The E-domain region of mechano-growth factor inhibits cellular apoptosis and preserves cardiac function during myocardial infarction

Molecular and Cellular Biochemistry

Volumn 381, Issue 1-2, 2013, Pages 69-83

  Mavrommatis, Evangelos ^a   Shioura, Krystyna M ^a   Los, Tamara ^a   Goldspink, Paul H ^b  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Cardiac function; Cell death; E domain; IGF 1 isoforms; Myocardial infarction

Indexed keywords

CASPASE 3; GROWTH FACTOR; MECHANO GROWTH FACTOR; PEPTIDE E; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL STRESS; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; HEART FUNCTION; HEART INFARCTION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PROTEIN DOMAIN; PROTEIN FUNCTION; RAT;

ANIMALS; APOPTOSIS; CARDIOMEGALY; CELL LINE; GENE EXPRESSION REGULATION; HEART FUNCTION TESTS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCARDIUM; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; RATS; RECEPTOR, IGF TYPE 1; RNA, MESSENGER; STRESS, PHYSIOLOGICAL;

MUS;

EID: 84882569670     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-013-1689-4     Document Type: Article

References (45)

1. Cheng W, Kajstura J, Nitahara JA, Li B, Reiss K, Liu Y, Clark WA, Krajewski S, Reed JC, Olivetti G, Anversa P (1996) Programmed myocyte cell death affects the viable myocardium after infarction in rats. Exp Cell Res 226:316-327
2. Olivetti G, Melissari M, Balbi T, Quaini F, Cigola E, Sonnenblick EH, Anversa P (1994) Myocyte cellular hypertrophy is responsible for ventricular remodelling in the hypertrophied heart of middle aged individuals in the absence of cardiac failure. Car-diovasc Res 28:1199-1208
3. Muta K, Krantz SB (1993) Apoptosis of human erythroid colony-forming cellsisdecreased by stem cell factor and insulin-like growth factor I as well as erythropoietin. J Cell Physiol 156:264-271
4. Nagy N, Malik G, Fisher AB, Das DK (2006) Targeted disruption of peroxiredoxin 6 gene renders the heart vulnerable to ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol 291:H2636-H2640
5. Matthews KG, Devlin GP, Conaglen JV, Stuart SP, Mervyn Aitken W, Bass JJ (1999) Changes in IGFs in cardiac tissue following myocardial infarction. J Endocrinol 163:433-445
6. Reiss K, Kajstura J, Zhang X, Li P, Szoke E, Olivetti G, Anversa P (1994) Acute myocardial infarction leads to upregulation of the IGF-1 autocrine system, DNA replication, and nuclear mitotic division in the remaining viable cardiac myocytes. Exp Cell Res 213:463-472
7. Loennechen JP, Støylen A, Beisvag V, Wisloff U, Ellingsen O (2001) Regional expression of endothelin-1, ANP, IGF-1, and LV wall stress in the infarcted rat heart. Am J Physiol Heart Circ Physiol 280:H2902-H2910
8. Foyt HL, LeRoith D, Roberts CT (1991) Differential association of insulin-like growth factor I mRNA variants with polysomes in vivo. J Biol Chem 266:7300-7305
9. Shimatsu A, Rotwein P (1987) Mosaic evolution of the insulinlike growth factors. Organization, sequence, and expression of the rat insulin-like growth factor I gene. J Biol Chem 262: 7894-7900
10. Cheema U, Yang SY, Mudera V, Goldspink G, Brown RA (2003) 3-D in vitro model of early skeletal muscle development. Cell Motil Cytoskeleton 54:226-236
11. Goldspink G, Yang SY (2004) The splicing of the IGF-I gene to yield different muscle growth factors. Adv Genet 52:23-49
12. Hill MA, Goldspink G (2003) Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite (stem) cell activation following local tissue damage. J Physiol 549:409-418
13. McKoy G, Ashley W, Mander J, Yang SY, Williams N, Russell B, Goldspink G (1999) Expression of insulin growth factor-1 splice variants and structural genes in rabbit skeletal muscle induced by stretch and stimulation. J Physiol 516:583-592
14. Yang S Alnaqeeb M, Simpson H, Goldspink G (1996) Cloning and characterization of an IGF-1 isoform expressed in skeletal muscle subjected to stretch. J Muscle Res Cell Motil 17:487-495
15. Barton ER, DeMeo J, Lei H (2010) The insulin-like growth factor (IGF)-I E-peptides are required for isoform-specific gene expression and muscle hypertrophy after local IGF-I production. J Appl Physiol 108:1069-1076
16. Morales MP, Gálvez A, José Miguel Eltit JM, Ocaranza P, Díaz-Araya G, Lavandero S (2000) IGF-1 regulates apoptosis of cardiac myocyte induced by osmotic-stress. Biochem Biophys Res Commun 270:1029-1035
17. Yang SY, Goldspink G (2002) Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation. FEBS Lett 522:156-160
18. Stavropoulou A, Halapas A, Sourla A, Philippou A, Papageorgiou E, Papalois A, Koutsilieris M (2009) IGF-1 expression in infarcted myocardium and MGF E peptide actions on rat cardiomyocytes in vitro. Mol Med 15:127-135
19. Carpenter VC, Matthews KG, Devlin GP, Stuart SP, Jensen JA, Conaglen JV, Jeanplong F, Goldspink PH, Yang SY, Goldspink G, Bass JJ, McMahon CD (2008) Mechano-growth factor ameliorates loss of cardiac function in acute myocardial infarction. Heart Lung Circ 17:33-39
20. Dluzniewska J, Sarnowska A, Beresewicz M, Johnsomn I, Srai SK, Ramesh B, Goldspink G, Gorecki DC, Zablocka B (2005) A strong neuroprotective effect of the autonomous C-terminal peptide of IGF-1 Ec (MGF) in brain ischemia. FASEB J 19: 1896-1898
21. Shioura KM, Geenen DL, Goldspink PH (2007) Assessment of cardiac function with the pressure-volume conductance system following myocardial infarction in mice. Am J Physiol Heart Circ Physiol 293:H2870-H2877
22. Goldspink PH, Montgomery DE, Walker LA, Urboniene D, McKinney RD, Geenen DL, Solaro RJ, Buttrick PM (2004) Protein kinase Ce over-expression alters myofilament properties and composition during the progression of heart failure. Circ Res 95:424-432
23. Galvez A, Morales MP, Eltit JM, Ocaranza P, Carrasco L, Campos X, Sapag-Hagar M, Diaz-Araya G, Lavandero S (2001) A rapid and strong apoptotic process is triggered by hyperosmotic stress in cultured rat cardiac myocytes. Cell Tissue Res 304: 279-285
24. Sánchez-Más J, Turpín MC, Lax A, Ruipérez JA, Valdés Cháv-arri M, Pascual-Figal DA (2010) Differential actions of eplere-none and spironolactone on the protective effect of testosterone against cardiomyocyte apoptosis in vitro. Rev Esp Cardiol 63: 779-787
25. Mao YW, Liu JP, Xiang H, Li DW (2004) Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis. Cell Death Differ 11:512-526
26. Galvez AS, Ulloa JA, Chiong M, Criollo A, Eisner V, Barros LF, Lavandero S (2003) Aldose reductase induced by hyperosmotic stress mediates cardiomyocyte apoptosis: differential effects of sorbitol and mannitol. J Biol Chem 278:38484-38494
27. Morrison LE, Hoover HE, Thuerauf DJ, Glembotski CC (2003) Mimicking phosphorylation of alphaB-crystallin on serine-59 is necessary and sufficient to provide maximal protection of cardiac myocytes from apoptosis. Circ Res 92:203-211
28. + exchanger in neonatal ventricular myocytes. J Mol Cell Cardiol 32:925-936
29. Chiong M, Parra V, Eisner V, Ibarra C, Maldonado C, Criollo A, Bravo R, Quiroga C, Contreras A, Vicencio JM, Cea P, Bucarey JL, Molgó J, Jaimovich E, Hidalgo C, Kroemer G, Lavandero S (2010) Parallel activation of Ca(2+)-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress. Apoptosis 15:887-903
30. Kajstura J, Cheng W, Reiss K, Clark WA, Sonnenblick EH, Krajewski S, Reed JC, Olivetti G, Anversa P (1996) Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats. Lab Invest 74:86-107
31. Donath MY, Zierhut W, Gosteli-Peter MA, Hauri C, Froesch ER, Zapf J (1998) Effects of IGF-I on cardiac growth and expression of mRNAs coding for cardiac proteins after induction of heart hypertrophy in the rat. Eur J Endocrinol 139:109-117
32. Napier JR, Thomas MF, Sharma M, Hodgkinson SC, Bass JJ (1999) Insulin-like growth factor-I protects myoblasts from apoptosis but requires other factors to stimulate proliferation. J Endocrinol 163:63-68
33. Duerr RL, Huang S, Miraliakbar HR, Clark R, Chien KR, Ross J Jr (1996) Insulin-like growth factor-1 enhances ventricular hypertrophy and function during the onset of experimental cardiac failure. J Clin Invest 95:619-627
34. Duerr RL, McKirnan MD, Gim RD, Clark RG, Chien KR, Ross J Jr (1996) Cardiovascular effects of insulin-like growth factor-1 and growth hormone in chronic left ventricular failure in the rat. Circulation 93:2188-2196
35. Osterziel JK, Strohm O, Schuler J, Friedrich M, Hänlein D, Willenbrock R, Anker SD, Poole-Wilson PA, Ranke MB, Dietz R (1998) Randomized, double-blind, placebo-controlled trial of human recombinant growth hormone in patients with chronic heart failure due to dilated cardiomyopathy. Lancet 351:1233-1237
36. Colao A (2004) Cardiovascular effects of growth hormone treatment: potential risks and benefits. Horm Res 62:42-50
37. Conti E, Andreotti F, Sciahbasi A, Riccardi P, Marra G, Menini E, Ghirlanda G, Maseri A (2001) Markedly reduced insulin-like growth factor-1 in the acute phase of myocardial infarction. J Am Coll Cardiol 38:26-32
38. Li Q, Li B, Wang X, Leri A, Jana KP, Liu Y, Kajstura J, Baserga R, Anversa P (1997) Overexpression of insulin-like growth fac-tor-1 in mice protects from myocyte death after infarction, attenuating ventricular dilation, wall stress, and cardiac hypertrophy. J Clin Invest 100:1991-1999
39. Santini MP, Tsao L, Monassier L, Theodoropoulos C, Carter J, Lara-Pezzi E, Slonimsky E, Salimova E, Delafontaine P, Song SY, Bergmann M, Freund C, Suzuki K, Rosenthal N (2007) Enhancing repair of the mammalian heart. Circ Res 100:1732-1740
40. Quesada A, Micevych P, Handforth A (2009) C-terminal mec-hano-growth factor protects dopamine neurons: a novel peptide that induces heme oxygenase-1. Exp Neurol 220:255-266
41. Quesada A, Ogi J, Schultz J, Handforth A (2001) C-terminal mechano-growth factor induces heme oxygenase-1-mediated neuroprotection of SH-SY5Y cells via the protein kinase Ce/Nrf2 pathway. J Neurosci Res 89:394-405
42. TanakaN, RyokeT, HongoM, MaoL, RockmanHA, ClarkRG, Ross J Jr (1998) Effects of growth hormone and IGF-I on cardiac hypertrophy and gene expression in mice. Am J Physiol 275:H393-H399
43. Welch S, Plank D, Witt S, Glascock B, Schaefer E, Chimenti S, AndreoliAM, LimanaF, LeriA, KajsturaJ, AnversaP, Sussman MA (2002) Cardiac-specific IGF-1 expression attenuates dilated car-diomyopathy in tropomodulin-overexpressing transgenic mice. Circ Res 90:641-648
44. Duguay SJ, Lai-Zhang J, Steiner DF (1995) Mutational analysis of the insulin-like growth factor I prohormone processing site. J Biol Chem 270:17566-17574
45. Siegfried JJM, Kasprzyk PG, Treston AM, Mulshine JL, Quinn KA, Cuttitta F (1992) A mitogenic peptide amide encoded within the E peptide domain of the insulin-like growth factor IB prohormone. Proc Natl Acad Sci USA 89:8107-8111