A new regulatory principle for in vivo biochemistry: Pleiotropic low affinity regulation by the adenine nucleotides - Illustrated for the glycolytic enzymes of Saccharomyces cerevisiae

FEBS Letters

Volumn 587, Issue 17, 2013, Pages 2860-2867

  Mensonides, Femke I C ^a   Bakker, Barbara M ^b   Cremazy, Frederic ^c   Messiha, Hanan L ^d   Mendes, Pedro ^d,e   Boogerd, Fred C ^a   Westerhoff, Hans V ^a,c,d  

^a VU UNIVERSITY AMSTERDAM   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d UNIVERSITY OF MANCHESTER   (United Kingdom)

^e VIRGINIA BIOINFORMATICS INSTITUTE   (United States)

Author keywords

ATP; Biology; Energetics; Enzyme kinetics; Systems; Yeast glycolysis model

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ADENOSINE DIPHOSPHATE; ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; ALCOHOL; ALCOHOL DEHYDROGENASE; ENOLASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GLUCOSE 6 PHOSPHATE ISOMERASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEXOKINASE; PHOSPHOGLYCERATE KINASE; PHOSPHOGLYCERATE MUTASE; PYRUVATE DECARBOXYLASE; PYRUVATE KINASE; TRIOSEPHOSPHATE ISOMERASE;

ARTICLE; BINDING AFFINITY; BIOCHEMISTRY; CATALYSIS; CHEMICAL PARAMETERS; COMPUTER MODEL; CONTROLLED STUDY; ENERGY TRANSFER; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; ENZYME KINETICS; ENZYME REGULATION; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; FERMENTATION; GLYCOLYSIS; IN VIVO STUDY; MICHAELIS CONSTANT; MOLECULAR INTERACTION; NONHUMAN; PLEIOTROPY; PRIORITY JOURNAL; REGULATORY MECHANISM; SACCHAROMYCES CEREVISIAE; STANDARDIZATION; VMAX;

2-PHOSPHOGLYCERIC ACID; 2PGA; 3-PHOSPHOGLYCERATE KINASE (EC 2.7.2.3); 3-PHOSPHOGLYCERIC ACID; 3PGA; ADH; ALCOHOL DEHYDROGENASE (EC 1.1.1.1); ALD; ATP; ENERGETICS; ENO; ENOLASE (EC 4.2.1.11); ENZYME KINETICS; ETHANOL; ETOH; F16BP; F26BP; F6P; FRUCTOSE 1,6-BISPHOSPHATE; FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE (EC 4.1.2.13); FRUCTOSE 2,6-BISPHOSPHATE; FRUCTOSE 6-PHOSPHATE; G3PDH; G6P; G6PDH; GAP; GAPDH; GLC; GLUCOSE; GLUCOSE 6-PHOSPHATE; GLUCOSE-6-PHOSPHATE DEHYDROGENASE (EC 1.1.1.49); GLYCERALDEHYDE 3-PHOSPHATE; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (EC 1.2.1.12); GLYCEROL 3-PHOSPHATE DEHYDROGENASE (EC 1.1.1.8); HEXOKINASE (EC 2.7.1.1); HXK; LACTATE DEHYDROGENASE (EC 1.1.1.27); LDH; PDC; PEP; PFK; PGI; PGK; PGM; PHOSPHOENOLPYRUVATE; PHOSPHOFRUCTOKINASE (EC 2.7.1.11); PHOSPHOGLUCOSE ISOMERASE (EC 5.3.1.9); PHOSPHOGLYCERATE MUTASE (EC 5.4.2.1); PYK; PYR; PYRUVATE; PYRUVATE DECARBOXYLASE (EC 4.1.1.1); PYRUVATE KINASE (EC 2.7.1.40); SYSTEMS BIOLOGY; TPI; TRIOSEPHOSPHATE ISOMERASE (EC 5.3.1.1); YEAST GLYCOLYSIS MODEL;

ADENINE NUCLEOTIDES; ALLOSTERIC REGULATION; FERMENTATION; GLYCOLYSIS; KINETICS; MODELS, BIOLOGICAL; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SUBCELLULAR FRACTIONS; THERMODYNAMICS;

SACCHAROMYCES CEREVISIAE;

EID: 84883052726     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.07.013     Document Type: Article

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