A rapid and simple chromatographic separation of diastereomers of silibinin and their oxidation to produce 2,3-dehydrosilybin enantiomers in an optically pure form

Planta Medica

Volumn 79, Issue 12, 2013, Pages 1077-1080

  Di Fabio, Giovanni ^a   Romanucci, Valeria ^a   Di Marino, Cinzia ^a   De Napoli, Lorenzo ^a   Zarrelli, Armando ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

2,3 dehydrosilybin; Asteraceae; flavonolignans; prep RP HPLC; silibinin; silybin A; silybin B; Silybum marianum

Indexed keywords

2,3 DEHYDROSILYBIN A; 2,3 DEHYDROSILYBIN B; METHANOL; SILIBININ; SILIBININ A; SILIBININ B; SOLVENT; UNCLASSIFIED DRUG; WATER;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; COMEDO; DIASTEREOISOMER; DRUG SOLUBILITY; ELECTROSPRAY MASS SPECTROMETRY; ENANTIOMER; OXIDATION; PARTICLE SIZE; PHYSICAL CHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ASTERACEAE; SILYBUM MARIANUM;

ANTIOXIDANTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MILK THISTLE; OXIDATION-REDUCTION; SILYMARIN; STEREOISOMERISM;

EID: 84882829574     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0032-1328703     Document Type: Article

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