Extracellular matrix proteases - Cytokine regulation role in cancer and pregnancy

Frontiers in Bioscience

Volumn 14, Issue 4, 2009, Pages 1571-1588

  Sheu, Bor Ching ^a   Chang, Wen Chun ^a   Cheng, Chieh Yang ^a   Wang, Peng Hui ^b   Lin, Shiming ^c   Huang, Su Cheng ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Cancer; Cytokine; Extracellular matrix; Matrix metalloproteinases; Pregnancy; Review; Tissue inhibitors of metalloproteinases

Indexed keywords

CYTOKINE; MATRIX METALLOPROTEINASE;

ENZYMOLOGY; EXTRACELLULAR MATRIX; FEMALE; HUMAN; METABOLISM; NEOPLASM; PATHOPHYSIOLOGY; PHYSIOLOGY; PREGNANCY; REVIEW;

CYTOKINES; EXTRACELLULAR MATRIX; FEMALE; HUMANS; MATRIX METALLOPROTEINASES; NEOPLASMS; PREGNANCY;

EID: 63849315925     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/3325     Document Type: Article

References (112)

1. Visse R & H. Nagase: Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ Res 92, 827-839 (2003). (Pubitemid 36542523)
2. Nelson A.R, B. Fingleton, M.L. Rothenberg & L.M. Matrisian: Matrix metalloproteinases: biologic activity and clinical implications. J Clin Oncol 18, 1135-1149 (2000). (Pubitemid 30123793)
3. Sheu B.C, S.M. Hsu, H.N. No, H.C. Lien, S.C. Huang & R.H. Lin: A Novel Role of Metalloproteinase in Cancer-mediated Immunosuppression. Cancer Res 61, 237-242 (2001).
4. Sheu B.C, H.C. Lien, H.N. Ho, H.H. Lin, S.N. Chow, S.C. Huang & S.M. Hsu: Increased Expression and Activation of Gelatinolytic Matrix Metalloproteinases Is Associated with the Progression and Recurrence of Human Cervical Cancer. Cancer Res 63, 6537-6542 (2003).
5. Yan C & D.D. Boyd: Regulation of Matrix Metalloproteinase Gene Expression. J Cell Physiol 211, 19-26 (2007). (Pubitemid 46363892)
6. Joseph D.R & A.K. Raouf: Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease. Biochem Pharmacol 75, 346-359 (2008).
7. Holmbeck K, P. Bianco & H. Birkedal-Hansen: MT1-MMP: A collagenase essential for tumor cell invasive growth. Cancer Cell 4, 83-84 (2003). (Pubitemid 37040822)
8. Ueda J, M. Kajita, N. Suenaga, K. Fujii & M. Seiki: Sequence-specific silencing of MT1-MMP expression suppresses tumor cell migration and invasion: Importance of MT1-MMP as a therapeutic target for invasive tumors. Oncogene 22, 8716-8722 (2003). (Pubitemid 38010495)
9. Iida J, K.L. Wilhelmson, W.A. Price, C.M. Wilson, D. Pei, L.T. Furcht & J.B. McCarthy: Membrane type-1 matrix metalloproteinase promotes human melanoma invasion and growth. J Invest Dermatol 122, 167-176 (2004). (Pubitemid 38120271)
10. Bendardaf R, H. Lamlum, P. Vihinen, R. Ristamaki, J. Laine & S. Pyrhonen: Low collagenase-1 (MMP-1) and MT1-MMP expression levels are favorable survival markers in advanced colorectal carcinoma. Oncol 65, 337-346 (2003). (Pubitemid 38064946)
11. Kayano K, T. Shimada, T. Shinomiya, S. Nakai, Y. Hisa, T. Aoki, M. Seiki & Y. Okada: Activation of pro-MMP-2 mediated by MT1-MMP in human salivary gland carcinomas: Possible regulation of pro-MMP-2 activation by TIMP-2. J Pathol 202, 403-411 (2004). (Pubitemid 38456158)
12. Zhao Y.G, A.Z. Xiao, R.G. Newcomer, H.I. Park, T. Kang, L.W. Chung, M.G. Swanson, H.E. Zhau, J. Kurhanewicz & Q.X. Sang: Activation of pro-gelatinse B by endometase/matrilysin-2 promotes invasion of human prostate cancer cells. J Biol Chem 278, 15056-15064 (2003). (Pubitemid 36799839)
13. Ramos M.C, H. Steinbrenner, D. Stuhlmann, H. Sies & P. Brenneisen: Induction of MMP-10 and MMP-1 in a squamous cell carcinoma cell line by ultraviolet radiation. J Biol Chem 385, 75-86 (2004). (Pubitemid 38240297)
14. Nakopoulou L, E.G. Panayotopoulou, I. Giannopoulou, P. Alexandrou, S. Katsarou, P. Athanassiadou & A. Keramopoulos: Stromelysin-3 protein expression in invasive breast cancer: Relation to proliferation, cell survival and patients' outcome. Modern Pathol 15, 1154-1161 (2002). (Pubitemid 35435133)
15. Ahokas K, M.L. Karjalainen-Lindsberg, E. Sihvo, K. Isaka, J. Salo & U. Saarialho-Kere: Matrix metalloproteinases 21 and 26 are differentially expressed in esophageal squamous cell cancer. Tumour Biol 27, 133-141 (2006).
16. Li Y.J, Z.M. Wei, Y.X. Meng & X.R. Ji: Beta-catenin upregulates the expression of cyclin-D1, c-myc and MMP-7 in human pancreatic cancer: relationships withcarcinogenesis and metastasis. World J Gastroenterol 11, 2117-2123 (2005).
17. Kerkela E & U. Saarialho-Kere: Matrix metalloproteinases in tumor progression: focus on basal and squamous cell skin cancer. Exp Dermatol 12, 109-125 (2003). (Pubitemid 36934696)
18. Sonata J, B. Laurence, M.Y. Janet & A.D. Yves: Modifying the soil to affect the seed: role of stromalderived matrix metalloproteinases in cancer progression. Cancer Metastasis Rev 25, 35-43 (2006).
19. Yasutake U, S. Tetsuji & H. Kosei: Action of Antiproteases on Pancreatic Cancer Cells. J Pancreas 8, 479-487 (2007).
20. Nemeth J.A, R. Yousif, M. Herzog, M. Che, J. Upadhyay, B. Shekarriz, S. Bhagat, C. Mullins, R. Fridman & M.L. Cher: Matrix metalloproteinase activity, bone matrix turnover, and tumor cell proliferation in prostate cancer bone metastasis. J Natl Cancer Inst 94, 17-25 (2002). (Pubitemid 34082839)
21. Brauer P.R: MMPs - Role in Cardiovascular Development and Disease. Front Biosci 11, 447-478 (2006). (Pubitemid 43258156)
22. Grutzmann R, J. Luttges, B. Sipos, O. Ammerpohl, F. Dobrowolski, I. Alldinger, S. Kersting, D. Ockert, R. Koch, H. Kalthoff, H.K. Schackert, H.D. Saeger, G. Kloppel & C. Pilarsky: ADAM9 expression in pancreatic cancer is associated with tumour type and is a prognostic factor in ductal adenocarcinoma. Br J Cancer 90, 1053-1058 (2004). (Pubitemid 38495828)
23. Le Pabic H, D. Bonnier, U.M. Wewer, A. Coutand, O. Musso, G. Baffet, B. Clement & N. Theret: ADAM12 in human liver cancers: TGF-beta-regulated expression in stellate cells is associated with matrix remodeling. Hepatology 37, 1056-1066 (2003). (Pubitemid 36538682)
24. Roy R, U.M. Wewer, D. Zurakowski, S.E. Pories & M.A. Moses: ADAM12 cleaves extracellular matrix proteins and correlates with cancer status and stage. J Biol Chem 279, 51323-51330 (2004). (Pubitemid 40017878)
25. Kodama T, E. Ikeda, A. Okada, T. Ohtsuka, M. Shimoda, T. Shiomi, K. Yoshida, M. Nakada, E. Ohuchi & Y. Okada: ADAM12 is selectively overexpressed in human glioblastomas and is associated with glioblastoma cell proliferation and shedding of heparin-binding epidermal growth factor. Am J Pathol 165, 1743-1753 (2004). (Pubitemid 39435171)
26. Kashiwagi M, M. Tortorella, H. Nagase & K. Brew: TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAMTS4) and aggrecanase 2 (ADAM-TS5). J Biol Chem 276, 12501-12504 (2001).
27. Porter J.F, S. Shen & D.T. Denhardt: Tissue inhibitor of metalloproteinase-1 stimulates proliferation of human cancer cells by inhibiting a metalloproteinase. Br J Cancer 90, 463-470 (2004). (Pubitemid 38250646)
28. Bloomston M, A. Shafii, E.E. Zervos & A.S. Rosemurgy: TIMP-1 overexpression in pancreatic cancer attenuates tumor growth, decreases implantation and metastasis, and inhibits angiogenesis. J Surg Res 102, 39-44 (2002).
29. Schrohl A.S, M.N. Holten-Andersen, H.A. Peters, M.. Look, M.N. Holten-Andersen, U. Hansen, N. Brunner, H.J. Nielsen, M. Illemann & B.S. Nielsen: Localization of tissue inhibitor of metalloproteinases 1 (TIMP-1) in human colorectal adenoma and adenocarcinoma. Int J Cancer 113, 198-206 (2005). (Pubitemid 39628309)
30. Meijer-van Gelder M.E, J.G. Klijn, N. Brunner & J.A. Foekens: Tumor tissue levels of tissue inhibitor of metalloproteinase-1 as a prognostic marker in primary breast cancer. Clin Cancer Res 10, 2289-2298 (2004). (Pubitemid 38445686)
31. Feldman A.L, W.G. Stetler-Stevenson, N.G. Costouros, V. Knezevic, G. Baibakov, H.R.J. Alexander, D. Lorang, S.M. Hewitt, D.W. Seo, M.S. Miller, S. O'Connor & S.K. Libutti: Modulation of tumor-host interactions, angiogenesis, and tumor growth by tissue inhibitor of metalloproteinase 2 via a novel mechanism. Cancer Res 64, 4481-4486 (2004). (Pubitemid 38856919)
32. Zhao Y.G, A.Z. Xiao, H.I. Park, R.G. Newcomer, M. Yan, Y.G. Man, S.C. Heffelfinger & Q.X. Sang: Endometase/matrilysin-2 in human breast ductal carcinoma in situ and its inhibition by tissue inhibitors of metalloproteinases-2 and-4: A putative role in the initiation of breast cancer invasion. Cancer Res 64, 590-598 (2004). (Pubitemid 38120898)
33. Ahonen M, M. Poukkula, A.H. Baker, M. Kashiwagi, H. Nagase, J.E. Eriksson & V.M. Kahari: Tissue inhibitor of metalloproteinases-3 induces apoptosis in melanoma cells by stabilization of death receptors. Oncogene 22, 2121-2134 (2003). (Pubitemid 36539562)
34. Ripley D, R. Tunuguntla, L. Susi & N. Chegini: Expression of matrix metalloproteinase-26 and tissue inhibitors of metalloproteinase-3 and -4 in normal ovary and ovarian carcinoma. Int J Gynecol Cancer 16, 1794-1800 (2006). (Pubitemid 44470038)
35. Lizarraga F, M. Espinosa, V. Maldonado & J. Melendez-Zajgla: Tissue inhibitor of metalloproteinases-4 is expressed in cervical cancer patients. Anticancer Res 25, 623-627 (2005). (Pubitemid 40470073)
36. Shin'ichi M, N. Michio, Y. Keiichi, I. Genichiro, H. Takahiro, E. Yasushi, S. Takafumi, M. Hiroyuki, S. Zhang, C. Tsutomu & O. Atsushi: Matrix metalloproteinase-7 triggers the matricrine action of insulin-like growth factor-II via proteinase activity on insulin-like growth factor binding protein 2 in the extracellular matrix. Cancer Sci 98, 685-691 (2007).
37. Remacle-Bonnet M.M, F.L. Garrouste & G.J. Pommier: Surface-bound plasmin induces selective proteolysis of insulin-like-growth-factor (IGF)-binding protein-4 (IGFBP-4) and promotes autocrine IGF-II bioavailability in human colon-carcinoma cells. Int J Cancer 72, 835-843 (1997). (Pubitemid 27431528)
38. Manes S, M. Llorente, R.A. Lacalle, C. Gómez-Moutón, L. Kremer, E. Mira & A.C. Martínez: The matrix metalloproteinase-9 regulates the insulin-like growth factor-triggered autocrine response in DU-145 carcinoma cells. J Biol Chem 274, 6935-6945 (1999).
39. Ii M, H. Yamamoto, Y. Adachi, Y. Maruyama & Y. Shinomura: Role of Matrix Metalloproteinase-7 (Matrilysin) in Human Cancer Invasion, Apoptosis, Growth, and Angiogenesis. Exp Biol Med 231, 20-27 (2006). (Pubitemid 43063974)
40. David C.D, J.R. Paul, O. Angela, R.W. Derrick & J.B. Robert: Tumor-derived death receptor 6 modulates dendritic cell development. Cancer Immunol Immunother Epub ahead of print (2007).
41. Frey A.B, A. Wali, H. Pass & F. Lonardo: Osteopontin is linked to p65 and MMP-9 expression in pulmonary adenocarcinoma but not in malignant pleural Mesothelioma. Histopathology 50, 720-726 (2007). (Pubitemid 46683928)
42. Philip Y.W, M. Zhiyong, G. Hongtao, S.Y. Shiva, G. Chengjiang, W. Junping, E.M. Carlos, C. Bryan & C.K. Paul: Osteopontin silencing by small interfering RNA suppresses in vitro and in vivo CT26 murine colon adenocarcinoma metastasis. Carcinogenesis 26, 741-751 (2005).
43. Agnihotri R, H.C. Crawford, H. Haro, L.M. Matrisian, M.C. Havrda & L. Liaw: Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin). J Biol Chem 276, 28261-28267 (2001).
44. Takafuji V, M. Forgues, E. Unsworth, P. Goldsmith & X.W. Wang: An osteopontin fragment is essential for tumor cell invasion in hepatocellular carcinoma. Oncogene 26, 6361-6371 (2007). (Pubitemid 47494216)
45. Massimiliano D.B, C.C. Robert, G.S. Darlene, J.S. Jianhe, M.S. Jack, V.R. Heidi, M. H. John, M. Tsz-Kwong & Y.H.K. John: Patched haploinsufficient mouse rhabdomyosarcoma. Eur J Cancer 43, 1308-1317 (2007).
46. Safina A, E. Vandette & A.V. Bakin: ALK5 promotes tumor angiogenesis by upregulating matrix metalloproteinase-9 in tumor cells. Oncogene 26, 2407-2422 (2007). (Pubitemid 46597273)
47. Robinson S.C, K.A. Scott & F.R. Balkwill: Chemokine stimulation of monocyte matrix metalloproteinase-9 requires endogenous TNFalpha. Eur J Immunol 32, 404-412 (2002). (Pubitemid 34173332)
48. Sun Y.X, J. Wang, C.E. Shelburne, D.E. Lopatin, A.M. Chinnaiyan, M.A. Rubin, K.J. Pienta & R.S. Taichman: Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo. J Cell Biochem 89, 462-473 (2003). (Pubitemid 36648768)
49. Zhong J, M.M. Gencay, L. Bubendorf, J.K. Burgess, H. Parson, B.W. Robinson, M. Tamm, J.L. Black & M. Roth: ERK1/2 and p38 MAP Kinase Control MMP-2, MT1-MMP, and TIMP Action and Affect Cell Migration: A Comparison Between Mesothelioma and Mesothelial Cells. J Cell Physiol 207, 540-552 (2006).
50. Ewa L & M. Marcin: The biological role of HGF-MET axis in tumor growth and development of metastasis. Front Biosci 13, 1271-1280 (2008).
51. Zhou H.Y, Y.L. Pon & A.S. Wong: Synergistic Effects of Epidermal Growth Factor and Hepatocyte Growth Factor on Human Ovarian Cancer Cell Invasion and Migration: Role of Extracellular Signal-Regulated Kinase 1/2 and p38 Mitogen-Activated Protein Kinase. Endocrinology 148, 5195-5208 (2007). (Pubitemid 350012618)
52. Sherman M.C, X. Bing, C.B.L. James, K.W.C. Benny & S.Y.L. Allan: Interferon-γ regulation of TNFα-induced matrix metalloproteinase 3 expression and migration of human glioma T98G cells. Int J Cancer 121, 1190-1196 (2007).
53. Ville B, S. Tiina, V. Susanna, K. Tuula, P. Pauli & U. Saarialho-Kere: Increased expression of matrix metalloproteinases-21 and -26 and TIMP-4 in pancreatic adenocarcinoma. Mod Pathol 20, 1128-1140 (2007). (Pubitemid 47609068)
54. Kitamura T & M.M. Taketo: Keeping Out the Bad Guys: Gateway to Cellular Target Therapy. Cancer Res 67, 10099-10102 (2007). (Pubitemid 350070778)
55. Marisa P.C, M.O. Isabel, M.R. Saloḿon, G.B. David, C.V. Xonia, V. Inmaculada, P. Atanasio, G.A. Alicia & T. Joaquin: Role of metalloproteinases MMP-9 and MT1-MMP in CXCL12-promoted myeloma cell invasion across basement membranes. J Pathol 208, 108-118 (2006).
56. Chu C.Y, S.T. Cha, C.C. Chang, C.H. Hsiao, C.T. Tan, Y.C. Lu, S.H. Jee & M.L. Kuo: Involvement of matrix metalloproteinase-13 in stromal-cell-derived factor 1α-directed invasion of human basal cell carcinoma cells. Oncogene 26, 2491-2501 (2007).
57. Lin E.Y, A.V. Nguyen, R.G. Russell & J.W. Pollard: Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med 193, 727-740 (2001).
58. Red-Horse K, Y. Zhou, O. Genbacev, A. Prakobphol, R. Foulk, M. McMaster & S.J. Fisher: Trophoblast differentiation during embryo implantation and formation of the maternal-fetal interface. J Clin Invest 114, 744-754 (2004). (Pubitemid 39578730)
59. Huang H.Y, Y. Wen, J.C. Irwin, J.S. Kruessel, Y.K. Soong & M.L. Polan: Cytokine mediated regulation of 92-kilodalton type IV collagenase, tissue inhibitor of metalloproteinase-1 (TIMP-1), and TIMP-3 messenger ribonucleic acid expression in human endometrial stromal cells. J Clin Endocrinol Metab 83, 1721-1729 (1998). (Pubitemid 28501048)
60. Staun-Ram E & E. Shalev: Human trophoblast function during the implantation process. Reprod Biol Endocrinol 3, 56 (2005).
61. Hrabec E, J. Naduk, M. Strek & Z. Hrabec: Type IV collagenases (MMP-2 and MMP-9) and their substrates-intracellular proteins, hormones, cytokines, chemokines and their receptors. Postepy Biochem 53, 37-45 (2007).
62. Behrendtsen O, C.M. Alexander & Z. Werb: Metalloproteinases mediate extracellular matrix degradation by cells from mouse blastocyst outgrowths. Development 114, 447-456 (1992).
63. Isaka K, S. Usuda, H. Ito, Y. Sagawa, H. Nakamura, H. Nishi, Y. Suzuki, Y.F. Li & M. Takayama: Expression and activity of matrix metalloproteinase 2 and 9 in human trophoblasts. Placenta 24, 53-64 (2003). (Pubitemid 37184696)
64. Vigano P, S. Mangioni, F. Pompei & I. Chiodo: Maternal-conceptus Cross talk -A review. Placenta 24, 56-61 (2003).
65. Meisser A, P. Cameo, D. Islami, A. Campana & P. Bischof: Effects of interleukin-6 (IL-6) on cytotrophoblastic cells. Mol Hum Reprod 5, 1055-1058 (1999). (Pubitemid 29518910)
66. Roth I & S.J. Fisher: IL-10 is an autocrine inhibitor of human placental cytotrophoblast MMP-9 production and invasion. Dev Biol 205, 194-204 (1999). (Pubitemid 29042668)
67. Mei-rong Z, Q. Wei, L. Yu-xia, Z. Zhi-bin, L. Dong & W. Yan-ling: Dual effect of transforming growth factor β1 on cell adhesion and invasion in human placenta trophoblast cells. Reproduction 132, 333-341 (2006).
68. Karmakar S & C. Das: Regulation of trophoblast invasion by IL-1beta and TGF-beta1. Am J Reprod Immunol 48, 210-219 (2002).
69. Qiu Q, M. Yang, B.K. Tsang & A. Gruslin: EGF-induced trophoblast secretion of MMP-9 and TIMP-1 involves activation of both PI3K and MAPK signaling pathways. Reproduction 128, 355-363 (2004). (Pubitemid 39242711)
70. Anteby E.Y, C. Greenfield, S. Natanson-Yaron, D. Goldman-Wohl, Y. Hamani, V. Khudyak, I. Ariel & S. Yagel: Vascular endothelial growth factor, epidermal growth factor and fibroblast growth factor-4 and -10 stimulate trophoblast plasminogen activator system and metalloproteinase-9. Mol Hum Reprod 10, 229-235 (2004). (Pubitemid 38456027)
71. Simón C, J.C. Martin & A. Pellicer: Paracerine regulators of implantation. Baillieres Clin Obstet Gynaecol 14, 815-826 (2000).
72. Hamilton G.S, J.J. Lysiak, V.K. Han & P.K. Lala: Autocrine-paracrine regulation of human trophoblast invasiveness by insulin-like growth factor (IGF)-II and IGF-binding protein (IGFBP)-1. Exp Cell Res 244, 147-156 (1998). (Pubitemid 28480863)
73. Marie C, M. Arielle, H. Luise & B. Paul: Involvement of MAPK pathway in TNF-α-induced MMP-9 expression in human trophoblastic cells. Mol Hum Reprod 12, 225-232 (2006).
74. Monzón-Bordonaba F, F. Vadillo-Ortega & R.F. Feinberg: Modulation of trophoblast function by tumor necrosis factor-alpha: a role in pregnancy establishment and maintenance? Am J Obstet Gynecol 187, 1574-1580 (2002). (Pubitemid 36026690)
75. Bauer S, J. Pollheimer, J. Hartmann, P. Husslein, J.D. Aplin & M. Knofler: Tumor necrosis factor-alpha inhibits activator inhibitor-1 in first-trimester villous explant cultures. Clin Endocrinol Metab 89, 812-822 (2004).
76. Malmström E, M. Sennström, A. Holmberg, H. Frielingsdorf, E. Eklund, L. Malmström, E. Tufvesson, M.F. Gomez, G. Westergren-Thorsson, G. Ekman-Ordeberg & A. Malmström: The importance of fibroblasts in remodelling of the human uterine cervix during pregnancy and parturition. Mol Hum Reprod 13, 333-341 (2007). (Pubitemid 47061644)
77. Suk J.C, Y.O. Soo, H.K. Jong & R.R. Cheong: Changes of nuclear factor kappa B (NF-κB), cyclooxygenase-2 (COX-2) and matrix metalloproteinase-9 (MMP-9) in human myometrium before and during term labor. Eur J Obstet Gynecol Reprod Biol 132, 182-188 (2007).
78. Romero R, T. Chaiworapongsa, J. Espinoza, R. Gomez, B.H. Yoon, S. Edwin, M. Mazor, E. Maymon & S. Berry: Fetal plasma MMP-9 concentrations are elevated in preterm premature rupture of the membranes. Am J Obstet Gynecol 187, 1125-1130 (2002). (Pubitemid 35397444)
79. Inagaki N, C. Stern, J. McBain, A. Lopata, L. Kornman & D. Wilkinson: Analysis of intra-uterine cytokine concentration and matrix-metalloproteinase activity in women with recurrent failed embryo transfer. Hum Reprod 18, 608-615 (2003). (Pubitemid 36329334)
80. Schuster N & K. Krieglstein: Mechanisms of TGF-β-mediated apoptosis. Cell Tissue Res 307, 1-14 (2002).
81. Yu Y.S, Q.D. Lin & A.M. Zhao: Relationship between expression of TGF-β mRNA in mice decidua and spontaneous abortion. Prog Obstet Gynecol 11, 113-115 (2002).
82. Choong P.F & A.P. Nadesapillai: Urokinase plasminogen activator system: A multifunction role in tumor progression and metastasis. Clin Orthop Relat Res 415, 46-58 (2003).
83. Wender-Ozegowska E, G. Michalowska-Wender, A. Zawiejska, M. Pietryga, J. Brazert & M. Wender: Concentration of chemokines in peripheral blood in first trimester of diabetic pregnancy. Acta Obstetricia et Gynecologica 87, 14-19 (2008).
84. Hiden U, E. Glitzner, M. Ivanisevic, J. Djelmis, C. Wadsack, U. Lang & G. Desoye: MT1-MMP expression in first-trimester placental tissue is upregulated in type 1 diabetes as a result of elevated insulin and tumor necrosis factor-alpha levels. Diabetes 57, 150-157 (2008).
85. Slattery M.M & J.J. Morrison: Preterm delivery. Lancet 360, 1489-1497 (2002). (Pubitemid 35356329)
86. Goldman S, A. Weiss, Y. Eyall & E. Shaker: Differential activity of the gelatinase (matrix metalloproteinases 2 and 9) in the fetal membranes and deciduas, associated with labour. Mol Hum Reprod 9, 367-373 (2003). (Pubitemid 36748842)
87. Saji F, Y. Samejima, S. Kamiura, K. Sawai, K. Shimoya & T. Kimura: Cytokine production in chorioamnionitis. J Reprod Immunol 47, 185-196 (2000). (Pubitemid 30621435)
88. Sadowsky D.W, K.M. Adams, M.G. Gravett, S.S. Witkin & M.J. Novy: Preterm labor is induced by intraamniotic infusions of interleukin-1beta and tumor necrosis factor-alpha but not by interleukin-6 or interleukin-8 in a nonhuman primate model. Am J Obstet Gynecol 195, 1578-1589 (2006). (Pubitemid 44792645)
89. Oner C, F. Schatz, G. Kizilay, W. Murk, L.F. Buchwalder, U.A. Kayisli, A. Arici & C.J. Lockwood: Progestin-inflammatory cytokine interactions affect matrix metalloproteinase-1 and -3 expression in term decidual cells: implications for treatment of chorioamnionitis-induced preterm delivery. J Clin Endocrinol Metab 93, 252-259 (2008).
90. Reister F, J.C. Kingdom, P. Ruck, K. Marzusch, W. Heyl, U. Pauer, P. Kaufmann, W. Rath & B. Huppertz: Altered protease expression by periarterial trophoblast cells in severe early-onset preeclampsia with IUGR. J Perinat 34, 272-279 (2006). (Pubitemid 44114562)
91. Zhao F.X, Y.Y. Zhang, R.H. Liu & S.M. Li: Effect of blockage of costimulatory signal on murine abortion-prone model. Chin Med J 120, 1247-1250 (2007).
92. Di Simone N, F. Di Nicuolo, M. Sanguinetti, S. Ferrazzani, M.C. D'Alessio, R. Castellani, A. Bompiani & A. Caruso: Low-molecular Weight Heparin Induces In vitro Trophoblast Invasiveness: Role of Matrix Metalloproteinases and Tissue Inhibitors. Placenta 28, 298-304 (2007). (Pubitemid 46505937)
93. Fortson W, K.D. Beharry, S. Nageotte, J.H. Sills, Y. Stavitsky, T. Asrat & H.D. Modanlou: Vaginal versus oral indomethacin in a rabbit model for non-infection-mediated preterm birth: an alternate tocolytic approach. Am J Obstet Gynecol 195, 1058-1064 (2006). (Pubitemid 44415664)
94. Vadim I, R. Waheed, K. Tatiana, N. Aleksandra & R. Matthias: Natural nutrient mixture effectively reduces collagen matrix contraction driven by human uterine smooth muscle cells. J Obstet Gynaecol Res 32, 23-31 (2006).
95. Karen L.K, V.A. Cande, P. Jessica & E.R. Sandra: The effect of a matrix metalloproteinase inhibitor on inflammation-mediated preterm delivery. Am J Obstet Gynecol 196, 551-553 (2007).
96. Kaylon L.B, Z. Zhiming, E. Esther, C.W. Richard & G.O. Kevin: Down-Regulation of Endometrial Matrix Metalloproteinase-3 and -7 Expression in vitro and Therapeutic Regression of Experimental Endometriosis in vivo by a Novel Nonsteroidal Progesterone Receptor Agonist, Tanaproget. J Clin Endocrinol Metab 91, 1554-1560 (2006).
97. Ramnath N & P.J. Creaven: Matrix metalloproteinase inhibitors. Curr Oncol Rep 6, 96-102 (2004). (Pubitemid 38898836)
98. Overall C.M & O. Kleifeld: Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy. Nat Rev Cancer 6, 227-239 (2006). (Pubitemid 43292566)
99. Zacchigna S, L. Zentilin, M. Morini, R. Dell'Eva, D.M. Noonan, A. Albini & M.Giacca: AAV-mediated gene transfer of tissue inhibitor of metalloproteinases-1 inhibits vascular tumor growth and angiogenesis in vivo. Cancer Gene Ther 11, 73-80 (2004). (Pubitemid 38057817)
100. Megias J, J. Busserolles & M.J. Alcaraz: The carbon monoxide-releasing molecule CORM-2 inhibits the inflammatory response induced by cytokines in Caco-2 cells. Br J Pharmacol 150, 977-986 (2007). (Pubitemid 46625094)
101. Kwang S.A, G. Xing, S. Gautam, M.C. Madan, K.J. Anil & B.A. Bharat: Deficiency of NRH: Quinone Oxidoreductase 2 Differentially Regulates TNF Signaling in Keratinocytes: Up-regulation of Apoptosis Correlates with Down-regulation of Cell Survival Kinases. Cancer Res 67, 10004-10011 (2007). (Pubitemid 47621251)
102. Manoj K.P, K.S. Santosh, S. Bokyung, S. Gautam, B.K. Ajaikumar & B.A. Bharat: Butein, a Tetrahydroxychalcone, Inhibits Nuclear Factor (NF)-κB and NF-κB-regulated Gene Expression through Direct Inhibition of IκBα Kinase β on Cysteine 179 Residue. J Biol Chem 282, 17340-17350 (2007).
103. Gautam S, S.A. Kwang, K.P. Manoj & B.A. Bharat: Celastrol, a novel triterpene, potentiates TNF-induced apoptosis and suppresses invasion of tumor cells by inhibiting NF-κB-regulated gene products and TAK1-mediated NF-κB activation. Blood 109, 2727-2735 (2007). (Pubitemid 46482064)
104. Manoj K.P, S. Bokyung, S.A. Kwang, B.K. Ajaikumar, M.C. Madan & B.A. Bharat: Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-κB signaling pathway. Blood 110, 3517-3525 (2007). (Pubitemid 350159615)
105. Kwang S.A, S. Gautam, C. Ta-Hsiang, T.C.N. Saskia, M.C. Madan, A.P. Michael, Y. Anas & B.A. Bharat: SalinosporamideA (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-κB-regulated gene products. Blood 110, 2286-2295 (2007). (Pubitemid 47523146)
106. Shih-Wei W, P. Shiow-Lin, P. Chieh-Yu, H. Der-Yi, T. An-Chi, C. Ya-Ling, G. Jih-Hwa, K. Sheng-Chu, L. Kuo-Hsiung & T. Che-Ming: CHM-1 inhibits hepatocyte growth factor-induced invasion of SK-Hep-1 human hepatocellular carcinoma cells by suppressing matrix metalloproteinase-9 expression. Cancer Lett 257, 87-96 (2007).
107. Du H.Y, M. Olivo, R. Mahendran, Q. Huang, H.M. Shen, C.N. Ong & B.H. Bay: Hypericin photoactivation triggers down-regulation of matrix metalloproteinase-9 expression in well-differentiated human nasopharyngeal cancer cells. Cell Mol Life Sci 64, 979-988 (2007). (Pubitemid 46597767)
108. Xiyun D, H. Guangchun, L. Andrea, C. Ya & M. Chad: Adenovirus-mediated expression of TIMP-1 and TIMP-2 in bone inhibits osteolytic degradation by human prostate cancer. Int J Cancer 122, 209-218 (2008).
109. Dias N & C.A. Stein: Antisense oligonucleotides: Basic concepts and mechanisms. Mol Cancer Ther 1, 347-355 (2002).
110. Yonemura Y, Y. Endo, H. Fujita, K. Kimura, K. Sugiyama, N. Momiyama, H. Shimada & T. Sasaki: Inhibition of peritoneal dissemination in human gastric cancer by MMP-7-specific antisense oligonucleotide. J Exp Clin Cancer Res 20, 205-212 (2001). (Pubitemid 32641062)
111. Tan S, D. Guschin, A. Davalos, Y.L. Lee, A.W. Snowden, Y. Jouvenot, H.S. Zhang, K. Howes, A.R. McNamara, A. Lai, C. Ullman, L. Reynolds, M. Moore, M. Isalan, L.P. Berg, B. Campos, Q. Hong, S.K. Spratt, C.C. Case, C.O. Pabo, J. Campisi & P.D. Gregory: Zinc-finger protein-targeted gene regulation: Genomewide single-gene specificity. Proc Natl Acad Sci 100, 11997-12002 (2003). (Pubitemid 37271504)
112. Visser A.E, P.J. Verschure, W.M. Gommans, H.J. Haisma & M.G. Rots: Step into the groove: Engineered transcription factors as modulators of gene expression. Adv Genet 56, 131-161 (2006). (Pubitemid 43776134)