Involvement of unfolded protein response, p53 and Akt in modulation of porcine reproductive and respiratory syndrome virus-mediated JNK activation

Virology

Volumn 444, Issue 1-2, 2013, Pages 233-240

  Huo, Yazhen ^a   Fan, Lihong ^a   Yin, Shutao ^a   Dong, Yinhui ^a   Guo, Xiao ^a   Yang, Hanchun ^a   Hu, Hongbo ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

Akt; Apoptosis; JNK; P53; PRRSV; Unfolded protein response (UPR)

Indexed keywords

PROTEIN IRE1; PROTEIN KINASE B; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; APOPTOSIS; ARTERIVIRUS INFECTION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; VIRUS CELL INTERACTION; VIRUS REPLICATION;

AKT; APOPTOSIS; JNK; P53; PRRSV; UNFOLDED PROTEIN RESPONSE (UPR);

ANIMALS; APOPTOSIS; CELL LINE; CERCOPITHECUS AETHIOPS; MAP KINASE SIGNALING SYSTEM; PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; UNFOLDED PROTEIN RESPONSE;

PORCINE RESPIRATORY AND REPRODUCTIVE SYNDROME VIRUS;

EID: 84882830182     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2013.06.015     Document Type: Article

References (36)

1. Amin A.R., Thakur V.S., Gupta K., Jackson M.W., Harada H., et al. Restoration of p53 functions protects cells from concanavalin A-induced apoptosis. Mol. Cancer Ther. 2010, 9(2):471-479.
2. Arslan S.Y., Son K.N., Lipton H.L. The antiapoptotic protein Mcl-1 controls the type of cell death in Theiler's virus-infected BHK-21 cells. J. Virol. 2012, 86(4):1922-1929.
3. Costers S., Lefebvre D.J., Delputte P.L., Nauwynck H.J. Porcine reproductive and respiratory syndrome virus modulates apoptosis during replication in alveolar macrophages. Arch. Virol. 2008, 153(8):1453-1465.
4. Garner E., Raj K. Protective mechanisms of p53-p21-pRb proteins against DNA damage-induced cell death. Cell Cycle 2007, 7(3):277-282.
5. Hassan I.H., Zhang M.S., Powers L.S., Shao J.Q., Baltrusaitis J., et al. Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway. J. Biol. Chem. 2012, 287(7):4679-4689.
6. Haupt S., Berger M., Goldberg Z., Haupt Y. Apoptosis-the p53 network. J. Cell Sci. 2003, 116(Pt 20):4077-4085.
7. Huang H.L., Wu J.L., Chen M.H., Hong J.R. Aquatic birnavirus-induced ER stress-mediated death signaling contribute to downregulation of Bcl-2 family proteins in salmon embryo cells. PLoS One 2011, 6(8):e22935.
8. Huang Z.M., Tan T., Yoshida H., Mori K., Ma Y., et al. Activation of hepatitis B virus S promoter by a cell type-restricted IRE1-dependent pathway induced by endoplasmic reticulum stress. Mol. Cell Biol. 2005, 25(17):7522-7533.
9. Karniychuk U.U., Saha D., Geldhof M., Vanhee M., Cornillie P., et al. Porcine reproductive and respiratory syndrome virus (PRRSV) causes apoptosis during its replication in fetal implantation sites. Microb. Pathog. 2011, 51(3):194-202.
10. Kim H.S., Kwang J., Yoon I.J., Joo H.S., Frey M.L. Enhanced replication of porcine reproductive and respiratory syndrome (PRRS) virus in a homogeneous subpopulation of MA-104 cell line. Arch. Virol. 1993, 133(3-4):477-483.
11. Li J., Yin S., Dong Y., Fan L., Hu H. p53 activation inhibits ochratoxin A-induced apoptosis in monkey and human kidney epithelial cells via suppression of JNK activation. Biochem. Biophys. Res. Commun. 2011, 411(2):458-4563.
12. Liu X., Li Q., Dowdell K., Fischer E.R., Cohen J.I. Varicella-Zoster virus ORF12 protein triggers phosphorylation of ERK1/2 and inhibits apoptosis. J. Virol. 2012, 86(6):3143-3151.
13. Lu X., Masic A., Li Y., Shin Y., Liu Q., et al. The PI3K/Akt pathway inhibits influenza A virus-induced Bax-mediated apoptosis by negatively regulating the JNK pathway via ASK1. J. Gen. Virol. 2010, 91(Pt 6):1439-1449.
14. Lunney J.K., Benfield D.A., Rowland R.R. Porcine reproductive and respiratory syndrome virus: an update on an emerging and re-emerging viral disease of swine. Virus. Res. 2010, 154(1-2):1-6.
15. Mahoney D.J., Lefebvre C., Allan K., Brun J., Sanaei C.A., et al. Virus-tumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-triggered caspase-2 cell death. Cancer Cell 2011, 20(4):443-456.
16. Mercer J., Bennett M. The role of p53 in atherosclerosis. Cell Cycle 2006, 5(17):1907-1909.
17. Nguyen H., Sankaran S., Dandekar S. Hepatitis C virus core protein induces expression of genes regulating immune evasion and anti-apoptosis in hepatocytes. Virology 2006, 354(1):58-68.
18. Nishitoh H., Matsuzawa A., Tobiume K., Saegusa K., Takeda K., et al. ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev. 2002, 16(11):1345-1355.
19. Patel R.K., Hardy R.W. Role for the phosphatidylinositol 3-kinase-Akt-TOR pathway during sindbis virus replication in arthropods. J. Virol. 2012, 86(7):3595-3604.
20. Reed L.I., Muench H. A simple method of estimating fifty per cent endpoints. Am. J. Hyg. 1938, 27:493-497.
21. Roberson E.C., Tully J.E., Guala A.S., Reiss J.N., Godburn K.E., et al. Influenza induces endoplasmic reticulum stress, caspase-12-dependent apoptosis, and c-Jun N-terminal kinase-mediated transforming growth factor-β release in lung epithelial cells. Am. J. Respir. Cell Mol. Biol. 2012, 46(5):573-581.
22. Rodrigues R., Paranhos-Baccalà G., Vernet G., Peyrefitte C.N. Crimean-Congo hemorrhagic fever virus-infected hepatocytes induce ER-stress and apoptosis crosstalk. PLoS One 2012, 7(1):e29712.
23. Rosebeck S., Sudini K., Chen T., Leaman D.W. Involvement of Noxa in mediating cellular ER stress responses to lytic virus infection. Virology 2011, 417(2):293-303.
24. Sharma-Walia N., Paul A.G., Bottero V., Sadagopan S., Veettil M.V., et al. Kaposi's sarcoma associated herpes virus (KSHV) induced COX-2: a key factor in latency, inflammation, angiogenesis, cell survival and invasion. PLoS Pathog. 2010, 6(2):e1000777.
25. Suarez P. Ultrastructural pathogenesis of the PRRS virus. Vet. Res. 2000, 31:47-55.
26. Tabas I., Ron D. Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress. Nat. Cell Biol. 2011, 13(3):184-190.
27. Urata S., Ngo N., de la Torre J.C. The PI3K/Akt pathway contributes to arenavirus budding. J. Virol. 2012, 86(8):4578-4585.
28. Vogelstein B., Lane D., Levine A.J. Surfing the p53 network. Nature 2000, 408:307-310.
29. Volkmann K., Lucas J.L., Vuga D, Wang X., Brumm D., et al. Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease. J. Biol. Chem. 2011, 286(14):12743-12755.
30. Walter P., Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science 2011, 334(6059):1081-1086.
31. Wang Q., Chen J., Wang Y., Han X., Chen X. Hepatitis C virus induced a novel apoptosis-like death of pancreatic beta cells through a caspase 3-dependent pathway. PLoS One 2012, 7(6):e38522. 10.1371/journal.pone.0038522.
32. Wei L., Zhu S., Wang J., Liu J. Activation of the PI3K/Akt signaling pathway during porcine circovirus type 2-infection facilitates cell survival and viral replication. J. Virol. 2012, 86(24):13589-13597.
33. Yamagishi N., Miyakoshi J., Yagi T., Takebe H. Suppression of UV-induced mutations by wild-type p53 protein in human osteosarcoma cells. Mutagenesis 1997, 12:191-194.
34. Ye Z., Wong C.K., Li P., Xie Y. A SARS-CoV protein, ORF-6, induces caspase-3 mediated, ER stress and JNK-dependent apoptosis. Biochim. Biophys. Acta 2008, 1780(12):1383-1387.
35. Yin S., Huo Y., Dong Y., Fan L., Yang H., et al. Activation of c-Jun NH(2)-terminal kinase is required for porcine reproductive and respiratory syndrome virus-induced apoptosis but not for virus replication. Virus. Res. 2012, 166(1-2):103-108.
36. Zhang H., Wang X. A dual effect of porcine reproductive and respiratory syndrome virus replication on the phosphatidylinositol-3-kinase-dependent Akt pathway. Arch. Virol. 2010, 155(4):571-575.