-
1
-
-
0029762351
-
Human cytomegalovirus inhibits antigen presentation by a sequential multistep process
-
Ahn, K., A. Angulo, P. Ghazal, P. A. Peterson, Y. Yang, and K. Fruh. 1996. Human cytomegalovirus inhibits antigen presentation by a sequential multistep process. Proc. Natl. Acad. Sci. USA 93:10990-10995.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10990-10995
-
-
Ahn, K.1
Angulo, A.2
Ghazal, P.3
Peterson, P.A.4
Yang, Y.5
Fruh, K.6
-
2
-
-
0141960095
-
A survival game of hide and seek: Cytomegaloviruses and MHC class I antigen presentation pathways
-
Basta, S., and J. R. Bennink. 2003. A survival game of hide and seek: cytomegaloviruses and MHC class I antigen presentation pathways. Viral Immunol. 16:231-242.
-
(2003)
Viral Immunol
, vol.16
, pp. 231-242
-
-
Basta, S.1
Bennink, J.R.2
-
3
-
-
0023841944
-
Human cytomegalovirus encodes a glycoprotein homologous to MHC class-I antigens
-
Beck, S., and B. G. Barrell. 1988. Human cytomegalovirus encodes a glycoprotein homologous to MHC class-I antigens. Nature 331:269-272.
-
(1988)
Nature
, vol.331
, pp. 269-272
-
-
Beck, S.1
Barrell, B.G.2
-
4
-
-
3843104695
-
Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IκB kinase activity
-
Bhattacharyya, S., P. Sen, M. Wallet, B. Long, A. S. Baldwin, Jr., and R. Tisch. 2004. Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IκB kinase activity. Blood 104:1100-1109.
-
(2004)
Blood
, vol.104
, pp. 1100-1109
-
-
Bhattacharyya, S.1
Sen, P.2
Wallet, M.3
Long, B.4
Baldwin Jr., A.S.5
Tisch, R.6
-
5
-
-
0001450002
-
Cytomegalovirus
-
B. N. Fields, D. M. Knipe, and P. M. Howley ed, 3rd ed. Lippincott-Raven Publishers, Philadelphia, PA
-
Britt, W. J., and C. A. Alford. 1996. Cytomegalovirus, p. 2493-2523. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields virology, 3rd ed. Lippincott-Raven Publishers, Philadelphia, PA.
-
(1996)
Fields virology
, pp. 2493-2523
-
-
Britt, W.J.1
Alford, C.A.2
-
6
-
-
33846832472
-
HCMV-encoded IL-10 alters dendritic cell functionality: A comprehensive comparison with cellular IL-10, abstr. 6.40. 29th Int
-
Reno, NV
-
Chang, W., N. Baumgarth, J. P. Greg, C. A. Baron, and P. A. Barry. 2004. HCMV-encoded IL-10 alters dendritic cell functionality: a comprehensive comparison with cellular IL-10, abstr. 6.40. 29th Int. Herpesvirus Workshop, Reno, NV.
-
(2004)
Herpesvirus Workshop
-
-
Chang, W.1
Baumgarth, N.2
Greg, J.P.3
Baron, C.A.4
Barry, P.A.5
-
7
-
-
3543055705
-
Human cytomegalovirus-encoded interleukin-10 homolog inhibits maturation of dendritic cells and alters their functionality
-
Chang, W. L., N. Baumgarth, D. Yu, and P. A. Barry. 2004. Human cytomegalovirus-encoded interleukin-10 homolog inhibits maturation of dendritic cells and alters their functionality. J. Virol. 78:8720-8731.
-
(2004)
J. Virol
, vol.78
, pp. 8720-8731
-
-
Chang, W.L.1
Baumgarth, N.2
Yu, D.3
Barry, P.A.4
-
8
-
-
0030037906
-
Interleukin-10 stimulation of phosphatidylinositol 3-kinase and p70 S6 kinase is required for the proliferative but not the antiinflammatory effects of the cytokine
-
Crawley, J. B., L. M. Williams, T. Mander, F. M. Brennan, and B. M. Foxwell. 1996. Interleukin-10 stimulation of phosphatidylinositol 3-kinase and p70 S6 kinase is required for the proliferative but not the antiinflammatory effects of the cytokine. J. Biol. Chem. 271:16357-16362.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 16357-16362
-
-
Crawley, J.B.1
Williams, L.M.2
Mander, T.3
Brennan, F.M.4
Foxwell, B.M.5
-
10
-
-
0034658024
-
Serine phosphorylation of STATs
-
Decker, T., and P. Kovarik. 2000. Serine phosphorylation of STATs. Oncogene 19:2628-2637.
-
(2000)
Oncogene
, vol.19
, pp. 2628-2637
-
-
Decker, T.1
Kovarik, P.2
-
11
-
-
0036701617
-
Diagnosis and treatment approaches of CMV infections in adult patients
-
de la Hoz, R. E., G. Stephens, and C. Sherlock. 2002. Diagnosis and treatment approaches of CMV infections in adult patients. J. Clin. Virol. 25(Suppl. 2):S1-S12.
-
(2002)
J. Clin. Virol
, vol.25
, Issue.SUPPL. 2
-
-
de la Hoz, R.E.1
Stephens, G.2
Sherlock, C.3
-
12
-
-
0026094306
-
Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
-
de Waal Malefyt, R., J. Abrams, B. Bennett, C. G. Figdor, and J. E. de Vries. 1991. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174:1209-1220.
-
(1991)
J. Exp. Med
, vol.174
, pp. 1209-1220
-
-
de Waal Malefyt, R.1
Abrams, J.2
Bennett, B.3
Figdor, C.G.4
de Vries, J.E.5
-
13
-
-
0032779561
-
The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes
-
Donnelly, R. P., H. Dickensheets, and D. S. Finbloom. 1999. The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes. J. Interferon Cytokine Res. 19:563-573.
-
(1999)
J. Interferon Cytokine Res
, vol.19
, pp. 563-573
-
-
Donnelly, R.P.1
Dickensheets, H.2
Finbloom, D.S.3
-
14
-
-
0029118395
-
IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes
-
Finbloom, D. S., and K. D. Winestock. 1995. IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes. J. Immunol. 155:1079-1090.
-
(1995)
J. Immunol
, vol.155
, pp. 1079-1090
-
-
Finbloom, D.S.1
Winestock, K.D.2
-
15
-
-
33846833104
-
Immunomodulation by a viral homolog of IL-10 expressed by human cytomegalovirus during the latent phase of infection, abstr. 2.01. 31st Int
-
Seattle, WA
-
Godwin, M., A. Cheung, C. Jenkins, J. Lewis Stern, B. Plachter, S. Pepperl-Klindworth, A. Abendroth, and B. Slobedman. 2006. Immunomodulation by a viral homolog of IL-10 expressed by human cytomegalovirus during the latent phase of infection, abstr. 2.01. 31st Int. Herpesvirus Workshop, Seattle, WA.
-
(2006)
Herpesvirus Workshop
-
-
Godwin, M.1
Cheung, A.2
Jenkins, C.3
Lewis Stern, J.4
Plachter, B.5
Pepperl-Klindworth, S.6
Abendroth, A.7
Slobedman, B.8
-
16
-
-
0032077622
-
Immune evasion by cytomegalovirus - survival strategies of a highly adapted opportunist
-
Hengel, H., W. Brune, and U. H. Koszinowski. 1998. Immune evasion by cytomegalovirus - survival strategies of a highly adapted opportunist. Trends Microbiol. 6:190-197.
-
(1998)
Trends Microbiol
, vol.6
, pp. 190-197
-
-
Hengel, H.1
Brune, W.2
Koszinowski, U.H.3
-
17
-
-
0346373693
-
A novel viral transcript with homology to human interleukin-10 is expressed during latent human cytomegalovirus infection
-
Jenkins, C., A. Abendroth, and B. Slobedman. 2004. A novel viral transcript with homology to human interleukin-10 is expressed during latent human cytomegalovirus infection. J. Virol. 78:1440-1447.
-
(2004)
J. Virol
, vol.78
, pp. 1440-1447
-
-
Jenkins, C.1
Abendroth, A.2
Slobedman, B.3
-
18
-
-
0037047128
-
Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1
-
Jones, B. C., N. J. Logsdon, K. Josephson, J. Cook, P. A. Barry, and M. R. Walter. 2002. Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1. Proc. Natl. Acad. Sci. USA 99:9404-9409.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 9404-9409
-
-
Jones, B.C.1
Logsdon, N.J.2
Josephson, K.3
Cook, J.4
Barry, P.A.5
Walter, M.R.6
-
19
-
-
0035992506
-
The family of IL-10-related cytokines and their receptors: Related, but to what extent?
-
Kotenko, S. V. 2002. The family of IL-10-related cytokines and their receptors: related, but to what extent? Cytokine Growth Factor Rev. 13:223-240.
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, pp. 223-240
-
-
Kotenko, S.V.1
-
20
-
-
0034658583
-
Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes
-
Kotenko, S. V., and S. Pestka. 2000. Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes. Oncogene 19:2557-2565.
-
(2000)
Oncogene
, vol.19
, pp. 2557-2565
-
-
Kotenko, S.V.1
Pestka, S.2
-
21
-
-
0034652261
-
Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10)
-
Kotenko, S. V., S. Saccani, L. S. Izotova, O. V. Mirochnitchenko, and S. Pestka. 2000. Human cytomegalovirus harbors its own unique IL-10 homolog (cmvIL-10). Proc. Natl. Acad. Sci. USA 97:1695-1700.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 1695-1700
-
-
Kotenko, S.V.1
Saccani, S.2
Izotova, L.S.3
Mirochnitchenko, O.V.4
Pestka, S.5
-
22
-
-
0033197954
-
Inhibition of Kit expression by IL-4 and IL-10 in murine mast cells: Role of STAT6 and phosphatidylinositol 3′-kinase
-
Mirmonsef, P., C. P. Shelburne, C. Fitzhugh Yeatman II, H. J. Chong, and J. J. Ryan. 1999. Inhibition of Kit expression by IL-4 and IL-10 in murine mast cells: role of STAT6 and phosphatidylinositol 3′-kinase. J. Immunol. 163:2530-2539.
-
(1999)
J. Immunol
, vol.163
, pp. 2530-2539
-
-
Mirmonsef, P.1
Shelburne, C.P.2
Fitzhugh Yeatman II, C.3
Chong, H.J.4
Ryan, J.J.5
-
23
-
-
0035062021
-
Interleukin-10 and the interleukin-10 receptor
-
Moore, K. W., R. de Waal Malefyt, R. L. Coffman, and A. O'Garra. 2001. Interleukin-10 and the interleukin-10 receptor. Annu. Rev. Immunol. 19:683-765.
-
(2001)
Annu. Rev. Immunol
, vol.19
, pp. 683-765
-
-
Moore, K.W.1
de Waal Malefyt, R.2
Coffman, R.L.3
O'Garra, A.4
-
24
-
-
24044551995
-
PI3K/Akt/mTOR pathway as a target for cancer therapy
-
Morgensztern, D., and H. L. McLeod. 2005. PI3K/Akt/mTOR pathway as a target for cancer therapy. Anticancer Drugs 16:797-803.
-
(2005)
Anticancer Drugs
, vol.16
, pp. 797-803
-
-
Morgensztern, D.1
McLeod, H.L.2
-
25
-
-
0032481383
-
IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: Evidence for Stat3-dependent and -independent pathways
-
O'Farrell, A. M., Y. Liu, K. W. Moore, and A. L. Mui. 1998. IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways. EMBO J. 17:1006-1018.
-
(1998)
EMBO J
, vol.17
, pp. 1006-1018
-
-
O'Farrell, A.M.1
Liu, Y.2
Moore, K.W.3
Mui, A.L.4
-
26
-
-
0033915344
-
Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase
-
Pahan, K., M. Khan, and I. Singh. 2000. Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase. J. Neurochem. 75:576-582.
-
(2000)
J. Neurochem
, vol.75
, pp. 576-582
-
-
Pahan, K.1
Khan, M.2
Singh, I.3
-
27
-
-
4344682020
-
Shaping phenotype, function, and survival of dendritic cells by cytomegalovirus-encoded IL-10
-
Raftery, M. J., D. Wieland, S. Gronewald, A. A. Kraus, T. Giese, and G. Schonrich. 2004. Shaping phenotype, function, and survival of dendritic cells by cytomegalovirus-encoded IL-10. J. Immunol. 173:3383-3391.
-
(2004)
J. Immunol
, vol.173
, pp. 3383-3391
-
-
Raftery, M.J.1
Wieland, D.2
Gronewald, S.3
Kraus, A.A.4
Giese, T.5
Schonrich, G.6
-
28
-
-
4344584558
-
Heme oxygenase 1 expression induced by IL-10 requires STAT-3 and phosphoinositol-3 kinase and is inhibited by lipopolysaccharide
-
Ricchetti, G. A., L. M. Williams, and B. M. Foxwell. 2004. Heme oxygenase 1 expression induced by IL-10 requires STAT-3 and phosphoinositol-3 kinase and is inhibited by lipopolysaccharide. J. Leukoc. Biol. 76:719-726.
-
(2004)
J. Leukoc. Biol
, vol.76
, pp. 719-726
-
-
Ricchetti, G.A.1
Williams, L.M.2
Foxwell, B.M.3
-
29
-
-
0033523019
-
Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action
-
Riley, J. K., K. Takeda, S. Akira, and R. D. Schreiber. 1999. Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action. J. Biol. Chem. 274:16513-16521.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 16513-16521
-
-
Riley, J.K.1
Takeda, K.2
Akira, S.3
Schreiber, R.D.4
-
30
-
-
0036147258
-
Potent immunosuppressive activities of cytomegalovirus-encoded interleukin-10
-
Spencer, J. V., K. M. Lockridge, P. A. Barry, G. Lin, M. Tsang, M. E. Penfold, and T. J. Schall. 2002. Potent immunosuppressive activities of cytomegalovirus-encoded interleukin-10. J. Virol. 76:1285-1292.
-
(2002)
J. Virol
, vol.76
, pp. 1285-1292
-
-
Spencer, J.V.1
Lockridge, K.M.2
Barry, P.A.3
Lin, G.4
Tsang, M.5
Penfold, M.E.6
Schall, T.J.7
-
31
-
-
0034635414
-
Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40
-
Tomasec, P., V. M. Braud, C. Rickards, M. B. Powell, B. P. McSharry, S. Gadola, V. Cerundolo, L. K. Borysiewicz, A. J. McMichael, and G. W. Wilkinson. 2000. Surface expression of HLA-E, an inhibitor of natural killer cells, enhanced by human cytomegalovirus gpUL40. Science 287:1031.
-
(2000)
Science
, vol.287
, pp. 1031
-
-
Tomasec, P.1
Braud, V.M.2
Rickards, C.3
Powell, M.B.4
McSharry, B.P.5
Gadola, S.6
Cerundolo, V.7
Borysiewicz, L.K.8
McMichael, A.J.9
Wilkinson, G.W.10
-
32
-
-
0026089934
-
Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: Homology to Epstein-Barr virus open reading frame BCRFI
-
Vieira, P., R. de Waal-Malefyt, M. N. Dang, K. E. Johnson, R. Kastelein, D. F. Fiorentino, J. E. deVries, M. G. Roncarolo, T. R. Mosmann, and K. W. Moore. 1991. Isolation and expression of human cytokine synthesis inhibitory factor cDNA clones: homology to Epstein-Barr virus open reading frame BCRFI. Proc. Natl. Acad. Sci. USA 88:1172-1176.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 1172-1176
-
-
Vieira, P.1
de Waal-Malefyt, R.2
Dang, M.N.3
Johnson, K.E.4
Kastelein, R.5
Fiorentino, D.F.6
deVries, J.E.7
Roncarolo, M.G.8
Mosmann, T.R.9
Moore, K.W.10
-
33
-
-
0029117304
-
-
Wen, Z., Z. Zhong, and J. E. Darnell, Jr. 1995. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82:241-250.
-
Wen, Z., Z. Zhong, and J. E. Darnell, Jr. 1995. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82:241-250.
-
-
-
-
34
-
-
13944256944
-
Inhibition of integrin-linked kinase by a selective small molecule inhibitor, QLT0254, inhibits the PI3K/PKB/mTOR, Stat3, and FKHR pathways and tumor growth and enhances gemcitabine-induced apoptosis in human orthotopic primary pancreatic cancer xenografts
-
Yau, C. Y., J. J. Wheeler, K. L. Sutton, and D. W. Hedley. 2005. Inhibition of integrin-linked kinase by a selective small molecule inhibitor, QLT0254, inhibits the PI3K/PKB/mTOR, Stat3, and FKHR pathways and tumor growth and enhances gemcitabine-induced apoptosis in human orthotopic primary pancreatic cancer xenografts. Cancer Res. 65:1497-1504.
-
(2005)
Cancer Res
, vol.65
, pp. 1497-1504
-
-
Yau, C.Y.1
Wheeler, J.J.2
Sutton, K.L.3
Hedley, D.W.4
-
35
-
-
0035887654
-
IL-10 inhibits apoptosis of promyeloid cells by activating insulin receptor substrate-2 and phosphatidylinositol 3′-kinase
-
Zhou, J. H., S. R. Broussard, K. Strle, G. G. Freund, R. W. Johnson, R. Dantzer, and K. W. Kelley. 2001. IL-10 inhibits apoptosis of promyeloid cells by activating insulin receptor substrate-2 and phosphatidylinositol 3′-kinase. J. Immunol. 167:4436-4442.
-
(2001)
J. Immunol
, vol.167
, pp. 4436-4442
-
-
Zhou, J.H.1
Broussard, S.R.2
Strle, K.3
Freund, G.G.4
Johnson, R.W.5
Dantzer, R.6
Kelley, K.W.7
|