Constituents from Terminalia species increase PPARα and PPARγ levels and stimulate glucose uptake without enhancing adipocyte differentiation

Journal of Ethnopharmacology

Volumn 149, Issue 2, 2013, Pages 490-498

  Yang, Min Hye ^a   Vasquez, Yelkaira ^a   Ali, Zulfiqar ^a   Khan, Ikhlas A ^a,b   Khan, Shabana I ^a,b  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Adipogenesis; Gallotannin; Glucose uptake stimulation; PPAR and PPAR signaling; Terminalia bellerica; Terminalia chebula

Indexed keywords

1,2,3,4,6 PENTA O GALLOYL BETA GLUCOSE; 1,2,3,6 TETRA O GALLOYL BETA GLUCOSE; 2,3,6 TRI O GALLOYL BETA GLUCOSE; CHEBULAGIC ACID; CORILAGIN; LUCIFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; ROSIGLITAZONE; TANNIN DERIVATIVE; TERMINALIA BELLIRICA EXTRACT; TERMINALIA CHEBULA EXTRACT; UNCLASSIFIED DRUG;

ADIPOCYTE; ADIPOGENESIS; ANALYSIS; ANIMAL CELL; ARTICLE; AYURVEDA; CELL DIFFERENTIATION; CELL STRAIN 3T3; CELL STRAIN HEPG2; CONTROLLED STUDY; DIABETES MELLITUS; DRUG ANTAGONISM; DRUG INDICATION; FRUIT; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN EXPRESSION; TERMINALIA BELLIRICA; TERMINALIA CHEBULA; WESTERN BLOTTING;

COMBRETACEAE; TERMINALIA; TERMINALIA BELLIRICA; TERMINALIA CHEBULA; TETRA;

ADIPOGENESIS; GALLOTANNIN; GLUCOSE UPTAKE STIMULATION; PPARΑ AND PPARΓ SIGNALING; TERMINALIA BELLERICA; TERMINALIA CHEBULA;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; CELL DIFFERENTIATION; GLUCOSE; HEP G2 CELLS; HUMANS; HYDROLYZABLE TANNINS; LIPID METABOLISM; MICE; PLANT EXTRACTS; PPAR ALPHA; PPAR GAMMA; TERMINALIA;

EID: 84883172602     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.07.003     Document Type: Article

References (47)

1. R.N. Bergman, and M. Ader Free fatty acids and pathogenesis of type 2 diabetes mellitus Trends in Endocrinology and Metabolism 11 2000 351 356
2. J.F. Blicklé, and J.W.F. Elte Thiazolidinediones for the treatment of type 2 diabetes European Journal of Internal Medicine 18 2007 18 25
3. O. Braissant, and W. Wahli Differential expression of peroxisome proliferator-activated receptor-α, -β, and -γ during rat embryonic development Endocrinology 139 1998 2748 2754
4. M.C. Carmona, K. Louche, M. Nibbelink, B. Prunet, A. Bross, M. Desbazeille, C. Dacquet, P. Renard, L. Casteilla, and L. Pénicaud Fenofibrate prevents Rosiglitazone-induced body weight gain in ob/ob mice International Journal of Obesity 29 2005 864 871
5. A. Chawla, E.J. Schwarz, D.D. Dimaculangan, and M.A. Lazar Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation Endocrinology 135 1994 798 800
6. Q.C. Chen, W.Y. Zhang, W. Jin, I.S. Lee, B.S. Min, H.J. Jung, M. Na, S. Lee, and K. Bae Flavonoids and isoflavonoids from Sophorae flos improve glucose uptake in vitro Planta Medica 76 2010 79 81
7. P. Cornelius, O.A. MacDougald, and M.D. Lane Regulation of adipocyte development Annual Review of Nutrition 14 1994 99 129
8. C.J. de Souza, M. Eckhardt, K. Gagen, M. Dong, W. Chen, D. Laurent, and B.F. Burkey Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance Diabetes 50 2001 1863 1871
9. R.A. Defronzo Pharmacologic therapy for type 2 diabetes mellitus Annals of Internal Medicine 131 1999 281 303
10. R.A. DeFronzo, and E. Ferrannini Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease Diabetes Care 14 1991 173 194
11. B. Desvergne, and W. Wahli Peroxisome proliferator-activated receptors: nuclear control of metabolism Endocrine Reviews 20 1999 649 688
12. X.K. Fang, J. Gao, and D.N. Zhu Kaempferol and quercetin isolated from Euonymus alatus improve glucoe uptake of 3T3-L1 cells without adipogenesis activity Life Sciences 82 2008 615 622
13. C. Flevét, J.C. Fruchart, and B. Staels PPARα and PPARγ dual agonists for the treatment of type 2 diabetes and the metabolic syndrome Current Opinion in Pharmacology 6 2006 606 614
14. G. Fruhbeck, J. Gomez-Ambrosi, F.J. Muruzabal, and M.A. Burrell The adipocyte: a model for integration of endocrine and metabolic signaling in energy metabolism regulation American Journal of Physiology: Endocrinology and Metabolism 280 2001 E827 E847
15. H. Gao, Y.N. Huang, P.Y. Xu, and J Kawabata Inhibitory effect on α-glucosidase by the fruits of Terminalia chebula Retz Food Chemistry 105 2007 628 634
16. J.K. Grover, S. Yadav, and V. Vats Medicinal plants of India with anti-diabetic potential Journal of Ethnopharmacology 81 2002 81 100
17. Y. Guan, C. Hao, D.R. Cha, R. Rao, W. Lu, D.E. Kohan, M.A. Magnuson, R. Redha, Y. Zhang, and M.D. Breyer Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption Nature Medicine 11 2005 861 866
18. B.R. Henke Peroxisome proliferator-activated receptor α/γ dual agonists for the treatment of type 2 diabetes Journal of Medicinal Chemistry 47 2004 4118 4127
19. T.H. Huang, A.W. Teoh, B.L. Lin, D.S. Lin, and B. Roufogalis The role of herbal PPAR modulators in the treatment of cardiometabolic syndrome Pharmacological Research 60 2009 195 206
20. International Diabetes Federation, 2009. Diabetes Atlas. Brussels, Belgium.
21. M.S. Jaradat, B. Wongsud, S. Phornchirasilp, S.M. Rangwala, G. Shams, M. Sutton, K.J. Romstedt, D.J. Noonan, and D.R. Feller Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H2 synthases by ibuprofen, naproxen, and indomethacin Biochemical Pharmacology 62 2001 1587 1595
22. M. Jung, M. Park, H.C. Lee, Y.H. Kang, E.S. Kang, and S.K. Kim Anti-diabetic agents from medicinal plants Current Medicinal Chemistry 13 2006 1203 1218
23. R. Kasturi, and V.C. Joshi Hormonal regulation of stearoyl coenzyme A desaturase activity and lipogenesis during adipose conversion 3T3-L1 cells Journal of Biological Chemistry 257 1982 12224 12230
24. R.F. Kletzien, S.D. Clarke, and R.G. Ulrich Enhancement of adipocyte differentiation by an insulin-sensitizing agent Molecular Pharmacology 41 1992 393 398
25. S. Kumanyika, R.W. Jeffery, A. Morabia, C. Ritenbaugh, and V.J. Antipatis Obesity prevention: the case for action. Public Health Approaches to the Prevention of Obesity (PHAPO) working group of the International Obesity Task Force (IOTF) International Journal of Obesity and Related Metabolic Disorders 26 2002 425 436
26. Y. Li, J. Kim, J. Li, F. Liu, X. Liu, K. Himmeldirk, Y. Rena, T.E. Wagnere, and X. Chen Natural anti-diabetic compound 1,2,3,4,6-penta-O-galloyl-d- glucopyranose binds to insulin receptor and activates insulin-mediated glucose transport signaling pathway Biochemical and Biophysical Research Communications 336 2005 430 437
27. A. Majumdar Ayurveda: the ancient science of healing 2nd ed. 2004 MacMillan India Ltd. New Delhi, India
28. F. Malekzadeha, H. Ehsanifara, M. Shahamatb, M. Levinb, and R.R. Colwellb Antibacterial activity of black myrobalan (Terminalia chebula Retz) against Helicobacter pylori International Journal of Antimicrobial Agents 18 2001 85 88
29. C.S. Mizuno, G. Ma, S. Khan, A. Patny, M.A. Avery, and A.M. Rimando Design, synthesis, biological evaluation and docking studies of pterostilbene analogs inside PPARα Bioorganic and Medicinal Chemistry 16 2008 3800 3808
30. S.V. Nampoothiri, A. Prathapan, O.L. Cherian, K.G. Raghu, V.V. Venugopalan, and A. Sundaresan In vitro antioxidant and inhibitory potential of Terminalia bellerica and Emblica officinalis fruits against LDL oxidation and key enzymes linked to type 2 diabetes Food and Chemical Toxicology 49 2011 125 131
31. J.M. Olefsky Treatment of insulin resistance with peroxisome proliferator-activated receptor γ agonists The Journal of Clinical Investigation 106 2000 467 472
32. J.M. Olefsky, and A.R. Saltiel PPARγ and the treatment of insulin resistance Trends in Endocrinology and Metabolism 9 2000 362 368
33. H.J Pan, Y. Lin, Y.E. Chen, D.E. Vance, and E.H. Leiter Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism Vascular Pharmacology 45 2006 65 71
34. D.K. Patel, R. Kumar, D. Laloo, and S. Hemalatha Natural medicines from plant source used for therapy of diabetes mellitus: an overview of its pharmacological aspects Asian Pacific Journal of Tropical Disease 2 2012 239 250
35. B. Pfundstein, S.K. El Desouky, W.E. Hull, R. Haubner, G. Erben, and R.W. Owen Polyphenolic compounds in the fruits of Egyptian medicinal plants (Terminalia bellerica, Terminalia chebula and Terminalia horrida): characterization, quantitation and determination of antioxidant capacities Phytochemistry 71 2010 1132 1148
36. R.C. Rebeiro, P.J. Kushner, and J.D. Baxter The nuclear hormone receptor gene superfamily Annual Review of Medicine 46 1995 443 453
37. Ribon, V., Johnson, J.H., Camp, H.S., Saltiel, A.R., 1998. Thiazolidinediones and insulin resistance: peroxisome proliferator-activated receptor γ activation stimulates expression of the CAP gene. Proceedings of National Academy of Sciences 95, pp. 14751-14756.
38. M.C. Sabu, and C.R. Kuttan Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property Journal of Ethnopharmacology 81 2002 155 160
39. A.R. Saltiel, and C.R. Kahn Insulin signaling and the regulation of glucose and lipid metabolism Nature 414 2001 799 806
40. P. Shen, M.H. Liu, T.Y. Ng, Y.H. Chan, and E.L. Yong Differential effects of isoflavones, from Astragalus membranaceus and Pueraria thomsonii, on the activation of PPARα, PPARγ, and adipocyte differentiation in vitro The Journal of Nutrition 136 2006 899 905
41. B. Staels, and J.C. Fruchart Therapeutic roles of peroxisome proliferator-activated receptor agonists Diabetes 54 2005 2460 2470
42. S.R. Tafuri Troglitazone enhances differentiation, basal glucose uptake, and Glut1 protein levels in 3T3-L1 adipocytes Endocrinology 137 1996 4706 4712
43. P. Tontonoz, E. Hu, and B.M. Spiegelman Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor Cell 79 1994 1147 1156
44. N. Verma, A.P. Singh, G. Amresh, P.K. Sahub, A. Singha, and N. Mishrab Review on wonderful and miraculous triphala Journal of Pharmacy Research 4 2011 690 694
45. D.R. Whiting, L. Guariguata, C. Weil, and J. Shaw IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030 Diabetes Research and Clinical Practice 94 2011 311 321
46. J. Xu, M. Ma, and W.M. Purcell Characterization of some cytotoxic endpoints using rat liver and HepG2 spheroids as in vitro models and their application in hepatotoxicity studies. I. Glucose metabolism and enzyme release as cytotoxic markers Toxicology and Applied Pharmacology 189 2003 100 111
47. J.M. Ye, P.J. Doyle, M.A. Iglesias, D.G. Watson, G.J. Cooney, and E.W. Kraegen Peroxisome proliferator-activated receptor (PPAR)-α activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: comparison with PPAR-γ activation Diabetes 54 2001 3358 3370