Role of chemokines in the endometrium and in embryo implantation

Current Opinion in Obstetrics and Gynecology

Volumn 19, Issue 3, 2007, Pages 266-272

  Hannan, Natalie J ^a,b   Salamonsen, Lois A ^a  

^a MONASH UNIVERSITY   (Australia)

^b NONE   (Australia)

Author keywords

Chemokines; Endometrium; Implantation; Placentation

Indexed keywords

CHEMOKINE; CHEMOKINE RECEPTOR CXCR6; CXCL1 CHEMOKINE; CXCL11 CHEMOKINE; CXCL14 CHEMOKINE; CXCL9 CHEMOKINE; EOTAXIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; MONOCYTE CHEMOTACTIC PROTEIN 4; RANTES; SECONDARY LYMPHOID TISSUE CHEMOKINE; STROMAL CELL DERIVED FACTOR 1;

BLASTOCYTE; CELL MIGRATION; CHORION VILLUS; CYTOTROPHOBLAST; DECIDUA; DECIDUALIZATION; EMBRYO; ENDOMETRIUM; HUMAN; MYOMETRIUM; NIDATION; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SYNCYTIOTROPHOBLAST; TROPHOBLAST; UTERUS BLOOD FLOW;

CELL MOVEMENT; CHEMOKINES; EMBRYO IMPLANTATION; ENDOMETRIUM; FEMALE; HUMANS; LEUKOCYTES; PLACENTATION; PREGNANCY; RECEPTORS, CHEMOKINE; TROPHOBLASTS;

EID: 34248376053     PISSN: 1040872X     EISSN: None     Source Type: Journal    
DOI: 10.1097/GCO.0b013e328133885f     Document Type: Review

References (50)

1. Dominguez F, Pellicer A, Simon C. Paracrine dialogue in implantation. Mol Cell Endocrinol 2002; 186:175-181.
2. Pijnenborg R, Dixon G, Robertson WB, Brosens I. Trophoblastic invasion of human decidua from 8 to 18 weeks of pregnancy. Placenta 1980; 1:3-19.
3. Shih JC, Chien CL, Ho HN, et al. Stellate transformation of invasive trophoblast: a distinct phenotype of trophoblast that is involved in decidual vascular remodelling and controlled invasion during pregnancy. Hum Reprod 2006; 21:1299-1304. This important study demonstrates the various remodelling effects that the trophoblast has on the maternal spiral arteries.
4. Drake PM, Red-Horse K, Fisher SJ. Chemokine expression and function at the human maternal-fetal interface. Rev Endocr Metab Disord 2002; 3:159-165.
5. Damsky CH, Fitzgerald ML, Fisher SJ. Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vivo. J Clin Invest 1992; 89:210-222.
6. Bacon K, Baggiolini M, Broxmeyer H, et al. Chemokine/chemokine receptor nomenclature. J Interferon Cytokine Res 2002; 22:1067-1068.
7. Kunkel EJ, Butcher EC. Plasma-cell homing. Nat Rev Immunol 2003; 3:822-829.
8. Greenlee KJ, Corry DB, Engler DA, et al. Proteomic identification of in vivo substrates for matrix metalloproteinases 2 and 9 reveals a mechanism for resolution of inflammation. J Immunol 2006; 177:7312-7321. This important study demonstrates the regulation of chemokine bioactivity through proteolytic processing.
9. Proost P, Struyf S, Van Damme J. Natural posttranslational modifications of chemokines. Biochem Soc Trans 2006; 34:997-1001. This interesting review discusses the importance of post-translational processing in the regulation of chemokine bioactivity.
10. Ryu OH, Choi SJ, Firatli E, et al. Proteolysis of macrophage inflammatory protein-1alpha isoforms LD78beta and LD78alpha by neutrophil-derived serine proteases. J Biol Chem 2005; 280:17415-17421.
11. Chapman GA, Moores KE, Gohil J, et al. The role of fractalkine in the recruitment of monocytes to the endothelium. Eur J Pharmacol 2000; 392:189-195.
12. Cross AK, Woodroofe MN. Chemokine modulation of matrix metalloproteinase and TIMP production in adult rat brain microglia and a human microglial cell line in vitro. Glia 1999; 28:183-189.
13. Vitale S, Schmid-Alliana A, Breuil V, et al. Soluble fractalkine prevents monocyte chemoattractant protein-1-induced monocyte migration via inhibition of stress-activated protein kinase 2/p38 and matrix metalloproteinase activities. J Immunol 2004; 172:585-592.
14. Hannan NJ, Jones RL, White CA, Salamonsen LA. The chemokines, CX3CL1, CCL14, and CCL4, promote human trophoblast migration at the feto-maternal interface. Biol Reprod 2006; 74:896-904. This significant study demonstrates the presence and effects of chemokine-receptor signalling at the maternal-foetal interface, with particular emphasis on trophoblast migration.
15. Zhou C, Borillo J, Wu J, et al. Ovarian expression of chemokines and their receptors. J Reprod Immunol 2004; 63:1-9.
16. Jones RL, Hannan NJ, Kaitu'u TJ, et al. Identification of chemokines important for leukocyte recruitment to the human endometrium at the times of embryo implantation andmenstruation. J Clin Endocrinol Metab 2004; 89:6155-6167.
17. Hannan NJ, Jones RL, Critchley HO, et al. Coexpression of fractalkine and its receptor in normal human endometrium and in endometrium from users of progestin-only contraception supports a role for fractalkine in leukocyte recruitment and endometrial remodeling. J Clin Endocrinol Metab 2004; 89:6119-6129.
18. Simon C, Caballero-Campo P, Garcia-Velasco JA, Pellicer A. Potential implications of chemokines in reproductive function: an attractive idea. J Reprod Immunol 1998; 38:169-193.
19. Garcia-Velasco JA, Arici A. Chemokines and human reproduction. Fertil Steril 1999; 71:983-993.
20. Dowsland MH, Harvey JR, Lennard TW, et al. Chemokines and breast cancer: a gateway to revolutionary targeted cancer treatments? Curr Med Chem 2003; 10:579-592.
21. Bulmer JN, Longfellow M, Ritson A. Leukocytes and resident blood cells in endometrium. Ann N Y Acad Sci 1991; 622:57-68.
22. King A, Burrows T, Verma S, et al. Human uterine lymphocytes. Hum Reprod Update 1998; 4:480-485.
23. Salamonsen LA, Zhang J, Brasted M. Leukocyte networks and human endometrial remodelling. J Reprod Immunol 2002; 57:95-108.
24. Trundley A, Moffett A. Human uterine leukocytes and pregnancy. Tissue Antigens 2004; 63:1-12.
25. Salamonsen LA, Woolley DE. Menstruation: induction by matrix metalloproteinases and inflammatory cells. J Reprod Immunol 1999; 44:1-27.
26. Hampton AL, Rogers PA, Affandi B, Salamonsen LA. Expression of the chemokines, monocyte chemotactic protein (MCP)-1 and MCP-2 in endometrium of normal women and Norplant users, does not support a central role in macrophage infiltration into endometrium. J Reprod Immunol 2001; 49:115-132.
27. Akiyama M, Okabe H, Takakura K, et al. Expression of macrophage inflammatory protein-1alpha (MIP-1alpha) in human endometrium throughout the menstrual cycle. Br J Obstet Gynaecol 1999; 106:725-730.
28. Zhang J, Lathbury LJ, Salamonsen LA. Expression of the chemokine eotaxin and its receptor, CCR3, in human endometrium. Biol Reprod 2000; 62:404-411.
29. Caballero-Campo P, Dominguez F, Coloma J, et al. Hormonal and embryonic regulation of chemokines IL-8, MCP-1 and RANTES in the human endometrium during the window of implantation. Mol Hum Reprod 2002; 8:375-384.
30. Kayisli UA, Mahutte NG, Arici A. Uterine chemokines in reproductive physiology and pathology. Am J Reprod Immunol 2002; 47:213-221.
31. Critchley HO, Kelly RW, Lea RG, et al. Sex steroid regulation of leukocyte traffic in human decidua. Hum Reprod 1996; 11:2257-2262.
32. Jones RL, Kelly RW, Critchley HO. Chemokine and cyclooxygenase-2 expression in human endometrium coincides with leukocyte accumulation. Hum Reprod 1997; 12:1300-1306.
33. Critchley HO, Kelly RW, Kooy J. Perivascular location of a chemokine interleukin-8 in human endometrium: a preliminary report. Hum Reprod 1994; 9:1406-1409.
34. Dominguez F, Galan A, Martin JJ, et al. Hormonal and embryonic regulation of chemokine receptors CXCR1, CXCR4, CCR5 and CCR2B in the human endometrium and the human blastocyst. Mol Hum Reprod 2003; 9:189-198.
35. Dimitriadis E, White CA, Jones RL, Salamonsen LA. Cytokines, chemokines and growth factors in endometrium related to implantation. Hum Reprod Update 2005; 11:613-630.
36. Hanna J, Goldman-Wohl D, Hamani Y, et al. Decidual NK cells regulate key developmental processes at the human fetal-maternal interface. Nat Med 2006; 12:1065-1074. This excellent study highlights the essential roles played by uNK cells at the human maternal-foetal interface.
37. Sato Y, Higuchi T, Yoshioka S, et al. Trophoblasts acquire a chemokine receptor, CCR1, as they differentiate towards invasive phenotype. Development 2003; 130:5519-5532.
38. Red-Horse K, Drake PM, Gunn MD, Fisher SJ. Chemokine ligand and receptor expression in the pregnant uterus: reciprocal patterns in complementary cell subsets suggest functional roles. Am J Pathol 2001; 159:2199-2213.
39. Meter RA, Wira CR, Fahey JV. Secretion of monocyte chemotactic protein-1 by human uterine epithelium directs monocyte migration in culture. Fertil Steril 2005; 84:191-201.
40. Lockwood CJ, Matta P, Krikun G, et al. Regulation of monocyte chemoattractant protein-1 expression by tumor necrosis factor-alpha and interleukin-1beta in first trimester human decidual cells: implications for preeclampsia. Am J Pathol 2006; 168:445-452. This interesting study demonstrates the importance of controlled macrophage recruitment during early placentation.
41. van den Heuvel MJ, Xie X, Tayade C, et al. A review of trafficking and activation of uterine natural killer cells. Am J Reprod Immunol 2005; 54:322-331.
42. - NK cells into decidua by way of expressing and secreting of CXCL12/stromal cell-derived factor 1. J Immunol 2005; 175:61-68.
43. Genbacev OD, Prakobphol A, Foulk RA, et al. Trophoblast L-selectin-mediated adhesion at the maternal-fetal interface. Science 2003; 299:405-408.
44. Dominguez F, Yanez-Mo M, Sanchez-Madrid F, Simon C. Embryonic implantation and leukocyte transendothelial migration: different processes with similar players? Faseb J 2005; 19:1056-1060.
45. Bulla R, Villa A, Bossi F, et al. VE-cadherin is a critical molecule for trophoblast-endothelial cell interaction in decidual spiral arteries. Exp Cell Res 2005; 303:101-113.
46. Aplin JD. Embryo implantation: the molecular mechanism remains elusive. Reprod Biomed Online 2006; 13:833-839. This excellent review outlines the importance of adhesion molecules for successful embryo implantation.
47. Red-Horse K, Kapidzic M, Zhou Y, et al. EPHB4 regulates chemokine-evoked trophoblast responses: a mechanism for incorporating the human placenta into the maternal circulation. Development 2005; 132:4097-4106.
48. Hirota Y, Osuga Y, Koga K, et al. The expression and possible roles of chemokine CXCL11 and its receptor CXCR3 in the human endometrium. J Immunol 2006; 177:8813-8821. This study demonstrates the expression and potential roles for a chemokine ligand system in the human endometrium.
49. Kitaya K, Nakayama T, Daikoku N, et al. Spatial and temporal expression of ligands for CXCR3 and CXCR4 in human endometrium. J Clin Endocrinol Metab 2004; 89:2470-2476.
50. Hess AP, Hamilton AE, Talbi S, et al. Decidual stromal cell response to paracrine signals from the trophoblast: amplification of immune and angiogenic modulators. Biol Reprod 2007; 76:102-117. This important study reveals candidates in the important crosstalk between foetal and maternal cells.