-
1
-
-
33747104564
-
Substrate specificity of lipoprotein lipase and endothelial lipase: studies of lid chimeras
-
Griffon N, Budreck EC, Long CJ, Broedl UC, Marchadier DH, et al. (2006) Substrate specificity of lipoprotein lipase and endothelial lipase: studies of lid chimeras. J Lipid Res 47: 1803-1811.
-
(2006)
J Lipid Res
, vol.47
, pp. 1803-1811
-
-
Griffon, N.1
Budreck, E.C.2
Long, C.J.3
Broedl, U.C.4
Marchadier, D.H.5
-
2
-
-
0029920693
-
Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis
-
Goldberg IJ, (1996) Lipoprotein lipase and lipolysis: central roles in lipoprotein metabolism and atherogenesis. J Lipid Res 37: 693-707.
-
(1996)
J Lipid Res
, vol.37
, pp. 693-707
-
-
Goldberg, I.J.1
-
3
-
-
0026323335
-
Domain exchange: characterization of a chimeric lipase of hepatic lipase and lipoprotein lipase
-
Wong H, Davis RC, Nikazy J, Seebart KE, Schotz MC, (1991) Domain exchange: characterization of a chimeric lipase of hepatic lipase and lipoprotein lipase. Proc Natl Acad Sci U S A 88: 11290-11294.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 11290-11294
-
-
Wong, H.1
Davis, R.C.2
Nikazy, J.3
Seebart, K.E.4
Schotz, M.C.5
-
4
-
-
0032901331
-
A novel endothelial-derived lipase that modulates HDL metabolism
-
Jaye M, Lynch KJ, Krawiec J, Marchadier D, Maugeais C, et al. (1999) A novel endothelial-derived lipase that modulates HDL metabolism. Nat Genet 21: 424-428.
-
(1999)
Nat Genet
, vol.21
, pp. 424-428
-
-
Jaye, M.1
Lynch, K.J.2
Krawiec, J.3
Marchadier, D.4
Maugeais, C.5
-
5
-
-
0033553565
-
Cloning of a unique lipase from endothelial cells extends the lipase gene family
-
Hirata K, Dichek HL, Cioffi JA, Choi SY, Leeper NJ, et al. (1999) Cloning of a unique lipase from endothelial cells extends the lipase gene family. J Biol Chem 274: 14170-14175.
-
(1999)
J Biol Chem
, vol.274
, pp. 14170-14175
-
-
Hirata, K.1
Dichek, H.L.2
Cioffi, J.A.3
Choi, S.Y.4
Leeper, N.J.5
-
6
-
-
0035988350
-
Characterization of the lipolytic activity of endothelial lipase
-
McCoy MG, Sun GS, Marchadier D, Maugeais C, Glick JM, et al. (2002) Characterization of the lipolytic activity of endothelial lipase. J Lipid Res 43: 921-929.
-
(2002)
J Lipid Res
, vol.43
, pp. 921-929
-
-
McCoy, M.G.1
Sun, G.S.2
Marchadier, D.3
Maugeais, C.4
Glick, J.M.5
-
7
-
-
0028144804
-
Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins
-
Fan J, Wang J, Bensadoun A, Lauer SJ, Dang Q, et al. (1994) Overexpression of hepatic lipase in transgenic rabbits leads to a marked reduction of plasma high density lipoproteins and intermediate density lipoproteins. Proc Natl Acad Sci U S A 91: 8724-8728.
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 8724-8728
-
-
Fan, J.1
Wang, J.2
Bensadoun, A.3
Lauer, S.J.4
Dang, Q.5
-
8
-
-
20844457591
-
Macrophage-derived lipoprotein lipase increases aortic atherosclerosis in cholesterol-fed Tg rabbits
-
Ichikawa T, Liang J, Kitajima S, Koike T, Wang X, et al. (2005) Macrophage-derived lipoprotein lipase increases aortic atherosclerosis in cholesterol-fed Tg rabbits. Atherosclerosis 179: 87-95.
-
(2005)
Atherosclerosis
, vol.179
, pp. 87-95
-
-
Ichikawa, T.1
Liang, J.2
Kitajima, S.3
Koike, T.4
Wang, X.5
-
9
-
-
0041385950
-
Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice
-
Nong Z, Gonzalez-Navarro H, Amar M, Freeman L, Knapper C, et al. (2003) Hepatic lipase expression in macrophages contributes to atherosclerosis in apoE-deficient and LCAT-transgenic mice. J Clin Invest 112: 367-378.
-
(2003)
J Clin Invest
, vol.112
, pp. 367-378
-
-
Nong, Z.1
Gonzalez-Navarro, H.2
Amar, M.3
Freeman, L.4
Knapper, C.5
-
10
-
-
84859071500
-
Endothelial lipase mediates HDL levels in normal and hyperlipidemic rabbits
-
Zhang J, Yu Y, Nakamura K, Koike T, Waqar AB, et al. (2012) Endothelial lipase mediates HDL levels in normal and hyperlipidemic rabbits. J Atheroscler Thromb 19: 213-226.
-
(2012)
J Atheroscler Thromb
, vol.19
, pp. 213-226
-
-
Zhang, J.1
Yu, Y.2
Nakamura, K.3
Koike, T.4
Waqar, A.B.5
-
11
-
-
0036317550
-
The lipase gene family
-
Wong H, Schotz MC, (2002) The lipase gene family. J Lipid Res 43: 993-999.
-
(2002)
J Lipid Res
, vol.43
, pp. 993-999
-
-
Wong, H.1
Schotz, M.C.2
-
12
-
-
0027260912
-
The novel compound NO-1886 increases lipoprotein lipase activity with resulting elevation of high density lipoprotein cholesterol, and long-term administration inhibits atherogenesis in the coronary arteries of rats with experimental atherosclerosis
-
Tsutsumi K, Inoue Y, Shima A, Iwasaki K, Kawamura M, et al. (1993) The novel compound NO-1886 increases lipoprotein lipase activity with resulting elevation of high density lipoprotein cholesterol, and long-term administration inhibits atherogenesis in the coronary arteries of rats with experimental atherosclerosis. J Clin Invest 92: 411-417.
-
(1993)
J Clin Invest
, vol.92
, pp. 411-417
-
-
Tsutsumi, K.1
Inoue, Y.2
Shima, A.3
Iwasaki, K.4
Kawamura, M.5
-
13
-
-
0037314398
-
Endothelial lipase is a major determinant of HDL level
-
Ishida T, Choi S, Kundu RK, Hirata K, Rubin EM, et al. (2003) Endothelial lipase is a major determinant of HDL level. J Clin Invest 111: 347-355.
-
(2003)
J Clin Invest
, vol.111
, pp. 347-355
-
-
Ishida, T.1
Choi, S.2
Kundu, R.K.3
Hirata, K.4
Rubin, E.M.5
-
14
-
-
0032784276
-
Alpha/beta hydrolase fold enzymes: the family keeps growing
-
Nardini M, Dijkstra BW, (1999) Alpha/beta hydrolase fold enzymes: the family keeps growing. Curr Opin Struct Biol 9: 732-737.
-
(1999)
Curr Opin Struct Biol
, vol.9
, pp. 732-737
-
-
Nardini, M.1
Dijkstra, B.W.2
-
15
-
-
0023767035
-
The molecular evolution of genes and proteins: a tale of two serines
-
Brenner S, (1988) The molecular evolution of genes and proteins: a tale of two serines. Nature 334: 528-530.
-
(1988)
Nature
, vol.334
, pp. 528-530
-
-
Brenner, S.1
-
16
-
-
0026305078
-
Relationships among serine hydrolases: evidence for a common structural motif in triacylglyceride lipases and esterases
-
Derewenda ZS, Derewenda U, (1991) Relationships among serine hydrolases: evidence for a common structural motif in triacylglyceride lipases and esterases. Biochem Cell Biol 69: 842-851.
-
(1991)
Biochem Cell Biol
, vol.69
, pp. 842-851
-
-
Derewenda, Z.S.1
Derewenda, U.2
-
17
-
-
0038603851
-
Identification of a lipoprotein lipase cofactor-binding site by chemical cross-linking and transfer of apolipoprotein C-II-responsive lipolysis from lipoprotein lipase to hepatic lipase
-
McIlhargey TL, Yang Y, Wong H, Hill JS, (2003) Identification of a lipoprotein lipase cofactor-binding site by chemical cross-linking and transfer of apolipoprotein C-II-responsive lipolysis from lipoprotein lipase to hepatic lipase. J Biol Chem 278: 23027-23035.
-
(2003)
J Biol Chem
, vol.278
, pp. 23027-23035
-
-
McIlhargey, T.L.1
Yang, Y.2
Wong, H.3
Hill, J.S.4
-
18
-
-
0026675606
-
Human lipoprotein lipase. Analysis of the catalytic triad by site-directed mutagenesis of Ser-132, Asp-156, and His-241
-
Emmerich J, Beg OU, Peterson J, Previato L, Brunzell JD, et al. (1992) Human lipoprotein lipase. Analysis of the catalytic triad by site-directed mutagenesis of Ser-132, Asp-156, and His-241. J Biol Chem 267: 4161-4165.
-
(1992)
J Biol Chem
, vol.267
, pp. 4161-4165
-
-
Emmerich, J.1
Beg, O.U.2
Peterson, J.3
Previato, L.4
Brunzell, J.D.5
-
19
-
-
0025236967
-
Hepatic lipase: site-directed mutagenesis of a serine residue important for catalytic activity
-
Davis RC, Stahnke G, Wong H, Doolittle MH, Ameis D, et al. (1990) Hepatic lipase: site-directed mutagenesis of a serine residue important for catalytic activity. J Biol Chem 265: 6291-6295.
-
(1990)
J Biol Chem
, vol.265
, pp. 6291-6295
-
-
Davis, R.C.1
Stahnke, G.2
Wong, H.3
Doolittle, M.H.4
Ameis, D.5
-
20
-
-
0026802491
-
The catalytic site residues and interfacial binding of human pancreatic lipase
-
Lowe ME, (1992) The catalytic site residues and interfacial binding of human pancreatic lipase. J Biol Chem 267: 17069-17073.
-
(1992)
J Biol Chem
, vol.267
, pp. 17069-17073
-
-
Lowe, M.E.1
-
21
-
-
0028129833
-
Lipoprotein lipase. Molecular model based on the pancreatic lipase x-ray structure: consequences for heparin binding and catalysis
-
van Tilbeurgh H, Roussel A, Lalouel JM, Cambillau C, (1994) Lipoprotein lipase. Molecular model based on the pancreatic lipase x-ray structure: consequences for heparin binding and catalysis. J Biol Chem 269: 4626-4633.
-
(1994)
J Biol Chem
, vol.269
, pp. 4626-4633
-
-
van Tilbeurgh, H.1
Roussel, A.2
Lalouel, J.M.3
Cambillau, C.4
-
22
-
-
0026355156
-
Effects of gene mutations in lipoprotein and hepatic lipases as interpreted by a molecular model of the pancreatic triglyceride lipase
-
Derewenda ZS, Cambillau C, (1991) Effects of gene mutations in lipoprotein and hepatic lipases as interpreted by a molecular model of the pancreatic triglyceride lipase. J Biol Chem 266: 23112-23119.
-
(1991)
J Biol Chem
, vol.266
, pp. 23112-23119
-
-
Derewenda, Z.S.1
Cambillau, C.2
-
23
-
-
0033954256
-
The Protein Data Bank
-
Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, et al. (2000) The Protein Data Bank. Nucleic Acids Res 28: 235-242.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
Gilliland, G.4
Bhat, T.N.5
-
24
-
-
0027200087
-
Interfacial activation of the lipase-procolipase complex by mixed micelles revealed by X-ray crystallography
-
van Tilbeurgh H, Egloff MP, Martinez C, Rugani N, Verger R, et al. (1993) Interfacial activation of the lipase-procolipase complex by mixed micelles revealed by X-ray crystallography. Nature 362: 814-820.
-
(1993)
Nature
, vol.362
, pp. 814-820
-
-
van Tilbeurgh, H.1
Egloff, M.P.2
Martinez, C.3
Rugani, N.4
Verger, R.5
-
25
-
-
0000243829
-
PROCHECK: a program to check the stereochemical quality of protein structures
-
Laskowski RA, MacArthur MW, Moss DS, Thornton JM, (1993) PROCHECK: a program to check the stereochemical quality of protein structures. Journal of Applied Crystallography 26: 283-291.
-
(1993)
Journal of Applied Crystallography
, vol.26
, pp. 283-291
-
-
Laskowski, R.A.1
MacArthur, M.W.2
Moss, D.S.3
Thornton, J.M.4
-
26
-
-
27344454932
-
GROMACS: fast, flexible, and free
-
Van Der Spoel D, Lindahl E, Hess B, Groenhof G, Mark AE, et al. (2005) GROMACS: fast, flexible, and free. J Comput Chem 26: 1701-1718.
-
(2005)
J Comput Chem
, vol.26
, pp. 1701-1718
-
-
Van Der Spoel, D.1
Lindahl, E.2
Hess, B.3
Groenhof, G.4
Mark, A.E.5
-
29
-
-
0030211558
-
Conjugate gradient methods for power system dynamic simulation on parallel computers
-
Decker IC, Falcao DM, Kaszkurewicz E, (1996) Conjugate gradient methods for power system dynamic simulation on parallel computers. Power Systems, IEEE Transactions on 11: 1218-1227.
-
(1996)
Power Systems, IEEE Transactions on
, vol.11
, pp. 1218-1227
-
-
Decker, I.C.1
Falcao, D.M.2
Kaszkurewicz, E.3
-
30
-
-
33846823909
-
Particle mesh Ewald: An N-log(N) method for Ewald sums in large systems
-
Darden T, York D, Pedersen L, (1993) Particle mesh Ewald: An N-log(N) method for Ewald sums in large systems. The Journal of Chemical Physics 98: 10089-10092.
-
(1993)
The Journal of Chemical Physics
, vol.98
, pp. 10089-10092
-
-
Darden, T.1
York, D.2
Pedersen, L.3
-
31
-
-
0000388705
-
LINCS: A linear constraint solver for molecular simulations
-
Hess B, Bekker H, Berendsen HJC, Fraaije JGEM, (1997) LINCS: A linear constraint solver for molecular simulations. J Comput Chem 18: 1463-1472.
-
(1997)
J Comput Chem
, vol.18
, pp. 1463-1472
-
-
Hess, B.1
Bekker, H.2
Berendsen, H.J.C.3
Fraaije, J.G.E.M.4
-
32
-
-
84986440341
-
Settle: An analytical version of the SHAKE and RATTLE algorithm for rigid water models
-
Miyamoto S, Kollman PA, (1992) Settle: An analytical version of the SHAKE and RATTLE algorithm for rigid water models. J Comput Chem 13: 952-962.
-
(1992)
J Comput Chem
, vol.13
, pp. 952-962
-
-
Miyamoto, S.1
Kollman, P.A.2
-
33
-
-
84882631324
-
Binding Site Detection and Druggability Prediction of Protein Targets for Structure-Based Drug Design
-
In press
-
Yuan Y, Pei J, Lai L (2012) Binding Site Detection and Druggability Prediction of Protein Targets for Structure-Based Drug Design. Curr Pharm Des. In press.
-
(2012)
Curr Pharm Des
-
-
Yuan, Y.1
Pei, J.2
Lai, L.3
-
34
-
-
79960250991
-
LigBuilder 2: A Practical de Novo Drug Design Approach
-
In press
-
Yuan Y, Pei J, Lai L (2011) LigBuilder 2: A Practical de Novo Drug Design Approach. J Chem Inf Model. In press.
-
(2011)
J Chem Inf Model
-
-
Yuan, Y.1
Pei, J.2
Lai, L.3
-
35
-
-
76149120388
-
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
-
Trott O, Olson AJ, (2010) AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J Comput Chem 31: 455-461.
-
(2010)
J Comput Chem
, vol.31
, pp. 455-461
-
-
Trott, O.1
Olson, A.J.2
-
36
-
-
77957820654
-
Virtual screening for HIV protease inhibitors: a comparison of AutoDock 4 and Vina
-
Chang MW, Ayeni C, Breuer S, Torbett BE, (2010) Virtual screening for HIV protease inhibitors: a comparison of AutoDock 4 and Vina. PLoS One 5: e11955.
-
(2010)
PLoS One
, vol.5
-
-
Chang, M.W.1
Ayeni, C.2
Breuer, S.3
Torbett, B.E.4
-
37
-
-
61749093196
-
ChEMBL. An interview with John Overington, team leader, chemogenomics at the European Bioinformatics Institute Outstation of the European Molecular Biology Laboratory (EMBL-EBI). Interview by Wendy A. Warr
-
Overington J, (2009) ChEMBL. An interview with John Overington, team leader, chemogenomics at the European Bioinformatics Institute Outstation of the European Molecular Biology Laboratory (EMBL-EBI). Interview by Wendy A. Warr. J Comput Aided Mol Des 23: 195-198.
-
(2009)
J Comput Aided Mol Des
, vol.23
, pp. 195-198
-
-
Overington, J.1
-
38
-
-
0346962962
-
Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase
-
Ebdrup S, Sorensen LG, Olsen OH, Jacobsen P, (2004) Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase. J Med Chem 47: 400-410.
-
(2004)
J Med Chem
, vol.47
, pp. 400-410
-
-
Ebdrup, S.1
Sorensen, L.G.2
Olsen, O.H.3
Jacobsen, P.4
-
39
-
-
57749083133
-
Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors
-
Goodman KB, Bury MJ, Cheung M, Cichy-Knight MA, Dowdell SE, et al. (2009) Discovery of potent, selective sulfonylfuran urea endothelial lipase inhibitors. Bioorg Med Chem Lett 19: 27-30.
-
(2009)
Bioorg Med Chem Lett
, vol.19
, pp. 27-30
-
-
Goodman, K.B.1
Bury, M.J.2
Cheung, M.3
Cichy-Knight, M.A.4
Dowdell, S.E.5
-
40
-
-
84856230163
-
Design and synthesis of boronic acid inhibitors of endothelial lipase
-
O'Connell DP, LeBlanc DF, Cromley D, Billheimer J, Rader DJ, et al. (2012) Design and synthesis of boronic acid inhibitors of endothelial lipase. Bioorg Med Chem Lett 22: 1397-1401.
-
(2012)
Bioorg Med Chem Lett
, vol.22
, pp. 1397-1401
-
-
O'Connell, D.P.1
LeBlanc, D.F.2
Cromley, D.3
Billheimer, J.4
Rader, D.J.5
-
41
-
-
0030589190
-
A pancreatic lipase with a phospholipase A1 activity: crystal structure of a chimeric pancreatic lipase-related protein 2 from guinea pig
-
Withers-Martinez C, Carriere F, Verger R, Bourgeois D, Cambillau C, (1996) A pancreatic lipase with a phospholipase A1 activity: crystal structure of a chimeric pancreatic lipase-related protein 2 from guinea pig. Structure 4: 1363-1374.
-
(1996)
Structure
, vol.4
, pp. 1363-1374
-
-
Withers-Martinez, C.1
Carriere, F.2
Verger, R.3
Bourgeois, D.4
Cambillau, C.5
-
42
-
-
0029808302
-
Premature atherosclerosis in patients with familial chylomicronemia caused by mutations in the lipoprotein lipase gene
-
Benlian P, De Gennes JL, Foubert L, Zhang H, Gagne SE, et al. (1996) Premature atherosclerosis in patients with familial chylomicronemia caused by mutations in the lipoprotein lipase gene. N Engl J Med 335: 848-854.
-
(1996)
N Engl J Med
, vol.335
, pp. 848-854
-
-
Benlian, P.1
De Gennes, J.L.2
Foubert, L.3
Zhang, H.4
Gagne, S.E.5
-
43
-
-
0026337222
-
Catalytic triad residue mutation (Asp156--Gly) causing familial lipoprotein lipase deficiency. Co-inheritance with a nonsense mutation (Ser447--Ter) in a Turkish family
-
Faustinella F, Chang A, Van Biervliet JP, Rosseneu M, Vinaimont N, et al. (1991) Catalytic triad residue mutation (Asp156--Gly) causing familial lipoprotein lipase deficiency. Co-inheritance with a nonsense mutation (Ser447--Ter) in a Turkish family. J Biol Chem 266: 14418-14424.
-
(1991)
J Biol Chem
, vol.266
, pp. 14418-14424
-
-
Faustinella, F.1
Chang, A.2
Van Biervliet, J.P.3
Rosseneu, M.4
Vinaimont, N.5
-
44
-
-
0026046258
-
Amino acid substitution (Ile194--Thr) in exon 5 of the lipoprotein lipase gene causes lipoprotein lipase deficiency in three unrelated probands. Support for a multicentric origin
-
Henderson HE, Ma Y, Hassan MF, Monsalve MV, Marais AD, et al. (1991) Amino acid substitution (Ile194--Thr) in exon 5 of the lipoprotein lipase gene causes lipoprotein lipase deficiency in three unrelated probands. Support for a multicentric origin. J Clin Invest 87: 2005-2011.
-
(1991)
J Clin Invest
, vol.87
, pp. 2005-2011
-
-
Henderson, H.E.1
Ma, Y.2
Hassan, M.F.3
Monsalve, M.V.4
Marais, A.D.5
-
45
-
-
0026674914
-
A missense mutation Pro157 Arg in lipoprotein lipase (LPLNijmegen) resulting in loss of catalytic activity
-
Bruin T, Kastelein JJ, Van Diermen DE, Ma Y, Henderson HE, et al. (1992) A missense mutation Pro157 Arg in lipoprotein lipase (LPLNijmegen) resulting in loss of catalytic activity. Eur J Biochem 208: 267-272.
-
(1992)
Eur J Biochem
, vol.208
, pp. 267-272
-
-
Bruin, T.1
Kastelein, J.J.2
Van Diermen, D.E.3
Ma, Y.4
Henderson, H.E.5
-
46
-
-
0142105905
-
Characterization of a novel mutation causing hepatic lipase deficiency among French Canadians
-
Ruel IL, Couture P, Gagne C, Deshaies Y, Simard J, et al. (2003) Characterization of a novel mutation causing hepatic lipase deficiency among French Canadians. J Lipid Res 44: 1508-1514.
-
(2003)
J Lipid Res
, vol.44
, pp. 1508-1514
-
-
Ruel, I.L.1
Couture, P.2
Gagne, C.3
Deshaies, Y.4
Simard, J.5
-
47
-
-
0027162816
-
Hepatic lipase deficiency. Clinical, biochemical, and molecular genetic characteristics
-
Hegele RA, Little JA, Vezina C, Maguire GF, Tu L, et al. (1993) Hepatic lipase deficiency. Clinical, biochemical, and molecular genetic characteristics. Arterioscler Thromb 13: 720-728.
-
(1993)
Arterioscler Thromb
, vol.13
, pp. 720-728
-
-
Hegele, R.A.1
Little, J.A.2
Vezina, C.3
Maguire, G.F.4
Tu, L.5
-
48
-
-
80054911951
-
LigPlot+: multiple ligand-protein interaction diagrams for drug discovery
-
Laskowski RA, Swindells MB, (2011) LigPlot+: multiple ligand-protein interaction diagrams for drug discovery. J Chem Inf Model 51: 2778-2786.
-
(2011)
J Chem Inf Model
, vol.51
, pp. 2778-2786
-
-
Laskowski, R.A.1
Swindells, M.B.2
|