Hypermethylation of the DNA mismatch repair gene hMLH1 and its association with lymph node metastasis and T1799A BRAF mutation in patients with papillary thyroid cancer

Cancer

Volumn 113, Issue 2, 2008, Pages 247-255

  Guan, Haixia ^a,b   Ji, Meiju ^a   Hou, Peng ^a   Liu, Zhi ^a   Wang, Cuifang ^c   Shan, Zhongyan ^b   Teng, Weiping ^b   Xing, Michael Mingzhao ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CHINA MEDICAL UNIVERSITY   (China)

^c Shenyang No 8 People's Hospital   (China)

Author keywords

BRAF mutation; DNA repair genes; hMLH1; Methylation; Thyroid cancer

Indexed keywords

B RAF KINASE; PROTEIN MLH1;

ADULT; ARTICLE; CANCER GENETICS; CLINICAL ARTICLE; DNA METHYLATION; FEMALE; GENE; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH NODE METASTASIS; MALE; MISMATCH REPAIR; OGG1 GENE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; THYROID PAPILLARY CARCINOMA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOSINE; CARCINOMA, PAPILLARY; CELL LINE, TUMOR; DNA METHYLATION; DNA MISMATCH REPAIR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LYMPHATIC METASTASIS; MAP KINASE SIGNALING SYSTEM; MUTATION; NUCLEAR PROTEINS; PROTO-ONCOGENE PROTEINS B-RAF; THYMIDINE; THYROID NEOPLASMS;

EID: 48249084096     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.23548     Document Type: Article

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