Impact of IGF-I release kinetics on bone healing: A preliminary study in sheep

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 85, Issue 1, 2013, Pages 99-106

  Luginbuehl, Vera ^a,b   Zoidis, Evangelos ^c   Meinel, Lorenz ^a,e   Von Rechenberg, Brigitte ^d   Gander, Bruno ^a   Merkle, Hans P ^a  

^a ETH ZURICH   (Switzerland)

^b ZURICH UNIVERSITY OF APPLIED SCIENCES   (Switzerland)

^c AGRICULTURAL UNIVERSITY OF ATHENS   (Greece)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

Bone healing; Gene expression; Insulin like growth factor I (IGF I); Osteoinduction; PLGA microspheres; Release kinetics

Indexed keywords

RECOMBINANT SOMATOMEDIN B;

ANIMAL CELL; ARTICLE; BONE DEFECT; DOWN REGULATION; ENCAPSULATION; FRACTURE HEALING; HUMAN; HUMAN CELL; IN VITRO STUDY; KINETICS; MARKER GENE; MOUSE; NONHUMAN; OSSIFICATION;

BONE HEALING; GENE EXPRESSION; INSULIN-LIKE GROWTH FACTOR I (IGF-I); OSTEOINDUCTION; PLGA MICROSPHERES; RELEASE KINETICS;

ANIMALS; BONE AND BONES; BONE REGENERATION; CELL LINE, TUMOR; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG IMPLANTS; GENE EXPRESSION REGULATION; GROWTH SUBSTANCES; HUMANS; INFLAMMATION MEDIATORS; INSULIN-LIKE GROWTH FACTOR I; KINETICS; LACTIC ACID; MICROSPHERES; OSTEOGENESIS; POLYESTERS; POLYGLYCOLIC ACID; RANDOM ALLOCATION; RECOMBINANT PROTEINS; SHEEP, DOMESTIC; SOLUBILITY; WOUND HEALING;

EID: 84882997945     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2013.03.004     Document Type: Article

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