Upregulation of URI/RMP gene expression in cervical cancer by high-throughput tissue microarray analysis

International Journal of Clinical and Experimental Pathology

Volumn 6, Issue 4, 2013, Pages 669-677

  Gu, Junxia ^a   Li, Xiaoyun ^a   Liang, Yuting ^a   Qiao, Longwei ^a   Ran, Deyuan ^a   Lu, Yaojuan ^a,b   Li, Xingang ^c   Wei, Wenxiang ^d   Zheng, Qiping ^a,b  

^a JIANGSU UNIVERSITY   (China)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c Anyang Cancer Hospital   (China)

^d SOOCHOW UNIVERSITY   (China)

Author keywords

Cervical cancer; Immunohistochemistry; Tissue microarray; URI RMP

Indexed keywords

SIGNAL PEPTIDE; TUMOR MARKER; URI1 PROTEIN, HUMAN;

ARTICLE; CELL TRANSFORMATION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HIGH THROUGHPUT SCREENING; HUMAN; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; PHYSIOLOGY; PRECANCER; SQUAMOUS CELL CARCINOMA; TISSUE MICROARRAY; UPREGULATION; URI/RMP; UTERINE CERVIX; UTERINE CERVIX CANCER; UTERINE CERVIX CARCINOMA IN SITU; UTERINE CERVIX TUMOR;

CERVICAL CANCER; IMMUNOHISTOCHEMISTRY; TISSUE MICROARRAY; URI/RMP;

CARCINOMA, SQUAMOUS CELL; CELL TRANSFORMATION, NEOPLASTIC; CERVICAL INTRAEPITHELIAL NEOPLASIA; CERVIX UTERI; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PRECANCEROUS CONDITIONS; TISSUE ARRAY ANALYSIS; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION; UTERINE CERVICAL NEOPLASMS;

EID: 84882953751     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Dorjsuren D, Lin Y, Wei W, Yamashita T, Nomura T, Hayashi N, Murakami S. RMP, a novel RNA polymerase II subunit 5-interacting protein, counteracts transactivation by hepatitis B virus X protein. Mol Cell Biol 1998 Dec; 18: 7546-55.
2. Gstaiger M, Luke B, Hess D, Oakeley EJ, Wirbelauer C, Blondel M, Vigneron M, Peter M, Krek W. Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI. Science 2003 Nov 14; 302: 1208-12.
3. Delgermaa L, Hayashi N, Dorjsuren D, Nomura T, Thuy le TT, Murakami S. Subcellular localization of RPB5-mediating protein and its putative functional partner. Mol Cell Biol 2004 Oct; 24: 8556-66.
4. Yang H.,Gu J.,Zheng Q.,Li M.,Lian X.,Miao J.,Jiang J.,Wei W. RPB5-mediating protein is required for the proliferation of hepatocellular carcinoma cells. J Biol Chem 2011 Apr 1; 286: 11865-74.
5. Theurillat JP, Metzler SC, Henzi N, Djouder N, Helbling M, Zimmermann AK, Jacob F, Soltermann A, Caduff R, Heinzelmann-Schwarz V, Moch H, Krek W. URI is an oncogene amplified in ovarian cancer cells and is required for their survival. Cancer Cell 2011 Mar 8; 19: 317-32.
6. Sinicrope FA, Ruan SB, Cleary KR, Stephens LC, Lee JJ, Levin B. bcl-2 and p53 oncoprotein expression during colorectal tumorigenesis. Cancer Res 1995 Jan 15; 55: 237-41.
7. Wei W, Gu JX, Zhu CQ, Sun FY, Dorjsuren D, Lin Y, Murakami S. Interaction with general transcription factor IIF (TFIIF) is required for the suppression of activated transcription by RPB5-mediating protein (RMP). Cell Res 2003 Apr; 13: 111-20.
8. Parusel CT, Kritikou EA, Hengartner MO, Krek W, Gotta M. URI-1 is required for DNA stability in C. elegans. Development 2006 Feb; 133: 621-9.
9. Deplazes A, Möckli N, Luke B, Auerbach D, Peter M. Yeast Uri1p promotes translation initiation and may provide a link to cotranslational quality control. EMBO J 2009 May 20; 28: 1429-41.
10. Djouder N, Metzler SC, Schmidt A, Wirbelauer C, Gstaiger M, Aebersold R, Hess D, Krek W. S6K1-mediated disassembly of mitochondrial URI/PP1gamma complexes activates a negative feedback program that counters S6K1 survival signaling. Mol Cell 2007 Oct 12; 28: 28-40.
11. Guicciardi ME, Gores GJ. Cell stress gives a red light to the mitochondrial cell death pathway. Sci Signal 2008 Feb 19; 1: pe9.
12. Kirchner J, Vissi E, Gross S, Szoor B, Rudenko A, Alphey L, White-Cooper H. Drosophila Uri, a PP1alpha binding protein, is essential for viability, maintenance of DNA integrity and normal transcriptional activity. BMC Mol Biol 2008 Apr 15; 9: 36.
13. Boulon S, Pradet-Balade B, Verheggen C, Molle D, Boireau S, Georgieva M, Azzag K, Robert MC, Ahmad Y, Neel H, Lamond AI, Bertrand E. HSP90 and its R2TP/Prefoldin-like cochaperone are involved in the cytoplasmic assembly of RNA polymerase II. Mol Cell 2010 Sep 24; 39: 912-24.
14. Marchetti P, Bugliani M, Boggi U, Masini M, Marselli L. The pancreatic beta cells in human type 2 diabetes. Adv Exp Med Biol 2012; 771: 288-309.
15. Feldman BJ, Feldman D. The development of androgen-independent prostate cancer. Nat Rev Cancer 2001 Oct; 1: 34-45. Review.
16. Chen CD, Welsbie DS, Tran C, Baek SH, Chen R, Vessella R, Rosenfeld MG, Sawyers CL. Molecular determinants of resistance to antiandrogen therapy. Nat Med 2004 Jan; 10: 33-9. Epub 2003 Dec 21.
17. Mita P, Savas JN, Djouder N, Yates JR 3rd, Ha S, Ruoff R, Schafler ED, Nwachukwu JC, Tanese N, Cowan NJ, Zavadil J, Garabedian MJ, Logan SK. Regulation of androgen receptor-mediated transcription by RPB5 binding protein URI/RMP. Mol Cell Biol 2011 Sep; 31: 3639-52.
18. Park J, Sun D, Genest DR, Trivijitsilp P, Suh I, Crum CP. Coexistence of low and high grade squamous intraepithelial lesions of the cervix: morphologic progression or multiple papillomaviruses? Gynecol Oncol 1998 Sep; 70: 386-91.
19. Agorastos T, Miliaras D, Lambropoulos AF, Chrisafi S, Kotsis A, Manthos A, Bontis J. Detection and typing of human papillomavirus DNA in uterine cervices with coexistent grade I and grade III intraepithelial neoplasia: biologic progression or independent lesions? Eur J Obstet Gynecol Reprod Biol 2005 Jul 1; 121: 99-103.
20. Duensing S, Münger K. Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins. Int J Cancer 2004 Mar 20; 109: 157-62. Review.
21. Dehn D, Torkko KC, Shroyer KR. Human papillomavirus testing and molecular markers of cervical dysplasia and carcinoma. Cancer 2007 Feb 25; 111: 1-14. Review.
22. Scotto L, Narayan G, Nandula SV, Arias-Pulido H, Subramaniyam S, Schneider A, Kaufmann AM, Wright JD, Pothuri B, Mansukhani M, Murty VV. Identification of copy number gain and overexpressed genes on chromosome arm 20q by an integrative genomic approach in cervical cancer: potential role in progression. Genes Chromosomes Cancer 2008 Sep; 47: 755-65.
23. McLaughlin-Drubin ME, Münger K. The human papillomavirus E7 oncoprotein. Virology 2009 Feb 20; 384: 335-44.
24. Gouveris P, Weinberger PM, Psyrri A. Use of tissue microarray to facilitate oncology research. Methods Mol Biol 2010; 632: 239-50.
25. Molinolo AA, Marsh C, El Dinali M, Gangane N, Jennison K, Hewitt S, Patel V, Seiwert TY, Gutkind JS. mTOR as a molecular target in HPV-associated oral and cervical squamous carcinomas. Clin Cancer Res 2012 May 1; 18: 2558-68.