-
1
-
-
0024292722
-
Most human carcinomas of the endocrine pancreas contain mutant c-K- ras genes
-
Almoguerra C., Shibata D., Forrester K., Martin J., Arnheim M., Perucho M. Most human carcinomas of the endocrine pancreas contain mutant c-K- ras genes. Cell 1988, 53:813-815.
-
(1988)
Cell
, vol.53
, pp. 813-815
-
-
Almoguerra, C.1
Shibata, D.2
Forrester, K.3
Martin, J.4
Arnheim, M.5
Perucho, M.6
-
2
-
-
67349189383
-
The kinetics of formation of native ribonuclease during oxidation of the reduced polypeptide chain
-
Anfinsen C.B., Haber E., Sela M., White F.H. The kinetics of formation of native ribonuclease during oxidation of the reduced polypeptide chain. Proc Natl Acad Sci USA 1961, 47:1309-1314.
-
(1961)
Proc Natl Acad Sci USA
, vol.47
, pp. 1309-1314
-
-
Anfinsen, C.B.1
Haber, E.2
Sela, M.3
White, F.H.4
-
4
-
-
0024042025
-
Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion
-
Bargmann C.I., Weinberg R.A. Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion. EMBO J 1988, 7:2043-2052.
-
(1988)
EMBO J
, vol.7
, pp. 2043-2052
-
-
Bargmann, C.I.1
Weinberg, R.A.2
-
5
-
-
0026800884
-
An oncogenic point mutation confers high affinity ligand binding to the neu receptor
-
Ben-Levy R., Peles E., Goldman-Michael R., Yarden Y. An oncogenic point mutation confers high affinity ligand binding to the neu receptor. J Biol Chem 1992, 267:17304-17313.
-
(1992)
J Biol Chem
, vol.267
, pp. 17304-17313
-
-
Ben-levy, R.1
Peles, E.2
Goldman-michael, R.3
Yarden, Y.4
-
6
-
-
0018587968
-
Translocation of proteins across membranes: the signal hypothesis and beyond
-
Blobel G., Walter P., Chang C.N., Goldman B.M., Erickson A.H., Lingappa R. Translocation of proteins across membranes: the signal hypothesis and beyond. Symp Soc Exp Biol 1979, 33:9-37.
-
(1979)
Symp Soc Exp Biol
, vol.33
, pp. 9-37
-
-
Blobel, G.1
Walter, P.2
Chang, C.N.3
Goldman, B.M.4
Erickson, A.H.5
Lingappa, R.6
-
7
-
-
57749116040
-
On the mechanism of pore formation by melittin
-
Bogaart G.V.D., Guzman J.V., Mica J.T., Poolman B. On the mechanism of pore formation by melittin. J Biol Chem 2008, 283:33854-33857.
-
(2008)
J Biol Chem
, vol.283
, pp. 33854-33857
-
-
Bogaart, G.V.D.1
Guzman, J.V.2
Mica, J.T.3
Poolman, B.4
-
8
-
-
0024938653
-
Conformational changes induced by the transforming amino acid substitution in the transmembrane domain of the neu-oncogene-encoded p185 protein
-
Brandt-Rauf P.W., Pincus M.R., Chen J.M. Conformational changes induced by the transforming amino acid substitution in the transmembrane domain of the neu-oncogene-encoded p185 protein. J Protein Chem 1989, 8:749-755.
-
(1989)
J Protein Chem
, vol.8
, pp. 749-755
-
-
Brandt-rauf, P.W.1
Pincus, M.R.2
Chen, J.M.3
-
9
-
-
0025087151
-
Correlation of the transmembrane domain of the neu-oncogene-encoded p185 protein with its function
-
Brandt-Rauf P.W., Rackovsky S., Pincus M.R. Correlation of the transmembrane domain of the neu-oncogene-encoded p185 protein with its function. Proc Natl Acad Sci USA 1990, 87:8660-8664.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 8660-8664
-
-
Brandt-rauf, P.W.1
Rackovsky, S.2
Pincus, M.R.3
-
11
-
-
0029026638
-
Structure and function of voltage-gated ion channels
-
Caterall W.A. Structure and function of voltage-gated ion channels. Annu Rev Biochem 1995, 64:493-531.
-
(1995)
Annu Rev Biochem
, vol.64
, pp. 493-531
-
-
Caterall, W.A.1
-
12
-
-
0037434791
-
Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab
-
Cho H.S., Mason K., Ramyar K.X., et al. Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab. Nature 2003, 421:756-760.
-
(2003)
Nature
, vol.421
, pp. 756-760
-
-
Cho, H.S.1
Mason, K.2
Ramyar, K.X.3
-
13
-
-
0023196582
-
ErbB-2 is a potent oncogene when overex-pressed in NIH/3T3 cells
-
Di Fiore P.P., Pierce J.H., Kraus M.H., Segatto O.S., King R., Aaronson S.A. erbB-2 is a potent oncogene when overex-pressed in NIH/3T3 cells. Science 1987, 237:178-182.
-
(1987)
Science
, vol.237
, pp. 178-182
-
-
Di Fiore, P.P.1
Pierce, J.H.2
Kraus, M.H.3
Segatto, O.S.4
King, R.5
Aaronson, S.A.6
-
14
-
-
0037264633
-
Targeting the Ras signalling pathway in cancer therapy
-
Downward J. Targeting the Ras signalling pathway in cancer therapy. Nat Rev Cancer 2003, 3:11-22.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
15
-
-
0016579644
-
Use of a symmetry condition to compute the conformation of gramicidin S
-
Dygert M., Go N., Scheraga H.A. Use of a symmetry condition to compute the conformation of gramicidin S. Macro-molecules 1975, 8:750-761.
-
(1975)
Macro-molecules
, vol.8
, pp. 750-761
-
-
Dygert, M.1
Go, N.2
Scheraga, H.A.3
-
16
-
-
0020361618
-
Molecular components of the signal sequence that function in the initiation of protein export
-
Emr S.D., Silhavy T.J. Molecular components of the signal sequence that function in the initiation of protein export. J Cell Biol 1982, 95:689-696.
-
(1982)
J Cell Biol
, vol.95
, pp. 689-696
-
-
Emr, S.D.1
Silhavy, T.J.2
-
17
-
-
0019464222
-
The spontaneous insertion of proteins into and across membranes: the helical hairpin hypothesis
-
Engelman A.M., Steitz T.A. The spontaneous insertion of proteins into and across membranes: the helical hairpin hypothesis. Cell 1981, 23:411-422.
-
(1981)
Cell
, vol.23
, pp. 411-422
-
-
Engelman, A.M.1
Steitz, T.A.2
-
18
-
-
0037291769
-
EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization
-
Ferguson K.M., Berger M.B., Mendrola J.M., Cho H., Leahy D.J., Lemmon M.A. EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization. Mol Cell 2003, 11:507-517.
-
(2003)
Mol Cell
, vol.11
, pp. 507-517
-
-
Ferguson, K.M.1
Berger, M.B.2
Mendrola, J.M.3
Cho, H.4
Leahy, D.J.5
Lemmon, M.A.6
-
19
-
-
84946447735
-
Parallelism in conformational energy calculations on proteins: partial structure of interferon
-
M. Dupuis Montreal Symposium on Supercomputer Simulation in Chemistry
-
Gibson K., Chin S., Pincus M.R., Clementi E., Scheraga H.A. Parallelism in conformational energy calculations on proteins: partial structure of interferon. Lecture Notes in Chemistry 1986, Vol. 44:198-213. M. Dupuis (Ed.).
-
(1986)
Lecture Notes in Chemistry
, vol.44
, pp. 198-213
-
-
Gibson, K.1
Chin, S.2
Pincus, M.R.3
Clementi, E.4
Scheraga, H.A.5
-
20
-
-
3543128441
-
Ion channels
-
Sinauer Associates, Inc, Sunderland, Z.W. Hall
-
Hall Z.W. Ion channels. An Introduction to Molecular Neurobiology 1992, 81-118. Sinauer Associates, Inc, Sunderland. Z.W. Hall (Ed.).
-
(1992)
An Introduction to Molecular Neurobiology
, pp. 81-118
-
-
Hall, Z.W.1
-
22
-
-
0027323459
-
Benzodiazepine peptidomimetics: potent inhibitors of ras farnesylation in animal cells
-
James G.L., Goldstein G.L., Brown M.S., et al. Benzodiazepine peptidomimetics: potent inhibitors of ras farnesylation in animal cells. Science 1993, 260:1937-1942.
-
(1993)
Science
, vol.260
, pp. 1937-1942
-
-
James, G.L.1
Goldstein, G.L.2
Brown, M.S.3
-
23
-
-
0022406444
-
Amplification of a novel v-erbB-related gene in a human mammary carcinoma
-
King C.F., Kraus M.H., Aaronson S.A. Amplification of a novel v-erbB-related gene in a human mammary carcinoma. Science 1985, 229:974-976.
-
(1985)
Science
, vol.229
, pp. 974-976
-
-
King, C.F.1
Kraus, M.H.2
Aaronson, S.A.3
-
24
-
-
0022707185
-
McCammon The dynamics of proteins
-
Karplus M., McCammon The dynamics of proteins. Sci Am 1986, 254:42-52.
-
(1986)
Sci Am
, vol.254
, pp. 42-52
-
-
Karplus, M.1
-
25
-
-
0020478686
-
Voltage-dependent transbilayer orientation of melittin
-
Kempf C., Klausner R.D., Weinstein J.N., van Renswoude J., Pincus M.R., Blumenthal R. Voltage-dependent transbilayer orientation of melittin. J Biol Chem 1982, 257:2469-2475.
-
(1982)
J Biol Chem
, vol.257
, pp. 2469-2475
-
-
Kempf, C.1
Klausner, R.D.2
Weinstein, J.N.3
van Renswoude, J.4
Pincus, M.R.5
Blumenthal, R.6
-
26
-
-
0030575937
-
Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain
-
Kussie P.H., Gorina S., Marechal V., et al. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science 1996, 274:921-922.
-
(1996)
Science
, vol.274
, pp. 921-922
-
-
Kussie, P.H.1
Gorina, S.2
Marechal, V.3
-
28
-
-
0000925139
-
Calculation of the structure of collagen models. Role of interchain interactions in determining the triple helical coiled coil conformation
-
Miller M.H., Scheraga H.A. Calculation of the structure of collagen models. Role of interchain interactions in determining the triple helical coiled coil conformation. J Polymer Sci 1976, 54:171-200.
-
(1976)
J Polymer Sci
, vol.54
, pp. 171-200
-
-
Miller, M.H.1
Scheraga, H.A.2
-
29
-
-
0029559136
-
Structural effects of the binding of GTP to the wild-type and oncogenic forms of the ras-gene-encoded p21 proteins
-
Monaco R., Chen J.M., Friedman F.K., Brandt-Rauf P.W., Pincus M.R. Structural effects of the binding of GTP to the wild-type and oncogenic forms of the ras-gene-encoded p21 proteins. J Protein Chem 1995, 14:721-730.
-
(1995)
J Protein Chem
, vol.14
, pp. 721-730
-
-
Monaco, R.1
Chen, J.M.2
Friedman, F.K.3
Brandt-rauf, P.W.4
Pincus, M.R.5
-
30
-
-
0020117514
-
Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastomas
-
Padhy L.C., Shih C., Cowing D., Finkelstein R., Weinberg R.A. Identification of a phosphoprotein specifically induced by the transforming DNA of rat neuroblastomas. Cell 1982, 28:865-871.
-
(1982)
Cell
, vol.28
, pp. 865-871
-
-
Padhy, L.C.1
Shih, C.2
Cowing, D.3
Finkelstein, R.4
Weinberg, R.A.5
-
31
-
-
84990658268
-
The chain build-up procedure in computing the structures of biologically active polypeptides and proteins
-
Pincus M.R. The chain build-up procedure in computing the structures of biologically active polypeptides and proteins. Int J Quant Chem: Quant Biol Symp 1988, 15:209-220.
-
(1988)
Int J Quant Chem: Quant Biol Symp
, vol.15
, pp. 209-220
-
-
Pincus, M.R.1
-
32
-
-
0019906793
-
Prediction of the three-dimensional structure of the leader sequence of murine pre-kappa light chain, a hexadecapeptide
-
Pincus M.R., Klausner R.D. Prediction of the three-dimensional structure of the leader sequence of murine pre-kappa light chain, a hexadecapeptide. Proc Natl Acad Sci USA 1982, 79:3413-3417.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 3413-3417
-
-
Pincus, M.R.1
Klausner, R.D.2
-
33
-
-
12744264100
-
Conformational analysis of biologically active polypeptides, with application to oncogenesis
-
Pincus M.R., Scheraga H.A. Conformational analysis of biologically active polypeptides, with application to oncogenesis. Accnt Chem Res 1985, 18:372-379.
-
(1985)
Accnt Chem Res
, vol.18
, pp. 372-379
-
-
Pincus, M.R.1
Scheraga, H.A.2
-
34
-
-
0020170122
-
Calculation of the three-dimensional structure of the membrane-bound portion of melittin from its amino acid sequence
-
Pincus M.R., Klausner R.D., Scheraga H.A. Calculation of the three-dimensional structure of the membrane-bound portion of melittin from its amino acid sequence. Proc Natl Acad Sci USA 1982, 79:5107-5110.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 5107-5110
-
-
Pincus, M.R.1
Klausner, R.D.2
Scheraga, H.A.3
-
35
-
-
0033950650
-
Ras-p21-induced cell transformation: unique signal transduction pathways and implications for the design of new chemotherapeutic agents
-
Pincus M.R., Brandt-Rauf P.W., Michl J., Friedman F.K. ras-p21-induced cell transformation: unique signal transduction pathways and implications for the design of new chemotherapeutic agents. Cancer Invest 2000, 18:39-50.
-
(2000)
Cancer Invest
, vol.18
, pp. 39-50
-
-
Pincus, M.R.1
Brandt-rauf, P.W.2
Michl, J.3
Friedman, F.K.4
-
36
-
-
80053494980
-
Oncoproteins and early tumor detection
-
Elsevier, Philadelphia, R. McPherson, M.R. Pincus
-
Pincus M.R., Brandt-Rauf P.W., Bluth M. Oncoproteins and early tumor detection. Henry's Clinical Diagnosis and Management by Laboratory Methods 2006, 1367-1380. Elsevier, Philadelphia. 21st ed. R. McPherson, M.R. Pincus (Eds.).
-
(2006)
Henry's Clinical Diagnosis and Management by Laboratory Methods
, pp. 1367-1380
-
-
Pincus, M.R.1
Brandt-rauf, P.W.2
Bluth, M.3
-
37
-
-
40049088732
-
Anti-cancer peptides from the ras-p21 and p53 proteins
-
Global Research Network Publishers, Kerala, India, R.M. Mohan
-
Pincus M.R., Michl J., Bowne W., Zenilman M. Anti-cancer peptides from the ras-p21 and p53 proteins. Research Advances in Cancer 2007, 65-90. Global Research Network Publishers, Kerala, India. R.M. Mohan (Ed.).
-
(2007)
Research Advances in Cancer
, pp. 65-90
-
-
Pincus, M.R.1
Michl, J.2
Bowne, W.3
Zenilman, M.4
-
38
-
-
1242330299
-
NMR solution structure of a peptide from the mdm-2 binding domain of the p53 protein that is selectively cytotoxic to cancer cells
-
Rosale R., Pincus M.R., Brandt-Rauf P.W., Fine R.L., Michl J., Wang H. NMR solution structure of a peptide from the mdm-2 binding domain of the p53 protein that is selectively cytotoxic to cancer cells. Biochemistry 2004, 43:1754-1861.
-
(2004)
Biochemistry
, vol.43
, pp. 1754-1861
-
-
Rosale, R.1
Pincus, M.R.2
Brandt-rauf, P.W.3
Fine, R.L.4
Michl, J.5
Wang, H.6
-
39
-
-
0019306155
-
Conformational studies of the synthetic precursor-specific region of preproparathyroid hormone
-
Rosenblatt M., Beaudette N.V., Fasman G.D. Conformational studies of the synthetic precursor-specific region of preproparathyroid hormone. Proc Natl Acad Sci USA 1980, 77:3983-3987.
-
(1980)
Proc Natl Acad Sci USA
, vol.77
, pp. 3983-3987
-
-
Rosenblatt, M.1
Beaudette, N.V.2
Fasman, G.D.3
-
40
-
-
0022248941
-
Calculations of electrostatic energies in proteins. The energetics of ionized groups in bovine pancreatic trypsin inhibitor
-
Russell S.T., Warshel A. Calculations of electrostatic energies in proteins. The energetics of ionized groups in bovine pancreatic trypsin inhibitor. J Mol Biol 1985, 185:389-404.
-
(1985)
J Mol Biol
, vol.185
, pp. 389-404
-
-
Russell, S.T.1
Warshel, A.2
-
41
-
-
76649141217
-
Anticancer peptide PNC-27 adopts an HDM-2-binding conformation and kills cancer cells by binding to HDM-2 in their membranes
-
Sarafraz-Yazdi E., Bowne W.B., Adler V., et al. Anticancer peptide PNC-27 adopts an HDM-2-binding conformation and kills cancer cells by binding to HDM-2 in their membranes. Proc Natl Acad Sci USA 2010, 107:1918-1923.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 1918-1923
-
-
Sarafraz-yazdi, E.1
Bowne, W.B.2
Adler, V.3
-
42
-
-
0001931288
-
Protein structure and function, from a colloidal to a molecular point of view
-
Scheraga H.A. Protein structure and function, from a colloidal to a molecular point of view. Carlsberg Res Commun 1984, 49:1-55.
-
(1984)
Carlsberg Res Commun
, vol.49
, pp. 1-55
-
-
Scheraga, H.A.1
-
43
-
-
0011623283
-
Calculations of stable conformations of polypeptides, proteins, and protein complexes
-
Scheraga H.A. Calculations of stable conformations of polypeptides, proteins, and protein complexes. Chim Scripta 1989, 29A:3-13.
-
(1989)
Chim Scripta
, vol.29 A
, pp. 3-13
-
-
Scheraga, H.A.1
-
44
-
-
20044391863
-
The protein folding problem:global optimization of force fields
-
Scheraga H.A., Liwo A., Oldziej S., et al. The protein folding problem:global optimization of force fields. Front Biosci 2004, 9:3296-3323.
-
(2004)
Front Biosci
, vol.9
, pp. 3296-3323
-
-
Scheraga, H.A.1
Liwo, A.2
Oldziej, S.3
-
45
-
-
37049183697
-
Human breast cancer: correlation of relapse and survival with amplification of the her-2/neu oncogene
-
Slamon D.J., Clark G.M., Wong S.G., Levin W.J., Ullrich A., McGuire W.L. Human breast cancer: correlation of relapse and survival with amplification of the her-2/neu oncogene. Science 1987, 235:177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
46
-
-
77956761543
-
Kinetic pathway of antimicrobial peptide magainin 2-induced pore formation in lipid membranes
-
Tamba Y., Arivama H., Levadny V., Yamazaki M. Kinetic pathway of antimicrobial peptide magainin 2-induced pore formation in lipid membranes. J Phys Chem B 2010, 114:2018-2026.
-
(2010)
J Phys Chem B
, vol.114
, pp. 2018-2026
-
-
Tamba, Y.1
Arivama, H.2
Levadny, V.3
Yamazaki, M.4
-
47
-
-
0020079526
-
The structure of melittin in the form I crystals and its implication for melittin's lytic and surface activities
-
Terwilliger T.C., Weissman L., Eisenberg D. The structure of melittin in the form I crystals and its implication for melittin's lytic and surface activities. Biophys J 1982, 37:353-361.
-
(1982)
Biophys J
, vol.37
, pp. 353-361
-
-
Terwilliger, T.C.1
Weissman, L.2
Eisenberg, D.3
-
49
-
-
0001290941
-
Conformational energy calculations on polypeptides and proteins
-
Vasquez M., Nemethy G., Scheraga H.A. Conformational energy calculations on polypeptides and proteins. Chem Rev 1994, 94:2183-2239.
-
(1994)
Chem Rev
, vol.94
, pp. 2183-2239
-
-
Vasquez, M.1
Nemethy, G.2
Scheraga, H.A.3
-
51
-
-
0021170342
-
The p21 ras C-terminus is required for transformation and membrane association
-
Willumsen B.M., Christensen A., Humbert N.L., Papageorge A.G., Lowy D.R. The p21 ras C-terminus is required for transformation and membrane association. Nature 1984, 310:583-586.
-
(1984)
Nature
, vol.310
, pp. 583-586
-
-
Willumsen, B.M.1
Christensen, A.2
Humbert, N.L.3
Papageorge, A.G.4
Lowy, D.R.5
-
53
-
-
0033798839
-
Crystallization of antimicrobial pores in membranes: magainin and protegrin
-
Yang L., Weiss T.M., Lehrer R.I., Huang H.W. Crystallization of antimicrobial pores in membranes: magainin and protegrin. Biophys J 2000, 79:2002-2009.
-
(2000)
Biophys J
, vol.79
, pp. 2002-2009
-
-
Yang, L.1
Weiss, T.M.2
Lehrer, R.I.3
Huang, H.W.4
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