Induction of retinal ganglion-like cells from fibroblasts by adenoviral gene delivery

Neuroscience

Volumn 250, Issue , 2013, Pages 381-393

  Meng, F ^a   Wang, X ^a   Gu, P ^b   Wang, Z ^a   Guo, W ^a  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Adenovirus; Fibroblast; Reprogramming; Retinal ganglion cell

Indexed keywords

ADENOVIRUS VECTOR; GENOMIC DNA; LENTIVIRUS VECTOR; NEUROGENIN 2; TRANSCRIPTION FACTOR MASH1; TRANSCRIPTION FACTOR POU4F2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASCL1 GENE; BRN3B GENE; CELL TRANSFORMATION; CONTROLLED STUDY; EMBRYO; FIBROBLAST; GENETIC TRANSDUCTION; MOUSE; NERVE CELL DIFFERENTIATION; NERVE FUNCTION; NGN2 GENE; NONHUMAN; NUCLEAR REPROGRAMMING; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA DEGENERATION; RETINA GANGLION CELL; VIRAL GENE DELIVERY SYSTEM;

4-(2-HYDROXYETHYL)-1-PIPERAZINEETHANESULFONIC ACID; AB(2)N-INDUCED NEURONS; AB(2)N-INS; ADENOVIRUS; EAR TIP FIBROBLAST; EGTA; EMBRYONIC STEM CELLS; ESCS; ETF; ETHYLENE GLYCOL TETRAACETIC ACID; FIBROBLAST; HEPES; INDUCED PLURIPOTENT STEM CELL; INDUCED RETINAL GANGLION-LIKE CELL; IPSC; IRG-LIKE CELL; MEF; MOI; MOUSE EMBRYONIC FIBROBLAST; MULTIPLICITIES OF INFECTION; PCR; POLYMERASE CHAIN REACTION; REPROGRAMMING; RETINAL GANGLION CELL; RGC;

ADENOVIRIDAE; ANIMALS; ELECTROPHYSIOLOGICAL PROCESSES; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; MICE; POLYMERASE CHAIN REACTION; PRIMARY CELL CULTURE; RETINAL GANGLION CELLS; TRANSCRIPTION FACTORS;

EID: 84882735279     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2013.07.001     Document Type: Article

References (43)

1. Addis R.C., Hsu F.C., Wright R.L., Dichter M.A., Coulter D.A., Gearhart J.D. Efficient conversion of astrocytes to functional midbrain dopaminergic neurons using a single polycistronic vector. PLoS ONE 2011, 6:e28719.
2. Brown N.L., Kanekar S., Vetter M.L., Tucker P.K., Gemza D.L., Glaser T. Math5 encodes a murine basic helix-loop-helix transcription factor expressed during early stages of retinal neurogenesis. Development 1998, 125:4821-4833.
3. Caiazzo M., Dell'Anno M.T., Dvoretskova E., Lazarevic D., Taverna S., Leo D., Sotnikova T.D., Menegon A., Roncaglia P., Colciago G., Russo G., Carninci P., Pezzoli G., Gainetdinov R.R., Gustincich S., Dityatev A., Broccoli V. Direct generation of functional dopaminergic neurons from mouse and human fibroblasts. Nature 2011, 476:224-227.
4. Campbell K.H., McWhir J., Ritchie W.A., Wilmut I. Sheep cloned by nuclear transfer from a cultured cell line. Nature 1996, 380:64-66.
5. Chambers S.M., Studer L. Cell fate plug and play: direct reprogramming and induced pluripotency. Cell 2011, 145:827-830.
6. Chen M., Chen Q., Sun X., Shen W., Liu B., Zhong X., Leng Y., Li C., Zhang W., Chai F., Huang B., Gao Q., Xiang A.P., Zhuo Y., Ge J. Generation of retinal ganglion-like cells from reprogrammed mouse fibroblasts. Invest Ophthalmol Vis Sci 2010, 51:5970-5978.
7. Cowan C.A., Atienza J., Melton D.A., Eggan K. Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells. Science 2005, 309:1369-1373.
8. Grealish S., Jakobsson J., Parmar M. Lineage reprogramming: a shortcut to generating functional neurons from fibroblasts. Cell Cycle 2011, 10:3421-3422.
9. Gurdon J.B., Elsdale T.R., Fischberg M. Sexually mature individuals of Xenopus laevis from the transplantation of single somatic nuclei. Nature 1958, 182:64-65.
10. Hirami Y., Osakada F., Takahashi K., Okita K., Yamanaka S., Ikeda H., Yoshimura N., Takahashi M. Generation of retinal cells from mouse and human induced pluripotent stem cells. Neurosci Lett 2009, 458:126-131.
11. Huang P., He Z., Ji S., Sun H., Xiang D., Liu C., Hu Y., Wang X., Hui L. Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors. Nature 2011, 475:386-389.
12. Ieda M., Fu J.D., Delgado-Olguin P., Vedantham V., Hayashi Y., Bruneau B.G., Srivastava D. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 2010, 142:375-386.
13. Jagatha B., Divya M.S., Sanalkumar R., Indulekha C.L., Vidyanand S., Divya T.S., Das A.V., James J. In vitro differentiation of retinal ganglion-like cells from embryonic stem cell derived neural progenitors. Biochem Biophys Res Commun 2009, 380:230-235.
14. Kay J.N., Finger-Baier K.C., Roeser T., Staub W., Baier H. Retinal ganglion cell genesis requires lakritz, a zebrafish atonal homolog. Neuron 2001, 30:725-736.
15. Kim J., Efe J.A., Zhu S., Talantova M., Yuan X., Wang S., Lipton S.A., Zhang K., Ding S. Direct reprogramming of mouse fibroblasts to neural progenitors. Proc Natl Acad Sci U S A 2011, 108:7838-7843.
16. Kim J., Su S.C., Wang H., Cheng A.W., Cassady J.P., Lodato M.A., Lengner C.J., Chung C.Y., Dawlaty M.M., Tsai L.H., Jaenisch R. Functional integration of dopaminergic neurons directly converted from mouse fibroblasts. Cell Stem Cell 2011, 9:413-419.
17. Kim K.S. Converting human skin cells to neurons: a new tool to study and treat brain disorders?. Cell Stem Cell 2011, 9:179-181.
18. Kingman S. Glaucoma is second leading cause of blindness globally. Bull World Health Organ 2004, 82:887-888.
19. Lamba D.A., Karl M.O., Ware C.B., Reh T.A. Efficient generation of retinal progenitor cells from human embryonic stem cells. Proc Natl Acad Sci U S A 2006, 103:12769-12774.
20. Liu X., Li F., Stubblefield E.A., Blanchard B., Richards T.L., Larson G.A., He Y., Huang Q., Tan A.C., Zhang D., Benke T.A., Sladek J.R., Zahniser N.R., Li C.Y. Direct reprogramming of human fibroblasts into dopaminergic neuron-like cells. Cell Res 2012, 22:321-332.
21. Lu J., Liu H., Huang C.T., Chen H., Du Z., Liu Y., Sherafat M.A., Zhang S.C. Generation of integration-free and region-specific neural progenitors from primate fibroblasts. Cell Rep 2013, 3:1580-1591.
22. Matter-Sadzinski L., Puzianowska-Kuznicka M., Hernandez J., Ballivet M., Matter J.M. A bHLH transcriptional network regulating the specification of retinal ganglion cells. Development 2005, 132:3907-3921.
23. Meng F., Chen S., Miao Q., Zhou K., Lao Q., Zhang X., Guo W., Jiao J. Induction of fibroblasts to neurons through adenoviral gene delivery. Cell Res 2012, 22:436-440.
24. Najm F.J., Lager A.M., Zaremba A., Wyatt K., Caprariello A.V., Factor D.C., Karl R.T., Maeda T., Miller R.H., Tesar P.J. Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells. Nat Biotechnol 2013, 31:426-433.
25. Parameswaran S., Balasubramanian S., Babai N., Qiu F., Eudy J.D., Thoreson W.B., Ahmad I. Induced pluripotent stem cells generate both retinal ganglion cells and photoreceptors: therapeutic implications in degenerative changes in glaucoma and age-related macular degeneration. Stem Cells 2010, 28:695-703.
26. Pera M.F. Stem cells: the dark side of induced pluripotency. Nature 2011, 471:46-47.
27. Pfisterer U., Kirkeby A., Torper O., Wood J., Nelander J., Dufour A., Bjorklund A., Lindvall O., Jakobsson J., Parmar M. Direct conversion of human fibroblasts to dopaminergic neurons. Proc Natl Acad Sci U S A 2011, 108:10343-10348.
28. Qiang L., Fujita R., Yamashita T., Angulo S., Rhinn H., Rhee D., Doege C., Chau L., Aubry L., Vanti W.B., Moreno H., Abeliovich A. Directed conversion of Alzheimer's disease patient skin fibroblasts into functional neurons. Cell 2011, 146:359-371.
29. Sheng C., Zheng Q., Wu J., Xu Z., Wang L., Li W., Zhang H., Zhao X.Y., Liu L., Wang Z., Guo C., Wu H.J., Liu Z., He S., Wang X.J., Chen Z., Zhou Q. Direct reprogramming of sertoli cells into multipotent neural stem cells by defined factors. Cell Res 2012, 22:208-218.
30. Son E.Y., Ichida J.K., Wainger B.J., Toma J.S., Rafuse V.F., Woolf C.J., Eggan K. Conversion of mouse and human fibroblasts into functional spinal motor neurons. Cell Stem Cell 2011, 9:205-218.
31. Stadtfeld M., Nagaya M., Utikal J., Weir G., Hochedlinger K. Induced pluripotent stem cells generated without viral integration. Science 2008, 322:945-949.
32. Szabo E., Rampalli S., Risueno R.M., Schnerch A., Mitchell R., Fiebig-Comyn A., Levadoux-Martin M., Bhatia M. Direct conversion of human fibroblasts to multilineage blood progenitors. Nature 2010, 468:521-526.
33. Tada M., Takahama Y., Abe K., Nakatsuji N., Tada T. Nuclear reprogramming of somatic cells by in vitro hybridization with ES cells. Curr Biol 2001, 11:1553-1558.
34. Takahashi K., Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006, 126:663-676.
35. Thier M., Worsdorfer P., Lakes Y.B., Gorris R., Herms S., Opitz T., Seiferling D., Quandel T., Hoffmann P., Nothen M.M., Brustle O., Edenhofer F. Direct conversion of fibroblasts into stably expandable neural stem cells. Cell Stem Cell 2012, 10:473-479.
36. Vierbuchen T., Ostermeier A., Pang Z.P., Kokubu Y., Sudhof T.C., Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 2010, 463:1035-1041.
37. Wang S.W., Kim B.S., Ding K., Wang H., Sun D., Johnson R.L., Klein W.H., Gan L. Requirement for math5 in the development of retinal ganglion cells. Genes Dev 2001, 15:24-29.
38. Wang L., Huang W., Su H., Xue Y., Su Z., Liao B., Wang H., Bao X., Qin D., He J., Wu W., So K.F., Pan G., Pei D. Generation of integration-free neural progenitor cells from cells in human urine. Nat Methods 2013, 10:84-89.
39. Weintraub H., Tapscott S.J., Davis R.L., Thayer M.J., Adam M.A., Lassar A.B., Miller A.D. Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD. Proc Natl Acad Sci U S A 1989, 86:5434-5438.
40. Xue Y., Ouyang K., Huang J., Zhou Y., Ouyang H., Li H., Wang G., Wu Q., Wei C., Bi Y., Jiang L., Cai Z., Sun H., Zhang K., Zhang Y., Chen J., Fu X.D. Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits. Cell 2013, 152:82-96.
41. Yang Z., Ding K., Pan L., Deng M., Gan L. Math5 determines the competence state of retinal ganglion cell progenitors. Dev Biol 2003, 264:240-254.
42. Yoo A.S., Sun A.X., Li L., Shcheglovitov A., Portmann T., Li Y., Lee-Messer C., Dolmetsch R.E., Tsien R.W., Crabtree G.R. MicroRNA-mediated conversion of human fibroblasts to neurons. Nature 2011, 476:228-231.
43. Zhou Q., Melton D.A. Extreme makeover: converting one cell into another. Cell Stem Cell 2008, 3:382-388.