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Volumn 81, Issue 4, 2007, Pages 2083-2086

The cytomegalovirus homolog of interleukin-10 requires phosphatidylinositol 3-kinase activity for inhibition of cytokine synthesis in monocytes

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; JANUS KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 33846841130     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01655-06     Document Type: Article
Times cited : (34)

References (35)
  • 1
    • 0029762351 scopus 로고    scopus 로고
    • Human cytomegalovirus inhibits antigen presentation by a sequential multistep process
    • Ahn, K., A. Angulo, P. Ghazal, P. A. Peterson, Y. Yang, and K. Fruh. 1996. Human cytomegalovirus inhibits antigen presentation by a sequential multistep process. Proc. Natl. Acad. Sci. USA 93:10990-10995.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 10990-10995
    • Ahn, K.1    Angulo, A.2    Ghazal, P.3    Peterson, P.A.4    Yang, Y.5    Fruh, K.6
  • 2
    • 0141960095 scopus 로고    scopus 로고
    • A survival game of hide and seek: Cytomegaloviruses and MHC class I antigen presentation pathways
    • Basta, S., and J. R. Bennink. 2003. A survival game of hide and seek: cytomegaloviruses and MHC class I antigen presentation pathways. Viral Immunol. 16:231-242.
    • (2003) Viral Immunol , vol.16 , pp. 231-242
    • Basta, S.1    Bennink, J.R.2
  • 3
    • 0023841944 scopus 로고
    • Human cytomegalovirus encodes a glycoprotein homologous to MHC class-I antigens
    • Beck, S., and B. G. Barrell. 1988. Human cytomegalovirus encodes a glycoprotein homologous to MHC class-I antigens. Nature 331:269-272.
    • (1988) Nature , vol.331 , pp. 269-272
    • Beck, S.1    Barrell, B.G.2
  • 4
    • 3843104695 scopus 로고    scopus 로고
    • Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IκB kinase activity
    • Bhattacharyya, S., P. Sen, M. Wallet, B. Long, A. S. Baldwin, Jr., and R. Tisch. 2004. Immunoregulation of dendritic cells by IL-10 is mediated through suppression of the PI3K/Akt pathway and of IκB kinase activity. Blood 104:1100-1109.
    • (2004) Blood , vol.104 , pp. 1100-1109
    • Bhattacharyya, S.1    Sen, P.2    Wallet, M.3    Long, B.4    Baldwin Jr., A.S.5    Tisch, R.6
  • 5
    • 0001450002 scopus 로고    scopus 로고
    • Cytomegalovirus
    • B. N. Fields, D. M. Knipe, and P. M. Howley ed, 3rd ed. Lippincott-Raven Publishers, Philadelphia, PA
    • Britt, W. J., and C. A. Alford. 1996. Cytomegalovirus, p. 2493-2523. In B. N. Fields, D. M. Knipe, and P. M. Howley (ed.), Fields virology, 3rd ed. Lippincott-Raven Publishers, Philadelphia, PA.
    • (1996) Fields virology , pp. 2493-2523
    • Britt, W.J.1    Alford, C.A.2
  • 6
    • 33846832472 scopus 로고    scopus 로고
    • HCMV-encoded IL-10 alters dendritic cell functionality: A comprehensive comparison with cellular IL-10, abstr. 6.40. 29th Int
    • Reno, NV
    • Chang, W., N. Baumgarth, J. P. Greg, C. A. Baron, and P. A. Barry. 2004. HCMV-encoded IL-10 alters dendritic cell functionality: a comprehensive comparison with cellular IL-10, abstr. 6.40. 29th Int. Herpesvirus Workshop, Reno, NV.
    • (2004) Herpesvirus Workshop
    • Chang, W.1    Baumgarth, N.2    Greg, J.P.3    Baron, C.A.4    Barry, P.A.5
  • 7
    • 3543055705 scopus 로고    scopus 로고
    • Human cytomegalovirus-encoded interleukin-10 homolog inhibits maturation of dendritic cells and alters their functionality
    • Chang, W. L., N. Baumgarth, D. Yu, and P. A. Barry. 2004. Human cytomegalovirus-encoded interleukin-10 homolog inhibits maturation of dendritic cells and alters their functionality. J. Virol. 78:8720-8731.
    • (2004) J. Virol , vol.78 , pp. 8720-8731
    • Chang, W.L.1    Baumgarth, N.2    Yu, D.3    Barry, P.A.4
  • 8
    • 0030037906 scopus 로고    scopus 로고
    • Interleukin-10 stimulation of phosphatidylinositol 3-kinase and p70 S6 kinase is required for the proliferative but not the antiinflammatory effects of the cytokine
    • Crawley, J. B., L. M. Williams, T. Mander, F. M. Brennan, and B. M. Foxwell. 1996. Interleukin-10 stimulation of phosphatidylinositol 3-kinase and p70 S6 kinase is required for the proliferative but not the antiinflammatory effects of the cytokine. J. Biol. Chem. 271:16357-16362.
    • (1996) J. Biol. Chem , vol.271 , pp. 16357-16362
    • Crawley, J.B.1    Williams, L.M.2    Mander, T.3    Brennan, F.M.4    Foxwell, B.M.5
  • 10
    • 0034658024 scopus 로고    scopus 로고
    • Serine phosphorylation of STATs
    • Decker, T., and P. Kovarik. 2000. Serine phosphorylation of STATs. Oncogene 19:2628-2637.
    • (2000) Oncogene , vol.19 , pp. 2628-2637
    • Decker, T.1    Kovarik, P.2
  • 11
    • 0036701617 scopus 로고    scopus 로고
    • Diagnosis and treatment approaches of CMV infections in adult patients
    • de la Hoz, R. E., G. Stephens, and C. Sherlock. 2002. Diagnosis and treatment approaches of CMV infections in adult patients. J. Clin. Virol. 25(Suppl. 2):S1-S12.
    • (2002) J. Clin. Virol , vol.25 , Issue.SUPPL. 2
    • de la Hoz, R.E.1    Stephens, G.2    Sherlock, C.3
  • 12
    • 0026094306 scopus 로고
    • Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
    • de Waal Malefyt, R., J. Abrams, B. Bennett, C. G. Figdor, and J. E. de Vries. 1991. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174:1209-1220.
    • (1991) J. Exp. Med , vol.174 , pp. 1209-1220
    • de Waal Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    de Vries, J.E.5
  • 13
    • 0032779561 scopus 로고    scopus 로고
    • The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes
    • Donnelly, R. P., H. Dickensheets, and D. S. Finbloom. 1999. The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes. J. Interferon Cytokine Res. 19:563-573.
    • (1999) J. Interferon Cytokine Res , vol.19 , pp. 563-573
    • Donnelly, R.P.1    Dickensheets, H.2    Finbloom, D.S.3
  • 14
    • 0029118395 scopus 로고
    • IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes
    • Finbloom, D. S., and K. D. Winestock. 1995. IL-10 induces the tyrosine phosphorylation of tyk2 and Jak1 and the differential assembly of STAT1 alpha and STAT3 complexes in human T cells and monocytes. J. Immunol. 155:1079-1090.
    • (1995) J. Immunol , vol.155 , pp. 1079-1090
    • Finbloom, D.S.1    Winestock, K.D.2
  • 16
    • 0032077622 scopus 로고    scopus 로고
    • Immune evasion by cytomegalovirus - survival strategies of a highly adapted opportunist
    • Hengel, H., W. Brune, and U. H. Koszinowski. 1998. Immune evasion by cytomegalovirus - survival strategies of a highly adapted opportunist. Trends Microbiol. 6:190-197.
    • (1998) Trends Microbiol , vol.6 , pp. 190-197
    • Hengel, H.1    Brune, W.2    Koszinowski, U.H.3
  • 17
    • 0346373693 scopus 로고    scopus 로고
    • A novel viral transcript with homology to human interleukin-10 is expressed during latent human cytomegalovirus infection
    • Jenkins, C., A. Abendroth, and B. Slobedman. 2004. A novel viral transcript with homology to human interleukin-10 is expressed during latent human cytomegalovirus infection. J. Virol. 78:1440-1447.
    • (2004) J. Virol , vol.78 , pp. 1440-1447
    • Jenkins, C.1    Abendroth, A.2    Slobedman, B.3
  • 19
    • 0035992506 scopus 로고    scopus 로고
    • The family of IL-10-related cytokines and their receptors: Related, but to what extent?
    • Kotenko, S. V. 2002. The family of IL-10-related cytokines and their receptors: related, but to what extent? Cytokine Growth Factor Rev. 13:223-240.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 223-240
    • Kotenko, S.V.1
  • 20
    • 0034658583 scopus 로고    scopus 로고
    • Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes
    • Kotenko, S. V., and S. Pestka. 2000. Jak-Stat signal transduction pathway through the eyes of cytokine class II receptor complexes. Oncogene 19:2557-2565.
    • (2000) Oncogene , vol.19 , pp. 2557-2565
    • Kotenko, S.V.1    Pestka, S.2
  • 22
    • 0033197954 scopus 로고    scopus 로고
    • Inhibition of Kit expression by IL-4 and IL-10 in murine mast cells: Role of STAT6 and phosphatidylinositol 3′-kinase
    • Mirmonsef, P., C. P. Shelburne, C. Fitzhugh Yeatman II, H. J. Chong, and J. J. Ryan. 1999. Inhibition of Kit expression by IL-4 and IL-10 in murine mast cells: role of STAT6 and phosphatidylinositol 3′-kinase. J. Immunol. 163:2530-2539.
    • (1999) J. Immunol , vol.163 , pp. 2530-2539
    • Mirmonsef, P.1    Shelburne, C.P.2    Fitzhugh Yeatman II, C.3    Chong, H.J.4    Ryan, J.J.5
  • 24
    • 24044551995 scopus 로고    scopus 로고
    • PI3K/Akt/mTOR pathway as a target for cancer therapy
    • Morgensztern, D., and H. L. McLeod. 2005. PI3K/Akt/mTOR pathway as a target for cancer therapy. Anticancer Drugs 16:797-803.
    • (2005) Anticancer Drugs , vol.16 , pp. 797-803
    • Morgensztern, D.1    McLeod, H.L.2
  • 25
    • 0032481383 scopus 로고    scopus 로고
    • IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: Evidence for Stat3-dependent and -independent pathways
    • O'Farrell, A. M., Y. Liu, K. W. Moore, and A. L. Mui. 1998. IL-10 inhibits macrophage activation and proliferation by distinct signaling mechanisms: evidence for Stat3-dependent and -independent pathways. EMBO J. 17:1006-1018.
    • (1998) EMBO J , vol.17 , pp. 1006-1018
    • O'Farrell, A.M.1    Liu, Y.2    Moore, K.W.3    Mui, A.L.4
  • 26
    • 0033915344 scopus 로고    scopus 로고
    • Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase
    • Pahan, K., M. Khan, and I. Singh. 2000. Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase. J. Neurochem. 75:576-582.
    • (2000) J. Neurochem , vol.75 , pp. 576-582
    • Pahan, K.1    Khan, M.2    Singh, I.3
  • 27
    • 4344682020 scopus 로고    scopus 로고
    • Shaping phenotype, function, and survival of dendritic cells by cytomegalovirus-encoded IL-10
    • Raftery, M. J., D. Wieland, S. Gronewald, A. A. Kraus, T. Giese, and G. Schonrich. 2004. Shaping phenotype, function, and survival of dendritic cells by cytomegalovirus-encoded IL-10. J. Immunol. 173:3383-3391.
    • (2004) J. Immunol , vol.173 , pp. 3383-3391
    • Raftery, M.J.1    Wieland, D.2    Gronewald, S.3    Kraus, A.A.4    Giese, T.5    Schonrich, G.6
  • 28
    • 4344584558 scopus 로고    scopus 로고
    • Heme oxygenase 1 expression induced by IL-10 requires STAT-3 and phosphoinositol-3 kinase and is inhibited by lipopolysaccharide
    • Ricchetti, G. A., L. M. Williams, and B. M. Foxwell. 2004. Heme oxygenase 1 expression induced by IL-10 requires STAT-3 and phosphoinositol-3 kinase and is inhibited by lipopolysaccharide. J. Leukoc. Biol. 76:719-726.
    • (2004) J. Leukoc. Biol , vol.76 , pp. 719-726
    • Ricchetti, G.A.1    Williams, L.M.2    Foxwell, B.M.3
  • 29
    • 0033523019 scopus 로고    scopus 로고
    • Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action
    • Riley, J. K., K. Takeda, S. Akira, and R. D. Schreiber. 1999. Interleukin-10 receptor signaling through the JAK-STAT pathway. Requirement for two distinct receptor-derived signals for anti-inflammatory action. J. Biol. Chem. 274:16513-16521.
    • (1999) J. Biol. Chem , vol.274 , pp. 16513-16521
    • Riley, J.K.1    Takeda, K.2    Akira, S.3    Schreiber, R.D.4
  • 33
    • 0029117304 scopus 로고    scopus 로고
    • Wen, Z., Z. Zhong, and J. E. Darnell, Jr. 1995. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82:241-250.
    • Wen, Z., Z. Zhong, and J. E. Darnell, Jr. 1995. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82:241-250.
  • 34
    • 13944256944 scopus 로고    scopus 로고
    • Inhibition of integrin-linked kinase by a selective small molecule inhibitor, QLT0254, inhibits the PI3K/PKB/mTOR, Stat3, and FKHR pathways and tumor growth and enhances gemcitabine-induced apoptosis in human orthotopic primary pancreatic cancer xenografts
    • Yau, C. Y., J. J. Wheeler, K. L. Sutton, and D. W. Hedley. 2005. Inhibition of integrin-linked kinase by a selective small molecule inhibitor, QLT0254, inhibits the PI3K/PKB/mTOR, Stat3, and FKHR pathways and tumor growth and enhances gemcitabine-induced apoptosis in human orthotopic primary pancreatic cancer xenografts. Cancer Res. 65:1497-1504.
    • (2005) Cancer Res , vol.65 , pp. 1497-1504
    • Yau, C.Y.1    Wheeler, J.J.2    Sutton, K.L.3    Hedley, D.W.4
  • 35
    • 0035887654 scopus 로고    scopus 로고
    • IL-10 inhibits apoptosis of promyeloid cells by activating insulin receptor substrate-2 and phosphatidylinositol 3′-kinase
    • Zhou, J. H., S. R. Broussard, K. Strle, G. G. Freund, R. W. Johnson, R. Dantzer, and K. W. Kelley. 2001. IL-10 inhibits apoptosis of promyeloid cells by activating insulin receptor substrate-2 and phosphatidylinositol 3′-kinase. J. Immunol. 167:4436-4442.
    • (2001) J. Immunol , vol.167 , pp. 4436-4442
    • Zhou, J.H.1    Broussard, S.R.2    Strle, K.3    Freund, G.G.4    Johnson, R.W.5    Dantzer, R.6    Kelley, K.W.7


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