Hip2 ubiquitin-conjugating enzyme overcomes radiation-induced G2/M arrest

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1833, Issue 12, 2013, Pages 2911-2921

  Bae, Yoonhee ^a   Jung, Song Hwa ^a   Kim, Goo Young ^b   Rhim, Hyangshuk ^b   Kang, Seongman ^a  

^a Korea University   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

G2 M arrest; Hip2; P53; Radiation; Ubiquitination

Indexed keywords

CYCLIN B1; PROTEIN P53; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN CONJUGATING ENZYME HIP2; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL STRAIN HEK293; CONTROLLED STUDY; FLOW CYTOMETRY; G2 PHASE CELL CYCLE CHECKPOINT; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IONIZING RADIATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RADIATION INJURY; UBIQUITINATION; WESTERN BLOTTING;

EID: 84882979098     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2013.07.023     Document Type: Article

References (25)

1. Walworth N.C. Cell-cycle checkpoint kinases: checking in on the cell cycle. Curr. Opin. Cell Biol. 2000, 12:697-704.
2. Nurse P. Universal control mechanism regulating onset of M-phase. Nature 1990, 344:503-508.
3. Houtgraaf J.H., Versmissen J., van der Giessen W.J. A concise review of DNA damage checkpoints and repair in mammalian cells. Cardiovasc. Revasc. Med. 2006, 7:165-172.
4. Clarke P.R., Allan L.A. Cell-cycle control in the face of damage - a matter of life or death. Trends Cell Biol. 2009, 19:89-98.
5. Maki C.G., Howley P.M. Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation. Mol. Cell. Biol. 1997, 17:355-363.
6. Kruse J.P., Gu W. Modes of p53 regulation. Cell 2009, 137:609-622.
7. Taylor W.R., Stark G.R. Regulation of the G2/M transition by p53. Oncogene 2001, 20:1803-1815.
8. Park M., Chae H.D., Yun J., Jung M., Kim Y.S., Kim S.H., Han M.H., Shin D.Y. Constitutive activation of cyclin B1-associated cdc2 kinase overrides p53-mediated G2-M arrest. Cancer Res. 2001, 60:542-545.
9. Kalchman M.A., Graham R.K., Xia G., Koide H.B., Hodgson J.G., Graham K.C., Goldberg Y.P., Gietz R.D., Pickart C.M., Hayden M.R. Huntingtin is ubiquitinated and interacts with a specific ubiquitin-conjugating enzyme. J. Biol. Chem. 1996, 271:19385-19394.
10. Song S., Kim S.Y., Hong Y.M., Jo D.G., Lee J.Y., Shim S.M., Chung C.W., Seo S.J., Yoo Y.J., Koh J.Y., Lee M.C., Yates A.J., Ichijo H., Jung Y.K. Essential role of E2-25K/Hip-2 in mediating amyloid-beta neurotoxicity. Mol. Cell 2003, 12:553-563.
11. Bae Y., Kho C.W., Lee S.Y., Rhim H., Kang S. Hip2 interacts with and destabilizes Smac/DIABLO. Biochem. Biophys. Res. Commun. 2010, 397:718-723.
12. Bae Y., Choi D., Rhim H., Kang S. Hip2 interacts with cyclin B1 and promotes its degradation through the ubiquitin proteasome pathway. FEBS Lett. 2010, 584:4505-4510.
13. Lee S.J., Choi J.Y., Sung Y.M., Park H., Rhim H., Kang S. E3 ligase activity of RING finger proteins that interact with Hip-2, a human ubiquitin-conjugating enzyme. FEBS Lett. 2001, 503:61-64.
14. Rodrigo-Brenni M.C., Morgan D.O. Sequential E2s drive polyubiquitin chain assembly on APC targets. Cell 2007, 2007(130):127-139.
15. Mastrandrea L.D., Kasperek E.M., Niles E.G., Pickart C.M. Core domain mutation (S86Y) selectively inactivates polyubiquitin chain synthesis catalyzed by E2-25K. Biochemistry 1998, 37:9784-9792.
16. Eriksson D., Löfroth P.O., Johansson L., Riklund k.A., Stigbrand T. Cell cycle disturbances and mitotic catastrophes in HeLa Hep2 cells following 2.5 to 10Gy of ionizing radiation. Clin. Cancer Res. 2007, 13:5501s-5508s.
17. Yang X.M., Wood P.A., Hrushesky W.J.M. Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G(2)/M checkpoint control. J. Biol. Chem. 2010, 285.
18. Junttila M.R., Evan G.I. p53-a Jack of all trades but master of none. Nat. Rev. Cancer 2009, 9:821-829.
19. Fei P., El-Deiry W.S. P53 and radiation responses. Oncogene 2003, 22:5774-5783.
20. Fuchs S.Y., Adler V., Buschmann T., Wu X., Ronai Z. Mdm2 association with p53 targets its ubiquitination. Oncogene 1998, 17:2543-2547.
21. Chen D., Zhang J., Li M., Rayburn E.R., Wang H., Zhang R. RYBP stabilizes p53 by modulating MDM2. Proceedings of the American Association for Cancer Research Annual Meeting 2009, 50:925-926.
22. Saville M.K., Sparks A., Xirodimas D.P., Wardrop J., Stevenson L.F., Bourdon J.C., Woods Y.L., Lane D.P. Regulation of p53 by the ubiquitin-conjugating enzymes UbcH5B/C in vivo. J. Biol. Chem. 2004, 279:42169-42181.
23. Haldeman M.T., Xia G., Kasperek E.M., Pickart C.M. Structure and function of ubiquitin conjugating enzyme E2-25K: the tail is a core-dependent activity element. Biochemistry 1997, 36:10526-10537.
24. Toettcher J.E., Loewer A., Ostheimer G.J., Yaffe M.B., Tidor B., Lahav G. Distinct mechanisms act in concert to mediate cell cycle arrest. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:785-790.
25. Kikuchi J., Furukawa Y., Kubo N., Tokura A., Hayashi N., Nakamura M., Matsuda M., Sakurabayashi I. Induction of ubiquitin-conjugating enzyme by aggregated low density lipoprotein in human macrophages and its implications for atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 2000, 20:128-134.