Human cytomegalovirus interleukin-10 polarizes monocytes toward a deactivated m2c phenotype to repress host immune responses

Journal of Virology

Volumn 87, Issue 18, 2013, Pages 10273-10282

  Avdic, Selmir ^a,b   Cao, John Z ^a,b   McSharry, Brian P ^b   Clancy, Leighton E ^b   Brown, Rebecca ^b   Steain, Megan ^b   Gottlieb, David J ^b   Abendroth, Allison ^a,b   Slobedman, Barry ^a,b  

^a WESTMEAD HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CD150 ANTIGEN; CD163 ANTIGEN; CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR7; FIBRONECTIN; HEME OXYGENASE 1; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 1BETA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MERLIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TUMOR NECROSIS FACTOR ALPHA; VERSICAN;

ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CELL FUNCTION; CELL POLARITY; CELLULAR SECRETION; CONTROLLED STUDY; CYTOMEGALOVIRUS INFECTION; ENZYME INHIBITION; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; IMMUNE RESPONSE; IMMUNITY; INFLAMMATION; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MONOCYTE; NONHUMAN; PHENOTYPE; POLARIZATION; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; UPREGULATION; VIRAL CLEARANCE; VIRUS PATHOGENESIS;

ANTIGENS, CD; ANTIGENS, CD14; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; CYTOMEGALOVIRUS; HEME OXYGENASE-1; HISTOCOMPATIBILITY ANTIGENS CLASS II; HOST-PATHOGEN INTERACTIONS; HUMANS; IMMUNE EVASION; INTERLEUKIN-10; MONOCYTES; RECEPTORS, CELL SURFACE; VIRAL PROTEINS; VIRULENCE FACTORS;

EID: 84883280721     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00912-13     Document Type: Article

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