SCOPUS 정보 검색 플랫폼

Angewandte Chemie - International Edition

Volumn 51, Issue 35, 2012, Pages 8699-8700

Reversible covalent inhibition of a protein target

(2) Lee, Chang Uk a Grossmann, Tom N a

a CHEMICAL GENOMICS CENTRE OF THE MAX PLANCK SOCIETY (Germany)

Author keywords

cysteine; drug design; inhibitors; Michael addition; reversibility

Indexed keywords

CYSTEINE; DRUG DESIGN; ELECTRON-DEFICIENT; ELECTROPHILES; HIGH-AFFINITY BINDERS; KINASE INHIBITORS; MICHAEL ACCEPTORS; MICHAEL ADDITIONS; PROTEIN MODIFICATIONS; PROTEIN TARGETS; REVERSIBILITY; REVERSIBLE ADDITION;

AMINO ACIDS; CORROSION INHIBITORS;

ADDITION REACTIONS;

CYSTEINE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; S6 KINASE;

ARTICLE; BINDING SITE; CHEMISTRY; DRUG DESIGN; METABOLISM; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYSTEINE; DRUG DESIGN; PROTEIN KINASE INHIBITORS; PROTEIN KINASES; PROTEIN STRUCTURE, TERTIARY; RIBOSOMAL PROTEIN S6 KINASES, 90-KDA;

EID: 84865407060 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201203341 Document Type: Article

Times cited : (64)

References (10)

1
- 79953314480
- J. Singh, R. C. Petter, T. A. Baillie, A. Whitty, Nat. Rev. Drug Discovery 2011, 10, 307-317.
- (2011) Nat. Rev. Drug Discovery , vol.10 , pp. 307-317
- Singh, J.¹ Petter, R.C.² Baillie, T.A.³ Whitty, A.⁴

2
- 79953314978
- B. K. Park, A. Boobis, S. Clarke, C. E. P. Goldring, D. Jones, J. G. Kenna, C. Lambert, H. G. Laverty, D. J. Naisbitt, S. Nelson, D. A. Nicoll-Griffith, R. S. Obach, P. Routledge, D. A. Smith, D. J. Tweedie, N. Vermeulen, D. P. Williams, I. D. Wilson, T. A. Baillie, Nat. Rev. Drug Discovery 2011, 10, 292-306
- (2011) Nat. Rev. Drug Discovery , vol.10 , pp. 292-306
- Park, B.K.¹ Boobis, A.² Clarke, S.³ Goldring, C.E.P.⁴ Jones, D.⁵ Kenna, J.G.⁶ Lambert, C.⁷ Laverty, H.G.⁸ Naisbitt, D.J.⁹ Nelson, S.¹⁰ Nicoll-Griffith, D.A.¹¹ Obach, R.S.¹² Routledge, P.¹³ Smith, D.A.¹⁴ Tweedie, D.J.¹⁵ Vermeulen, N.¹⁶ Williams, D.P.¹⁷ Wilson, I.D.¹⁸ Baillie, T.A.¹⁹

3
- 60449094541
- A. J. T. Smith, X. Y. Zhang, A. G. Leach, K. N. Houk, J. Med. Chem. 2009, 52, 225-233.
- (2009) J. Med. Chem. , vol.52 , pp. 225-233
- Smith, A.J.T.¹ Zhang, X.Y.² Leach, A.G.³ Houk, K.N.⁴

4
- 84859845948
- I. M. Serafimova, M. A. Pufall, S. Krishnan, K. Duda, M. S. Cohen, R. L. Maglathlin, J. M. McFarland, R. M. Miller, M. Frödin, J. Taunton, Nat. Chem. Biol. 2012, 8, 471-476.
- (2012) Nat. Chem. Biol. , vol.8 , pp. 471-476
- Serafimova, I.M.¹ Pufall, M.A.² Krishnan, S.³ Duda, K.⁴ Cohen, M.S.⁵ Maglathlin, R.L.⁶ McFarland, J.M.⁷ Miller, R.M.⁸ Frödin, M.⁹ Taunton, J.¹⁰

5
- 57749188299
- J. M. Zhang, P. L. Yang, N. S. Gray, Nat. Rev. Cancer 2009, 9, 28-39.
- (2009) Nat. Rev. Cancer , vol.9 , pp. 28-39
- Zhang, J.M.¹ Yang, P.L.² Gray, N.S.³

6
- 77955314699
- J. Singh, R. C. Petter, A. F. Kluge, Curr. Opin. Chem. Biol. 2010, 14, 475-480.
- (2010) Curr. Opin. Chem. Biol. , vol.14 , pp. 475-480
- Singh, J.¹ Petter, R.C.² Kluge, A.F.³

7
- 33644826759
- G. Lee, D. E. Piper, Z. L. Wang, J. Anzola, J. Powers, N. Walker, Y. Li, J. Mol. Biol. 2006, 357, 1051-1057
- (2006) J. Mol. Biol. , vol.357 , pp. 1051-1057
- Lee, G.¹ Piper, D.E.² Wang, Z.L.³ Anzola, J.⁴ Powers, J.⁵ Walker, N.⁶ Li, Y.⁷

8
- 79851480621
- R. J. Patch, L. L. Searle, A. J. Kim, D. Y. D. De, X. Z. Zhu, H. B. Askari, J. C. O'Neill, M. C. Abad, D. Rentzeperis, J. Y. Liu, M. Kemmerer, L. Lin, J. Kasturi, J. G. Geisler, J. M. Lenhard, M. R. Player, M. D. Gaul, J. Med. Chem. 2011, 54, 788-808.
- (2011) J. Med. Chem. , vol.54 , pp. 788-808
- Patch, R.J.¹ Searle, L.L.² Kim, A.J.³ De, D.Y.D.⁴ Zhu, X.Z.⁵ Askari, H.B.⁶ O'Neill, J.C.⁷ Abad, M.C.⁸ Rentzeperis, D.⁹ Liu, J.Y.¹⁰ Kemmerer, M.¹¹ Lin, L.¹² Kasturi, J.¹³ Geisler, J.G.¹⁴ Lenhard, J.M.¹⁵ Player, M.R.¹⁶ Gaul, M.D.¹⁷

9
- 0006642161
- R. B. Pritchard, C. E. Lough, D. J. Currie, H. L. Holmes, Can. J. Chem. 1968, 46, 775-781.
- (1968) Can. J. Chem. , vol.46 , pp. 775-781
- Pritchard, R.B.¹ Lough, C.E.² Currie, D.J.³ Holmes, H.L.⁴

10
- 19744364796
- M. S. Cohen, C. Zhang, K. M. Shokat, J. Taunton, Science 2005, 308, 1318-1321.
- (2005) Science , vol.308 , pp. 1318-1321
- Cohen, M.S.¹ Zhang, C.² Shokat, K.M.³ Taunton, J.⁴

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.