메뉴 건너뛰기




Volumn 10, Issue 3, 2013, Pages 264-308

An evidence-based systematic review of active hexose correlated compound (AHCC) by the natural standard research collaboration

Author keywords

Active hexose correlated compound; Adverse effects; AHCC; Dosing; Evidence based; Interactions; Pharmacodynamics; Pharmacokinetics; Pharmacology; Systematic review

Indexed keywords


EID: 84883041874     PISSN: 19390211     EISSN: 1939022X     Source Type: Journal    
DOI: 10.3109/19390211.2013.822631     Document Type: Article
Times cited : (10)

References (125)
  • 2
    • 0041627936 scopus 로고    scopus 로고
    • Active hexose correlated compound enhances resistance to Klebsiella pneumoniae infection in mice in the hindlimbunloading model of spaceflight conditions
    • Aviles H, Belay T, Fountain K, Vance M, Sun B, Sonnenfeld G. Active hexose correlated compound enhances resistance to Klebsiella pneumoniae infection in mice in the hindlimbunloading model of spaceflight conditions. J Appl Physiol. 2003;95(2):491-496.
    • (2003) J Appl Physiol , vol.95 , Issue.2 , pp. 491-496
    • Aviles, H.1    Belay, T.2    Fountain, K.3    Vance, M.4    Sun, B.5    Sonnenfeld, G.6
  • 3
    • 4644288955 scopus 로고    scopus 로고
    • Active hexose correlated compound enhances the immune function of mice in the hindlimb-unloading model of spaceflight conditions
    • AvilesH, Belay T, VanceM, Sun B, Sonnenfeld, G.Active hexose correlated compound enhances the immune function of mice in the hindlimb-unloading model of spaceflight conditions. J Appl.Physiol. 2004;97(4):1437-1444.
    • (2004) J Appl.Physiol , vol.97 , Issue.4 , pp. 1437-1444
    • Aviles, H.1    Belay, T.2    Vance, M.3    Sun, B.4    Sonnenfeld, G.5
  • 4
    • 40949143200 scopus 로고    scopus 로고
    • Active hexose correlated compound activates immune function to decrease bacterial load in a murine model of intramuscular infection
    • Aviles H, O'Donnell P, Orshal J, Fujii H, Sun B, Sonnenfeld, G. Active hexose correlated compound activates immune function to decrease bacterial load in a murine model of intramuscular infection. Am J Surg. 2008;195(4):537-545.
    • (2008) Am J Surg , vol.195 , Issue.4 , pp. 537-545
    • Aviles, H.1    O'Donnell, P.2    Orshal, J.3    Fujii, H.4    Sun, B.5    Sonnenfeld, G.6
  • 5
    • 33847408946 scopus 로고    scopus 로고
    • Active hexose correlated compound (AHCC) enhances resistance to infection in a mouse model of surgical wound infection
    • Aviles H, O'Donnell P, Sun B, Sonnenfeld, G. Active hexose correlated compound (AHCC) enhances resistance to infection in a mouse model of surgical wound infection. Surg Infect (Larchmt). 2006;7(6):527-535.
    • (2006) Surg Infect (Larchmt) , vol.7 , Issue.6 , pp. 527-535
    • Aviles, H.1    O'Donnell, P.2    Sun, B.3    Sonnenfeld, G.4
  • 6
    • 84883000064 scopus 로고    scopus 로고
    • Effects of supplementing a combination of nucleoforceR-andAHCC to dairy calves prior weaning on respiratory afflictions and immune response during the postweaning period
    • Presented at the
    • Bach A, Ferrer A, Puig DM, Ahedo J, Chetri, C. Effects of supplementing a combination of nucleoforceR-andAHCC to dairy calves prior weaning on respiratory afflictions and immune response during the postweaning period. Presented at the 18th International Congress on Nutrition and Integrative Medicine (ICNIM) 2010.
    • (2010) 18th International Congress on Nutrition and Integrative Medicine (ICNIM)
    • Bach, A.1    Ferrer, A.2    Puig, D.M.3    Ahedo, J.4    Chetri, C.5
  • 8
    • 84883018598 scopus 로고    scopus 로고
    • Efficacy of active hexose correlated compound (AHCC) in treatment of hepatocellular carcinoma patients at the National Cancer Center of Mongolia
    • Presented at the
    • Bold-Erdene A, Baatamum A, Jigjidsuren, C. Efficacy of active hexose correlated compound (AHCC) in treatment of hepatocellular carcinoma patients at the National Cancer Center of Mongolia. Presented at the 20th InternationalCongress on Nutrition and IntegrativeMedicine (ICNIM) 2012.
    • (2012) 20th InternationalCongress on Nutrition and Integrative Medicine (ICNIM)
    • Bold-Erdene, A.1    Baatamum, A.2    Jigjidsuren, C.3
  • 9
    • 0034494301 scopus 로고    scopus 로고
    • Suppressive effect of active hexose correlated compound (AHCC) on thymic apoptosis induced by dexamethasone in the rat
    • Burikhanov RB, Wakame K, Igarashi Y, Wang S, Matsuzaki, S. Suppressive effect of active hexose correlated compound (AHCC) on thymic apoptosis induced by dexamethasone in the rat. Endocr Regul. 2000;34(4):181-188.
    • (2000) Endocr Regul , vol.34 , Issue.4 , pp. 181-188
    • Burikhanov, R.B.1    Wakame, K.2    Igarashi, Y.3    Wang, S.4    Matsuzaki, S.5
  • 15
    • 84867899925 scopus 로고    scopus 로고
    • The nutritional supplement active hexose correlated compound (AHCC) has direct immunomodulatory actions on intestinal epithelial cells and macrophages involving TLR/MyD88 and NF-kappaB/MAPK activation
    • Daddaoua A, Martinez-Plata E, Ortega-Gonzalez M, Ocon B, Aranda CJ, Zarzuelo A, Suarez MD, de Medina FS, Martinez-Augustin, O. The nutritional supplement active hexose correlated compound (AHCC) has direct immunomodulatory actions on intestinal epithelial cells and macrophages involving TLR/MyD88 and NF-kappaB/MAPK activation. Food Chem. 2013;136(3-4):1288-1295.
    • (2013) Food Chem , vol.136 , Issue.3-4 , pp. 1288-1295
    • Daddaoua, A.1    Martinez-Plata, E.2    Ortega-Gonzalez, M.3    Ocon, B.4    Aranda, C.J.5    Zarzuelo, A.6    Suarez, M.D.7    De Medina, F.S.8    Martinez-Augustin, O.9
  • 19
    • 50249091610 scopus 로고    scopus 로고
    • Nutritional food active hexose correlated xompound (AHCC) enhances resistance against bird flu
    • Fujii H, Nishioka H, Wakame K, Sun, B. Nutritional food active hexose correlated xompound (AHCC) enhances resistance against bird flu. Jpn J Complimentary and Alt Med. 2007;4(2):37-39.
    • (2007) Jpn J Complimentary and Alt Med , vol.4 , Issue.2 , pp. 37-39
    • Fujii, H.1    Nishioka, H.2    Wakame, K.3    Sun, B.4
  • 20
    • 79952070298 scopus 로고    scopus 로고
    • Genotoxicity and subchronic toxicity evaluation of active hexose correlated compound (AHCC)
    • Fujii H, Nishioka N, Simon RR, Kaur R, Lynch B, Roberts, A. Genotoxicity and subchronic toxicity evaluation of active hexose correlated compound (AHCC).Regul Toxicol Pharmacol. 2011;59(2):237-250.
    • (2011) Regul Toxicol Pharmacol , vol.59 , Issue.2 , pp. 237-250
    • Fujii, H.1    Nishioka, N.2    Simon, R.R.3    Kaur, R.4    Lynch, B.5    Roberts, A.6
  • 22
    • 33745728087 scopus 로고    scopus 로고
    • Active hexose correlated compound enhances tumor surveillance through regulating both innate and adaptive immune responses
    • Gao Y, Zhang D, Sun B, Fujii H, Kosuna K, Yin Z. Active hexose correlated compound enhances tumor surveillance through regulating both innate and adaptive immune responses. Cancer Immunol Immunother. 2006;55(10):1258-1266.
    • (2006) Cancer Immunol Immunother , vol.55 , Issue.10 , pp. 1258-1266
    • Gao, Y.1    Zhang, D.2    Sun, B.3    Fujii, H.4    Kosuna, K.5    Yin, Z.6
  • 24
    • 84883007452 scopus 로고    scopus 로고
    • AHCC supplementation of energy-restricted mice may improve natural killer cell function during primary influenza infection
    • Presented at the
    • Gardner E. AHCC supplementation of energy-restricted mice may improve natural killer cell function during primary influenza infection. Presented at the 20th International Congress on Nutrition and Integrative Medicine (ICNIM) 2012.
    • (2012) 20th International Congress on Nutrition and Integrative Medicine (ICNIM)
    • Gardner, E.1
  • 26
    • 84883002510 scopus 로고
    • NK-immunomodulation by active hemicellulose compound (AHCC) in 17 cancer patients
    • Presented at the
    • Ghonewn M. NK-immunomodulation by active hemicellulose compound (AHCC) in 17 cancer patients. Presented at the 2nd Meeting of the Society for Natural Immunity 1994.
    • (1994) 2nd Meeting of the Society for Natural Immunity
    • Ghonewn, M.1
  • 27
    • 84883043670 scopus 로고    scopus 로고
    • Active hexose correlated compound (AHCC) inhibits disruption of endothelial adherens junction induced by high concentration of glucose
    • Presented at the
    • Haidari M, Zhang W, Chen, Z. Active hexose correlated compound (AHCC) inhibits disruption of endothelial adherens junction induced by high concentration of glucose. Presented at the 20th International Congress on Nutrition and Integrative Medicine (ICNIM) 2012.
    • (2012) 20th International Congress on Nutrition and Integrative Medicine (ICNIM)
    • Haidari, M.1    Zhang, W.2    Chen, Z.3
  • 30
  • 32
    • 84883012996 scopus 로고    scopus 로고
    • Evaluation of AHCC for quality of life (QOL) as integrative medicine during treatment of advanced head and neck cancer patients
    • Presented at the
    • Hirata S, Takanari J, Wakame, K. Evaluation of AHCC for quality of life (QOL) as integrative medicine during treatment of advanced head and neck cancer patients. Presented at the 20th International Congress on Nutrition and Integrative Medicine (ICNIM) 2012.
    • (2012) 20th International Congress on Nutrition and Integrative Medicine (ICNIM)
    • Hirata, S.1    Takanari, J.2    Wakame, K.3
  • 34
    • 34447639427 scopus 로고    scopus 로고
    • The influence of active hexose correlated compound (AHCC) on cisplatin-evoked chemotherapeutic and side effects in tumor-bearing mice
    • Hirose A, Sato E, Fujii H, Sun B, Nishioka H, and Aruoma OI. The influence of active hexose correlated compound (AHCC) on cisplatin-evoked chemotherapeutic and side effects in tumor-bearing mice. Toxicol Appl Pharmacol. 2007;222(2):152-158.
    • (2007) Toxicol Appl Pharmacol , vol.222 , Issue.2 , pp. 152-158
    • Hirose, A.1    Sato, E.2    Fujii, H.3    Sun, B.4    Nishioka, H.5    Aruoma, O.I.6
  • 36
    • 33746437109 scopus 로고    scopus 로고
    • The effects of GAC on the biochemical profiles and quality of life of metastatic prostate cancer patients
    • Hong SJ, Chung BH, Kim JS, Lee MJ, Yoon S, Oh HY, Lee EJ, Lim HG, Buxiang, S. The effects of GAC on the biochemical profiles and quality of life of metastatic prostate cancer patients. Korean J Urol. 2006;47(5):467-474.
    • (2006) Korean J Urol , vol.47 , Issue.5 , pp. 467-474
    • Hong, S.J.1    Chung, B.H.2    Kim, J.S.3    Lee, M.J.4    Yoon, S.5    Oh, H.Y.6    Lee, E.J.7    Lim, H.G.8    Buxiang, S.9
  • 37
    • 84863040070 scopus 로고    scopus 로고
    • Evaluation of active hexose correlated compound (AHCC) in combination with pegylated liposomal doxorubicin for treatment of ovarian cancer
    • Hunter RJ, Fujii H, Wakame K, GaikwadA, Wolf JK, Smith JA. Evaluation of active hexose correlated compound (AHCC) in combination with pegylated liposomal doxorubicin for treatment of ovarian cancer. Int J Appl Res Nat Prod. 2011;4(3):6-14.
    • (2011) Int J Appl Res Nat Prod , vol.4 , Issue.3 , pp. 6-14
    • Hunter, R.J.1    Fujii, H.2    Wakame, K.3    Gaikwada Wolf, J.K.4    Smith, J.A.5
  • 39
    • 0038246465 scopus 로고    scopus 로고
    • Prophylactic efficacy of a basidiomycetes preparation AHCC against lethal Candida albicans infection in experimental granulocytopenic mice
    • Ikeda T, Ishibashi H, Fujisaki R, Yamazaki M, Wakame K, Kosuna K, Yamaguchi H, Ono Y, Abe S. [Prophylactic efficacy of a basidiomycetes preparation AHCC against lethal Candida albicans infection in experimental granulocytopenic mice]. Nihon Ishinkin Gakkai Zasshi. 2003;44(2):127-131.
    • (2003) Nihon Ishinkin Gakkai Zasshi , vol.44 , Issue.2 , pp. 127-131
    • Ikeda, T.1    Ishibashi, H.2    Fujisaki, R.3    Yamazaki, M.4    Wakame, K.5    Kosuna, K.6    Yamaguchi, H.7    Ono, Y.8    Abe, S.9
  • 41
    • 84882971419 scopus 로고    scopus 로고
    • Therapeutic gaps between the evidence based medicine (EBM) and cancer patients in the advanced stage or recurrence: Review of cancer therapy with AHCC and GCP under individual EBMfrom the long-term follow-up over 11 years for cancer of the lung and the Brea
    • Presented at the
    • Ishizuka R, FujiiH, Miura T, Fukuchi Y, Tajima K. Therapeutic gaps between the evidence based medicine (EBM) and cancer patients in the advanced stage or recurrence: review of cancer therapy with AHCC and GCP under individual EBMfrom the long-term follow-up over 11 years for cancer of the lung and the Brea. Presented at the 17th International Congress on Nutrition and Integrative Medicine (ICNIM) 2009.
    • (2009) 17th International Congress on Nutrition and Integrative Medicine (ICNIM)
    • Ishizuka, R.1    Fujii, H.2    Miura, T.3    Fukuchi, Y.4    Tajima, K.5
  • 42
    • 84882963296 scopus 로고    scopus 로고
    • Review of cancer therapy with AHCCR-and GCPR-The long-term follow-up over 12 years for stage IV (M1) cancer of the lung and the breast
    • Ishizuka R, Fujii H, Miura T, Fukuchi Y, Tajima K. Review of cancer therapy with AHCCR-and GCPR-; The long-term follow-up over 12 years for stage IV (M1) cancer of the lung and the breast. Int J Integr Med. 2010;2(1):98-111.
    • (2010) Int J Integr Med , vol.2 , Issue.1 , pp. 98-111
    • Ishizuka, R.1    Fujii, H.2    Miura, T.3    Fukuchi, Y.4    Tajima, K.5
  • 46
    • 84882962016 scopus 로고    scopus 로고
    • Effect of AHCC on IFN-al antisense RNA and mRNA expression levels in the respiratory tract of influenza virus AlPR/8/34-infected guinea pigs
    • Presented at the
    • Jiang S, Nakano T, Nishizawa M, Kimura T. Effect of AHCC on IFN-al antisense RNA and mRNA expression levels in the respiratory tract of influenza virus AlPR/8/34-infected guinea pigs. Presented at the 20th International Congress on Nutrition and IntegrativeMedicine (ICNIM) 2012.
    • (2012) 20th International Congress on Nutrition and IntegrativeMedicine (ICNIM)
    • Jiang, S.1    Nakano, T.2    Nishizawa, M.3    Kimura, T.4
  • 48
    • 81855204480 scopus 로고    scopus 로고
    • Improved survival of patients with gastric cancer or colon cancerwhen treated with active hexose correlated compound (AHCC): Effect of AHCCon digestive system cancer
    • KawaguchiY. Improved survival of patients with gastric cancer or colon cancerwhen treated with active hexose correlated compound (AHCC): effect ofAHCCon digestive system cancer. Nat Med J. 2009;1(1):1-6.
    • (2009) Nat Med J , vol.1 , Issue.1 , pp. 1-6
    • Kawaguchi, Y.1
  • 49
    • 0034006918 scopus 로고    scopus 로고
    • The use of mushroom glucans and proteoglycans in cancer treatment
    • Kidd PM. The use of mushroom glucans and proteoglycans in cancer treatment.AlternMed Rev. 2000;5(1):4-27.
    • (2000) Altern Med Rev , vol.5 , Issue.1 , pp. 4-27
    • Kidd, P.M.1
  • 50
    • 84883026819 scopus 로고    scopus 로고
    • The effect of AHCC in non-viral, chronic and abnormal liver function condition: A randomized, double-blind, placebo-control study
    • Presented at the
    • Kim J. The effect of AHCC in non-viral, chronic and abnormal liver function condition: a randomized, double-blind, placebo-control study. Presented at the 18th International Congress on Nutrition and Integrative Medicine (ICNIM) 2010.
    • (2010) 18th International Congress on Nutrition and Integrative Medicine (ICNIM)
    • Kim, J.1
  • 55
    • 84860557616 scopus 로고    scopus 로고
    • Active hexose correlated compound promotes T helper (Th) 17 and 1 cell responses via inducing IL-1beta production from monocytes in humans
    • Lee WW, Lee N, Fujii H, Kang, I. Active hexose correlated compound promotes T helper (Th) 17 and 1 cell responses via inducing IL-1beta production from monocytes in humans. Cell Immunol. 2012;275(1-2):19-23.
    • (2012) Cell Immunol , vol.275 , Issue.1-2 , pp. 19-23
    • Lee, W.W.1    Lee, N.2    Fujii, H.3    Kang, I.4
  • 58
    • 51549105072 scopus 로고    scopus 로고
    • Evaluation of active hexose correlated compound hepatic metabolism and potential for drug interactions with chemotherapy agents
    • Mach CM, Fugii H, Wakame K, Smith J. Evaluation of active hexose correlated compound hepatic metabolism and potential for drug interactions with chemotherapy agents. J Soc Integr Oncol. 2008;6(3):105-109.
    • (2008) J Soc Integr Oncol , vol.6 , Issue.3 , pp. 105-109
    • MacH, C.M.1    Fugii, H.2    Wakame, K.3    Smith, J.4
  • 62
    • 80755129378 scopus 로고    scopus 로고
    • Active hexose correlated compound inhibits the expression of proinflammatory biomarker iNOS in hepatocytes
    • Matsui K, Ozaki T, Oishi M, Tanaka Y, KaiboriM, Nishizawa M, Okumura T, Kwon AH. Active hexose correlated compound inhibits the expression of proinflammatory biomarker iNOS in hepatocytes. Eur Surg Res. 2011;47(4):274-283.
    • (2011) Eur Surg Res , vol.47 , Issue.4 , pp. 274-283
    • Matsui, K.1    Ozaki, T.2    Oishi, M.3    Tanaka, Y.4    Kaibori, M.5    Nishizawa, M.6    Okumura, T.7    Kwon, A.H.8
  • 63
    • 84882969137 scopus 로고    scopus 로고
    • Retrospective study in breast cancer patients supplemented with AHCC
    • Matsui Y, KamiyamaY.Retrospective study in breast cancer patients supplementedwithAHCC. Int J Integr Oncol. 2009;3(2):12-16.
    • (2009) Int J Integr Oncol , vol.3 , Issue.2 , pp. 12-16
    • Matsui, Y.1    Kamiyama, Y.2
  • 65
    • 7144235803 scopus 로고    scopus 로고
    • Combination therapy of active hexose correlated compound plus UFT significantly reduces the metastasis of rat mammary adenocarcinoma
    • Matsushita K, Kuramitsu Y, Ohiro Y, Obara M, Kobayashi M, Li YQ, Hosokawa, M. Combination therapy of active hexose correlated compound plus UFT significantly reduces the metastasis of rat mammary adenocarcinoma. Anticancer Drugs. 1998;9(4):343-350.
    • (1998) Anticancer Drugs , vol.9 , Issue.4 , pp. 343-350
    • Matsushita, K.1    Kuramitsu, Y.2    Ohiro, Y.3    Obara, M.4    Kobayashi, M.5    Li, Y.Q.6    Hosokawa, M.7
  • 73
    • 61749096620 scopus 로고    scopus 로고
    • Low-dose supplementation with active hexose correlated compound improves the immune response to acute influenza infection in C57BL/6 mice
    • Nogusa S, Gerbino J, Ritz BW. Low-dose supplementation with active hexose correlated compound improves the immune response to acute influenza infection in C57BL/6 mice. Nutr Res. 2009;29(2):139-143.
    • (2009) Nutr Res , vol.29 , Issue.2 , pp. 139-143
    • Nogusa, S.1    Gerbino, J.2    Ritz, B.W.3
  • 81
    • 84883031813 scopus 로고    scopus 로고
    • Integrating complimentary and alternative medicine in form of active hexose correlated compound (AHCC) in the management of head & neck cancer patients
    • Parida DK, Wakame K, Nomura T. Integrating complimentary and alternative medicine in form of active hexose correlated compound (AHCC) in the management of head & neck cancer patients. Int J Clin Med. 2011;2:588-592.
    • (2011) Int J Clin Med , vol.2 , pp. 588-592
    • Parida, D.K.1    Wakame, K.2    Nomura, T.3
  • 82
    • 50249136089 scopus 로고    scopus 로고
    • Supplementation with active hexose correlated compound increases survival following infectious challenge in mice
    • Ritz BW. Supplementation with active hexose correlated compound increases survival following infectious challenge in mice. Nutr Rev. 2008;66(9):526-531.
    • (2008) Nutr Rev , vol.66 , Issue.9 , pp. 526-531
    • Ritz, B.W.1
  • 83
    • 33751095144 scopus 로고    scopus 로고
    • Supplementation with active hexose correlated compound increases the innate immune response of young mice to primary influenza infection
    • Ritz BW, Nogusa S, Ackerman EA, Gardner EM. Supplementation with active hexose correlated compound increases the innate immune response of young mice to primary influenza infection. J Nutr. 2006;136(11):2868-2873.
    • (2006) J Nutr , vol.136 , Issue.11 , pp. 2868-2873
    • Ritz, B.W.1    Nogusa, S.2    Ackerman, E.A.3    Gardner, E.M.4
  • 84
    • 84872825424 scopus 로고    scopus 로고
    • Short-term supplementation with active hexose correlated compound improves the antibody response to influenza B vaccine
    • Roman BE, Beli E, Duriancik DM, Gardner EM. Short-term supplementation with active hexose correlated compound improves the antibody response to influenza B vaccine. Nutr Res. 2013;33(1):12-17.
    • (2013) Nutr Res , vol.33 , Issue.1 , pp. 12-17
    • Roman, B.E.1    Beli, E.2    Duriancik, D.M.3    Gardner, E.M.4
  • 91
    • 70349122946 scopus 로고    scopus 로고
    • Alleviating effect of active hexose correlated compound (AHCC) for anticancer drug-induced side effects in non-tumor-bearingmice
    • Shigama K, NakayaA, Wakame K, Nishioka H, Fujii H. Alleviating effect of active hexose correlated compound (AHCC) for anticancer drug-induced side effects in non-tumor-bearingmice. J Exp Ther Oncol. 2009;8(1):43-51.
    • (2009) J Exp Ther Oncol , vol.8 , Issue.1 , pp. 43-51
    • Shigama, K.1    Nakaya, A.2    Wakame, K.3    Nishioka, H.4    Fujii, H.5
  • 94
    • 26944466845 scopus 로고    scopus 로고
    • Use of animal models for space flight physiology studies, with special focus on the immune system
    • Sonnenfeld G. Use of animal models for space flight physiology studies, with special focus on the immune system. Gravit Space Biol Bull. 2005;18(2):31-35.
    • (2005) Gravit Space Biol Bull , vol.18 , Issue.2 , pp. 31-35
    • Sonnenfeld, G.1
  • 96
    • 38549100038 scopus 로고    scopus 로고
    • A Phase i study of the safety of the nutritional supplement, active hexose correlated compound, AHCC, in healthy volunteers
    • Spierings EL, Fujii H, Sun B, Walshe T. A Phase I study of the safety of the nutritional supplement, active hexose correlated compound, AHCC, in healthy volunteers. JNutr. SciVitaminol (Tokyo). 2007;53(6):536-539.
    • (2007) J Nutr. Sci Vitaminol (Tokyo) , vol.53 , Issue.6 , pp. 536-539
    • Spierings, E.L.1    Fujii, H.2    Sun, B.3    Walshe, T.4
  • 97
    • 84882987348 scopus 로고    scopus 로고
    • Our experience in measuring the increased activity of Properdin in patients with cancer after using AHCC for six months
    • Presented at the
    • Sula J. Our experience in measuring the increased activity of Properdin in patients with cancer after using AHCC for six months. Presented at the 19th International Congress on Nutrition and Integrative Medicine (ICNIM) 2011.
    • (2011) 19th International Congress on Nutrition and Integrative Medicine (ICNIM)
    • Sula, J.1
  • 98
    • 77957697733 scopus 로고    scopus 로고
    • Dietary administration of mushroom mycelium extracts in patients with early stage prostate cancers managed expectantly: A phase II study
    • Sumiyoshi Y, Hashine K, Kakehi Y, Yoshimura K, Satou T, Kuruma H, Namiki S, Shinohara N. Dietary administration of mushroom mycelium extracts in patients with early stage prostate cancers managed expectantly: a phase II study. Jpn J Clin Oncol. 2010;40(10):967-972.
    • (2010) Jpn J Clin Oncol , vol.40 , Issue.10 , pp. 967-972
    • Sumiyoshi, Y.1    Hashine, K.2    Kakehi, Y.3    Yoshimura, K.4    Satou, T.5    Kuruma, H.6    Namiki, S.7    Shinohara, N.8
  • 99
    • 50249176546 scopus 로고    scopus 로고
    • Anti-tumor effects of genistein combined polysaccharide (GCP) and active hexose correlated compound (AHCC)
    • Sun B, Mukoda T, Miura T, Fujii H, Yuan L, White R. Anti-tumor effects of genistein combined polysaccharide (GCP) and active hexose correlated compound (AHCC). Transl Biother. 2001;15(3):379-382.
    • (2001) Transl Biother , vol.15 , Issue.3 , pp. 379-382
    • Sun, B.1    Mukoda, T.2    Miura, T.3    Fujii, H.4    Yuan, L.5    White, R.6
  • 100
    • 0030657681 scopus 로고    scopus 로고
    • Preventive effects of AHCC on carbon tetrachloride induced liver injury in mice
    • Sun B, Wakame K, Mukoda T, Toyoshima A, Kanazawa T, Kosuna K. Preventive effects of AHCC on carbon tetrachloride induced liver injury in mice. Nat Med. 1997;51(4):310-315.
    • (1997) Nat Med , vol.51 , Issue.4 , pp. 310-315
    • Sun, B.1    Wakame, K.2    Mukoda, T.3    Toyoshima, A.4    Kanazawa, T.5    Kosuna, K.6
  • 101
    • 70349952445 scopus 로고    scopus 로고
    • The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurineand methotrexate-induced liver injury in rodents
    • Sun B, Wakame K, Sato E, Nishioka H, Aruoma OI, Fujii H. The effect of active hexose correlated compound in modulating cytosine arabinoside-induced hair loss, and 6-mercaptopurineand methotrexate-induced liver injury in rodents. Cancer Epidemiol. 2009;33(3-4):293-299.
    • (2009) Cancer Epidemiol , vol.33 , Issue.3-4 , pp. 293-299
    • Sun, B.1    Wakame, K.2    Sato, E.3    Nishioka, H.4    Aruoma, O.I.5    Fujii, H.6
  • 102
  • 104
    • 84883041603 scopus 로고    scopus 로고
    • AHCC's impact on the immunological system and adverse effects in patients with disseminated neuroendocrine tumors (NETs) treated with radioisotope preparation (90Y-DOTA-TATE)
    • Presented at the
    • Szalus N, Budlewski T. AHCC's impact on the immunological system and adverse effects in patients with disseminated neuroendocrine tumors (NETs) treated with radioisotope preparation (90Y-DOTA-TATE). Presented at the 20th International Congress on Nutrition and Integrative Medicine (ICNIM) 2012.
    • (2012) 20th International Congress on Nutrition and Integrative Medicine (ICNIM)
    • Szalus, N.1    Budlewski, T.2
  • 109
    • 84883037977 scopus 로고    scopus 로고
    • Astudy of the efficacy of active hexose correlated compound (AHCC) in the treatment of chronic hepatitis C patients at Phramongkutklao Hospital
    • Thaiudom S, Piyaniran W, ChutaputthiA.Astudy of the efficacy of active hexose correlated compound (AHCC) in the treatment of chronic hepatitis C patients at Phramongkutklao Hospital. The Med. News (Thailand). 2010;325:13-16.
    • (2010) The Med. News (Thailand) , vol.325 , pp. 13-16
    • Thaiudom, S.1    Piyaniran, W.2    Chutaputthi, A.3
  • 111
    • 61749088903 scopus 로고    scopus 로고
    • Dramatic prostate-specific antigen response with activated hemicellulose compound in metastatic castration-resistant prostate cancer
    • Turner J, Chaudhary U. Dramatic prostate-specific antigen response with activated hemicellulose compound in metastatic castration-resistant prostate cancer. Anticancer Drugs. 2009;20(3):215-216.
    • (2009) Anticancer Drugs , vol.20 , Issue.3 , pp. 215-216
    • Turner, J.1    Chaudhary, U.2
  • 112
    • 0034099086 scopus 로고    scopus 로고
    • Active hexose correlated compound (AHCC) improves immunological parameters and performance status of patients with solid tumors
    • Uno K, Kosuna K, Sun B, Fujii H, Wakame K, Chikumaru S, Hosokawa G, Ueda Y. Active hexose correlated compound (AHCC) improves immunological parameters and performance status of patients with solid tumors. Biotherapy. 2000;14(3):303-309.
    • (2000) Biotherapy , vol.14 , Issue.3 , pp. 303-309
    • Uno, K.1    Kosuna, K.2    Sun, B.3    Fujii, H.4    Wakame, K.5    Chikumaru, S.6    Hosokawa, G.7    Ueda, Y.8
  • 114
    • 0032843046 scopus 로고    scopus 로고
    • Protective effects of active hexose correlated compound (AHCC) on the onset of diabetes induced by Streptozotocin in the rat
    • Wakame K. Protective effects of active hexose correlated compound (AHCC) on the onset of diabetes induced by Streptozotocin in the rat. Biomed Res. 1999;20(3):145-152.
    • (1999) Biomed Res , vol.20 , Issue.3 , pp. 145-152
    • Wakame, K.1
  • 116
    • 0034762672 scopus 로고    scopus 로고
    • Preventive effects of active hexose correlated compound (AHCC) on oxidative stress induced by ferric nitrilotriacetate in the rat
    • Wang S, Ichimura K, Wakame K. Preventive effects of active hexose correlated compound (AHCC) on oxidative stress induced by ferric nitrilotriacetate in the rat. Dokkyo J Med Sci. 2001a;28(2-3):745-752.
    • (2001) Dokkyo J Med Sci , vol.28 , Issue.2-3 , pp. 745-752
    • Wang, S.1    Ichimura, K.2    Wakame, K.3
  • 117
    • 0034749657 scopus 로고    scopus 로고
    • AHCC on immobilization stress in the rat: Beneficial effects of active hexose correlated compound
    • Wang S, Wakame K, Igarashi Y, Kosuna K, Matsuzaki S. AHCC on immobilization stress in the rat: beneficial effects of active hexose correlated compound. Dokkyo J Med Sci. 2001b;28(1):559-565.
    • (2001) Dokkyo J Med Sci , vol.28 , Issue.1 , pp. 559-565
    • Wang, S.1    Wakame, K.2    Igarashi, Y.3    Kosuna, K.4    Matsuzaki, S.5
  • 118
    • 62749160840 scopus 로고    scopus 로고
    • Oral administration of active hexose correlated compound enhances host resistance to West Nile encephalitis in mice
    • Wang S, Welte T, Fang H, Chang GJ, BornWK, O'Brien RL, Sun B, Fujii H, Kosuna K, Wang T. Oral administration of active hexose correlated compound enhances host resistance to West Nile encephalitis in mice. J Nutr. 2009;139(3):598-602.
    • (2009) J Nutr , vol.139 , Issue.3 , pp. 598-602
    • Wang, S.1    Welte, T.2    Fang, H.3    Chang, G.J.4    Born, W.K.5    O'Brien, R.L.6    Sun, B.7    Fujii, H.8    Kosuna, K.9    Wang, T.10
  • 120
    • 0036225057 scopus 로고    scopus 로고
    • H-2 haplotype-dependent serum IL-12 production in tumor-bearing mice treated with various mycelial extracts
    • Yagita A, Maruyama S, Wakasugi S, Sukegawa Y. H-2 haplotype-dependent serum IL-12 production in tumor-bearing mice treated with various mycelial extracts. In Vivo. 2002;16(1):49-54.
    • (2002) In Vivo , vol.16 , Issue.1 , pp. 49-54
    • Yagita, A.1    Maruyama, S.2    Wakasugi, S.3    Sukegawa, Y.4
  • 121
    • 84882937570 scopus 로고    scopus 로고
    • The beneficial effect of active hexose correlated compound (AHCC) a health food component in patients with pancreatic or biliary tract cancer who underwent chemotherapy
    • Presented at the
    • Yanagimoto H, Satoi S, Toyokawa S, Yamamoto T, Hirooka S, Yamao J, Araki H, Matsui Y, Kwon, A. The beneficial effect of active hexose correlated compound (AHCC), a health food component, in patients with pancreatic or biliary tract cancer who underwent chemotherapy. Presented at the 40th APA (American Pancreatic Association) 2009.
    • (2009) 40th APA (American Pancreatic Association)
    • Yanagimoto, H.1    Satoi, S.2    Toyokawa, S.3    Yamamoto, T.4    Hirooka, S.5    Yamao, J.6    Araki, H.7    Matsui, Y.8    Kwon, A.9
  • 122
    • 0242583979 scopus 로고    scopus 로고
    • Suppressive effects of active hexose correlated compound on the increased activity of hepatic and renal ornithine decarboxylase induced by oxidative stress
    • Ye SF, IchimuraK, WakameK, Ohe M. Suppressive effects of active hexose correlated compound on the increased activity of hepatic and renal ornithine decarboxylase induced by oxidative stress. Life Sci. 2003;74(5):593-602.
    • (2003) Life Sci , vol.74 , Issue.5 , pp. 593-602
    • Ye, S.F.1    Wakamek, I.2    Ohe, M.3
  • 123
    • 4043087856 scopus 로고    scopus 로고
    • Amelioration by active hexose correlated compound of endocrine disturbances induced by oxidative stress in the rat
    • Ye SF, Wakame K, Ichimura K, Matsuzaki S. Amelioration by active hexose correlated compound of endocrine disturbances induced by oxidative stress in the rat. Endocr Regul. 2004;38(1):7-13.
    • (2004) Endocr Regul , vol.38 , Issue.1 , pp. 7-13
    • Ye, S.F.1    Wakame, K.2    Ichimura, K.3    Matsuzaki, S.4
  • 124
    • 78149412417 scopus 로고    scopus 로고
    • Effects of active hexose correlated compound on frequency of CD4+ and CD8+ T cells producing interferon-gamma and/or tumor necrosis factor-alpha in healthy adults
    • Yin Z, Fujii H, Walshe T. Effects of active hexose correlated compound on frequency of CD4+ and CD8+ T cells producing interferon-gamma and/or tumor necrosis factor-alpha in healthy adults. Hum Immunol. 2010;71(12):1187-1190.
    • (2010) Hum Immunol , vol.71 , Issue.12 , pp. 1187-1190
    • Yin, Z.1    Fujii, H.2    Walshe, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.