-
1
-
-
0034608816
-
In vitro cultivation of human islets from expanded ductal tissue
-
Bonner-Weir S, Taneja M, Weir GC, Tatarkiewicz K, Song KH, et al. (2000) In vitro cultivation of human islets from expanded ductal tissue. Proc Natl Acad Sci U S A 97: 7999-8004.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 7999-8004
-
-
Bonner-Weir, S.1
Taneja, M.2
Weir, G.C.3
Tatarkiewicz, K.4
Song, K.H.5
-
2
-
-
34347384162
-
Differentiation of affinity-purified human pancreatic duct cells to beta-cells
-
Yatoh S, Dodge R, Akashi T, Omer A, Sharma A, et al. (2007) Differentiation of affinity-purified human pancreatic duct cells to beta-cells. Diabetes 56: 1802-1809.
-
(2007)
Diabetes
, vol.56
, pp. 1802-1809
-
-
Yatoh, S.1
Dodge, R.2
Akashi, T.3
Omer, A.4
Sharma, A.5
-
3
-
-
77957606887
-
Beta-cell growth and regeneration: replication is only part of the story
-
Bonner-Weir S, Li WC, Ouziel-Yahalom L, Guo L, Weir GC, et al. (2010) Beta-cell growth and regeneration: replication is only part of the story. Diabetes 59: 2340-2348.
-
(2010)
Diabetes
, vol.59
, pp. 2340-2348
-
-
Bonner-Weir, S.1
Li, W.C.2
Ouziel-Yahalom, L.3
Guo, L.4
Weir, G.C.5
-
4
-
-
77951611220
-
Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss
-
Thorel F, Nepote V, Avril I, Kohno K, Desgraz R, et al. (2010) Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss. Nature 464: 1149-1154.
-
(2010)
Nature
, vol.464
, pp. 1149-1154
-
-
Thorel, F.1
Nepote, V.2
Avril, I.3
Kohno, K.4
Desgraz, R.5
-
6
-
-
0027449197
-
A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development
-
Bonner-Weir S, Baxter LA, Schuppin GT, Smith FE, (1993) A second pathway for regeneration of adult exocrine and endocrine pancreas. A possible recapitulation of embryonic development. Diabetes 42: 1715-1720.
-
(1993)
Diabetes
, vol.42
, pp. 1715-1720
-
-
Bonner-Weir, S.1
Baxter, L.A.2
Schuppin, G.T.3
Smith, F.E.4
-
7
-
-
0027276885
-
Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice
-
Gu D, Sarvetnick N, (1993) Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice. Development 118: 33-46.
-
(1993)
Development
, vol.118
, pp. 33-46
-
-
Gu, D.1
Sarvetnick, N.2
-
8
-
-
77956004353
-
Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats
-
Li WC, Rukstalis JM, Nishimura W, Tchipashvili V, Habener JF, et al. (2010) Activation of pancreatic-duct-derived progenitor cells during pancreas regeneration in adult rats. J Cell Sci 123: 2792-2802.
-
(2010)
J Cell Sci
, vol.123
, pp. 2792-2802
-
-
Li, W.C.1
Rukstalis, J.M.2
Nishimura, W.3
Tchipashvili, V.4
Habener, J.F.5
-
9
-
-
38749108893
-
Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas
-
Xu X, D'Hoker J, Stange G, Bonne S, De Leu N, et al. (2008) Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas. Cell 132: 197-207.
-
(2008)
Cell
, vol.132
, pp. 197-207
-
-
Xu, X.1
D'Hoker, J.2
Stange, G.3
Bonne, S.4
De Leu, N.5
-
10
-
-
58149378342
-
Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth
-
Inada A, Nienaber C, Katsuta H, Fujitani Y, Levine J, et al. (2008) Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth. Proc Natl Acad Sci U S A 105: 19915-19919.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 19915-19919
-
-
Inada, A.1
Nienaber, C.2
Katsuta, H.3
Fujitani, Y.4
Levine, J.5
-
11
-
-
71649092364
-
Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth
-
Solar M, Cardalda C, Houbracken I, Martin M, Maestro MA, et al. (2009) Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth. Dev Cell 17: 849-860.
-
(2009)
Dev Cell
, vol.17
, pp. 849-860
-
-
Solar, M.1
Cardalda, C.2
Houbracken, I.3
Martin, M.4
Maestro, M.A.5
-
12
-
-
79951539242
-
Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas
-
Kopp JL, Dubois CL, Schaffer AE, Hao E, Shih HP, et al. (2011) Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas. Development 138: 653-665.
-
(2011)
Development
, vol.138
, pp. 653-665
-
-
Kopp, J.L.1
Dubois, C.L.2
Schaffer, A.E.3
Hao, E.4
Shih, H.P.5
-
13
-
-
42949160019
-
The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting
-
Winkles JA, (2008) The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting. Nat Rev Drug Discov 7: 411-425.
-
(2008)
Nat Rev Drug Discov
, vol.7
, pp. 411-425
-
-
Winkles, J.A.1
-
14
-
-
80054865852
-
TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses
-
Burkly LC, Michaelson JS, Zheng TS, (2011) TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses. Immunol Rev 244: 99-114.
-
(2011)
Immunol Rev
, vol.244
, pp. 99-114
-
-
Burkly, L.C.1
Michaelson, J.S.2
Zheng, T.S.3
-
15
-
-
36049022442
-
TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease
-
Burkly LC, Michaelson JS, Hahm K, Jakubowski A, Zheng TS, (2007) TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease. Cytokine 40: 1-16.
-
(2007)
Cytokine
, vol.40
, pp. 1-16
-
-
Burkly, L.C.1
Michaelson, J.S.2
Hahm, K.3
Jakubowski, A.4
Zheng, T.S.5
-
16
-
-
24644478033
-
TWEAK induces liver progenitor cell proliferation
-
Jakubowski A, Ambrose C, Parr M, Lincecum JM, Wang MZ, et al. (2005) TWEAK induces liver progenitor cell proliferation. J Clin Invest 115: 2330-2340.
-
(2005)
J Clin Invest
, vol.115
, pp. 2330-2340
-
-
Jakubowski, A.1
Ambrose, C.2
Parr, M.3
Lincecum, J.M.4
Wang, M.Z.5
-
17
-
-
57349112286
-
Generation and Regeneration of Cells of the Liver and Pancreas
-
Zaret KS, Grompe M, (2008) Generation and Regeneration of Cells of the Liver and Pancreas. Science 322: 1490-1494.
-
(2008)
Science
, vol.322
, pp. 1490-1494
-
-
Zaret, K.S.1
Grompe, M.2
-
18
-
-
33845689427
-
TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration
-
Girgenrath M, Weng S, Kostek CA, Browning B, Wang M, et al. (2006) TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration. Embo J 25: 5826-5839.
-
(2006)
Embo J
, vol.25
, pp. 5826-5839
-
-
Girgenrath, M.1
Weng, S.2
Kostek, C.A.3
Browning, B.4
Wang, M.5
-
19
-
-
31144452060
-
Proinflammatory effects of TWEAK/Fn14 interactions in glomerular mesangial cells
-
Campbell S, Burkly LC, Gao HX, Berman JW, Su L, et al. (2006) Proinflammatory effects of TWEAK/Fn14 interactions in glomerular mesangial cells. J Immunol 176: 1889-1898.
-
(2006)
J Immunol
, vol.176
, pp. 1889-1898
-
-
Campbell, S.1
Burkly, L.C.2
Gao, H.X.3
Berman, J.W.4
Su, L.5
-
20
-
-
33750300516
-
Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome
-
Tran NL, McDonough WS, Savitch BA, Fortin SP, Winkles JA, et al. (2006) Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome. Cancer Res 66: 9535-9542.
-
(2006)
Cancer Res
, vol.66
, pp. 9535-9542
-
-
Tran, N.L.1
McDonough, W.S.2
Savitch, B.A.3
Fortin, S.P.4
Winkles, J.A.5
-
21
-
-
79960091768
-
Development of an Fn14 agonistic antibody as an anti-tumor agent
-
Michaelson JS, Amatucci A, Kelly R, Su L, Garber E, et al. (2011) Development of an Fn14 agonistic antibody as an anti-tumor agent. MAbs 3: 362-375.
-
(2011)
MAbs
, vol.3
, pp. 362-375
-
-
Michaelson, J.S.1
Amatucci, A.2
Kelly, R.3
Su, L.4
Garber, E.5
-
22
-
-
0022499226
-
Nonspecific immunocytochemical reactions with certain neurohormonal peptides and basic peptide sequences
-
Scopsi L, Wang BL, Larsson LI, (1986) Nonspecific immunocytochemical reactions with certain neurohormonal peptides and basic peptide sequences. J Histochem Cytochem 34: 1469-1475.
-
(1986)
J Histochem Cytochem
, vol.34
, pp. 1469-1475
-
-
Scopsi, L.1
Wang, B.L.2
Larsson, L.I.3
-
23
-
-
0036196767
-
Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies
-
Chicheportiche Y, Chicheportiche R, Sizing I, Thompson J, Benjamin CB, et al. (2002) Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies. Arthritis Res 4: 126-133.
-
(2002)
Arthritis Res
, vol.4
, pp. 126-133
-
-
Chicheportiche, Y.1
Chicheportiche, R.2
Sizing, I.3
Thompson, J.4
Benjamin, C.B.5
-
24
-
-
0037080352
-
Multiple pathways of TWEAK-induced cell death
-
Nakayama M, Ishidoh K, Kayagaki N, Kojima Y, Yamaguchi N, et al. (2002) Multiple pathways of TWEAK-induced cell death. J Immunol 168: 734-743.
-
(2002)
J Immunol
, vol.168
, pp. 734-743
-
-
Nakayama, M.1
Ishidoh, K.2
Kayagaki, N.3
Kojima, Y.4
Yamaguchi, N.5
-
25
-
-
0034652287
-
neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas
-
Gradwohl G, Dierich A, LeMeur M, Guillemot F, (2000) neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas. Proc Natl Acad Sci U S A 97: 1607-1611.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 1607-1611
-
-
Gradwohl, G.1
Dierich, A.2
LeMeur, M.3
Guillemot, F.4
-
26
-
-
0033825383
-
Expression of neurogenin3 reveals an islet cell precursor population in the pancreas
-
Schwitzgebel VM, Scheel DW, Conners JR, Kalamaras J, Lee JE, et al. (2000) Expression of neurogenin3 reveals an islet cell precursor population in the pancreas. Development 127: 3533-3542.
-
(2000)
Development
, vol.127
, pp. 3533-3542
-
-
Schwitzgebel, V.M.1
Scheel, D.W.2
Conners, J.R.3
Kalamaras, J.4
Lee, J.E.5
-
27
-
-
0036340074
-
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
-
Gu G, Dubauskaite J, Melton DA, (2002) Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors. Development 129: 2447-2457.
-
(2002)
Development
, vol.129
, pp. 2447-2457
-
-
Gu, G.1
Dubauskaite, J.2
Melton, D.A.3
-
28
-
-
0037002096
-
Pancreatic cell lineage analyses in mice
-
Herrera PL, Nepote V, Delacour A, (2002) Pancreatic cell lineage analyses in mice. Endocrine 19: 267-278.
-
(2002)
Endocrine
, vol.19
, pp. 267-278
-
-
Herrera, P.L.1
Nepote, V.2
Delacour, A.3
-
29
-
-
0020636495
-
Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release
-
Bonner-Weir S, Trent DF, Weir GC, (1983) Partial pancreatectomy in the rat and subsequent defect in glucose-induced insulin release. J Clin Invest 71: 1544-1553.
-
(1983)
J Clin Invest
, vol.71
, pp. 1544-1553
-
-
Bonner-Weir, S.1
Trent, D.F.2
Weir, G.C.3
-
30
-
-
0033009460
-
The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration
-
Sharma A, Zangen DH, Reitz P, Taneja M, Lissauer ME, et al. (1999) The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration. Diabetes 48: 507-513.
-
(1999)
Diabetes
, vol.48
, pp. 507-513
-
-
Sharma, A.1
Zangen, D.H.2
Reitz, P.3
Taneja, M.4
Lissauer, M.E.5
-
31
-
-
0345687862
-
Genes, signals, and lineages in pancreas development
-
Murtaugh LC, Melton DA, (2003) Genes, signals, and lineages in pancreas development. Annu Rev Cell Dev Biol 19: 71-89.
-
(2003)
Annu Rev Cell Dev Biol
, vol.19
, pp. 71-89
-
-
Murtaugh, L.C.1
Melton, D.A.2
-
32
-
-
0036730427
-
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
-
Kawaguchi Y, Cooper B, Gannon M, Ray M, MacDonald RJ, et al. (2002) The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors. Nat Genet 32: 128-134.
-
(2002)
Nat Genet
, vol.32
, pp. 128-134
-
-
Kawaguchi, Y.1
Cooper, B.2
Gannon, M.3
Ray, M.4
MacDonald, R.J.5
-
33
-
-
0034032317
-
Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas
-
Stoffers DA, Kieffer TJ, Hussain MA, Drucker DJ, Bonner-Weir S, et al. (2000) Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas. Diabetes 49: 741-748.
-
(2000)
Diabetes
, vol.49
, pp. 741-748
-
-
Stoffers, D.A.1
Kieffer, T.J.2
Hussain, M.A.3
Drucker, D.J.4
Bonner-Weir, S.5
-
34
-
-
0036326210
-
Exendin-4 differentiation of a human pancreatic duct cell line into endocrine cells: Involvement of PDX-1 and HNF3beta transcription factors
-
Zhou J, Pineyro MA, Wang X, Doyle ME, Egan JM, (2002) Exendin-4 differentiation of a human pancreatic duct cell line into endocrine cells: Involvement of PDX-1 and HNF3beta transcription factors. Journal of Cellular Physiology 192: 304-314.
-
(2002)
Journal of Cellular Physiology
, vol.192
, pp. 304-314
-
-
Zhou, J.1
Pineyro, M.A.2
Wang, X.3
Doyle, M.E.4
Egan, J.M.5
-
35
-
-
0027194337
-
Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells
-
Wang TC, Bonner-Weir S, Oates PS, Chulak M, Simon B, et al. (1993) Pancreatic gastrin stimulates islet differentiation of transforming growth factor alpha-induced ductular precursor cells. J Clin Invest 92: 1349-1356.
-
(1993)
J Clin Invest
, vol.92
, pp. 1349-1356
-
-
Wang, T.C.1
Bonner-Weir, S.2
Oates, P.S.3
Chulak, M.4
Simon, B.5
-
36
-
-
58149357117
-
Combination therapy with glucagon-like peptide-1 and gastrin restores normoglycemia in diabetic NOD mice
-
Suarez-Pinzon WL, Power RF, Yan Y, Wasserfall C, Atkinson M, et al. (2008) Combination therapy with glucagon-like peptide-1 and gastrin restores normoglycemia in diabetic NOD mice. Diabetes 57: 3281-3288.
-
(2008)
Diabetes
, vol.57
, pp. 3281-3288
-
-
Suarez-Pinzon, W.L.1
Power, R.F.2
Yan, Y.3
Wasserfall, C.4
Atkinson, M.5
-
37
-
-
10744222350
-
Analysis of expression profiles of islet-associated transcription and growth factors during beta-cell neogenesis from duct cells in partially duct-ligated mice
-
Li M, Miyagawa J, Moriwaki M, Yuan M, Yang Q, et al. (2003) Analysis of expression profiles of islet-associated transcription and growth factors during beta-cell neogenesis from duct cells in partially duct-ligated mice. Pancreas 27: 345-355.
-
(2003)
Pancreas
, vol.27
, pp. 345-355
-
-
Li, M.1
Miyagawa, J.2
Moriwaki, M.3
Yuan, M.4
Yang, Q.5
-
38
-
-
45849138144
-
Selective expansion of the {beta}-cell compartment in the pancreas of keratinocyte growth factor transgenic mice
-
Wagner M, Koschnick S, Beilke S, Frey M, Adler G, et al. (2008) Selective expansion of the {beta}-cell compartment in the pancreas of keratinocyte growth factor transgenic mice. Am J Physiol Gastrointest Liver Physiol 294: G1139-1147.
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.294
-
-
Wagner, M.1
Koschnick, S.2
Beilke, S.3
Frey, M.4
Adler, G.5
-
39
-
-
0033668752
-
Recombinant human betacellulin promotes the neogenesis of beta-cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion
-
Yamamoto K, Miyagawa J, Waguri M, Sasada R, Igarashi K, et al. (2000) Recombinant human betacellulin promotes the neogenesis of beta-cells and ameliorates glucose intolerance in mice with diabetes induced by selective alloxan perfusion. Diabetes 49: 2021-2027.
-
(2000)
Diabetes
, vol.49
, pp. 2021-2027
-
-
Yamamoto, K.1
Miyagawa, J.2
Waguri, M.3
Sasada, R.4
Igarashi, K.5
-
40
-
-
68349097448
-
Islet neogenesis-associated protein pentadecapeptide (INGAP-PP): mechanisms involved in its effect upon beta-cell mass and function
-
Madrid V, Del Zotto H, Maiztegui B, Raschia MA, Alzugaray ME, et al. (2009) Islet neogenesis-associated protein pentadecapeptide (INGAP-PP): mechanisms involved in its effect upon beta-cell mass and function. Regul Pept 157: 25-31.
-
(2009)
Regul Pept
, vol.157
, pp. 25-31
-
-
Madrid, V.1
Del Zotto, H.2
Maiztegui, B.3
Raschia, M.A.4
Alzugaray, M.E.5
-
41
-
-
84859046711
-
Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice
-
Reinert RB, Kantz J, Misfeldt AA, Poffenberger G, Gannon M, et al. (2012) Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice. PLoS One 7: e33529.
-
(2012)
PLoS One
, vol.7
-
-
Reinert, R.B.1
Kantz, J.2
Misfeldt, A.A.3
Poffenberger, G.4
Gannon, M.5
-
42
-
-
0028793314
-
Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats
-
Wang RN, Kloppel G, Bouwens L, (1995) Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats. Diabetologia 38: 1405-1411.
-
(1995)
Diabetologia
, vol.38
, pp. 1405-1411
-
-
Wang, R.N.1
Kloppel, G.2
Bouwens, L.3
-
43
-
-
0036266272
-
beta-cell neogenesis during prolonged hyperglycemia in rats
-
Lipsett M, Finegood DT, (2002) beta-cell neogenesis during prolonged hyperglycemia in rats. Diabetes 51: 1834-1841.
-
(2002)
Diabetes
, vol.51
, pp. 1834-1841
-
-
Lipsett, M.1
Finegood, D.T.2
-
44
-
-
18744394636
-
Tubular complexes as a source for islet neogenesis in the pancreas of diabetes-prone BB rats
-
Wang GS, Rosenberg L, Scott FW, (2005) Tubular complexes as a source for islet neogenesis in the pancreas of diabetes-prone BB rats. Lab Invest 85: 675-688.
-
(2005)
Lab Invest
, vol.85
, pp. 675-688
-
-
Wang, G.S.1
Rosenberg, L.2
Scott, F.W.3
-
45
-
-
63149088164
-
Trophic macrophages in development and disease
-
Pollard JW, (2009) Trophic macrophages in development and disease. Nat Rev Immunol 9: 259-270.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 259-270
-
-
Pollard, J.W.1
-
46
-
-
25644441744
-
Macrophages in the murine pancreas and their involvement in fetal endocrine development in vitro
-
Geutskens SB, Otonkoski T, Pulkkinen MA, Drexhage HA, Leenen PJ, (2005) Macrophages in the murine pancreas and their involvement in fetal endocrine development in vitro. J Leukoc Biol 78: 845-852.
-
(2005)
J Leukoc Biol
, vol.78
, pp. 845-852
-
-
Geutskens, S.B.1
Otonkoski, T.2
Pulkkinen, M.A.3
Drexhage, H.A.4
Leenen, P.J.5
-
47
-
-
0028566113
-
Effects of macrophage depletion at different times after treatment with ethylene dimethane sulfonate (EDS) on the regeneration of Leydig cells in the adult rat
-
Gaytan F, Bellido C, Morales C, Reymundo C, Aguilar E, et al. (1994) Effects of macrophage depletion at different times after treatment with ethylene dimethane sulfonate (EDS) on the regeneration of Leydig cells in the adult rat. J Androl 15: 558-564.
-
(1994)
J Androl
, vol.15
, pp. 558-564
-
-
Gaytan, F.1
Bellido, C.2
Morales, C.3
Reymundo, C.4
Aguilar, E.5
|