The selective 5-LOX inhibitor 11-keto-β-boswellic acid protects against myocardial ischemia reperfusion injury in rats: Involvement of redox and inflammatory cascades

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 386, Issue 9, 2013, Pages 823-833

  Elshazly, Shimaa M ^a   Abd El Motteleb, Dalia M ^b   Nassar, Noha N ^c  

^a Zagazig University   (Egypt)

^b ZAGAZIG UNIVERSITY   (Egypt)

^c CAIRO UNIVERSITY   (Egypt)

Author keywords

11 keto BA; 5 LOX; ICAM 1; Myocardial I R; NF B; Nrf2

Indexed keywords

11 OXO BETA BOSWELLIC ACID; 3 NITROTYROSINE; ARACHIDONATE 5 LIPOXYGENASE; CASPASE 3; CYCLOOXYGENASE 2; DNA; GLUTATHIONE PEROXIDASE; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; LACTATE DEHYDROGENASE; MYELOPEROXIDASE; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DNA FRAGMENTATION; DOSE RESPONSE; ENZYME ACTIVITY; HEART; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IMMUNOHISTOCHEMISTRY; INFLAMMATION; LACTATE DEHYDROGENASE BLOOD LEVEL; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MALE; NONHUMAN; OXIDATION REDUCTION REACTION; RAT; REPERFUSION INJURY;

ANIMALS; ARACHIDONATE 5-LIPOXYGENASE; CARDIOTONIC AGENTS; CASPASE 3; CYCLOOXYGENASE 2; DNA FRAGMENTATION; GENE EXPRESSION REGULATION; GLUTATHIONE PEROXIDASE; HEME OXYGENASE (DECYCLIZING); INTERCELLULAR ADHESION MOLECULE-1; LIPOXYGENASE INHIBITORS; MALE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NF-E2-RELATED FACTOR 2; NF-KAPPA B; OXIDATION-REDUCTION; PEROXIDASE; RATS; RATS, WISTAR; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE;

EID: 84883254395     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-013-0885-9     Document Type: Article

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