Pharmacokinetics and tolerance of toal astragalosides after intravenous infusion of astragalosides injection in healthy Chinese volunteers

Phytomedicine

Volumn 20, Issue 12, 2013, Pages 1105-1111

  Xu, Meijuan ^a,b   Yin, Jungang ^a   Xie, Liyan ^a   Zhang, Jun ^a   Zou, Chong ^a   Zou, Jiandong ^a   Liu, Fang ^a   Ju, Wenzheng ^a   Li, Ping ^b  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Astragaloside IV (AGS IV); Human; Pharmacokinetics; Radix Astragali; Tolerance; Total astragalosides

Indexed keywords

BILIRUBIN; HERBACEOUS AGENT; TOTAL ASTRAGALOSIDES; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; DISTRIBUTION VOLUME; DRUG BLOOD LEVEL; DRUG DOSE ESCALATION; DRUG ELIMINATION; DRUG EXCRETION; DRUG HALF LIFE; DRUG SAFETY; DRUG TOLERANCE; FEMALE; FEVER; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RASH; REPEATED DRUG DOSE; SIDE EFFECT; SINGLE BLIND PROCEDURE; SINGLE DRUG DOSE; STEADY STATE; TIME TO MAXIMUM PLASMA CONCENTRATION; UPPER RESPIRATORY TRACT INFECTION; URINALYSIS; URINARY EXCRETION;

ASTRAGALOSIDE IV (AGS-IV); HUMAN; PHARMACOKINETICS; RADIX ASTRAGALI; TOLERANCE; TOTAL ASTRAGALOSIDES;

ADULT; ANGELICA SINENSIS; ASIAN CONTINENTAL ANCESTRY GROUP; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HEALTHY VOLUNTEERS; HUMANS; INFUSIONS, INTRAVENOUS; MALE; SAPONINS; TIME FACTORS; TRITERPENES; YOUNG ADULT;

EID: 84883144802     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2013.05.004     Document Type: Article

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