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

Beta cell; Gene expression; miRNA; Pancreatic differentiation; Stem cell

Indexed keywords

INSULIN; LUCIFERASE; LUCIFERASE REPORTER; MESSENGER RNA; MICRORNA; MICRORNA 200; MICRORNA 200A; RFX6 PROTEIN; TRANSCRIPTION FACTOR SOX17; UNCLASSIFIED DRUG; ZEB2 PROTEIN;

ANATOMICAL CONCEPTS; ARTICLE; BETA ISLET PRECURSOR CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL LINEAGE; CELL MATURATION; CELL SPECIFICITY; COMPARATIVE STUDY; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EMBRYO; EMBRYONIC STEM CELL; ENDODERM; ENZYME ASSAY; EPITHELIAL MESENCHYMAL TRANSITION; GENE; GENE CONTROL; GENE EXPRESSION; GENE FUNCTION; GENE INTERACTION; GENE TARGETING; HORMONE EXPRESSING ENDOCRINE CELL; HUMAN; HUMAN CELL; HUMAN EMBRYONIC STEM CELL; HUMAN FETAL PANCREAS; HUMAN PLURIPOTENT STEM CELL; HUMAN TISSUE; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; LET 7E GENE; LUCIFERASE REPORTER ASSAY; MICROARRAY ANALYSIS; MIR 30D GENE; ORGANOGENESIS; PANCREAS CELL; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL; PANCREATIC PROGENITOR CELL; PLURIPOTENT STEM CELL; POSTERIOR FOREGUT; PREDICTION; PRIMITIVE GUT TUBE; PRIORITY JOURNAL; REGULATORY MECHANISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; TRANSCRIPTION REGULATION; WESTERN BLOTTING; ZEB2 GENE;

BETA CELL; GENE EXPRESSION; MIRNA; PANCREATIC DIFFERENTIATION; STEM CELL;

CELL DIFFERENTIATION; CELL LINEAGE; CELL- AND TISSUE-BASED THERAPY; CELLS, CULTURED; DIABETES MELLITUS, TYPE 1; DNA-BINDING PROTEINS; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HOMEODOMAIN PROTEINS; HUMANS; INSULIN-SECRETING CELLS; MICRORNAS; PANCREAS; PLURIPOTENT STEM CELLS; REPRESSOR PROTEINS; RNA, MESSENGER; SOXF TRANSCRIPTION FACTORS; TRANSCRIPTION FACTORS;

EID: 84883291103     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.123570     Document Type: Article

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