The chemokine CXCL6 restricts human trophoblast cell migration and invasion by suppressing MMP-2 activity in the first trimester

Human Reproduction

Volumn 28, Issue 9, 2013, Pages 2350-2362

  Zhang, H ^a   Hou, L ^a   Li, C M ^a   Zhang, W Y ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

chemokine; CXCL6; invasion; migration; trophoblast cells

Indexed keywords

CHEMOKINE RECEPTOR CXCR1; CHEMOKINE RECEPTOR CXCR2; GELATINASE A; GELATINASE B; GRANULOCYTE CHEMOTACTIC PROTEIN 2; RNA;

ARTICLE; CELL ASSAY; CELL INVASION; CELL PROLIFERATION; CHORION VILLUS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPLANT; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MIGRATION INHIBITION; NORMAL HUMAN; PLACENTA; PREGNANCY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; SECOND TRIMESTER PREGNANCY; SUPERNATANT; THIRD TRIMESTER PREGNANCY; TROPHOBLAST; ZYMOGRAPHY;

CHEMOKINE; CXCL6; INVASION; MIGRATION; TROPHOBLAST CELLS;

CELL LINE; CELL MOVEMENT; CELLS, CULTURED; CHEMOKINE CXCL6; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; MATRIX METALLOPROTEINASE 2; PLACENTA; PLACENTATION; PREGNANCY; PREGNANCY TRIMESTER, FIRST; PREGNANCY TRIMESTER, SECOND; PREGNANCY TRIMESTER, THIRD; RECOMBINANT PROTEINS; RNA, MESSENGER; TISSUE CULTURE TECHNIQUES; TROPHOBLASTS; UP-REGULATION;

EID: 84883170960     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/det258     Document Type: Article

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