Pro-apoptotic signaling induced by photo-oxidative ER stress is amplified by Noxa, not Bim

Biochemical and Biophysical Research Communications

Volumn 438, Issue 3, 2013, Pages 500-506

  Verfaillie, Tom ^a   van Vliet, Alexander ^a   Garg, Abhishek D ^a   Dewaele, Michael ^a   Rubio, Noemi ^a   Gupta, Sanjeev ^c   de Witte, Peter ^b   Samali, Afshin ^c   Agostinis, Patrizia ^a  

^a LABORATORY OF MOLECULAR AND CELLULAR SIGNALING   (Belgium)

^b UNIVERSITY OF LEUVEN   (Belgium)

^c NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Apoptosis; Bim; Bladder cancer; Cell death; Endoplasmic reticulum stress; Hypericin; PERK; Photodynamic therapy (PDT)

Indexed keywords

BIM PROTEIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HYPERICIN; PROTEIN MCL 1; PROTEIN NOXA;

APOPTOSIS; ARTICLE; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; BIM; BLADDER CANCER; C/EBP HOMOLOGOUS PROTEIN; CELL DEATH; CHOP; EIF2A; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; ER; EUKARYOTIC INITIATION FACTOR-2A; GLUCOSE REGULATED PROTEIN 78; GRP78; HYP-PDT; HYPERICIN; HYPERICIN-BASED PHOTODYNAMIC THERAPY; ICD; IMMUNOGENIC CELL DEATH; MEF; MURINE EMBRYONIC FIBROBLAST; PANCREATIC ER KINASE (PKR)-LIKE ER KINASE; PERK; PHOTO-OXIDATIVE; PHOTODYNAMIC THERAPY (PDT); PHOX; REACTIVE OXYGEN SPECIES; ROS; UNFOLDED PROTEIN RESPONSE; UPR;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; HUMANS; MEMBRANE PROTEINS; MICE; PERYLENE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 84882825448     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.07.107     Document Type: Article

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