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Angewandte Chemie - International Edition

Volumn 52, Issue 36, 2013, Pages 9529-9533

Cyplecksins are covalent inhibitors of the pleckstrin homology domain of cytohesin

(9) Hussein, Mohamed a Bettio, Martina a Schmitz, Anton a Hannam, Jeffrey S a Theis, Julian a Mayer, Günter a Dosa, Stefan a Gütschow, Michael a Famulok, Michael a

a UNIVERSITY OF BONN (Germany)

Author keywords

aptamers; Cyplecksins; cytohesin; drug development; inhibitors

Indexed keywords

APTAMERS; BIOLOGICAL FUNCTIONS; CYPLECKSINS; CYTOHESIN; DRUG DEVELOPMENT; GUANINE NUCLEOTIDE EXCHANGE FACTORS; PLECKSTRIN HOMOLOGY DOMAINS; POTENTIAL DRUG TARGETS;

CHEMICAL REACTIONS; CORROSION INHIBITORS;

CHEMISTRY;

CYPLECKSIN 1; CYTOHESIN 1; CYTOHESIN-1; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PROTEIN; PYRIMIDINONE DERIVATIVE;

APTAMERS; ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CYPLECKSINS; CYTOHESIN; DRUG ANTAGONISM; DRUG DEVELOPMENT; DRUG SCREENING; HELA CELL; HIGH THROUGHPUT SCREENING; HUMAN; INHIBITORS; PROTEIN MOTIF; TWO DIMENSIONAL GEL ELECTROPHORESIS;

APTAMERS; CYPLECKSINS; CYTOHESIN; DRUG DEVELOPMENT; INHIBITORS;

AMINO ACID MOTIFS; BINDING SITES; DRUG EVALUATION, PRECLINICAL; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GREEN FLUORESCENT PROTEINS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HELA CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MOLECULAR STRUCTURE; PROTEINS; PYRIMIDINONES;

EID: 84883248121 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201302207 Document Type: Article

Times cited : (8)

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