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Volumn 108, Issue 1, 2013, Pages 155-161

Homologous recombination mediates cellular resistance and fraction size sensitivity to radiation therapy

Author keywords

Cell cycle; DNA double strand break repair; Fraction size sensitivity; Fractionated radiotherapy; Homologous recombination

Indexed keywords

ARTICLE; CELL CYCLE; CELL FRACTIONATION; CELL SURVIVAL; CHO CELL; CLONOGENESIS; CONTROLLED STUDY; DNA END JOINING REPAIR; DNA REPAIR; DOUBLE STRANDED DNA BREAK; EXCISION REPAIR; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; HOMOLOGOUS RECOMBINATION; KINETICS; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; RADIOSENSITIVITY; WILD TYPE;

EID: 84883148051     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2013.05.012     Document Type: Article
Times cited : (28)

References (46)
  • 1
    • 0030474646 scopus 로고    scopus 로고
    • Prognostic factors for acute and late skin reactions in radiotherapy patients
    • I. Turesson, J. Nyman, E. Holmberg, and A. Oden Prognostic factors for acute and late skin reactions in radiotherapy patients Int J Radiat Oncol Biol Phys 36 1996 1065 1075
    • (1996) Int J Radiat Oncol Biol Phys , vol.36 , pp. 1065-1075
    • Turesson, I.1    Nyman, J.2    Holmberg, E.3    Oden, A.4
  • 3
    • 0001086274 scopus 로고
    • The four R's of radiotherapy
    • H.R. Withers The four R's of radiotherapy Adv Radiat Res 15 1975 241 247
    • (1975) Adv Radiat Res , vol.15 , pp. 241-247
    • Withers, H.R.1
  • 6
    • 0033059072 scopus 로고    scopus 로고
    • Fractionation sensitivities and dose-control relations of head and neck carcinomas: Analysis of the randomized hyperfractionation trials
    • M. Stuschke, and H.D. Thames Fractionation sensitivities and dose-control relations of head and neck carcinomas: analysis of the randomized hyperfractionation trials Radiother Oncol 51 1999 113 121
    • (1999) Radiother Oncol , vol.51 , pp. 113-121
    • Stuschke, M.1    Thames, H.D.2
  • 7
    • 33646862836 scopus 로고    scopus 로고
    • Effect of radiotherapy fraction size on tumour control in patients with early-stage breast cancer after local tumour excision: Long-term results of a randomised trial
    • J.R. Owen, A. Ashton, and J.M. Bliss Effect of radiotherapy fraction size on tumour control in patients with early-stage breast cancer after local tumour excision: long-term results of a randomised trial Lancet Oncol 7 2006 467 471
    • (2006) Lancet Oncol , vol.7 , pp. 467-471
    • Owen, J.R.1    Ashton, A.2    Bliss, J.M.3
  • 8
    • 40949094327 scopus 로고    scopus 로고
    • The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: A randomised trial
    • S.M. Bentzen, R.K. Agrawal, and E.G. Aird The UK Standardisation of Breast Radiotherapy (START) Trial A of radiotherapy hypofractionation for treatment of early breast cancer: a randomised trial Lancet Oncol 9 2008 331 341
    • (2008) Lancet Oncol , vol.9 , pp. 331-341
    • Bentzen, S.M.1    Agrawal, R.K.2    Aird, E.G.3
  • 9
    • 76649099557 scopus 로고    scopus 로고
    • Long-term results of hypofractionated radiation therapy for breast cancer
    • T.J. Whelan, J.P. Pignol, and M.N. Levine Long-term results of hypofractionated radiation therapy for breast cancer N Engl J Med 362 2010 513 520
    • (2010) N Engl J Med , vol.362 , pp. 513-520
    • Whelan, T.J.1    Pignol, J.P.2    Levine, M.N.3
  • 10
    • 77958183224 scopus 로고    scopus 로고
    • Hypofractionated adjuvant whole breast radiotherapy: Progress and prospects
    • J. Yarnold, and J. Haviland Hypofractionated adjuvant whole breast radiotherapy: progress and prospects Acta Oncol 49 2010 1288 1292
    • (2010) Acta Oncol , vol.49 , pp. 1288-1292
    • Yarnold, J.1    Haviland, J.2
  • 11
    • 77953355142 scopus 로고    scopus 로고
    • Hypofractionation should be the new 'standard' for radiation therapy after breast conserving surgery
    • C.L. Holloway, V. Panet-Raymond, and I. Olivotto Hypofractionation should be the new 'standard' for radiation therapy after breast conserving surgery Breast 19 2010 163 167
    • (2010) Breast , vol.19 , pp. 163-167
    • Holloway, C.L.1    Panet-Raymond, V.2    Olivotto, I.3
  • 12
    • 0026078019 scopus 로고
    • The ESTRO Breur lecture. Cellular sensitivity to low dose-rate irradiation focuses the problem of tumour radioresistance
    • G.G. Steel The ESTRO Breur lecture. Cellular sensitivity to low dose-rate irradiation focuses the problem of tumour radioresistance Radiother Oncol 20 1991 71 83
    • (1991) Radiother Oncol , vol.20 , pp. 71-83
    • Steel, G.G.1
  • 13
    • 0042632901 scopus 로고    scopus 로고
    • Pathways of DNA double-strand break repair during the mammalian cell cycle
    • K. Rothkamm, I. Kruger, L.H. Thompson, and M. Lobrich Pathways of DNA double-strand break repair during the mammalian cell cycle Mol Cell Biol 23 2003 5706 5715
    • (2003) Mol Cell Biol , vol.23 , pp. 5706-5715
    • Rothkamm, K.1    Kruger, I.2    Thompson, L.H.3    Lobrich, M.4
  • 14
    • 3142768860 scopus 로고    scopus 로고
    • Conservative homologous recombination preferentially repairs DNA double-strand breaks in the S phase of the cell cycle in human cells
    • N. Saleh-Gohari, and T. Helleday Conservative homologous recombination preferentially repairs DNA double-strand breaks in the S phase of the cell cycle in human cells Nucleic Acids Res 32 2004 3683 3688
    • (2004) Nucleic Acids Res , vol.32 , pp. 3683-3688
    • Saleh-Gohari, N.1    Helleday, T.2
  • 15
    • 70350763838 scopus 로고    scopus 로고
    • ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
    • A. Beucher, J. Birraux, and L. Tchouandong ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2 EMBO J 28 2009 3413 3427
    • (2009) EMBO J , vol.28 , pp. 3413-3427
    • Beucher, A.1    Birraux, J.2    Tchouandong, L.3
  • 16
    • 0020585842 scopus 로고
    • Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell
    • T.D. Stamato, R. Weinstein, A. Giaccia, and L. Mackenzie Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell Somatic Cell Genet 9 1983 165 173
    • (1983) Somatic Cell Genet , vol.9 , pp. 165-173
    • Stamato, T.D.1    Weinstein, R.2    Giaccia, A.3    Mackenzie, L.4
  • 17
    • 0024368474 scopus 로고
    • Cell cycle responses of two X-ray sensitive mutants defective in DNA repair
    • G.F. Whitmore, A.J. Varghese, and S. Gulyas Cell cycle responses of two X-ray sensitive mutants defective in DNA repair Int J Radiat Biol 56 1989 657 665
    • (1989) Int J Radiat Biol , vol.56 , pp. 657-665
    • Whitmore, G.F.1    Varghese, A.J.2    Gulyas, S.3
  • 18
    • 0028832369 scopus 로고
    • The genetic basis of cellular recovery from radiation damage: Response of the radiosensitive irs lines to low-dose-rate irradiation
    • J. Thacker, and R.E. Wilkinson The genetic basis of cellular recovery from radiation damage: response of the radiosensitive irs lines to low-dose-rate irradiation Radiat Res 144 1995 294 300
    • (1995) Radiat Res , vol.144 , pp. 294-300
    • Thacker, J.1    Wilkinson, R.E.2
  • 19
    • 0035872477 scopus 로고    scopus 로고
    • Radiation-induced genomic rearrangements formed by nonhomologous end-joining of DNA double-strand breaks
    • K. Rothkamm, M. Kuhne, P.A. Jeggo, and M. Lobrich Radiation-induced genomic rearrangements formed by nonhomologous end-joining of DNA double-strand breaks Cancer Res 61 2001 3886 3893
    • (2001) Cancer Res , vol.61 , pp. 3886-3893
    • Rothkamm, K.1    Kuhne, M.2    Jeggo, P.A.3    Lobrich, M.4
  • 20
    • 2542595443 scopus 로고    scopus 로고
    • Enhanced fidelity for rejoining radiation-induced DNA double-strand breaks in the G2 phase of Chinese hamster ovary cells
    • I. Kruger, K. Rothkamm, and M. Lobrich Enhanced fidelity for rejoining radiation-induced DNA double-strand breaks in the G2 phase of Chinese hamster ovary cells Nucleic Acids Res 32 2004 2677 2684
    • (2004) Nucleic Acids Res , vol.32 , pp. 2677-2684
    • Kruger, I.1    Rothkamm, K.2    Lobrich, M.3
  • 21
    • 0018877553 scopus 로고
    • Validation of conditions for efficient detection of HPRT and APRT mutations in suspension-cultured Chinese hamster ovary cells
    • L.H. Thompson, S. Fong, and K. Brookman Validation of conditions for efficient detection of HPRT and APRT mutations in suspension-cultured Chinese hamster ovary cells Mutat Res 74 1980 21 36
    • (1980) Mutat Res , vol.74 , pp. 21-36
    • Thompson, L.H.1    Fong, S.2    Brookman, K.3
  • 22
    • 0023905947 scopus 로고
    • A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication
    • L.F. Fuller, and R.B. Painter A Chinese hamster ovary cell line hypersensitive to ionizing radiation and deficient in repair replication Mutat Res 193 1988 109 121
    • (1988) Mutat Res , vol.193 , pp. 109-121
    • Fuller, L.F.1    Painter, R.B.2
  • 23
    • 0032061317 scopus 로고    scopus 로고
    • XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages
    • N. Liu, J.E. Lamerdin, and R.S. Tebbs XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages Mol Cell 1 1998 783 793
    • (1998) Mol Cell , vol.1 , pp. 783-793
    • Liu, N.1    Lamerdin, J.E.2    Tebbs, R.S.3
  • 24
    • 0028960511 scopus 로고
    • Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation
    • T. Blunt, N.J. Finnie, and G.E. Taccioli Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation Cell 80 1995 813 823
    • (1995) Cell , vol.80 , pp. 813-823
    • Blunt, T.1    Finnie, N.J.2    Taccioli, G.E.3
  • 25
    • 0019956767 scopus 로고
    • A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange
    • L.H. Thompson, K.W. Brookman, and L.E. Dillehay A CHO-cell strain having hypersensitivity to mutagens, a defect in DNA strand-break repair, and an extraordinary baseline frequency of sister-chromatid exchange Mutat Res 95 1982 427 440
    • (1982) Mutat Res , vol.95 , pp. 427-440
    • Thompson, L.H.1    Brookman, K.W.2    Dillehay, L.E.3
  • 26
    • 77950842499 scopus 로고    scopus 로고
    • A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown
    • G.S. Higgins, R. Prevo, and Y.F. Lee A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown Cancer Res 70 2010 2984 2993
    • (2010) Cancer Res , vol.70 , pp. 2984-2993
    • Higgins, G.S.1    Prevo, R.2    Lee, Y.F.3
  • 27
    • 48649096069 scopus 로고    scopus 로고
    • Class i PI3 kinase inhibition by the pyridinylfuranopyrimidine inhibitor PI-103 enhances tumor radiosensitivity
    • R. Prevo, E. Deutsch, and O. Sampson Class I PI3 kinase inhibition by the pyridinylfuranopyrimidine inhibitor PI-103 enhances tumor radiosensitivity Cancer Res 68 2008 5915 5923
    • (2008) Cancer Res , vol.68 , pp. 5915-5923
    • Prevo, R.1    Deutsch, E.2    Sampson, O.3
  • 28
    • 0034739853 scopus 로고    scopus 로고
    • P53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
    • L.B. Schultz, N.H. Chehab, A. Malikzay, and T.D. Halazonetis P53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks J Cell Biol 151 2000 1381 1390
    • (2000) J Cell Biol , vol.151 , pp. 1381-1390
    • Schultz, L.B.1    Chehab, N.H.2    Malikzay, A.3    Halazonetis, T.D.4
  • 29
    • 0035796042 scopus 로고    scopus 로고
    • Homologous recombinational repair of DNA ensures mammalian chromosome stability
    • L.H. Thompson, and D. Schild Homologous recombinational repair of DNA ensures mammalian chromosome stability Mutat Res 477 2001 131 153
    • (2001) Mutat Res , vol.477 , pp. 131-153
    • Thompson, L.H.1    Schild, D.2
  • 30
    • 80655127826 scopus 로고    scopus 로고
    • The role of homologous recombination in radiation-induced double-strand break repair
    • P.A. Jeggo, V. Geuting, and M. Lobrich The role of homologous recombination in radiation-induced double-strand break repair Radiother Oncol 101 2011 7 12
    • (2011) Radiother Oncol , vol.101 , pp. 7-12
    • Jeggo, P.A.1    Geuting, V.2    Lobrich, M.3
  • 31
    • 10044275229 scopus 로고
    • X-ray damage and recovery in mammalian cells in culture
    • M.M. Elkind, and H. Sutton X-ray damage and recovery in mammalian cells in culture Nature 184 1959 1293 1295
    • (1959) Nature , vol.184 , pp. 1293-1295
    • Elkind, M.M.1    Sutton, H.2
  • 34
    • 33846860888 scopus 로고    scopus 로고
    • Split dose recovery studies using homologous recombination deficient gene knockout chicken B lymphocyte cells
    • B.S. Rao, K. Tano, S. Takeda, and H. Utsumi Split dose recovery studies using homologous recombination deficient gene knockout chicken B lymphocyte cells J Radiat Res (Tokyo) 48 2007 77 85
    • (2007) J Radiat Res (Tokyo) , vol.48 , pp. 77-85
    • Rao, B.S.1    Tano, K.2    Takeda, S.3    Utsumi, H.4
  • 35
    • 0344286677 scopus 로고    scopus 로고
    • Joining of correct and incorrect DNA double-strand break ends in normal human and ataxia telangiectasia fibroblasts
    • M. Lobrich, M. Kuhne, J. Wetzel, and K. Rothkamm Joining of correct and incorrect DNA double-strand break ends in normal human and ataxia telangiectasia fibroblasts Genes Chromosomes Cancer 27 2000 59 68
    • (2000) Genes Chromosomes Cancer , vol.27 , pp. 59-68
    • Lobrich, M.1    Kuhne, M.2    Wetzel, J.3    Rothkamm, K.4
  • 36
    • 2142712163 scopus 로고    scopus 로고
    • No dose-dependence of DNA double-strand break misrejoining following alpha-particle irradiation
    • M. Kuhne, K. Rothkamm, and M. Lobrich No dose-dependence of DNA double-strand break misrejoining following alpha-particle irradiation Int J Radiat Biol 76 2000 891 900
    • (2000) Int J Radiat Biol , vol.76 , pp. 891-900
    • Kuhne, M.1    Rothkamm, K.2    Lobrich, M.3
  • 37
    • 0036676638 scopus 로고    scopus 로고
    • Misrepair of radiation-induced DNA double-strand breaks and its relevance for tumorigenesis and cancer treatment (review)
    • K. Rothkamm, and M. Lobrich Misrepair of radiation-induced DNA double-strand breaks and its relevance for tumorigenesis and cancer treatment (review) Int J Oncol 21 2002 433 440
    • (2002) Int J Oncol , vol.21 , pp. 433-440
    • Rothkamm, K.1    Lobrich, M.2
  • 38
    • 77449141863 scopus 로고    scopus 로고
    • Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin
    • C. Bauerschmidt, C. Arrichiello, and S. Burdak-Rothkamm Cohesin promotes the repair of ionizing radiation-induced DNA double-strand breaks in replicated chromatin Nucleic Acids Res 38 2010 477 487
    • (2010) Nucleic Acids Res , vol.38 , pp. 477-487
    • Bauerschmidt, C.1    Arrichiello, C.2    Burdak-Rothkamm, S.3
  • 39
    • 13044313472 scopus 로고    scopus 로고
    • Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1
    • O. White, J.A. Eisen, and J.F. Heidelberg Genome sequence of the radioresistant bacterium Deinococcus radiodurans R1 Science 286 1999 1571 1577
    • (1999) Science , vol.286 , pp. 1571-1577
    • White, O.1    Eisen, J.A.2    Heidelberg, J.F.3
  • 40
    • 84866936319 scopus 로고    scopus 로고
    • The relationship between homologous recombination repair and the sensitivity of human epidermis to the size of daily doses over a 5-week course of breast radiotherapy
    • N. Somaiah, J. Yarnold, and F. Daley The relationship between homologous recombination repair and the sensitivity of human epidermis to the size of daily doses over a 5-week course of breast radiotherapy Clin Cancer Res 18 2012 5479 5488
    • (2012) Clin Cancer Res , vol.18 , pp. 5479-5488
    • Somaiah, N.1    Yarnold, J.2    Daley, F.3
  • 41
    • 0024314422 scopus 로고
    • Repair capacity and kinetics of human skin during fractionated radiotherapy: Erythema, desquamation, and telangiectasia after 3 and 5 year's follow-up
    • I. Turesson, and H.D. Thames Repair capacity and kinetics of human skin during fractionated radiotherapy: erythema, desquamation, and telangiectasia after 3 and 5 year's follow-up Radiother Oncol 15 1989 169 188
    • (1989) Radiother Oncol , vol.15 , pp. 169-188
    • Turesson, I.1    Thames, H.D.2
  • 42
    • 0142209201 scopus 로고    scopus 로고
    • Time factor for acute tissue reactions following fractionated irradiation: A balance between repopulation and enhanced radiosensitivity
    • J.W. Hopewell, J. Nyman, and I. Turesson Time factor for acute tissue reactions following fractionated irradiation: a balance between repopulation and enhanced radiosensitivity Int J Radiat Biol 79 2003 513 524
    • (2003) Int J Radiat Biol , vol.79 , pp. 513-524
    • Hopewell, J.W.1    Nyman, J.2    Turesson, I.3
  • 44
    • 4944229642 scopus 로고    scopus 로고
    • Hallmarks of 'BRCAness' in sporadic cancers
    • N. Turner, A. Tutt, and A. Ashworth Hallmarks of 'BRCAness' in sporadic cancers Nat Rev Cancer 4 2004 814 819
    • (2004) Nat Rev Cancer , vol.4 , pp. 814-819
    • Turner, N.1    Tutt, A.2    Ashworth, A.3
  • 45
    • 77956633760 scopus 로고    scopus 로고
    • Prediction of breast cancer sensitivity to neoadjuvant chemotherapy based on status of DNA damage repair proteins
    • H. Asakawa, H. Koizumi, and A. Koike Prediction of breast cancer sensitivity to neoadjuvant chemotherapy based on status of DNA damage repair proteins Breast Cancer Res 12 2010 R17
    • (2010) Breast Cancer Res , vol.12 , pp. 17
    • Asakawa, H.1    Koizumi, H.2    Koike, A.3
  • 46
    • 77958045536 scopus 로고    scopus 로고
    • A marker of homologous recombination predicts pathological complete response to neoadjuvant chemotherapy in primary breast cancer
    • M.K. Graeser, A. McCarthy, and C.J. Lord A marker of homologous recombination predicts pathological complete response to neoadjuvant chemotherapy in primary breast cancer Clin Cancer Res 16 2010 6159 6168
    • (2010) Clin Cancer Res , vol.16 , pp. 6159-6168
    • Graeser, M.K.1    McCarthy, A.2    Lord, C.J.3


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