Effect of asbestos exposure on differentiation of cytotoxic t lymphocytes in mixed lymphocyte reaction of human peripheral blood mononuclear cells

American Journal of Respiratory Cell and Molecular Biology

Volumn 49, Issue 1, 2013, Pages 28-36

  Kumagai Takei, Naoko ^a   Nishimura, Yasumitsu ^a   Maeda, Megumi ^a,b   Hayashi, Hiroaki ^a   Matsuzaki, Hidenori ^a   Lee, Suni ^a   Hiratsuka, Junichi ^a   Otsuki, Takemi ^a  

^a KAWASAKI MEDICAL SCHOOL   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

Author keywords

Asbestos; Cytotoxic T lymphocytes; Granzyme B; IFN ; TNF

Indexed keywords

ASBESTOS; CD3 ANTIGEN; CD45RA ANTIGEN; CD45RO ANTIGEN; CD8 ANTIGEN; CHRYSOTILE; CROCIDOLITE; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 2 RECEPTOR ALPHA; LIPOCORTIN 5; LYMPHOCYTE SURFACE MARKER; NATURAL KILLER CELL RECEPTOR NKG2D; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CD25+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MEDIATED CYTOTOXICITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXIC T LYMPHOCYTE; DISEASE ASSOCIATION; EFFECTOR CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; MIXED LYMPHOCYTE REACTION; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION;

APOPTOSIS; ASBESTOS, CROCIDOLITE; ASBESTOS, SERPENTINE; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL PROLIFERATION; GRANZYMES; HUMANS; INTERFERON-GAMMA; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE COUNT; LYMPHOCYTE CULTURE TEST, MIXED; T-LYMPHOCYTES, CYTOTOXIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84883139223     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0134OC     Document Type: Article

References (38)

1. Sporn TA, Roggli VL. Mesothelioma. In: Roggli VL, Oury TD, Sporn TA, editors. Asbestos-associated diseases. New York: Springer-Verlag; 2004. pp. 104-168.
2. Mossman BT, Kamp DW, Weitzman SA. Mechanisms of carcinogenesis and clinical features of asbestos-associated cancers. Cancer Invest 1996;14:466-480.
3. Dusinska M, Collins A, Kazimirova A, Barancokova M, Harrington V, Volkovova K, Staruchova M, Horska A, Wsolova L, Kocan A, et al. Genotoxic effects of asbestos in humans. Mutat Res 2004;553:91-102.
4. Topinka J, Loli P, Georgiadis P, DusinskaM, HurbankovaM, Kovacikova Z, Volkovova K, Kazimirova A, Barancokova M, Tatrai E, et al. Mutagenesis by asbestos in the lung of lambda-lacI transgenic rats. Mutat Res 2004;553:67-78.
5. McDonald AD, McDonald JC. Mesothelioma after crocidolite exposure during gas mask manufacture. Environ Res 1978;17:340-346.
6. Selikoff IJ, Hammond EC, Seidman H. Mortality experience of insulation workers in the United States and Canada, 1943-1976. Ann N Y Acad Sci 1979;330:91-116.
7. Selikoff IJ, Hammond EC, Seidman H. Latency of asbestos disease among insulation workers in the United States and Canada. Cancer 1980;46:2736-2740.
8. Nishimura Y, Miura Y, Maeda M, Kumagai N, Murakami S, Hayashi, et al. Impairment in cytotoxicity and expression of NK cell-activating receptors on human NK cells following exposure to asbestos fibers. Int J Immunopathol Pharmacol 2009;22:579-590.
9. Nishimura Y, Maeda M, Kumagai N, Hayashi H, Miura Y, Otsuki T. Decrease in phosphorylation of ERK following decreased expression of NK cell-activating receptors in human NK cell line exposed to asbestos. Int J Immunopathol Pharmacol 2009;22:879-888.
10. Miura Y, Nishimura Y, Katsuyama H, Maeda M, Hayashi H, Dong M, Hyodoh F, Tomita M, Matsuo Y, Uesaka A, et al. Involvement of IL-10 and Bcl-2 in resistance against an asbestos-induced apoptosis of T cells. Apoptosis 2006;11:1825-1835.
11. Miura Y, Nishimura Y, Maeda M, Murakami S, Hayashi H, Fukuoka K, Kishimoto T, Nakano T, Otsuki T. Immunological alterations found in mesothelioma patients and supporting experimental evidence. Environ Health Prev Med 2008;13:55-59.
12. Otsuki T, Maeda M, Murakami S, Hayashi H, Miura Y, Kusaka M, Nakano T, Fukuoka K, Kishimoto T, Hyodoh F, et al. Immunological effects of silica and asbestos. Cell Mol Immunol 2007;4:261-268.
13. Maeda M, Nishimura Y, Hayashi H, Kumagai N, Chen Y, Murakami S, Miura Y, Hiratsuka J, Kishimoto T, Otsuki T. Reduction of CXC chemokine receptor 3 in an in vitro model of continuous exposure to asbestos in a human T-cell line, MT-2. Am J Respir Cell Mol Biol 2011;45:470-479.
14. Banchereau J, Palucka AK. Dendritic cells as therapeutic vaccines against cancer. Nat Rev Immunol 2005;5:296-306.
15. Harty JT, Tvinnereim AR, White DW. CD81 T cell effector mechanisms in resistance to infection. Annu Rev Immunol 2000;18:275-308.
16. Catalfamo M, Henkart PA. Perforin and the granule exocytosis cytotoxicity pathway. Curr Opin Immunol 2003;15:522-527.
17. Yamada N, Oizumi S, Kikuchi E, Shinagawa N, Konishi-Sakakibara J, Ishimine A, Aoe K, Gemba K. Kishimoto T, Torigoe T, et al. CD8 (1) tumor-infiltrating lymphocytes predict favorable prognosis in malignant pleural mesothelioma after resection. Cancer Immunol Immunother 2010;59:1543-1549.
18. Rentenaar RJ, Vosters JL, van Diepen FN, Remmerswaal EB, van Lier RA, ten Berge IJ. Differentiation of human alloreactive CD8(1) T cells in vitro. Immunology 2002;105:278-285.
19. Melief CJ, de Waal LP, van der MeulenMY, Melvold RW, Kohn HI. Fine specificity of alloimmune cytotoxic T lymphocytes directed against H-2K: a study with Kb mutants. J Exp Med 1980;151:993-1013.
20. Bluman EM, Schnier GS, Avalos BR, Strout MP, Sultan H, Jacobson FW, Williams DE, Carson WE, Caligiuri MA. The c-kit ligand potentiates the allogeneic mixed lymphocyte reaction. Blood 1996;88:3887-3893.
21. Kohyama N, Shinohara Y, Suzuki Y. Mineral phases and some reexamined characteristics of the International Union Against Cancer standard asbestos samples. Am J Ind Med 1996;30:515-528.
22. Verneris MR, Karami M, Baker J, Jayaswal A, Negrin RS. Role of NKG2D signaling in the cytotoxicity of activated and expanded CD81 T cells. Blood 2004;103:3065-3072.
23. Zhang S, Zhang H, Zhao J. The role of CD4 T cell help for CD8 CTL activation. Biochem Biophys Res Commun 2009;384:405-408.
24. Cox MA, Harrington LE, Zajac AJ. Cytokines and the inception of CD8 T cell responses. Trends Immunol 2011;32:180-186.
25. Brossart P, BevanMJ. Presentation of exogenous protein antigens onmajor histocompatibility complex class I molecules by dendritic cells: pathway of presentation and regulation by cytokines. Blood 1997;90:1594-1599.
26. Groux H, Bigler M, de Vries JE, Roncarolo MG. Inhibitory and stimulatory effects of IL-10 on human CD81 T cells. J Immunol 1998;160:3188-3193.
27. Heintz NH, Janssen-Heininger YM, Mossman BT. Asbestos, lung cancers, and mesotheliomas: from molecular approaches to targeting tumor survival pathways. Am J Respir Cell Mol Biol 2010;42:133-139.
28. Hughes JM,Weill H, Hammad YY.Mortality of workers employed in two asbestos cement manufacturing plants. Br J Ind Med 1987;44:161-174.
29. Jiang L, Nagai H, Ohara H, Hara S, Tachibana M, Hirano S, Shinohara Y, Kohyama N, Akatsuka S, Toyokuni S. Characteristics and modifying factors of asbestos-induced oxidative DNA damage. Cancer Sci 2008;99: 2142-2151.
30. Bolton RE, Davis JM, Donaldson K, Wright A. Variations in the carcinogenicity of mineral fibres. Ann Occup Hyg 1982;26:569-582.
31. Davis JM, Addison J, Bolton RE, Donaldson K, Jones AD. Inhalation and injection studies in rats using dust samples from chrysotile asbestos prepared by a wet dispersion process. Br J Exp Pathol 1986;67:113-129.
32. Nagai H, Ishihara T, LeeWH, Ohara H, Okazaki Y,Okawa K, Toyokuni S. Asbestos surface provides a niche for oxidative modification. Cancer Sci 2011;102:2118-2125.
33. Aikoh T, Tomokuni A, Matsukii T, Hyodoh F, Ueki H, Otsuki T, Ueki A. Activation-induced cell death in human peripheral blood lymphocytes after stimulation with silicate in vitro. Int J Oncol 1998;12:1355-1359.
34. D'Souza WN, Lefrancois L. IL-2 is not required for the initiation of CD8 T cell cycling but sustains expansion. J Immunol 2003;171:5727-5735.
35. Heath WR, Carbone FR. Cross-presentation in viral immunity and selftolerance. Nat Rev Immunol 2001;1:126-134.
36. Dodson RF,Williams MG Jr., Corn CJ, Brollo A, Bianchi C. A comparison of asbestos burden in lung parenchyma, lymph nodes, and plaques. Ann N Y Acad Sci 1991;643:53-60.
37. Miserocchi G, Sancini G, Mantegazza F, Chiappino G. Translocation pathways for inhaled asbestos fibers. Environ Health 2008;7:4.
38. Griffith DE, Miller EJ, Gray LD, Idell S, Johnson AR. Interleukin-1-mediated release of interleukin-8 by asbestos-stimulated human pleural mesothelial cells. Am J Respir Cell Mol Biol 1994;10:245-252.