Architecture of the Olfactory Bulb

The Senses: A Comprehensive Reference

Volumn 4, Issue , 2008, Pages 623-640

  Greer, C A ^a   Whitman, M C ^a   Rela, L ^a   Imamura, F ^a   Rodriguez Gil, D ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Granule cells; Mitral cells; Olfactory bulb; Olfactory circuitry; Olfactory sensory neuron; Periglomerular cells; Synaptic organization; Tufted cells

Indexed keywords

EID: 84882538753     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012370880-9.00117-1     Document Type: Chapter

References (113)

1. Altman J. Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulb. J. Comp. Neurol. 1969, 137:433-457.
2. Alvarez-Buylla A., Garcia-Verdugo J.M. Neurogenesis in adult subventricular zone. J. Neurosci. 2002, 22:629-634.
3. Andres K.H. The fine structure of the olfactory bulb in rats with special reference to the synaptic connections. Z. Zellforsch. Mikrosk. Anat. 1965, 65:530-561.
4. Au W.W., Treloar H.B., Greer C.A. Sublaminar organization of the mouse olfactory bulb nerve layer. J. Comp. Neurol. 2002, 446:68-80.
5. Aungst J.L., Heyward P.M., Puche A.C., Karnup S.V., Hayar A., Szabo G., Shipley M.T. Centre-surround inhibition among olfactory bulb glomeruli. Nature 2003, 426:623-629.
6. Bailey M.S., Shipley M.T. Astrocyte subtypes in the rat olfactory bulb: morphological heterogeneity and differential laminar distribution. J. Comp. Neurol. 1993, 328:501-526.
7. Bartolomei J.C., Greer C.A. Olfactory ensheathing cells: bridging the gap in spinal cord injury. Neurosurgery 2000, 47:1057-1069.
8. Belluscio L., Lodovichi C., Feinstein P., Mombaerts P., Katz L.C. Odorant receptors instruct functional circuitry in the mouse olfactory bulb. Nature 2002, 419:296-300.
9. Blanes T. Sobre algunos puntos dudoses de la estructuradel bulbo olfatorio. Revta Trimest. Microgr. 1898, 3:99-127.
10. Buck L., Axel R. A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell 1991, 65:175-187.
11. Cameron H.A., Kaliszewski C.K., Greer C.A. Organization of mitochondria in olfactory bulb granule cell dendritic spines. Synapse 1991, 8:107-118.
12. Carson K.A. Quantitative localization of neurons projecting to the mouse main olfactory bulb. Brain Res. Bull. 1984, 12:629-634.
13. Chang C.Y., Chien H.F., Jiangshieh Y.F., Wu C.H. Microglia in the olfactory bulb of rats during postnatal development and olfactory nerve injury with zinc sulfate: a lectin labeling and ultrastrucutural study. Neurosci. Res. 2003, 45:325-333.
14. Chao T.I., Kasa P., Wolff J.R. Distribution of astroglia in glomeruli of the rat main olfactory bulb: exclusion from the sensory subcompartment of neuropil. J. Comp. Neurol. 1997, 388:191-210.
15. Chen W.R., Shepherd G.M. The olfactory glomerulus: a cortical module with specific functions. J. Neurocytol. 2006, 34:353-360.
16. Chess A., Simon I., Cedar H., Axel R. Allelic inactivation regulates olfactory receptor gene expression. Cell 1994, 78:823-834.
17. Christie J.M., Bark C., Hormuzdi S.G., Helbig I., Monyer H., Westbrook G.L. Connexin36 mediates spike synchrony in olfactory bulb glomeruli. Neuron 2005, 46:761-772.
18. Cuschieri A., Bannister L.H. The development of the olfactory mucosa in the mouse: electron microscopy. J. Anat. 1975, 119:471-498.
19. de Olmos J., Hardy H., Heimer L. The afferent connections of the main and the accessory olfactory bulb formations in the rat: an experimental HRP-study. J. Comp. Neurol. 1978, 181:213-244.
20. Doetsch F., Hen R. Young and excitable: the function of new neurons in the adult mammalian brain. Curr. Opin. Neurobiol. 2005, 15:121-128.
21. Doucette J.R. The glial cells in the nerve fiber layer of the rat olfactory bulb. Anat. Rec. 1984, 210:385-391.
22. Doucette R. Glial influences on axonal growth in the primary olfactory system. Glia 1990, 3:433-449.
23. Doucette R. PNS-CNS transitional zone of the first cranial nerve. J. Comp. Neurol. 1991, 312:451-466.
24. Doucette R. Glial cells in the nerve fiber layer of the main olfactory bulb of embryonic and adult mammals. Microsc. Res. Tech. 1993, 24:113-130.
25. Feinstein P., Mombaerts P. A contextual model for axonal sorting into glomeruli in the mouse olfactory system. Cell 2004, 117:817-831.
26. Frazier L.L., Brunjes P.C. Unilateral odor deprivation: early postnatal changes in olfactory bulb cell density and number. J. Comp. Neurol. 1988, 269:355-370.
27. Fukushima N., Oikawa S., Yokouchi K., Kawagishi K., Moriizumi T. The minimum number of neurons in the central olfactory pathway in relation to its function: a retrograde fiber tracing study. Chem. Senses 2002, 27:1-6.
28. Galarreta M., Hestrin S. Electrical synapses between GABA-releasing interneurons. Nat. Rev. Neurosci. 2001, 2:425-433.
29. Gibson J.R., Beierlein M., Connors B.W. Two networks of electrically coupled inhibitory neurons in neocortex. Nature 1999, 402:75-79.
30. Graziadei P.P.C., Monti-Graziadei G.A. Continuous Nerve Cell Renewal in the Olfactory System. Development of Sensory Systems 1978, Vol. IX:55-83. Springer. M. Jacobson (Ed.).
31. Greer C.A. Golgi analyses of dendritic organization among denervated olfactory bulb granule cells. J. Comp. Neurol. 1987, 257:442-452.
32. Haberly L.B., Price J.L. The axonal projection patterns of the mitral and tufted cells of the olfactory bulb in the rat. Brain Res. 1977, 129:152-157.
33. Haberly L.B., Price J.L. Association and commissural fiber systems of the olfactory cortex of the rat. II. Systems originating in the olfactory peduncle. J. Comp. Neurol. 1978, 181:781-807.
34. Haberly L.B., Price J.L. Association and commissural fiber systems of the olfactory cortex of the rat. J. Comp. Neurol. 1978, 178:711-740.
35. Hirata Y. Some observations on the fine structure of the synapses in the olfactory bulb of the mouse, with particular reference to the atypical synaptic configurations. Arch. Histol. Jpn. 1964, 24:293-302.
36. Hisaoka T., Morikawa Y., Kitamura T., Senba E. Expression of a member of tumor necrosis factor receptor superfamily, TROY, in the developing olfactory system. Glia 2004, 45:313-324.
37. Imai T., Suzuki M., Sakano H. Odorant receptor-derived cAMP signals direct axonal targeting. Science 2006, 314:657-661.
38. Imamura F., Nagao H., Naritsuka H., Murata Y., Taniguchi H., Mori K. A leucine-rich repeat membrane protein, 5T4, is expressed by a subtype of granule cells with dendritic arbors in specific strata of the mouse olfactory bulb. J. Comp. Neurol. 2006, 495:754-768.
39. Iwema C.L., Fang H., Kurtz D.B., Youngentob S.L., Schwob J.E. Odorant receptor expression patterns are restored in lesion-recovered rat olfactory epithelium. J. Neurosci. 2004, 24:356-369.
40. Jackowski A., Parnavelas J.G., Lieberman A.R. The reciprocal synapse in the external plexiform layer of the mammalian olfactory bulb. Brain Res. 1978, 159:17-28.
41. Kafitz K.W., Greer C.A. Olfactory ensheathing cells promote neurite extension from embryonic olfactory receptor cells in vitro. Glia 1999, 25:99-110.
42. Kaplan M.S., Hinds J.W. Neurogenesis in the adult rat: electron microscopic analysis of light radioautographs. Science 1977, 197:1092-1094.
43. Kasowski H.J., Kim H., Greer C.A. Compartmental organization of the olfactory bulb glomerulus. J. Comp. Neurol. 1999, 407:261-274.
44. Kishi K., Mori K., Ojima H. Distribution of local axon collaterals of mitral, displaced mitral, and tufted cells in the rabbit olfactory bulb. J. Comp. Neurol. 1984, 225:511-526.
45. Klenoff J.R., Greer C.A. Postnatal development of olfactory receptor cell axonal arbors. J. Comp. Neurol. 1998, 390:256-267.
46. Kosaka K., Kosaka T. Synaptic organization of the glomerulus in the main olfactory bulb: compartments of the glomerulus and heterogeneity of the periglomerular cells. Anat. Sci. Int. 2005, 80:80-90.
47. Kosaka T., Kosaka K. Intraglomerular dendritic link connected by gap junctions and chemical synapses in the mouse main olfactory bulb: electron microscopic serial section analyses. Neuroscience 2005, 131:611-625.
48. Landis D.M., Reese T.S., Raviola E. Differences in membrane structure between excitatory and inhibitory components of the reciprocal synapse in the olfactory bulb. J. Comp. Neurol. 1974, 155:67-91.
49. Lennington J.B., Yang Z., Conover J.C. Neural stem cells and the regulation of adult neurogenesis. Reprod. Biol. Endocrinol. 2003, 1:99.
50. Liu W.L., Shipley M.T. Intrabulbar associational system in the rat olfactory bulb comprises cholecystokinin-containing tufted cells that synapse onto the dendrites of GABAergic granule cells. J. Comp. Neurol. 1994, 346:541-558.
51. Lledo P.M., Saghatelyan A. Integrating new neurons into the adult olfactory bulb: joining the network, life-death decisions, and the effects of sensory experience. Trends Neurosci. 2005, 28:248-254.
52. Lledo P.M., Alonso M., Grubb M.S. Adult neurogenesis and functional plasticity in neuronal circuits. Nat. Rev. Neurosci. 2006, 7:179-193.
53. Lodovichi C., Belluscio L., Katz L.C. Functional topography of connections linking mirror-symmetric maps in the mouse olfactory bulb. Neuron 2003, 38:265-276.
54. Lois C., Alvarez-Buylla A. Long-distance neuronal migration in the adult mammalian brain. Science 1994, 264:1145-1148.
55. Lois C., Garcia-Verdugo J.M., Alvarez-Buylla A. Chain migration of neuronal precursors. Science 1996, 271:978-981.
56. Luskin M.B., Price J.L. The distribution of axon collaterals from the olfactory bulb and the nucleus of the horizontal limb of the diagonal band to the olfactory cortex, demonstrated by double retrograde labeling techniques. J. Comp. Neurol. 1982, 209:249-263.
57. Luskin M.B., Price J.L. The topographic organization of associational fibers of the olfactory system in the rat, including centrifugal fibers to the olfactory bulb. J. Comp. Neurol. 1983, 216:264-291.
58. Luskin M.B., Price J.L. The laminar distribution of intracortical fibers originating in the olfactory cortex of the rat. J. Comp. Neurol. 1983, 216:292-302.
59. Macrides F., Schneider S.P. Laminar organization of mitral and tufted cells in the main olfactory bulb of the adult hamster. J. Comp. Neurol. 1982, 208:419-430.
60. Marks C.A., Cheng K., Cummings D.M., Belluscio L. Activity-dependent plasticity in the olfactory intrabulbar map. J. Neurosci. 2006, 26:11257-11266.
61. McLean J.H., Shipley M.T. Serotonergic afferents to the rat olfactory bulb. I. Origins and laminar specificity of serotonergic inputs in the adult rat. J. Neurosci. 1987, 7:3016-3028.
62. McLean J.H., Shipley M.T. Postnatal development of the noradrenergic projection from locus coeruleus to the olfactory bulb in the rat. J. Comp. Neurol. 1991, 304:467-477.
63. McLean J.H., Shipley M.T., Nickell W.T., Aston-Jones G., Reyher C.K. Chemoanatomical organization of the noradrenergic input from locus coeruleus to the olfactory bulb of the adult rat. J. Comp. Neurol. 1989, 285:339-349.
64. Miragall F., Simburger E., Dermietzel R. Mitral and tufted cells of the mouse olfactory bulb possess gap junctions and express connexin43 mRNA. Neurosci. Lett. 1996, 216:199-202.
65. Miyamichi K., Serizawa S., Kimura H.M., Sakano H. Continuous and overlapping expression domains of odorant receptor genes in the olfactory epithelium determine the dorsal/ventral positioning of glomeruli in the olfactory bulb. J. Neurosci. 2005, 25:3586-3592.
66. Mombaerts P., Wang F., Dulac C., Chao S.K., Nemes A., Mendelsohn M., Edmondson J., Axel R. Visualizing an olfactory sensory map. Cell 1996, 87:675-686.
67. Mori K., Kishi K., Ojima H. Distribution of dendrites of mitral, displaced mitral, tufted, and granule cells in the rabbit olfactory bulb. J. Comp. Neurol. 1983, 219:339-355.
68. Mori K., Nowycky M.C., Shepherd G.M. Electrophysiological analysis of mitral cells in the isolated turtle olfactory bulb. J. Physiol. 1981, 314:281-294.
69. Newman M.P., Feron F., Mackay-Sim A. Growth factor regulation of neurogenesis in adult olfactory epithelium. Neuroscience 2000, 99:343-350.
70. Orona E., Rainer E.C., Scott J.W. Dendritic and axonal organization of mitral and tufted cells in the rat olfactory bulb. J. Comp. Neurol. 1984, 226:346-356.
71. Orona E., Scott J.W., Rainer E.C. Different granule cell populations innervate superficial and deep regions of the external plexiform layer in rat olfactory bulb. J. Comp. Neurol. 1983, 217:227-237.
72. Pinching A.J., Powell T.P. The neuropil of the glomeruli of the olfactory bulb. J. Cell. Sci. 1971, 9:347-377.
73. Pinching A.J., Powell T.P. The neuropil of the periglomerular region of the olfactory bulb. J. Cell. Sci. 1971, 9:379-409.
74. Pinching A.J., Powell T.P. The neuron types of the glomerular layer of the olfactory bulb. J. Cell. Sci. 1971, 9:305-345.
75. Pinching A.J., Powell T.P. Experimental studies on the axons intrinsic to the glomerular layer of the olfactory bulb. J. Cell. Sci. 1972, 10:637-655.
76. Pressler R.T., Strowbridge B.W. Blanes cells mediate persistent feedforward inhibition onto granule cells in the olfactory bulb. Neuron 2006, 49:889-904.
77. Price J.L., Powell T.P. The morphology of the granule cells of the olfactory bulb. J. Cell Sci. 1970, 7:91-123.
78. Price J.L., Powell T.P. The synaptology of the granule cells of the olfactory bulb. J. Cell Sci. 1970, 7:125-155.
79. Price J.L., Powell T.P. The mitral and short axon cells of the olfactory bulb. J. Cell Sci. 1970, 7:631-651.
80. Price J.L., Sprich W.W. Observations on the lateral olfactory tract of the rat. J. Comp. Neurol. 1975, 162:321-336.
81. Rall W., Shepherd G.M., Reese T.S., Brightman M.W. Dendrodendritic synaptic pathway for inhibition in the olfactory bulb. Exp. Neurol. 1966, 14:44-56.
82. Ramon-Cueto A., Plant G.W., Avila J., Bunge M.B. Long-distance axonal regeneration in the transected adult rat spinal cord is promoted by olfactory ensheathing glia transplants. J. Neurosci. 1998, 18:3803-3815.
83. Ramón y Cajal S. Histologie du Système Nerveux de l'Homme et des Vertébrés 1911, Maloine, Paris.
84. Rash J.E., Davidson K.G., Kamasawa N., Yasumura T., Kamasawa M., Zhang C., Michaels R., Restrepo D., Ottersen O.P., Olson C.O., Nagy J.I. Ultrastructural localization of connexins (Cx36, Cx43, Cx45), glutamate receptors and aquaporin-4 in rodent olfactory mucosa, olfactory nerve and olfactory bulb. J. Neurocytol. 2005, 34:307-341.
85. Rash J.E., Yasumura T., Dudek F.E. Ultrastructure, histological distribution, and freeze-fracture immunocytochemistry of gap junctions in rat brain and spinal cord. Cell Biol. Int. 1998, 22:731-749.
86. Reyher C.K., Lubke J., Larsen W.J., Hendrix G.M., Shipley M.T., Baumgarten H.G. Olfactory bulb granule cell aggregates: morphological evidence for interperikaryal electrotonic coupling via gap junctions. J. Neurosci. 1991, 11:1485-1495.
87. Rela L., Szczupak L. Gap junctions: their importance for the dynamics of neural circuits. Mol. Neurobiol. 2004, 30:341-357.
88. Ressler K.J., Sullivan S.L., Buck L.B. A zonal organization of odorant receptor gene expression in the olfactory epithelium. Cell 1993, 73:597-609.
89. Royet J.P., Distel H., Hudson R., Gervais R. A re-estimation of the number of glomeruli and mitral cells in the olfactory bulb of rabbit. Brain Res. 1998, 788:35-42.
90. Schild D., Riedel H. Significance of glomerular compartmentalization for olfactory coding. Biophys. J. 1992, 61:704-715.
91. Schneider S.P., Macrides F. Laminar distributions of internuerons in the main olfactory bulb of the adult hamster. Brain Res. Bull. 1978, 3:73-82.
92. Schoppa N.E., Westbrook G.L. Glomerulus-specific synchronization of mitral cells in the olfactory bulb. Neuron 2001, 31:639-651.
93. Schwob J.E., Price J.L. The development of lamination of afferent fibers to the olfactory cortex in rats, with additional observations in the adult. J. Comp. Neurol. 1984, 223:203-222.
94. Scott J.W., McBride R.L., Schneider S.P. The organization of projections from the olfactory bulb to the piriform cortex and olfactory tubercle in the rat. J. Comp. Neurol. 1980, 194:519-534.
95. Serizawa S., Miyamichi K., Nakatani H., Suzuki M., Saito M., Yoshihara Y., Sakano H. Negative feedback regulation ensures the one receptor-one olfactory neuron rule in mouse. Science 2003, 302:2088-2094.
96. Serizawa S., Miyamichi K., Takeuchi H., Yamagishi Y., Suzuki M., Sakano H. A neuronal identity code for the odorant receptor-specific and activity-dependent axon sorting. Cell 2006, 127:1057-1069.
97. Shepherd G.M. Synaptic organization of the mammalian olfactory bulb. Physiol. Rev. 1972, 52:864-917.
98. Shepherd G.M., Chen W., Greer C.A. Olfactory Bulb. Synaptic Organization of the Brain 2004, 165-216. Oxford University Press. G.M. Sherpherd (Ed.).
99. Shipley M.T., Adamek G.D. The connections of the mouse olfactory bulb: a study using orthograde and retrograde transport of wheat germ agglutinin conjugated to horseradish peroxidase. Brain Res. Bull. 1984, 12:669-688.
100. Shipley M.T., Ennis M. Functional organization of olfactory system. J. Neurobiol. 1996, 30:123-176.
101. Treloar H.B., Feinstein P., Mombaerts P., Greer C.A. Specificity of glomerular targeting by olfactory sensory axons. J. Neurosci. 2002, 22:2469-2477.
102. Vassar R., Ngai J., Axel R. Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium. Cell 1993, 74:309-318.
103. Wachowiak M., Shipley M.T. Coding and synaptic processing of sensory information in the glomerular layer of the olfactory bulb. Semin. Cell Dev. Biol. 2006, 17:411-423.
104. Westrum L.E. Electron microscopy of synaptic structures in olfactory cortex of early postnatal rats. J. Neurocytol. 1975, 4:713-732.
105. Whitman M.C., Greer C.A. Adult-generated neurons exhibit diverse developmental fates. Dev. Neurobiol. 2007, 67:1079-1093.
106. Willhite D.C., Nguyen K.T., Masurkar A.V., Greer C.A., Shepherd G.M., Chen W.R. Viral tracing identifies distributed columnar organization in the olfactory bulb. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:12592-12597.
107. Wilson D.A., Kadohisa M., Fletcher M.L. Cortical contributions to olfaction: plasticity and perception. Semin. Cell Dev. Biol. 2006, 17:462-470.
108. Woolf T.B., Shepherd G.M., Greer C.A. Serial reconstructions of granule cell spines in the mammalian olfactory bulb. Synapse 1991, 7:181-192.
109. Woolf T.B., Shepherd G.M., Greer C.A. Local information processing in dendritic trees: subsets of spines in granule cells of the mammalian olfactory bulb. J. Neurosci. 1991, 11:1837-1854.
110. Wouterlood F.G., Nederlof J. Terminations of olfactory afferents on layer II and III neurons in the entorhinal area: degeneration-Golgi-electron microscopic study in the rat. Neurosci. Lett. 1983, 36:105-110.
111. Zou D.J., Feinstein P., Rivers A.L., Mathews G.A., Kim A., Greer C.A., Mombaerts P., Firestein S. Postnatal refinement of peripheral olfactory projections. Science 2004, 304:1976-1979.
112. Zou Z., Li F., Buck L.B. Odor maps in the olfactory cortex. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:7724-7729.
113. Zou Z., Horowitz L.F., Montmayeur J.P., Snapper S., Buck L.B. Genetic tracing reveals a stereotyped sensory map in the olfactory cortex. Nature 2001, 414:173-179.