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Volumn 4, Issue 2, 2013, Pages 96-103

Crosstalk between wnt signaling and RNA processing in colorectal cancer

Author keywords

Butyrate; Colon cancer; Polyadenylation; RNA processing; Splicing; Wnt activity

Indexed keywords

BUTYRIC ACID; CYCLOOXYGENASE 2; HISTONE DEACETYLASE INHIBITOR; MESSENGER RNA; PROTEIN C JUN; TCF4 PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 84883041381     PISSN: None     EISSN: 18379664     Source Type: Journal    
DOI: 10.7150/jca.5470     Document Type: Article
Times cited : (25)

References (57)
  • 1
    • 0025458150 scopus 로고
    • Mechanisms and experimental evidence relating dietary fibre and starch to protection against large bowel cancer
    • Bingham S. Mechanisms and experimental evidence relating dietary fibre and starch to protection against large bowel cancer. Proc Nutr Soc. 1990; 49: 153-171.
    • (1990) Proc Nutr Soc. , vol.49 , pp. 153-171
    • Bingham, S.1
  • 2
    • 0026495376 scopus 로고
    • Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats
    • Boffa LC, Lupton JR, Mariani MR, Ceppi M, Newmark HL, Scalmati A, Lipkin M. Modulation of colonic epithelial cell proliferation, histone acetylation, and luminal short chain fatty acids by variation of dietary fiber (wheat bran) in rats. Cancer Res. 1992; 52: 5906-5912.
    • (1992) Cancer Res. , vol.52 , pp. 5906-5912
    • Boffa, L.C.1    Lupton, J.R.2    Mariani, M.R.3    Ceppi, M.4    Newmark, H.L.5    Scalmati, A.6    Lipkin, M.7
  • 3
    • 0028286187 scopus 로고
    • Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines
    • Heerdt BG, Houston MA, Augenlicht LH. Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res. 1994; 54: 3288-3294.
    • (1994) Cancer Res. , vol.54 , pp. 3288-3294
    • Heerdt, B.G.1    Houston, M.A.2    Augenlicht, L.H.3
  • 4
    • 0030796349 scopus 로고    scopus 로고
    • Induction of caspase-3 protease activity and apoptosis by butyrate and another inhibitor of histone deacetylase: dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway
    • Medina V, Young GP, Edmonds B, James R, Appleton S, Zalewski PD. Induction of caspase-3 protease activity and apoptosis by butyrate and another inhibitor of histone deacetylase: dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway. Cancer Res. 1997; 57: 3697-3707.
    • (1997) Cancer Res. , vol.57 , pp. 3697-3707
    • Medina, V.1    Young, G.P.2    Edmonds, B.3    James, R.4    Appleton, S.5    Zalewski, P.D.6
  • 5
    • 0032754225 scopus 로고    scopus 로고
    • Butyrate-induced apoptotic cascade in colonic carcinoma cells: modulation of the beta-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin A but not curcumin
    • Bordonaro M, Mariadason JM, Aslam F, Heerdt BG, Augenlicht LH. Butyrate-induced apoptotic cascade in colonic carcinoma cells: modulation of the beta-catenin-Tcf pathway and concordance with effects of sulindac and trichostatin A but not curcumin. Cell Growth Differ. 1999; 10: 713-720.
    • (1999) Cell Growth Differ. , vol.10 , pp. 713-720
    • Bordonaro, M.1    Mariadason, J.M.2    Aslam, F.3    Heerdt, B.G.4    Augenlicht, L.H.5
  • 6
    • 2442637870 scopus 로고    scopus 로고
    • Linear relationship between WNT activity levels and apoptosis in colorectal carcinoma cells exposed to butyrate
    • Lazarova DL, Bordonaro M, Carbone R, Sartorelli AC. Linear relationship between WNT activity levels and apoptosis in colorectal carcinoma cells exposed to butyrate. Internat J Cancer 2004; 110:523-531.
    • (2004) Internat J Cancer , vol.110 , pp. 523-531
    • Lazarova, D.L.1    Bordonaro, M.2    Carbone, R.3    Sartorelli, A.C.4
  • 7
    • 34247157352 scopus 로고    scopus 로고
    • The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitors
    • Bordonaro M, Lazarova DL, Sartorelli AC. The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitors. Exp Cell Res. 2007; 313:1652-1666.
    • (2007) Exp Cell Res. , vol.313 , pp. 1652-1666
    • Bordonaro, M.1    Lazarova, D.L.2    Sartorelli, A.C.3
  • 9
    • 33751269933 scopus 로고    scopus 로고
    • Modulation of oncogenic transcription and alternative splicing by β-catenin and an RNA aptamer in colon cancer cells
    • Lee HK, Choi YS, Park YA, Jeong S. Modulation of oncogenic transcription and alternative splicing by β-catenin and an RNA aptamer in colon cancer cells. Cancer Res. 2006; 66: 10560-10566.
    • (2006) Cancer Res. , vol.66 , pp. 10560-10566
    • Lee, H.K.1    Choi, Y.S.2    Park, Y.A.3    Jeong, S.4
  • 10
    • 35148861084 scopus 로고    scopus 로고
    • Beta-catenin regulates multiple steps of RNA metabolism as revealed by the RNA aptamer in colon cancer cells
    • Lee HK, Kwak HY, Hur J, Kim IA., Yang JS, Park MW, Yu J, Jeong S. Beta-catenin regulates multiple steps of RNA metabolism as revealed by the RNA aptamer in colon cancer cells. Cancer Res.2007; 67: 93150-9321.
    • (2007) Cancer Res. , vol.67 , pp. 93150-9321
    • Lee, H.K.1    Kwak, H.Y.2    Hur, J.3    Kim, I.A.4    Yang, J.S.5    Park, M.W.6    Yu, J.7    Jeong, S.8
  • 11
    • 0029002337 scopus 로고
    • Sodium butyrate inhibits c-myc splicing and interferes with signal transduction in ovarian carcinoma cells
    • Krupitza G, Harant H, Dittrich E, Szekeres T, Huber H, Dittrich C. Sodium butyrate inhibits c-myc splicing and interferes with signal transduction in ovarian carcinoma cells. Carcinogenesis 1995; 16: 1199-1205.
    • (1995) Carcinogenesis , vol.16 , pp. 1199-1205
    • Krupitza, G.1    Harant, H.2    Dittrich, E.3    Szekeres, T.4    Huber, H.5    Dittrich, C.6
  • 13
    • 0023932454 scopus 로고
    • Transcriptional and posttranscriptional modulation of calcitonin gene expression by sodium n-butyrate in cultured human medullary thyroid carcinoma
    • Nakagawa T, Nelkin BD, Baylin SB, de Bustros A. Transcriptional and posttranscriptional modulation of calcitonin gene expression by sodium n-butyrate in cultured human medullary thyroid carcinoma. Cancer Res. 1988; 48: 2096-2100.
    • (1988) Cancer Res. , vol.48 , pp. 2096-2100
    • Nakagawa, T.1    Nelkin, B.D.2    Baylin, S.B.3    de Bustros, A.4
  • 14
    • 84867479500 scopus 로고    scopus 로고
    • Protein cross-talk in CD133+ colon cancer cells indicates activation of the Wnt pathway and up-regulation of SRp20 that is potentially involved in tumorigenicity
    • Corbo C, Orru S, Gemei M, Noto RD, Mirabelli P, Imperlini E, Ruoppolo M, Vecchio LD, Salvatore F. Protein cross-talk in CD133+ colon cancer cells indicates activation of the Wnt pathway and up-regulation of SRp20 that is potentially involved in tumorigenicity. Proteomics 2012; 12: 2045-2059.
    • (2012) Proteomics , vol.12 , pp. 2045-2059
    • Corbo, C.1    Orru, S.2    Gemei, M.3    Noto, R.D.4    Mirabelli, P.5    Imperlini, E.6    Ruoppolo, M.7    Vecchio, L.D.8    Salvatore, F.9
  • 15
    • 17144470484 scopus 로고    scopus 로고
    • A double reporter assay for detecting changes in the ratio of spliced and unspliced mRNA in mammalian cells
    • Nasim MT, Chowdhury HM, Eperon IC. A double reporter assay for detecting changes in the ratio of spliced and unspliced mRNA in mammalian cells. Nucl Acids Res. 2002; 30: e109.
    • (2002) Nucl Acids Res. , vol.30
    • Nasim, M.T.1    Chowdhury, H.M.2    Eperon, I.C.3
  • 18
    • 34547233180 scopus 로고    scopus 로고
    • Systems perspectives on mRNA processing
    • McKee AE, Silver PA. Systems perspectives on mRNA processing. Cell Res. 2007; 17: 581-590.
    • (2007) Cell Res. , vol.17 , pp. 581-590
    • McKee, A.E.1    Silver, P.A.2
  • 19
    • 68949158449 scopus 로고    scopus 로고
    • A novel SULF1 splice variant inhibits Wnt signaling but enhances angiogenesis opposing SULF1 activity
    • Sahota AP, Dhoot GK. A novel SULF1 splice variant inhibits Wnt signaling but enhances angiogenesis opposing SULF1 activity. Expt Cell Res. 2009; 315:2752-2764.
    • (2009) Expt Cell Res. , vol.315 , pp. 2752-2764
    • Sahota, A.P.1    Dhoot, G.K.2
  • 20
    • 77955663252 scopus 로고    scopus 로고
    • Characterization of a novel human CDK5 splicing variant that inhibits Wnt/beta-catenin signaling
    • Li Q, Liu X., Zhang M, Ye G, Qiao Q, Ling Y, Wu Y, Zhang Y, Yu L. Characterization of a novel human CDK5 splicing variant that inhibits Wnt/beta-catenin signaling. Mol Biol Rep. 2010; 37: 2415-2421.
    • (2010) Mol Biol Rep. , vol.37 , pp. 2415-2421
    • Li, Q.1    Liu, X.2    Zhang, M.3    Ye, G.4    Qiao, Q.5    Ling, Y.6    Wu, Y.7    Zhang, Y.8    Yu, L.9
  • 21
    • 77950524963 scopus 로고    scopus 로고
    • Aberrant splicing of the E-cadherin transcript is a novel mechanism of gene silencing in chronic lymphocytic leukemia cells
    • Sharma S, Lichtenstein A. Aberrant splicing of the E-cadherin transcript is a novel mechanism of gene silencing in chronic lymphocytic leukemia cells. Blood 2009; 114: 4179-4185.
    • (2009) Blood , vol.114 , pp. 4179-4185
    • Sharma, S.1    Lichtenstein, A.2
  • 22
    • 70350782482 scopus 로고    scopus 로고
    • Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways
    • Goncalves V, Matos P, Jordan P. Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways. Hum Mol Genet. 2009; 18: 3696-3707.
    • (2009) Hum Mol Genet. , vol.18 , pp. 3696-3707
    • Goncalves, V.1    Matos, P.2    Jordan, P.3
  • 24
    • 34948822375 scopus 로고    scopus 로고
    • Suppression of nuclear Wnt signaling leads to stabilization of Rac1 isoforms
    • Esufali S, Charames GS, Bapat B. Suppression of nuclear Wnt signaling leads to stabilization of Rac1 isoforms. FEBS Lett. 2007; 581: 4850-4856.
    • (2007) FEBS Lett. , vol.581 , pp. 4850-4856
    • Esufali, S.1    Charames, G.S.2    Bapat, B.3
  • 25
    • 34047269793 scopus 로고    scopus 로고
    • Activation of tumor-specific splice variant Rac1b by disheveled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells
    • Esufali S, Charames GS, Pethe VV, Buongiorno P, Bapat B. Activation of tumor-specific splice variant Rac1b by disheveled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells. Cancer Res. 2007; 67: 2469-2479.
    • (2007) Cancer Res. , vol.67 , pp. 2469-2479
    • Esufali, S.1    Charames, G.S.2    Pethe, V.V.3    Buongiorno, P.4    Bapat, B.5
  • 26
  • 29
    • 68349146848 scopus 로고    scopus 로고
    • Human intronless disease genes are slowly evolving
    • Agarwal SM, Srivistava PK. Human intronless disease genes are slowly evolving. BMB Reports 2009; 42: 356-360.
    • (2009) BMB Reports , vol.42 , pp. 356-360
    • Agarwal, S.M.1    Srivistava, P.K.2
  • 30
    • 27144453708 scopus 로고    scopus 로고
    • Evolutionary rate variation in eukaryotic lineage specific human intronless proteins
    • Agarwal SM. Evolutionary rate variation in eukaryotic lineage specific human intronless proteins. Biochem Biophys Res Commun. 2005; 337: 1192-1197.
    • (2005) Biochem Biophys Res Commun. , vol.337 , pp. 1192-1197
    • Agarwal, S.M.1
  • 31
    • 18044392940 scopus 로고    scopus 로고
    • Comparative analysis of human intronless proteins
    • Agarwal SM, Gupta J. Comparative analysis of human intronless proteins. Biochem Biophys Tes Commun. 2005; 331: 512-519.
    • (2005) Biochem Biophys Tes Commun. , vol.331 , pp. 512-519
    • Agarwal, S.M.1    Gupta, J.2
  • 32
    • 3543106033 scopus 로고    scopus 로고
    • Genome-wide identification of genes likely to be involved in human genetic disease
    • Lopez-Bigas N, Ouzounis CA. Genome-wide identification of genes likely to be involved in human genetic disease. Nucl Acids Res. 2004; 32: 3108-3114.
    • (2004) Nucl Acids Res. , vol.32 , pp. 3108-3114
    • Lopez-Bigas, N.1    Ouzounis, C.A.2
  • 33
    • 33746698983 scopus 로고    scopus 로고
    • The non-random distribution of intronless genes across molecular function categories
    • Hill AE, Sorscher EJ. The non-random distribution of intronless genes across molecular function categories. FEBS Lett. 2006; 580:4303-4305.
    • (2006) FEBS Lett. , vol.580 , pp. 4303-4305
    • Hill, A.E.1    Sorscher, E.J.2
  • 35
    • 0023572209 scopus 로고
    • Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1
    • Bohmann D, Bos TJ, Admon A, Nishimura T, Vogt PK, Tjian R. Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science 1987; 238: 1386-1392.
    • (1987) Science , vol.238 , pp. 1386-1392
    • Bohmann, D.1    Bos, T.J.2    Admon, A.3    Nishimura, T.4    Vogt, P.K.5    Tjian, R.6
  • 36
    • 0029828191 scopus 로고    scopus 로고
    • Jun: transcription factor and oncoprotein
    • Rahmsdorf HJ. Jun: transcription factor and oncoprotein. J Mol Med. 1996; 74: 725-747.
    • (1996) J Mol Med. , vol.74 , pp. 725-747
    • Rahmsdorf, H.J.1
  • 38
    • 0742306756 scopus 로고    scopus 로고
    • Dominant-negative mutant of c-jun gene transfer: a novel therapeutic strategy for colorectal cancer
    • Suto R, Tominaga K, Mizuguchi H, Sasaki E, Higuchi K, Kim S, Iwao H, Arakawa T. Dominant-negative mutant of c-jun gene transfer: a novel therapeutic strategy for colorectal cancer. Gene Ther. 2004; 11: 187-193.
    • (2004) Gene Ther. , vol.11 , pp. 187-193
    • Suto, R.1    Tominaga, K.2    Mizuguchi, H.3    Sasaki, E.4    Higuchi, K.5    Kim, S.6    Iwao, H.7    Arakawa, T.8
  • 40
    • 57349146621 scopus 로고    scopus 로고
    • A genome-wide screen for beta- catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression
    • Yochum GS, Cleland R, Goodman RH. A genome-wide screen for beta- catenin binding sites identifies a downstream enhancer element that controls c-Myc gene expression. Mol Cell Biol. 2008; 28: 7368-7379.
    • (2008) Mol Cell Biol. , vol.28 , pp. 7368-7379
    • Yochum, G.S.1    Cleland, R.2    Goodman, R.H.3
  • 42
    • 17644375511 scopus 로고    scopus 로고
    • Pre-mRNA processing enhancer (PPE) elements from intronless genes play additional roles in mRNA biogenesis than do ones from intron-containing genes
    • Guang S, Mertz JE. Pre-mRNA processing enhancer (PPE) elements from intronless genes play additional roles in mRNA biogenesis than do ones from intron-containing genes. Nucl Acids Res. 2005; 33: 2215-2226.
    • (2005) Nucl Acids Res. , vol.33 , pp. 2215-2226
    • Guang, S.1    Mertz, J.E.2
  • 43
    • 0025353565 scopus 로고
    • Unusual c-fos induction upon chromaffin PC12 differentiation by sodium butyrate: loss of fos autoregulatory function
    • Narjano JR, Mellstrom B, Auwerx J, Mollinedo F, Sassone-Corsi P. Unusual c-fos induction upon chromaffin PC12 differentiation by sodium butyrate: loss of fos autoregulatory function. Nucl Acids Res. 1990; 18: 3605-3610.
    • (1990) Nucl Acids Res. , vol.18 , pp. 3605-3610
    • Narjano, J.R.1    Mellstrom, B.2    Auwerx, J.3    Mollinedo, F.4    Sassone-Corsi, P.5
  • 44
    • 0029817201 scopus 로고    scopus 로고
    • In vivo crypt surface hyperproliferation is decreased by butyrate and increased by deoxycholate in normal rat colon: associated in vivo effects on c-fos and c-jun expression
    • Velasquez OC, Zhou D, Seto RW, Jabbar A, Choi J, Lederer HM, Rombeau JL. In vivo crypt surface hyperproliferation is decreased by butyrate and increased by deoxycholate in normal rat colon: associated in vivo effects on c-fos and c-jun expression. J Parent Ent Nutr. 1996; 20: 4243-4250.
    • (1996) J Parent Ent Nutr. , vol.20 , pp. 4243-4250
    • Velasquez, O.C.1    Zhou, D.2    Seto, R.W.3    Jabbar, A.4    Choi, J.5    Lederer, H.M.6    Rombeau, J.L.7
  • 45
    • 0027316830 scopus 로고
    • Rapid alteration of c-myc and c-jun expression in leukemic cells induced to differentiate by a butyric acid prodrug
    • Rabizadeh E, Shaklai M, Nudelman A, Eisenbach L, Rephaeli A. Rapid alteration of c-myc and c-jun expression in leukemic cells induced to differentiate by a butyric acid prodrug. FEBS Lett. 1993; 328: 225-229.
    • (1993) FEBS Lett. , vol.328 , pp. 225-229
    • Rabizadeh, E.1    Shaklai, M.2    Nudelman, A.3    Eisenbach, L.4    Rephaeli, A.5
  • 46
  • 47
    • 68749113985 scopus 로고    scopus 로고
    • Widespread shortening of 3' UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells
    • Mayr C, Bartel DP. Widespread shortening of 3' UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell 2009; 138:673-684.
    • (2009) Cell , vol.138 , pp. 673-684
    • Mayr, C.1    Bartel, D.P.2
  • 48
    • 0028844578 scopus 로고
    • Polymorphism in the N-acetyltransferase 1 (NAT1) polyadenylation signal: association of NAT1*10 allele with higher N-acetylation activity in bladder and colon tissue
    • Bell DA, Badawi AF, Lang NP, Ilett KF, Kadlubar FF, Hirvonen A. Polymorphism in the N-acetyltransferase 1 (NAT1) polyadenylation signal: association of NAT1*10 allele with higher N-acetylation activity in bladder and colon tissue. Cancer Res. 1995; 55: 5226-5229.
    • (1995) Cancer Res. , vol.55 , pp. 5226-5229
    • Bell, D.A.1    Badawi, A.F.2    Lang, N.P.3    Ilett, K.F.4    Kadlubar, F.F.5    Hirvonen, A.6
  • 50
    • 82455212279 scopus 로고    scopus 로고
    • An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid enhancer factor (TCF/LEF)-dependent target genes
    • Locke JM, Da Silva Xavier G, Rutter GA, Harries LW. An alternative polyadenylation signal in TCF7L2 generates isoforms that inhibit T cell factor/lymphoid enhancer factor (TCF/LEF)-dependent target genes. Diabetologia 2011; 54: 3078-3082.
    • (2011) Diabetologia , vol.54 , pp. 3078-3082
    • Locke, J.M.1    Da Silva Xavier, G.2    Rutter, G.A.3    Harries, L.W.4
  • 51
    • 33750993498 scopus 로고    scopus 로고
    • β-catenin stabilizes cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3' UTR
    • Lee HK., Jeong S. β-catenin stabilizes cyclooxygenase-2 mRNA by interacting with AU-rich elements of 3' UTR. Nucl Acids Res. 2006; 34: 5705-5714.
    • (2006) Nucl Acids Res. , vol.34 , pp. 5705-5714
    • Lee, H.K.1    Jeong, S.2
  • 53
    • 77954580056 scopus 로고    scopus 로고
    • The global dynamics of RNA stability orchestrates responses to cellular activation
    • Keene JD. The global dynamics of RNA stability orchestrates responses to cellular activation. BMC Biol. 2010; 8:95.
    • (2010) BMC Biol. , vol.8 , pp. 95
    • Keene, J.D.1
  • 54
    • 77950295790 scopus 로고    scopus 로고
    • Minireview: global regulation and dynamics of ribonucleic acid
    • Keene JD. Minireview: global regulation and dynamics of ribonucleic acid. Endocrinology 2010; 151: 1391-1397.
    • (2010) Endocrinology , vol.151 , pp. 1391-1397
    • Keene, J.D.1
  • 57
    • 84864959539 scopus 로고    scopus 로고
    • β-catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3'-UTR and interacts with HuR in colon cancer cells
    • Kim I, Kwak H, Lee HK, Hyun S, Jeong S. β-catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3'-UTR and interacts with HuR in colon cancer cells. Nucl Acids Res. 2012; 40: 6863-6872.
    • (2012) Nucl Acids Res. , vol.40 , pp. 6863-6872
    • Kim, I.1    Kwak, H.2    Lee, H.K.3    Hyun, S.4    Jeong, S.5


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