Large Conductance Calcium-Activated Potassium Channels

Encyclopedia of Neuroscience

Volumn , Issue , 2009, Pages 373-381

  Alioua, A ^a   Kundu, P ^a   Lu, R ^a   Kumar, Y ^a   Ou, J ^a   Stefani, E ^a   Toro, L ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

BK; Channelopathy; KCNMA1; KCNMB; Knockout; Macromolecular complexes; MaxiK; Neurons; Neuroprotection; Neurotransmitter release; Neurovascular; Potassium channel; Slo1; subunits

Indexed keywords

EID: 84882866054     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-008045046-9.01632-6     Document Type: Chapter

References (15)

1. Brenner R., Chen Q.H., Vilaythong A., Toney G.M., Noebels J.L., Aldrich R.W. BK channel beta4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures. Nature Neuroscience 2005, 8:1752-1759.
2. Du W., Bautista J.F., Yang H., et al. Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder. Nature Genetics 2005, 37:733-738.
3. Filosa J.A., Bonev A.D., Straub S.V., et al. Local potassium signaling couples neuronal activity to vasodilation in the brain. Nature Neuroscience 2006, 9:1397-1403.
4. Gribkoff V.K., Starrett J.E., Dworetzky S.I. Maxi-K potassium channels: Form, function, and modulation of a class of endogenous regulators of intracellular calcium. Neuroscientist 2001, 7:166-177.
5. Gu N., Vervaeke K., Storm J.F. BK potassium channels facilitate high-frequency firing and cause early spike frequency adaptation in rat CA1 hippocampal pyramidal cells. Journal of Physiology 2007, 580:859-882.
6. Lu R., Alioua A., Kumar Y., Eghbali M., Stefani E., Toro L. KCa1.1 channel partners: Physiological impact. Journal of Physiology 2006, 570:65-72.
7. + channel resistant to charybdotoxin and iberiotoxin. Proceedings of the National Academy of Sciences of the United States of America 2000, 97:5562-5567.
8. Meredith A.L., Wiler S.W., Miller B.H., et al. BK calcium-activated potassium channels regulate circadian behavioral rhythms and pacemaker output. Nature Neuroscience 2006, 9:1041-1049.
9. Orio P., Rojas P., Ferreira G., Latorre R. New disguises for an old channel: KCa1.1 channel beta-subunits. News in Physiological Sciences 2002, 17:156-161.
10. Runden-Pran E., Haug F.M., Storm J.F., Ottersen O.P. BK channel activity determines the extent of cell degeneration after oxygen and glucose deprivation: A study in organotypical hippocampal slice cultures. Neuroscience 2002, 112:277-288.
11. 2+-activated potassium (BK) alpha-subunit but not the BKbeta1-subunit leads to progressive hearing loss. Proceedings of the National Academy of Sciences of the United States of America 2004, 101:12922-12927.
12. + channel deficiency. Proceedings of the National Academy of Sciences of the United States of America 2004, 101:9474-9478.
13. + channels of the BK-type in the mouse brain. Histochemistry and Cell Biology 2006, 125:725-741.
14. + channels: A transmembrane β-subunit homolog. Proceedings of the National Academy of Sciences of the United States of America 1999, 96:4137-4142.
15. + channel. Neuroscience 2007, 147:80-89.