TRPM6: A janus-like protein

Handbook of Experimental Pharmacology

Volumn 179, Issue , 2007, Pages 299-311

  Bodding M ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

Hypomagnesaemia with secondary hypocalcaemia (HSH); Magnesium absorption; Melastatin; Transient receptor potential (TRP) channel; TRPM6; TRPM7

Indexed keywords

ION CHANNEL; PHOSPHOTRANSFERASE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM6 PROTEIN, HUMAN; TRPM6 PROTEIN, RAT; UNCLASSIFIED DRUG;

ANIMAL; BIOTRANSFORMATION; CHEMISTRY; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; PHYSIOLOGY; REVIEW; TISSUE DISTRIBUTION;

ANIMALS; BIOTRANSFORMATION; HUMANS; ION CHANNELS; PHOSPHOTRANSFERASES; TISSUE DISTRIBUTION; TRPM CATION CHANNELS;

EID: 84882829180     PISSN: 01712004     EISSN: 18650325     Source Type: Book Series    
DOI: 10.1007/978-3-540-34891-7_18     Document Type: Article

References (54)

1. Aarts M, Iihara K, Wei WL, Xiong ZG, Arundine M, Cerwinski W, MacDonald JF, TymianskiM( 2003) A key role for TRPM7 channels in anoxic neuronal death. Cell 115:863-877
2. AbdulrazzaqYM,Smigura FC,WettrellG(1989)Primary infantilehypomagnesaemia; report of two cases and review of literature. Eur J Pediatr 148:459-461
3. Caterina MJ, Schumacher MA, Tominaga M, Rosen TA, Levine JD, Julius D (1997) The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389:816-824
4. Challa A, Papaefstathiou I, Lapatsanis D, Tsolas O (1995) Primary idiopathic hypomagnesemia in two female siblings. Acta Paediatr 84:1075-1078
5. Chery M, Biancalana V, Philippe C, Malpuech G, Carla H, Gilgenkrantz S, Mandel JL, Hanauer A (1994) Hypomagnesemia with secondary hypocalcemia in a female with balanced X;9 translocation: mapping of the Xp22 chromosome breakpoint. Hum Genet 93:587-591
6. Chubanov V,Waldegger S, Mederos y Schnitzler M, Vitzthum H, Sassen MC, Seyberth HW, Konrad M, Gudermann T (2004) Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia. Proc Natl Acad Sci U S A 101:2894-2899
7. Chubanov V, Schlingmann KP, Waring J, Mederos y Schnitzler M, Waldegger S, GudermannT( 2006)Dominat-negativer Effekt einer neuenMissensmutation immenschlichen TRPM6-Gen führt zu Hypomagnesiämie mit sekundären Hypokalzämie. Naunyn Schmiedebergs Arch Pharmacol 372:60
8. DorovkovMV,RyazanovAG(2004) Phosphorylationof annexin I byTRPM7channel-kinase. J Biol Chem 279:50643-50646
9. Ehrlich BE, Kaftan E, Bezprozvannaya S, Bezprozvanny I (1994) The pharmacology of intracellular Ca2+-release channels. Trends Pharmacol Sci 15:145-149
10. Groenestege WM, Hoenderop JG, van den Heuvel L, Knoers N, Bindels RJ (2006) The epithelial Mg2+ channel transient receptor potential melastatin 6 is regulated by dietary Mg2+ content and estrogens. J Am Soc Nephrol 17:1035-1043
11. Gwanyanya A, Amuzescu B, Zakharov SI, Macianskiene R, Sipido KR, Bolotina VM, Vereecke J, Mubagwa K (2004) Magnesium-inhibited, TRPM6/7-like channel in cardiac myocytes: permeation of divalent cations and pH-mediated regulation. J Physiol 559:761-776
12. Hanano T, Hara Y, Shi J, Morita H, Umebayashi C, Mori E, Sumimoto H, Ito Y, Mori Y, Inoue R (2004) Involvement of TRPM7 in cell growth as a spontaneously activated Ca2+ entry pathway in human retinoblastoma cells. J Pharmacol Sci 95:403-419
13. Hermosura MC, Monteilh-Zoller MK, Scharenberg AM, Penner R, Fleig A (2002) Dissociation of the store-operated calcium current I(CRAC) and the Mg-nucleotide-regulated metal ion current MagNuM. J Physiol 539:445-458
14. Hoenderop JG, van der Kemp AW, Hartog A, van de Graaf SF, van Os CH, Willems PH, Bindels RJ (1999)Molecular identification of the apical Ca2+ channel in 1, 25-dihydroxyvitamin D3-responsive epithelia. J Biol Chem 274:8375-8378
15. Hoenderop JG, Voets T, Hoefs S, Weidema F, Prenen J, Nilius B, Bindels RJ (2003) Homoand heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6. EMBO J 22:776-785
16. Hu HZ, Gu Q,Wang C, Colton CK, Tang J, Kinoshita-Kawada M, Lee LY,Wood JD, Zhu MX (2004) 2-Aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3. J Biol Chem 279:35741-35748
17. Kayne LH,LeeDB(1993) Intestinalmagnesiumabsorption. MinerElectrolyteMetab19:210-217
18. Konrad M,Weber S (2003) Recent advances in molecular genetics of hereditarymagnesiumlosing disorders. J Am Soc Nephrol 14:249-260
19. Kozak JA, Cahalan MD (2003) MIC channels are inhibited by internal divalent cations but not ATP. Biophys J 84:922-927
20. Kozak JA, Kerschbaum HH, Cahalan MD (2002) Distinct properties of CRAC and MIC channels in RBL cells. J Gen Physiol 120:221-235
21. Lee CT, Lien YH, Lai LW, Chen JB, Lin CR, Chen HC (2006) Increased renal calcium and magnesium transporter abundance in streptozotocin-induced diabetes mellitus. Kidney Int 69:1786-1791
22. Luft JH (1971) Ruthenium red and violet. II. Fine structural localization in animal tissues. Anat Rec 171:369-415
23. Maruyama T, Kanaji T, Nakade S, Kanno T, Mikoshiba K (1997) 2APB, 2-aminoethoxydiphenyl borate, a membrane-penetrable modulator of Ins(1,4,5)P3-induced Ca2+ release. J Biochem (Tokyo) 122:498-505
24. Meyer P, Boettger MB (2001) Familial hypomagnesaemia with secondary hypocalcaemia: a new case that indicates autosomal recessive inheritance. J InheritMetabDis 24:875-876
25. Nadler MJ, Hermosura MC, Inabe K, Perraud AL, Zhu Q, Stokes AJ, Kurosaki T, Kinet JP, Penner R, Scharenberg AM, FleigA(2001) LTRPC7 is aMg.ATP-regulated divalent cation channel required for cell viability. Nature 411:590-595
26. Nijenhuis T, Hoenderop JG, Bindels RJ (2004) Downregulation of Ca2+ and Mg2+ transport proteins in the kidney explains tacrolimus (FK506)-induced hypercalciuria and hypomagnesemia. J Am Soc Nephrol 15:549-557
27. Nijenhuis T, Renkema KY, Hoenderop JG, Bindels RJ (2006) Acid-base status determines the renal expression of Ca2+ and Mg2+ transport proteins. J AmSoc Nephrol 17:617-626
28. Nilius B, Prenen J, Vennekens R, Hoenderop JG, Bindels RJ, Droogmans G (2001) Pharmacologicalmodulation ofmonovalent cation currents through the epithelial Ca2+ channel ECaC1. Br J Pharmacol 134:453-462
29. Nilius B, Prenen J, Droogmans G, Voets T, Vennekens R, Freichel M, Wissenbach U, Flockerzi V (2003) Voltage dependence of the Ca2+-activated cation channel TRPM4. J Biol Chem 278:30813-30820
30. Nilius B, Talavera K, Owsianik G, Prenen J, Droogmans G, Voets T (2005a) Gating of TRP channels: a voltage connection?. J Physiol 567:35-44
31. Nilius B, Voets T, Peters J (2005b) TRP channels in disease. Sci STKE 2005:eg7
32. Paunier L, Radde IC, Kooh SW, Conen PE, Fraser D (1968) Primary hypomagnesemia with secondary hypocalcemia in an infant. Pediatrics 41:385-402
33. Peng JB, Chen XZ, Berger UV, Vassilev PM, Tsukaguchi H, Brown EM, Hediger MA (1999) Molecular cloning and characterization of a channel-like transporter mediating intestinal calcium absorption. J Biol Chem 274:22739-22746
34. PerrettiM, Solito E (2004) Annexin 1 and neutrophil apoptosis. Biochem Soc Trans 32:507-510
35. Prakriya M, Lewis RS (2002) Separation and characterization of currents through storeoperated CRAC channels and Mg2+-inhibited cation (MIC) channels. J Gen Physiol 119:487-507
36. Pronicka E, Gruszczynska B (1991) Familial hypomagnesaemia with secondary hypocalcaemia-autosomal or X-linked inheritance?. J Inherit Metab Dis 14:397-399
37. Riazanova LV, Pavur KS, Petrov AN, Dorovkov MV, Riazanov AG (2001) Novel type of signaling molecules: protein kinases covalently linked to ion channels (in Russian).Mol Biol (Mosk) 35:321-332
38. Runnels LW, Yue L, Clapham DE (2001) TRP-PLIK, a bifunctional protein with kinase and ion channel activities. Science 291:1043-1047
39. Runnels LW, Yue L, Clapham DE (2002) The TRPM7 channel is inactivated by PIP(2) hydrolysis. Nat Cell Biol 4:329-336
40. Ryazanova LV, Dorovkov MV, Ansari A, Ryazanov AG (2004) Characterization of the protein kinase activity of TRPM7/ChaK1, a protein kinase fused to the transient receptor potential ion channel. J Biol Chem 279:3708-3716
41. Schlingmann KP, Weber S, Peters M, Niemann Nejsum L, Vitzthum H, Klingel K, Kratz M, Haddad E, RistoffE,DinourD, Syrrou M,Nielsen S, Sassen M,Waldegger S, SeyberthHW, KonradM(2002)Hypomagnesemiawith secondaryhypocalcemia is causedbymutations in TRPM6, a new member of the TRPM gene family. Nat Genet 31:166-170
42. Schmitz C, Perraud AL, Johnson CO, Inabe K, Smith MK, Penner R, Kurosaki T, Fleig A, Scharenberg AM (2003) Regulation of vertebrate cellular Mg2+ homeostasis by TRPM7. Cell 114:191-200
43. Schweigel M, Martens H (2000) Magnesium transport in the gastrointestinal tract. Front Biosci 5:D666-D677
44. Strübing C, Krapivinsky G, Krapivinsky L, Clapham DE (2001) TRPC1 and TRPC5 form a novel cation channel in mammalian brain. Neuron 29:645-655
45. Talavera K, Yasumatsu K, Voets T, Droogmans G, Shigemura N, Ninomiya Y,Margolskee RF, Nilius B (2005) Heat activation of TRPM5 underlies thermal sensitivity of sweet taste. Nature 438:1022-1025
46. Visudhiphan P,Visudtibhan A, Chiemchanya S,KhongkhatithumC(2005)Neonatal seizures and familial hypomagnesemia with secondary hypocalcemia. PediatrNeurol 33:202-205
47. Voets T, Prenen J, Vriens J, Watanabe H, Janssens A, Wissenbach U, Bödding M, Droogmans G, Nilius B (2002) Molecular determinants of permeation through the cation channel TRPV4. J Biol Chem 277:33704-33710
48. Voets T, Nilius B, Hoefs S, van der Kemp AW, Droogmans G, Bindels RJ, Hoenderop JG (2004) TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption. J Biol Chem 279:19-25
49. Walder RY, Shalev H, Brennan TM, Carmi R, Elbedour K, Scott DA, Hanauer A, Mark AL, Patil S, Stone EM, Sheffield VC (1997) Familial hypomagnesemia maps to chromosome 9q, not to the X chromosome: genetic linkage mapping and analysis of a balanced translocation breakpoint. Hum Mol Genet 6:1491-1497
50. Walder RY, Landau D, Meyer P, Shalev H, Tsolia M, Borochowitz Z, Boettger MB, Beck GE, Englehardt RK, Carmi R, Sheffield VC (2002) Mutation of TRPM6 causes familial hypomagnesemia with secondary hypocalcemia. Nat Genet 31:171-174
51. Wu SN, Jan CR, Li HF (1999) Ruthenium red-mediated inhibition of large-conductance Ca2+-activated K+ channels in rat pituitary GH3 cells. J Pharmacol Exp Ther 290:998-1005
52. Xu SZ, Zeng F, Boulay G, Grimm C, Harteneck C, Beech DJ (2005) Block of TRPC5 channels by 2-aminoethoxydiphenyl borate: a differential, extracellular and voltage-dependent effect. Br J Pharmacol 145:405-414
53. Yamaguchi H, Matsushita M, Nairn AC, Kuriyan J (2001) Crystal structure of the atypical protein kinase domain of a TRP channel with phosphotransferase activity. Mol Cell 7:1047-1057
54. Yamamoto T, Kabata H, Yagi R, Takashima M, Itokawa Y (1985) Primary hypomagnesemia with secondary hypocalcemia. Report of a case and review of the world literature. Magnesium 4:153-164