In Vivo Delivery of Adenoviral Vector Containing Interleukin-17 Receptor A Reduces Cardiac Remodeling and Improves Myocardial Function in Viral Myocarditis Leading to Dilated Cardiomyopathy

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Xie, Yuquan ^a,b   Li, Minghui ^a   Wang, Xinggang ^a   Zhang, Xian ^a   Peng, Tianqing ^c   Yang, Yingzhen ^a   Zou, Yunzeng ^a   Ge, Junbo ^a   Chen, Haozhu ^a   Chen, Ruizhen ^a  

^a FUDAN UNIVERSITY   (China)

^b XINHUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADAMTS1 PROTEIN; ADENOVIRUS VECTOR; COLLAGEN TYPE 1; COLLAGEN TYPE 3; GELATINASE A; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INTERLEUKIN 17; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CONGESTIVE CARDIOMYOPATHY; CYTOKINE PRODUCTION; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROBLAST; FLOW CYTOMETRY; HEART EJECTION FRACTION; HEART FUNCTION; HEART VENTRICLE REMODELING; IMMUNOFLUORESCENCE; IN VIVO STUDY; MALE; MORTALITY; MOUSE; NONHUMAN; RAT; TH17 CELL; TRANSTHORACIC ECHOCARDIOGRAPHY; VIRAL GENE DELIVERY SYSTEM; VIRUS MYOCARDITIS;

ADENOVIRIDAE; ANIMALS; CARDIOMYOPATHY, DILATED; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN; DOWN-REGULATION; GENETIC THERAPY; GENETIC VECTORS; INTERLEUKIN-17; INTERLEUKIN-6; MALE; MATRIX METALLOPROTEINASE 2; MICE; MICE, INBRED C57BL; MYOCARDITIS; MYOCARDIUM; MYOFIBROBLASTS; RATS; RATS, WISTAR; RECEPTORS, INTERLEUKIN-17; TH17 CELLS; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TUMOR NECROSIS FACTOR-ALPHA; VENTRICULAR REMODELING;

EID: 84882650816     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0072158     Document Type: Article

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