Electroacupuncture preconditioning-induced neuroprotection may be mediated by glutamate transporter type 2

Neurochemistry International

Volumn 63, Issue 4, 2013, Pages 302-308

  Zhu, Xiaoling ^a,b   Yin, Jinbo ^a,c   Li, Liaoliao ^a   Ma, Lei ^b   Tan, Hongying ^a,d   Deng, Jiao ^a,b   Chen, Shaoyang ^b   Zuo, Zhiyi ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c THIRD MILITARY MEDICAL UNIVERSITY   (China)

^d SUN YAT SEN UNIVERSITY   (China)

Author keywords

Brain; Electroacupuncture; Glutamate transporter; Ischemia; Preconditioning

Indexed keywords

DIHYDROKAINIC ACID; EXCITATORY AMINO ACID TRANSPORTER; EXCITATORY AMINO ACID TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 2; EXCITATORY AMINO ACID TRANSPORTER 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION SIZE; BREATHING RATE; CONTROLLED STUDY; ELECTROACUPUNCTURE; HEART RATE; HIPPOCAMPUS; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NEUROLOGIC EXAMINATION; NEUROPROTECTION; NONHUMAN; OUTCOME ASSESSMENT; OXYGEN SATURATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULSE RATE; RAT; SCORING SYSTEM; WESTERN BLOTTING;

MUS; RATTUS;

BRAIN; EA; EAATS; ELECTROACUPUNCTURE; EXCITATORY AMINO ACID TRANSPORTERS; GAPDH; GLUTAMATE TRANSPORTER; GLYCERALDEHYDES 3-PHOSPHATE DEHYDROGENASE; ISCHEMIA; MCAO; MIDDLE CEREBRAL ARTERIAL OCCLUSION; PRECONDITIONING;

AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ELECTROACUPUNCTURE; MALE; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84882484292     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2013.06.017     Document Type: Article

References (27)

1. Arriza, J.L., Fairman, W.A., Wadiche, J.I., Murdoch, G.H., Kavanaugh, M.P., Amara, S.G., 1994. Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. J. Neurosci. 14, 5559-5569. (Pubitemid 24279072)
2. Bigdeli, M.R., Hajizadeh, S., Froozandeh, M., Heidarianpour, A., Rasoulian, B., Asgari, A.R., Pourkhalili, K., Khoshbaten, A., 2008. Normobaric hyperoxia induces ischemic tolerance and upregulation of glutamate transporters in the rat brain and serum TNF-alpha level. Exp. Neurol. 212, 298-306.
3. Chu, K., Lee, S.T., Sinn, D.I., Ko, S.Y., Kim, E.H., Kim, J.M., Kim, S.J., Park, D.K., Jung, K.H., Song, E.C., Lee, S.K., Kim, M., Roh, J.K., 2007. Pharmacological Induction of Ischemic Tolerance by Glutamate Transporter-1 (EAAT2) Upregulation. Stroke 38, 177-182. (Pubitemid 46035624)
4. Danbolt, N.C., 2001. Glutamate uptake. Prog. Neurobiol. 65, 1-105. (Pubitemid 32479155)
5. Dirnagl, U., Simon, R.P., Hallenbeck, J.M., 2003. Ischemic tolerance and endogenous neuroprotection. Trends Neurosci. 26, 248-254. (Pubitemid 36556155)
6. Hoyert, D., Xu, M., 2012. Deaths: preliminary data for 2011. Natl. Vital Stat. Rep. 61, 1-52.
7. Hurtado, O., Pradillo, J.M., Fernandez-Lopez, D., Morales, J.R., Sobrino, T., Castillo, J., Alborch, E., Moro, M.A., Lizasoain, I., 2008. Delayed post-ischemic administration of CDP-choline increases EAAT2 association to lipid rafts and affords neuroprotection in experimental stroke. Neurobiol. Dis. 29, 123-131. (Pubitemid 350180488)
8. Hwang, I.K., Chung, J.Y., Yoo, D.Y., Yi, S.S., Youn, H.Y., Seong, J.K., Yoon, Y.S., 2010. Effects of electroacupuncture at Zusanli and Baihui on brain-derived neurotrophic factor and cyclic AMP response element-binding protein in the hippocampal dentate gyrus. J. Vet. Med. Sci. 72, 1431-1436.
9. Lee, S.N., Li, L., Zuo, Z., 2010. Glutamate transporter type 3 knockout mice have a decreased isoflurane requirement to induce loss of righting reflex. Neuroscience 171, 788-793.
10. Li, L., Zuo, Z., 2009. Isoflurane preconditioning improves short-term and long-term neurological outcome after focal brain ischemia in adult rats. Neuroscience 164, 497-506.
11. Li, L., Zuo, Z., 2011. Glutamate transporter type 3 knockout reduces brain tolerance to focal brain ischemia in mice. J. Cereb. Blood Flow Metab. 31, 1283-1292.
12. Li, X., Luo, P., Wang, Q., Xiong, L., 2012. Electroacupuncture pretreatment as a novel avenue to protect brain against ischemia and reperfusion injury. Evid Based Complement Altern. Med. 2012, 195397.
13. Lipton, P., 1999. Ischemic cell death in brain neurons. Physiol. Rev. 79, 1431-1568. (Pubitemid 29473320)
14. Ma, L., Zhu, Z., Zhao, Y., Hou, L., Wang, Q., Xiong, L., Zhu, X., Jia, J., Chen, S., 2011. Cannabinoid receptor type 2 activation yields delayed tolerance to focal cerebral ischemia. Curr. Neurovasc. Res. 8, 145-152.
15. Mallolas, J., Hurtado, O., Castellanos, M., Blanco, M., Sobrino, T., Serena, J., Vivancos, J., Castillo, J., Lizasoain, I., Moro, M.A., Davalos, A., 2006. A polymorphism in the EAAT2 promoter is associated with higher glutamate concentrations and higher frequency of progressing stroke. J. Exp. Med. 203, 711-717.
16. Peghini, P., Janzen, J., Stoffel, W., 1997. Glutamate transporter EAAC-1-deficient mice develop dicarboxylic aminoaciduria and behavioral abnormalities but no neurodegeneration. EMBO J. 16, 3822-3832. (Pubitemid 27280998)
17. Rao, V.L., Dogan, A., Todd, K.G., Bowen, K.K., Kim, B.T., Rothstein, J.D., Dempsey, R.J., 2001. Antisense knockdown of the glial glutamate transporter GLT-1, but not the neuronal glutamate transporter EAAC1, exacerbates transient focal cerebral ischemia-induced neuronal damage in rat brain. J. Neurosci. 21, 1876-1883. (Pubitemid 32221371)
18. Romera, C., Hurtado, O., Mallolas, J., Pereira, M.P., Morales, J.R., Romera, A., Serena, J., Vivancos, J., Nombela, F., Lorenzo, P., Lizasoain, I., Moro, M.A., 2007. Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection. J. Cereb. Blood Flow Metab. 27, 1327-1338. (Pubitemid 46985349)
19. Rothstein, J.D., Dykes-Hoberg, M., Pardo, C.A., Bristol, L.A., Jin, L., Kuncl, R.W., Kanai, Y., Hediger, M.A., Wang, Y., Schielke, J.P., Welty, D.F., 1996. Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate. Neuron 16, 675-686. (Pubitemid 26103145)
20. Silva, A.J., Simpson, E.M., Takahashi, J.S., Lipp, H.-P., Nakanishi, S., Wehner, J.M., Giese, K.P., Tully, T., Abel, T., Chapman, P.F., Fox, K., Grant, S., Itohara, S., Lathe, R., Mayford, M., McNamara, J.O., Morris, R.J., Picciotto, M., Roder, J., Shin, H.-S., 1997. Mutant mice and neuroscience: recommendations concerning genetic background. Banbury Conference on genetic background in mice. Neuron 19, 755-759.
21. Swanson, R.A., Morton, M.T., Tsao-Wu, G., Savalos, R.A., Davidson, C., Sharp, F.R., 1990. A semiautomated method for measuring brain infarct volume. J. Cereb. Blood Flow Metab. 10, 290-293. (Pubitemid 20096202)
22. Wang, C., Lee, J., Jung, H., Zuo, Z., 2007. Pretreatment with volatile anesthetics, but not with the nonimmobilizer 1,2-dichlorohexafluorocyclobutane, reduced cell injury in rat cerebellar slices after an in vitro simulated ischemia. Brain Res. 1152, 201-208. (Pubitemid 46805156)
23. Wang, Q., Peng, Y., Chen, S., Gou, X., Hu, B., Du, J., Lu, Y., Xiong, L., 2009. Pretreatment with electroacupuncture induces rapid tolerance to focal cerebral ischemia through regulation of endocannabinoid system. Stroke 40, 2157-2164.
24. Won, S.J., Yoo, B.H., Brennan, A.M., Shin, B.S., Kauppinen, T.M., Berman, A.E., Swanson, R.A., Suh, S.W., 2010. EAAC1 gene deletion alters zinc homeostasis and exacerbates neuronal injury after transient cerebral ischemia. J. Neurosci. 30, 15409-15418.
25. Xiong, L., Lu, Z., Hou, L., Zheng, H., Zhu, Z., Wang, Q., Chen, S., 2003. Pretreatment with repeated electroacupuncture attenuates transient focal cerebral ischemic injury in rats. Chin. Med. J. (Engl) 116, 108-111. (Pubitemid 36432734)
26. Zheng, S., Zuo, Z., 2003. Isoflurane preconditioning reduces Purkinje cell death in an in vitro model of rat cerebellar ischemia. Neuroscience 118, 99-106. (Pubitemid 36369534)
27. Zheng, S., Zuo, Z., 2004. Isoflurane preconditioning induces neuroprotection against ischemia via activation of P38 mitogen-activated protein kinases. Mol. Pharmacol. 65, 1172-1180. (Pubitemid 38552356)