The amazing odontoblast: Activity, autophagy, and aging

Journal of Dental Research

Volumn 92, Issue 9, 2013, Pages 765-772

  Couve, E ^a   Osorio, R ^a   Schmachtenberg, O ^a  

^a UNIVERSIDAD DE VALPARAÍSO   (Chile)

Author keywords

dentin; human dental pulp; lipofuscin; sensory system

Indexed keywords

LIPOFUSCIN;

AUTOPHAGY; CELL AGING; CYTOLOGY; DENTIN; HUMAN; HUMAN DENTAL PULP; INNERVATION; ODONTOBLAST; PHYSIOLOGY; REVIEW; SENSORY RECEPTOR; SENSORY SYSTEM; TOOTH PULP;

DENTIN; HUMAN DENTAL PULP; LIPOFUSCIN; SENSORY SYSTEM;

AUTOPHAGY; CELL AGING; DENTAL PULP; DENTIN; HUMANS; ODONTOBLASTS; SENSORY RECEPTOR CELLS;

EID: 84882750989     PISSN: 00220345     EISSN: 15440591     Source Type: Journal    
DOI: 10.1177/0022034513495874     Document Type: Review

References (62)

1. About I, Proust JP, Raffo S, Mitsiadis TA, Franquin JC. In vivo and in vitro expression of connexin 43 in human teeth. Connect Tissue Res. 2002 ; 43: 232-237
2. Ashrafi G, Schwarz TL. The pathways of mitophagy for quality control and clearance of mitochondria. Cell Death Differ. 2013 ; 20: 31-42
3. Balic A, Mina M. Identification of secretory odontoblasts using DMP1-GFP transgenic mice. Bone. 2011 ; 48: 927-937
4. Benmerah A. The ciliary pocket. Curr Opin Cell Biol. 2013 ; 25: 78-84
5. Bernick S. Effect of aging on the nerve supply to human teeth. J Dent Res. 1967 ; 46: 694-699
6. Byers MR, Taylor PE. Effect of sensory denervation on the response of rat molar pulp to exposure injury. J Dent Res. 1993 ; 72: 613-618
7. Byers MR, Westenbroek RE. Odontoblasts in developing, mature and ageing rat teeth have multiple phenotypes that variably express all nine voltage-gated sodium channels. Arch Oral Biol. 2011 ; 56: 1199-1220
8. Byers MR, Suzuki H, Maeda T. Dental neuroplasticity, neuro-pulpal interactions, and nerve regeneration. Microsc Res Tech. 2003 ; 60: 503-515
9. Caviedes-Bucheli J, Moreno JO, Ardila-Pinto J, Del Toro-Carreno HR, Saltarin-Quintero H, Sierra-Tapias CL, et al. The effect of orthodontic forces on calcitonin gene-related peptide expression in human dental pulp. J Endod. 2011 ; 37: 934-937
10. Chai Y, Jiang X, Ito Y, Bringas P, Han J, Rowitch DH, et al. Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development. 2000 ; 127: 1671-1679
11. Choi SJ, Song IS, Feng JQ, Gao T, Haruyama N, Gautam P, et al. Mutant DLX 3 disrupts odontoblast polarization and dentin formation. Dev Biol. 2010 ; 344: 682-692
12. Couve E. Ultrastructural changes during the life cycle of human odontoblasts. Arch Oral Biol. 1986 ; 31: 643-651
13. Couve E, Schmachtenberg O. Autophagic activity and aging in human odontoblasts. J Dent Res. 2011 ; 90: 523-528
14. Couve E, Osorio R, Schmachtenberg O. Mitochondrial autophagy and lipofuscin accumulation in aging odontoblasts. J Dent Res. 2012 ; 91: 696-701
15. Cuervo AM, Bergamini E, Brunk UT, Droge W, Ffrench M, Terman A. Autophagy and aging: the importance of maintaining "clean" cells. Autophagy. 2005 ; 1: 131-140
16. Dassule HR, Lewis P, Bei M, Maas R, McMahon AP. Sonic hedgehog regulates growth and morphogenesis of the tooth. Development. 2000 ; 127: 4775-4785
17. Diogenes A, Ferraz CC, Akopian AN, Henry MA, Hargreaves KM. LPS sensitizes TRPV1 via activation of TLR4 in trigeminal sensory neurons. J Dent Res. 2011 ; 90: 759-764
18. Durand SH, Flacher V, Romeas A, Carrouel F, Colomb E, Vincent C, et al. Lipoteichoic acid increases TLR and functional chemokine expression while reducing dentin formation in in vitro differentiated human odontoblasts. J Immunol. 2006 ; 176: 2880-2887
19. Duverger O, Zah A, Isaac J, Sun HW, Bartels AK, Lian JB, et al. Neural crest deletion of Dlx3 leads to major dentin defects through down-regulation of Dspp. J Biol Chem. 2012 ; 287: 12230-12240
20. Farahani RM, Simonian M, Hunter N. Blueprint of an ancestral neurosensory organ revealed in glial networks in human dental pulp. J Comp Neurol. 2011 ; 519: 3306-3326
21. Farges JC, Carrouel F, Keller JF, Baudouin C, Msika P, Bleicher F, et al. Cytokine production by human odontoblast-like cells upon Toll-like receptor-2 engagement. Immunobiology. 2011 ; 216: 513-517
22. Fried K, Nosrat C, Lillesaar C, Hildebrand C. Molecular signaling and pulpal nerve development. Crit Rev Oral Biol Med. 2000 ; 11: 318-332
23. Goldberg M, Kulkarni AB, Young M, Boskey A. Dentin: structure, composition and mineralization. Front Biosci (Elite Ed). 2011 ; 3: 711-735
24. Hahn CL, Liewehr FR. Innate immune responses of the dental pulp to caries. J Endod. 2007 ; 33: 643-651
25. Hall BK, Gillis JA. Incremental evolution of the neural crest, neural crest cells and neural crest-derived skeletal tissues. J Anat. 2013 ; 222: 19-31
26. He C, Klionsky DJ. Regulation mechanisms and signaling pathways of autophagy. Annu Rev Genet. 2009 ; 43: 67-93
27. Ikeda H, Suda H. Sensory experiences in relation to pulpal nerve activation of human teeth in different age groups. Arch Oral Biol. 2003 ; 48: 835-841
28. Ikeda H, Suda H. Odontoblastic syncytium through electrical coupling in the human dental pulp. J Dent Res. 2013 ; 92: 371-375
29. Kawasaki K, Weiss KM. SCPP gene evolution and the dental mineralization continuum. J Dent Res. 2008 ; 87: 520-531
30. Keller JF, Carrouel F, Colomb E, Durand SH, Baudouin C, Msika P, et al. Toll-like receptor 2 activation by lipoteichoic acid induces differential production of pro-inflammatory cytokines in human odontoblasts, dental pulp fibroblasts and immature dendritic cells. Immunobiology. 2010 ; 215: 53-59
31. Kim TH, Lee JY, Baek JA, Lee JC, Yang X, Taketo MM, et al. Constitutive stabilization of ss-catenin in the dental mesenchyme leads to excessive dentin and cementum formation. Biochem Biophys Res Commun. 2011 ; 412: 549-555
32. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 ; 8: 445-544
33. Koussoulakou DS, Margaritis LH, Koussoulakos SL. A curriculum vitae of teeth: evolution, generation, regeneration. Int J Biol Sci. 2009 ; 5: 226-243
34. Larmas MA, Sándor GK. Solid nomenclature: the bedrock of science. Similarities and dissimilarities in phenomena and cells of tooth and bone ontogeny. Anat Rec (Hoboken). 2013 ; 296: 564-567
35. Lee YH, Kim GE, Cho HJ, Yu MK, Bhattarai G, Lee NH, et al. Aging of in vitro pulp illustrates change of inflammation and dentinogenesis. J Endod. 2013 ; 39: 340-345
36. Li L, Zhu YQ, Jiang L, Peng W. Increased autophagic activity in senescent human dental pulp cells. Int Endod J. 2012 ; 45: 1074-1079
37. Luukko K, Kvinnsland IH, Kettunen P. Tissue interactions in the regulation of axon pathfinding during tooth morphogenesis. Dev Dyn. 2005 ; 234: 482-488
38. Magloire H, Couble ML, Romeas A, Bleicher F. Odontoblast primary cilia: facts and hypotheses. Cell Biol Int. 2004 ; 28: 93-99
39. Magloire H, Maurin JC, Couble ML, Shibukawa Y, Tsumura M, Thivichon-Prince B, et al. Topical review. Dental pain and odontoblasts: facts and hypotheses. J Orofac Pain. 2010 ; 24: 335-349
40. Maurin JC, Delorme G, Machuca-Gayet I, Couble ML, Magloire H, Jurdic P, et al. Odontoblast expression of semaphorin 7A during innervation of human dentin. Matrix Biol. 2005 ; 24: 232-238
41. Mizushima N, Levine B, Cuervo AM, Klionsky DJ. Autophagy fights disease through cellular self-digestion. Nature. 2008 ; 451: 1069-1075
42. Moe K, Sijaona A, Shrestha A, Kettunen P, Taniguchi M, Luukko K. Semaphorin 3A controls timing and patterning of the dental pulp innervation. Differentiation. 2012 ; 84: 371-379
43. Mornstad H, Pfeiffer H, Yoon C, Teivens A. Demonstration and semi-quantification of mtDNA from human dentine and its relation to age. Int J Legal Med. 1999 ; 112: 98-100
44. Muramatsu T, Hamano H, Ogami K, Ohta K, Inoue T, Shimono M. Reduction of connexin 43 expression in aged human dental pulp. Int Endod J. 2004 ; 37: 814-818
45. Murray PE, Stanley HR, Matthews JB, Sloan AJ, Smith AJ. Age-related odontometric changes of human teeth. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2002 ; 93: 474-482
46. Ohazama A, Haycraft CJ, Seppala M, Blackburn J, Ghafoor S, Cobourne M, et al. Primary cilia regulate Shh activity in the control of molar tooth number. Development. 2009 ; 136: 897-903
47. Rezzani R, Stacchiotti A, Rodella LF. Morphological and biochemical studies on aging and autophagy. Ageing Res Rev. 2012 ; 11: 10-31
48. Rubinsztein DC, Marino G, Kroemer G. Autophagy and aging. Cell. 2011 ; 146: 682-695
49. Sakurai K, Okiji T, Suda H. Co-increase of nerve fibers and HLA-DR- and/or factor-XIIIa-expressing dendritic cells in dentinal caries-affected regions of the human dental pulp: an immunohistochemical study. J Dent Res. 1999 ; 78: 1596-1608
50. Shintani T, Klionsky DJ. Autophagy in health and disease: a double-edged sword. Science. 2004 ; 306: 990-995
51. Simon S, Smith AJ, Lumley PJ, Berdal A, Smith G, Finney S, et al. Molecular characterization of young and mature odontoblasts. Bone. 2009 ; 45: 693-703
52. Singla V, Reiter JF. The primary cilium as the cell's antenna: signaling at a sensory organelle. Science. 2006 ; 313: 629-633
53. Smith AJ, Cassidy N, Perry H, Bègue-Kirn C, Ruch JV, Lesot H. Reactionary dentinogenesis. Int J Dev Biol. 1995 ; 39: 273-280
54. Smith MM, Sansom IJ Development, function and evolution of teeth. Teaford MF Smith MM Ferguson MW, ed. Cambridge, UK: Cambridge University Press ; 2000: 65-81.
55. Terman A, Kurz T, Navratil M, Arriaga EA, Brunk UT. Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging. Antioxid Redox Signal. 2010 ; 12: 503-535
56. Thivichon-Prince B, Couble ML, Giamarchi A, Delmas P, Franco B, Romio L, et al. Primary cilia of odontoblasts: possible role in molar morphogenesis. J Dent Res. 2009 ; 88: 910-915
57. Tsakos G. Inequalities in oral health of the elderly: rising to the public health challenge?. J Dent Res. 2011 ; 90: 689-690
58. Veerayutthwilai O, Byers MR, Pham TT, Darveau RP, Dale BA. Differential regulation of immune responses by odontoblasts. Oral Microbiol Immunol. 2007 ; 22: 5-13
59. Wadachi R, Hargreaves KM. Trigeminal nociceptors express TLR-4 and CD14: a mechanism for pain due to infection. J Dent Res. 2006 ; 85: 49-53
60. Weinstock M, Leblond CP. Synthesis, migration, and release of precursor collagen by odontoblasts as visualized by radioautography after (3H)proline administration. J Cell Biol. 1974 ; 60: 92-127
61. Yang JW, Zhu LX, Yuan GH, Chen YX, Zhang L, Chen Z. Autophagy appears during the development of the mouse lower first molar. Histochem Cell Biol. 2013 ; 139: 109-118
62. Yoshiba K, Yoshiba N, Iwaku M. Class II antigen-presenting dendritic cell and nerve fiber responses to cavities, caries, or caries treatment in human teeth. J Dent Res. 2003 ; 82: 422-427