X-linked Inhibitor of Apoptosis Protein negatively regulates neuronal differentiation through interaction with cRAF and Trk

Scientific Reports

Volumn 3, Issue , 2013, Pages

  Fadó, Rut ^a,c   Moubarak, Rana S ^b,c   Miñano Molina, Alfredo J ^a,c   Barneda Zahonero, Bruna ^a,c   Valero, Jorge ^a,c   Saura, Carlos A ^a,c   Moran, Julio ^d   Comella, Joan X ^b,c   Rodríguez Álvarez, José ^a,c  

^a INSTITUT DE NEUROCIÈNCIES   (Spain)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

^d UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TYROSINE KINASE A; RAF PROTEIN; X LINKED INHIBITOR OF APOPTOSIS; PROTEIN BINDING;

ANIMAL; ARTICLE; CELL DIFFERENTIATION; CYTOLOGY; GENE EXPRESSION REGULATION; METABOLISM; NERVE CELL; PHYSIOLOGY; PROTEIN BINDING; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MAP KINASE SIGNALING SYSTEM; NEURONS; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-RAF; RATS; RECEPTOR, TRKA; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 84883029053     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep02397     Document Type: Article

References (37)

1. Hinds, M. G., Norton, R. S., Vaux, D. L. & Day, C. L. Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat. Nat Struct Mol Biol 6, 648-651 (1999). (Pubitemid 29318954)
2. Deveraux, Q. L., Takahashi, R., Salvesen, G. S.&Reed, J. C. X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388, 300-304 (1997). (Pubitemid 27317977)
3. Srinivasula, S. M. & Ashwell, J. D. IAPs:What's in a Name? Mol Cell 30, 123-135 (2008).
4. Dubrez-Daloz, L., Dupoux, A. & Cartier, J. IAPS: More than just inhibitors of apoptosis proteins. Cell Cycle 7, 1036-1046 (2008).
5. Varfolomeev, E. et al. c-IAP1 and c-IAP2 Are Critical Mediators of Tumor Necrosis Factora (TNFa)-induced NF-kB Activation. J Biol Chem 283, 24295-24299 (2008).
6. Mace, P. D., Shirley, S. & Day, C. L. Assembling the building blocks: structure and function of inhibitor of apoptosis proteins. Cell Death Differ 17, 46-53 (2009).
7. Riedl, S. J. et al. Structural Basis for the Inhibition of Caspase-3 by XIAP. Cell 104, 791-800 (2001). (Pubitemid 32241028)
8. Chai, J. et al. Structural Basis of Caspase-7 Inhibition by XIAP. Cell 104, 769-780 (2001). (Pubitemid 32241026)
9. Shiozaki, E. N. et al. Mechanism of XIAP-Mediated Inhibition of Caspase-9. Mol Cell 11, 519-527 (2003). (Pubitemid 36293842)
10. Shin, H. et al. Identification of ubiquitination sites on the X-linked inhibitor of apoptosis protein. Biochem. J. 373, 965-971 (2003). (Pubitemid 36981108)
11. Suzuki, Y.,Nakabayashi, Y. & Takahashi, R. Ubiquitin-protein ligase activity of Xlinked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death. Proc Nat Acad Sci 98, 8662-8667 (2001). (Pubitemid 32678084)
12. Morizane, Y., Honda, R., Fukami, K. & Yasuda, H. X-Linked Inhibitor of Apoptosis Functions as Ubiquitin Ligase toward Mature Caspase-9 and Cytosolic Smac/DIABLO. J Biochem 137, 125-132 (2005).
13. Singh, J. & Kaur, G. Neuroprotection mediated by subtoxic dose ofNMDA in SHSY5Y neuroblastoma cultures: Activity-dependent regulation of PSA-NCAM expression. Mol Brain Res 137, 223-234 (2005). (Pubitemid 40798905)
14. Winsauer, G., Resch,U., Hofer-Warbinek, R., Schichl, Y. M. & deMartin, R. XIAP regulates bi-phasic NF-kB induction involving physical interaction and ubiquitination of MEKK2. Cellular Signalling 20, 2107-2112 (2008).
15. Sobrado, M. et al. Synthesis of Lipoxin A4 by 5-Lipoxygenase Mediates PPAR{gamma}-Dependent, Neuroprotective Effects of Rosiglitazone in Experimental Stroke. J Neurosci 29, 3875-3884 (2009).
16. Dogan, T. et al. X-linked and cellular IAPs modulate the stability of C-RAF kinase and cell motility. Nat Cell Biol 10, 1447-1455 (2008).
17. Yamaguchi, K. et al. XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. EMBO J.18, 179-187 (1999). (Pubitemid 29005034)
18. Gruslin, A., Qiu, Q. & Tsang, B. K. X-Linked Inhibitor of Apoptosis Protein Expression and the Regulation of Apoptosis During Human Placental Development. Biol Reproduction 64, 1264-1272 (2001). (Pubitemid 32239199)
19. Olayioye, M. A. et al. XIAP-deficiency leads to delayed lobuloalveolar development in the mammary gland. Cell Death Differ 12, 87-90 (2004).
20. Barnes, A. P. & Polleux, F. Establishment of Axon-Dendrite Polarity in Developing Neurons. Ann Rev Neurosci 32, 347-381 (2009).
21. Liang, Y., Mirnics, Z. K., Yan, C., Nylander, K. D. & Schor, N. F. Bcl-2 mediates induction of neural differentiation. Oncogene 22, 5515-5518 (2003). (Pubitemid 37072206)
22. Sole, C. et al. The death receptor antagonist FAIM promotes neurite outgrowth by amechanism that depends on ERK and NF-kB signaling. J.Cell Biol 167, 479-492 (2004). (Pubitemid 39489056)
23. Moubarak, R. S. et al. The Death Receptor Antagonist FLIP-L Interacts with Trk and Is Necessary for Neurite Outgrowth Induced by Neurotrophins. JNeurosci 30, 6094-6105 (2010).
24. Traverse, S., Gomez, N., Paterson, H., Marshall, C. & Cohen, P. Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor. Biochem J 288, 351-355 (1992).
25. Vaudry, D. et al. PACAP protects cerebellar granule neurons against oxidative stress-induced apoptosis. Eur J Neurosci 15, 1451-1460 (2002). (Pubitemid 35477975)
26. Xing, J., Ginty, D. D. & Greenberg, M. E. Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase. Science 273, 959-963 (1996). (Pubitemid 26275173)
27. Wixler, V., Smola, U., Schuler, M. & Rapp, U. Differential regulation of Raf isozymes by growth versus differentiation inducing factors in PC12 pheochromocytoma cells. FEBS Lett 385, 131-137 (1996). (Pubitemid 26167448)
28. Chao, M. V. & Hempstead, B. L. p75 and Trk: A two-receptor system. Trends Neurosci 18, 321-326 (1995).
29. Galvan, V., Kurakin, A. V. & Bredesen, D. E. Interaction of checkpoint kinase 1 and the X-linked inhibitor of apoptosis during mitosis. FEBS Letters 558, 57-62 (2004). (Pubitemid 38167410)
30. Zhang, Y. et al. Transfer of siRNA against XIAP induces apoptosis and reduces tumor cells growth potential in human breast cancer "in vitro" and "in vivo". Breast Cancer Res Treat 96, 267-277 (2006).
31. Heiman, M. G. & Shaham, S. Twigs into branches: how a filopodium becomes a dendrite. Curr Opinion Neurobiol 20, 86-91 (2010).
32. Hurley, J. H. L. S. & Prag, G. Ubiquitin-binding domains. Biochem J 399, 12 (2006).
33. Sanchez-Ponce, D., Tapia, M., Mun?oz, A. & Garrido, J. J. New role of IKKa/ bphosphorylated IkBain axon outgrowth and axon initial segment development. Mol Cell Neurosci 37, 832-844 (2008).
34. Liu, J. et al. X-linked Inhibitor of Apoptosis Protein (XIAP) Mediates Cancer Cell Motility via Rho GDP Dissociation Inhibitor (RhoGDI)-dependent Regulation of the Cytoskeleton. J Biol Chem 286, 15630-15640 (2011).
35. Malagelada, C., Xifro, X., Minano, A., Sabria, J. & Rodriguez-Alvarez, J. Contribution of caspase-mediated apoptosis to the cell death caused by oxygenglucose deprivation in cortical cell cultures. Neurobiol.Dis. 20, 27-37 (2005). (Pubitemid 41219200)
36. Holcik, M., Lefebvre, C., Yeh, C., Chow, T. & Korneluk, R. G. A new internalribosome- entry-site motif potentiates XIAP- mediated cytoprotection. Nat Cell Biol 1, 190-192 (1999). (Pubitemid 129656025)
37. Naldini, L. et al. In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector. Science 272, 263-267 (1996). (Pubitemid 26119138)