Women, kidney disease, and pregnancy

Advances in Chronic Kidney Disease

Volumn 20, Issue 5, 2013, Pages 402-410

  Smyth, Andrew ^a,b,c   Radovic, Milan ^a,b,c   Garovic, Vesna D ^a,b,c  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b UNIVERSITY OF BELGRADE   (Serbia)

^c MAYO CLINIC   (United States)

Author keywords

Glomerular disease; Kidney disease; Preeclampsia; Pregnancy; Proteinuria

Indexed keywords

ACETYLSALICYLIC ACID; ANTIHYPERTENSIVE AGENT; AZATHIOPRINE; BLOOD CLOTTING FACTOR 10A INHIBITOR; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN; HEPARIN; HYDROXYCHLOROQUINE; IMMUNOGLOBULIN; IMMUNOSUPPRESSIVE AGENT; LOW MOLECULAR WEIGHT HEPARIN; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; RITUXIMAB; TACROLIMUS; THROMBIN INHIBITOR; WARFARIN;

ADAPTIVE IMMUNITY; ANTICOAGULANT THERAPY; AORTA ARCH SYNDROME; BLOOD PRESSURE REGULATION; CARDIOVASCULAR RISK; CESAREAN SECTION; CREATININE BLOOD LEVEL; DIABETIC NEPHROPATHY; DIFFERENTIAL DIAGNOSIS; EMBRYOTOXICITY; FETOTOXICITY; FETUS GROWTH; FETUS WASTAGE; FIRST TRIMESTER PREGNANCY; FOCAL GLOMERULOSCLEROSIS; GLOMERULOPATHY; GLOMERULUS BASEMENT MEMBRANE; GLOMERULUS FILTRATION RATE; HEART OUTPUT; HEMOLYTIC UREMIC SYNDROME; HUMAN; HYDRONEPHROSIS; HYPERCOAGULABILITY; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOSUPPRESSIVE TREATMENT; INNATE IMMUNITY; INSULIN DEPENDENT DIABETES MELLITUS; KIDNEY BIOPSY; KIDNEY BLOOD FLOW; KIDNEY DISEASE; LUPUS ERYTHEMATOSUS NEPHRITIS; MATERNAL DISEASE; MATERNAL MORTALITY; MEMBRANOUS GLOMERULONEPHRITIS; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PREECLAMPSIA; PREGNANCY; PREGNANCY COMPLICATION; PREGNANCY DISORDER; PREGNANCY OUTCOME; PREMATURE LABOR; PRIORITY JOURNAL; PROTEINURIA; REVIEW; SCLERODERMA; SMOOTH MUSCLE RELAXATION; SYSTEMIC LUPUS ERYTHEMATOSUS; SYSTEMIC SCLEROSIS; TERATOGENICITY; TH1 CELL; TH2 CELL; VASCULITIS;

GLOMERULAR DISEASE; KIDNEY DISEASE; PREECLAMPSIA; PREGNANCY; PROTEINURIA;

ANTIPHOSPHOLIPID SYNDROME; DIABETIC NEPHROPATHIES; FEMALE; GLOMERULONEPHRITIS; HEMOLYTIC-UREMIC SYNDROME; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY DISEASES; LUPUS NEPHRITIS; NEPHROSIS, LIPOID; PREGNANCY; PREGNANCY COMPLICATIONS; SCLERODERMA, SYSTEMIC; VASCULITIS;

EID: 84882758111     PISSN: 15485595     EISSN: 15485609     Source Type: Journal    
DOI: 10.1053/j.ackd.2013.06.004     Document Type: Review

References (82)

1. Fischer M.J. Chronic kidney disease and pregnancy: maternal and fetal outcomes. Adv Chronic Kidney Dis 2007, 14(2):132-145.
2. Kong N.C. Pregnancy of a lupus patient-a challenge to the nephrologist. Nephrol Dial Transplant 2006, 21(2):268-272.
3. Cunningham F., Leveno K., Bloom S., Hauth J., Rouse D., Spong C. Maternal Physiology. Williams Obstetrics 2010, McGraw-Hill, New York, NY. 23rd ed.
4. Davison J.M., Dunlop W. Renal hemodynamics and tubular function normal human pregnancy. Kidney Int 1980, 18(2):152-161.
5. Roberts M., Lindheimer M.D., Davison J.M. Altered glomerular permselectivity to neutral dextrans and heteroporous membrane modeling in human pregnancy. Am J Physiol 1996, 270(2 Pt 2):F338-F343.
6. Higby K., Suiter C.R., Phelps J.Y., Siler-Khodr T., Langer O. Normal values of urinary albumin and total protein excretion during pregnancy. Am J Obstet Gynecol 1994, 171(4):984-989.
7. Hou S. Pregnancy in chronic renal insufficiency and end-stage renal disease. Am J Kidney Dis 1999, 33(2):235-252.
8. Aluvihare V.R., Kallikourdis M., Betz A.G. Regulatory T cells mediate maternal tolerance to the fetus. Nat Immunol 2004, 5(3):266-271.
9. Saito S., Sakai M., Sasaki Y., Tanebe K., Tsuda H., Michimata T. Quantitative analysis of peripheral blood Th0, Th1, Th2 and the Th1:Th2 cell ratio during normal human pregnancy and preeclampsia. Clin Exp Immunol 1999, 117(3):550-555.
10. Zen M., Ghirardello A., Iaccarino L., et al. Hormones, immune response, and pregnancy in healthy women and SLE patients. Swiss Med Wkly 2010, 140(13-14):187-201.
11. Clark C.A., Spitzer K.A., Laskin C.A. Decrease in pregnancy loss rates in patients with systemic lupus erythematosus over a 40-year period. J Rheumatol 2005, 32(9):1709-1712.
12. Hochberg M.C. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1997, 40(9):1725.
13. Clowse M.E., Jamison M., Myers E., James A.H. A national study of the complications of lupus in pregnancy. Am J Obstet Gynecol 2008, 199(2). 127.e1-e6.
14. Ritchie J., Smyth A., Tower C., Helbert M., Venning M., Garovic V.D. Maternal deaths in women with lupus nephritis: a review of published evidence. Lupus 2012, 21(5):534-541.
15. Wagner S.J., Craici I., Reed D., et al. Maternal and foetal outcomes in pregnant patients with active lupus nephritis. Lupus 2009, 18(4):342-347.
16. Ramsey-Goldman R., Kutzer J.E., Kuller L.H., Guzick D., Carpenter A.B., Medsger T.A. Previous pregnancy outcome is an important determinant of subsequent pregnancy outcome in women with systemic lupus erythematosus. Am J Reprod Immunol 1992, 28(3-4):195-198.
17. Smyth A., Oliveira G.H., Lahr B.D., Bailey K.R., Norby S.M., Garovic V.D. A systematic review and meta-analysis of pregnancy outcomes in patients with systemic lupus erythematosus and lupus nephritis. Clin J Am Soc Nephrol 2010, 5(11):2060-2068.
18. Carmona F., Font J., Moga I., et al. Class III-IV proliferative lupus nephritis and pregnancy: a study of 42 cases. Am J Reprod Immunol 2005, 53(4):182-188.
19. Stanhope T.J., White W.M., Moder K.G., Smyth A., Garovic V.D. Obstetric nephrology: lupus and lupus nephritis in pregnancy. Clin J Am Soc Nephrol 2012, 7(12):2089-2099.
20. McNeil H.P., Chesterman C.N., Krilis S.A. Immunology and clinical importance of antiphospholipid antibodies. Adv Immunol 1991, 49:193-280.
21. Petri M. Hopkins Lupus Pregnancy Center: 1987 to 1996. Rheum Dis Clin North Am 1997, 23(1):1-13.
22. Reece E.A., Coustan D.R., Gabbe S.G. Diabetes in Women: Adolescence, Pregnancy and Menopause 2004, Lippincott Williams & Wilkins, Philadelphia, PA. 3rd ed.
23. Mackie A.D., Doddridge M.C., Gamsu H.R., Brudenell J.M., Nicolaides K.H., Drury P.L. Outcome of pregnancy in patients with insulin-dependent diabetes mellitus and nephropathy with moderate renal impairment. Diabet Med 1996, 13(1):90-96.
24. Combs C.A., Rosenn B., Kitzmiller J.L., Khoury J.C., Wheeler B.C., Miodovnik M. Early-pregnancy proteinuria in diabetes related to preeclampsia. Obstet Gynecol 1993, 82(5):802-807.
25. Reece E.A., Leguizamon G., Homko C. Pregnancy performance and outcomes associated with diabetic nephropathy. Am J Perinatol 1998, 15(7):413-421.
26. Hod M., van Dijk D.J., Karp M., et al. Diabetic nephropathy and pregnancy: the effect of ACE inhibitors prior to pregnancy on fetomaternal outcome. Nephrol Dial Transplant 1995, 10(12):2328-2333.
27. U.S.Renal Data System USRDS 2010 Annual Data Report: Atlas of Chronic Kidney Disease and End-Stage Renal Disease in the United States 2010, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD.
28. Kitiyakara C., Kopp J.B., Eggers P. Trends in the epidemiology of focal segmental glomerulosclerosis. Semin Nephrol 2003, 23(2):172-182.
29. D'Agati V.D., Kaskel F.J., Falk R.J. Focal segmental glomerulosclerosis. N Engl J Med 2011, 365(25):2398-2411.
30. Churchill D., Beevers G.D., Meher S., Rhodes C. Diuretics for preventing pre-eclampsia. Cochrane Database Syst Rev 2007, 1:CD004451.
31. Report of the National High Blood Pressure Education Program Working Group on High Blood Pressure in Pregnancy. Am J Obstet Gynecol 2000, 183(1):S1-S22.
32. Banfi G., Moriggi M., Sabadini E., Fellin G., D'Amico G., Ponticelli C. The impact of prolonged immunosuppression on the outcome of idiopathic focal-segmental glomerulosclerosis with nephrotic syndrome in adults. A collaborative retrospective study. Clin Nephrol 1991, 36(2):53-59.
33. van Runnard Heimel P.J., Schobben A.F., Huisjes A.J., Franx A., Bruinse H.W. The transplacental passage of prednisolone in pregnancies complicated by early-onset HELLP syndrome. Placenta 2005, 26(10):842-845.
34. Haas M., Meehan S.M., Karrison T.G., Spargo B.H. Changing etiologies of unexplained adult nephrotic syndrome: a comparison of renal biopsy findings from 1976-1979 and 1995-1997. Am J Kidney Dis 1997, 30(5):621-631.
35. Leisti S., Koskimies O. Risk of relapse in steroid-sensitive nephrotic syndrome: effect of stage of post-prednisone adrenocortical suppression. J Pediatr 1983, 103(4):553-557.
36. Beck L.H., Bonegio R.G., Lambeau G., et al. M-type phospholipase A2 receptor as target antigen in idiopathic membranous nephropathy. N Engl J Med 2009, 361(1):11-21.
37. Limardo M., Imbasciati E., Ravani P., et al. Pregnancy and progression of IgA nephropathy: results of an Italian multicenter study. Am J Kidney Dis 2010, 56(3):506-512.
38. Oh H.J., Han S.H., Yoo D.E., et al. Reduced pre-pregnancy proteinuria is associated with improving postnatal maternal renal outcomes in IgA nephropathy women. Clin Nephrol 2011, 76(6):447-454.
39. Abe S. The influence of pregnancy on the long-term renal prognosis of IgA nephropathy. Clin Nephrol 1994, 41(2):61-64.
40. Seo P. Pregnancy and vasculitis. Rheum Dis Clin North Am 2007, 33(2):299-317.
41. Suri V., Aggarwal N., Keepanasseril A., Chopra S., Vijayvergiya R., Jain S. Pregnancy and Takayasu arteritis: a single centre experience from North India. J Obstet Gynaecol Res 2010, 36(3):519-524.
42. Koukoura O., Mantas N., Linardakis H., Hajiioannou J., Sifakis S. Successful term pregnancy in a patient with Wegener's granulomatosis: case report and literature review. Fertil Steril 2008, 89(2). 457.e1-e5.
43. Bansal P.J., Tobin M.C. Neonatal microscopic polyangiitis secondary to transfer of maternal myeloperoxidase-antineutrophil cytoplasmic antibody resulting in neonatal pulmonary hemorrhage and renal involvement. Ann Allergy Asthma Immunol 2004, 93(4):398-401.
44. Fakhouri F., Roumenina L., Provot F., et al. Pregnancy-associated hemolytic uremic syndrome revisited in the era of complement gene mutations. J Am Soc Nephrol 2010, 21(5):859-867.
45. Steen V.D. Pregnancy in women with systemic sclerosis. Obstet Gynecol 1999, 94(1):15-20.
46. Mouthon L., Berezne A., Bussone G., Noel L.H., Villiger P.M., Guillevin L. Scleroderma renal crisis: a rare but severe complication of systemic sclerosis. Clin Rev Allergy Immunol 2011, 40(2):84-91.
47. Piccoli G.B., Daidola G., Attini R., et al. Kidney biopsy in pregnancy: evidence for counselling? A systematic narrative review. BJOG 2013, 120(4):412-427.
48. Lindheimer M.D., Davison J.M. Renal biopsy during pregnancy: 'to b. . . or not to b. . .?'. BJOG 1987, 94(10):932-934.
49. Cooper W.O., Hernandez-Diaz S., Arbogast P.G., et al. Major congenital malformations after first-trimester exposure to ACE inhibitors. N Engl J Med 2006, 354(23):2443-2451.
50. Brown C.M., Garovic V.D. Mechanisms and management of hypertension in pregnant women. Curr Hypertens Rep 2011, 13(5):338-346.
51. Stevenson R.E., Burton O.M., Ferlauto G.J., Taylor H.A. Hazards of oral anticoagulants during pregnancy. JAMA 1980, 243(15):1549-1551.
52. Pincus K.J., Hynicka L.M. Prophylaxis of thromboembolic events in patients with nephrotic syndrome. Ann Pharmacother 2013, 47(5):725-734.
53. Levine R.J., Maynard S.E., Qian C., et al. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 2004, 350(7):672-683. [see comment].
54. Eremina V., Sood M., Haigh J., et al. Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest 2003, 111(5):707-716.
55. Eremina V., Jefferson J.A., Kowalewska J., et al. VEGF inhibition and renal thrombotic microangiopathy. N Engl J Med 2008, 358(11):1129-1136.
56. Garovic V.D., Wagner S.J., Turner S.T., et al. Urinary podocyte excretion as a marker for preeclampsia. Am J Obstet Gynecol 2007, 196(4). [see comment], 320.e1-e7.
57. Aita K., Etoh M., Hamada H., et al. Acute and transient podocyte loss and proteinuria in preeclampsia. Nephron Clin Pract 2009, 112(2):c65-c70.
58. Craici I.M., Wagner S.J., Bailey K.R., et al. Podocyturia predates proteinuria and clinical features of preeclampsia: longitudinal prospective study. Hypertension 2013, 61(6):c65-c70.
59. Garovic V.D., Bailey K.R., Boerwinkle E., et al. Hypertension in pregnancy as a risk factor for cardiovascular disease later in life. J Hypertens 2010, 28(4):826-833.
60. Bar J., Kaplan B., Wittenberg C., et al. Microalbuminuria after pregnancy complicated by pre-eclampsia. Nephrol Dial Transplant 1999, 14(5):1129-1132.
61. Vikse B.E., Irgens L.M., Bostad L., Iversen B.M. Adverse perinatal outcome and later kidney biopsy in the mother. J Am Soc Nephrol 2006, 17(3):837-845.
62. Vikse B.E., Irgens L.M., Leivestad T., Skjaerven R., Iversen B.M. Preeclampsia and the risk of end-stage renal disease. N Engl J Med 2008, 359(8):800-809.
63. Wang I.K., Muo C.H., Chang Y.C., et al. Association between hypertensive disorders during pregnancy and end-stage renal disease: a population-based study. CMAJ 2013, 185(3):207-213.
64. European Best Practice Guidelines for renal transplantation. Section IV: Long-term management of the transplant recipient. IV.10. Pregnancy in renal transplant recipients. Nephrol Dial Transplant 2002, 17(suppl 4):50-55.
65. Fraser F.C., Fainstat T.D. Production of congenital defects in the off-spring of pregnant mice treated with cortisone; progress report. Pediatrics 1951, 8(4):527-533.
66. Fraser F.C., Sajoo A. Teratogenic potential of corticosteroids in humans. Teratology 1995, 51(1):45-46.
67. Hviid A., Molgaard-Nielsen D. Corticosteroid use during pregnancy and risk of orofacial clefts. CMAJ 2011, 183(7):796-804.
68. Clowse M.E., Magder L., Witter F., Petri M. Hydroxychloroquine in lupus pregnancy. Arthritis Rheum 2006, 54(11):3640-3647.
69. Costedoat-Chalumeau N., Amoura Z., Huong D.L., Lechat P., Piette J.C. Safety of hydroxychloroquine in pregnant patients with connective tissue diseases. Review of the literature. Autoimmun Rev 2005, 4(2):111-115.
70. Levy R.A., Vilela V.S., Cataldo M.J., et al. Hydroxychloroquine (HCQ) in lupus pregnancy: double-blind and placebo-controlled study. Lupus 2001, 10(6):401-404.
71. Cortes-Hernandez J., Ordi-Ros J., Paredes F., Casellas M., Castillo F., Vilardell-Tarres M. Clinical predictors of fetal and maternal outcome in systemic lupus erythematosus: a prospective study of 103 pregnancies. Rheumatology (Oxford) 2002, 41(6):643-650.
72. A randomized study of the effect of withdrawing hydroxychloroquine sulfate in systemic lupus erythematosus. The Canadian Hydroxychloroquine Study Group. N Engl J Med 1991, 324(3):150-154.
73. Clowse M.E. Lupus activity in pregnancy. Rheum Dis Clin North Am 2007, 33(2):237-252. v.
74. Cleary B.J., Kallen B. Early pregnancy azathioprine use and pregnancy outcomes. Birth Defects Res A Clin Mol Teratol 2009, 85(7):647-654.
75. Anderka M.T., Lin A.E., Abuelo D.N., Mitchell A.A., Rasmussen S.A. Reviewing the evidence for mycophenolate mofetil as a new teratogen: case report and review of the literature. Am J Med Genet A 2009, 149A(6):1241-1248.
76. El Sebaaly Z., Charpentier B., Snanoudj R. Fetal malformations associated with mycophenolate mofetil for lupus nephritis. Nephrol Dial Transplant 2007, 22(9):2722.
77. Ostensen M., Khamashta M., Lockshin M., et al. Anti-inflammatory and immunosuppressive drugs and reproduction. Arthritis Res Ther 2006, 8(3):209.
78. Chen W., Tang X., Liu Q., et al. Short-term outcomes of induction therapy with tacrolimus versus cyclophosphamide for active lupus nephritis: a multicenter randomized clinical trial. Am J Kidney Dis 2011, 57(2):235-244.
79. Coscia L.A., Constantinescu S., Moritz M.J., et al. Report from the National Transplantation Pregnancy Registry (NTPR): outcomes of pregnancy after transplantation. Clin Transpl 2010, 65-85.
80. Hahn K.M., Johnson P.H., Gordon N., et al. Treatment of pregnant breast cancer patients and outcomes of children exposed to chemotherapy in utero. Cancer 2006, 107(6):1219-1226.
81. Moroni G., Ponticelli C. Pregnancy after lupus nephritis. Lupus 2005, 14(1):89-94.
82. Vaidyanathan A., McKeever K., Anand B., Eppler S., Weinbauer G.F., Beyer J.C. Developmental immunotoxicology assessment of rituximab in cynomolgus monkeys. Toxicol Sci 2011, 119(1):116-125.